메뉴 건너뛰기




Volumn 81, Issue 8, 2013, Pages 2678-2685

Shiga toxin 2 reduces complement inhibitor CD59 expression on human renal tubular epithelial and glomerular endothelial cells

Author keywords

[No Author keywords available]

Indexed keywords

CD59 ANTIGEN; DECAY ACCELERATING FACTOR; MEMBRANE COFACTOR PROTEIN; VEROTOXIN 2;

EID: 84880648308     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01079-12     Document Type: Article
Times cited : (37)

References (47)
  • 1
    • 24044469996 scopus 로고    scopus 로고
    • Enterohaemorrhagic Esche-richia coli in human medicine
    • Karch H, Tarr PI, Bielaszewska M. 2005. Enterohaemorrhagic Esche-richia coli in human medicine. Int. J. Med. Microbiol. 295:405-418.
    • (2005) Int. J. Med. Microbiol , vol.295 , pp. 405-418
    • Karch, H.1    Tarr, P.I.2    Bielaszewska, M.3
  • 2
    • 35548955176 scopus 로고    scopus 로고
    • The Shiga toxin genotype rather than the amount of Shiga toxin or the cyto-toxicity of Shiga toxin in vitro correlates with the appearance of the hemolytic uremic syndrome
    • Orth D, Grif K, Khan AB, Naim A, Dierich MP, Würzner R. 2007. The Shiga toxin genotype rather than the amount of Shiga toxin or the cyto-toxicity of Shiga toxin in vitro correlates with the appearance of the hemolytic uremic syndrome. Diagn. Microbiol. Infect. Dis. 59:235-242.
    • (2007) Diagn. Microbiol. Infect. Dis. , vol.59 , pp. 235-242
    • Orth, D.1    Grif, K.2    Khan, A.B.3    Naim, A.4    Dierich, M.P.5    Würzner, R.6
  • 4
    • 79953313811 scopus 로고    scopus 로고
    • Shiga toxin glycosphingolipid receptors in microvascular and macrovascular endothelial cells: differential association with membrane lipid raft microdomains
    • Betz J, Bielaszewska M, Thies A, Humpf HU, Dreisewerd K, Karch H, Kim KS, Friedrich AW, Müthing J. 2011. Shiga toxin glycosphingolipid receptors in microvascular and macrovascular endothelial cells: differential association with membrane lipid raft microdomains. J. Lipid Res. 52: 618-634.
    • (2011) J. Lipid Res. , vol.52 , pp. 618-634
    • Betz, J.1    Bielaszewska, M.2    Thies, A.3    Humpf, H.U.4    Dreisewerd, K.5    Karch, H.6    Kim, K.S.7    Friedrich, A.W.8    Müthing, J.9
  • 5
    • 84859840087 scopus 로고    scopus 로고
    • Uncommon membrane distribution of Shiga toxin glycosphingolipid receptors in toxin-sensitive human glomerular microvascular endothelial cells
    • Betz J, Bauwens A, Kunsmann L, Bielaszewska M, Mormann M, Humpf HU, Karch H, Friedrich AW, Müthing J. 2012. Uncommon membrane distribution of Shiga toxin glycosphingolipid receptors in toxin-sensitive human glomerular microvascular endothelial cells. Biol. Chem. 393:133-147.
    • (2012) Biol. Chem. , vol.393 , pp. 133-147
    • Betz, J.1    Bauwens, A.2    Kunsmann, L.3    Bielaszewska, M.4    Mormann, M.5    Humpf, H.U.6    Karch, H.7    Friedrich, A.W.8    Müthing, J.9
  • 6
    • 79952087639 scopus 로고    scopus 로고
    • Escherichia coli Shiga toxin mechanismsofaction in renal disease
    • ObrigTG. 2011. Escherichia coli Shiga toxin mechanismsofaction in renal disease. Toxins (Basel) 2:2769-2794.
    • (2011) Toxins (Basel) , vol.2 , pp. 2769-2794
    • Obrig, T.G.1
  • 9
    • 79956293593 scopus 로고    scopus 로고
    • Complement activation on platelet-leukocyte complexes and microparticles in enterohemorrhagic Esche-richia coli-induced hemolytic uremic syndrome
    • Ståhl AL, Sartz L, Karpman D. 2011. Complement activation on platelet-leukocyte complexes and microparticles in enterohemorrhagic Esche-richia coli-induced hemolytic uremic syndrome. Blood 117:5503-5513.
    • (2011) Blood , vol.117 , pp. 5503-5513
    • Ståhl, A.L.1    Sartz, L.2    Karpman, D.3
  • 11
    • 80155167232 scopus 로고    scopus 로고
    • Inhibition of terminal complement activation in severe Shiga toxin-associated HUS-perfect example for a fast track from bench to bedside
    • Orth-Höller D, Riedl M, Würzner R. 2011. Inhibition of terminal complement activation in severe Shiga toxin-associated HUS-perfect example for a fast track from bench to bedside. EMBO Mol. Med. 3:617-619.
    • (2011) EMBO Mol. Med. , vol.3 , pp. 617-619
    • Orth-Höller, D.1    Riedl, M.2    Würzner, R.3
  • 13
    • 84855256386 scopus 로고    scopus 로고
    • Is complement a culprit in infection-induced forms of haemolytic uraemic syndrome
    • Johnson S, Waters A. 2012. Is complement a culprit in infection-induced forms of haemolytic uraemic syndrome? Immunobiology 217:235-243.
    • (2012) Immunobiology , vol.217 , pp. 235-243
    • Johnson, S.1    Waters, A.2
  • 15
    • 70349437186 scopus 로고    scopus 로고
    • Complement regulators and inhibitory proteins
    • Zipfel PF, Skerka C. 2009. Complement regulators and inhibitory proteins. Nat. Rev. Immunol. 9:729-740.
    • (2009) Nat. Rev. Immunol , vol.9 , pp. 729-740
    • Zipfel, P.F.1    Skerka, C.2
  • 17
    • 4644366103 scopus 로고    scopus 로고
    • Complement inhibitor membrane cofactor protein (MCP; CD46)isconstitutively shed from cancer cell membranes in vesicles and converted by a metalloproteinase to a functionally active soluble form
    • Hakulinen J, Junnikkala S, Sorsa T, Meri S. 2004. Complement inhibitor membrane cofactor protein (MCP; CD46)isconstitutively shed from cancer cell membranes in vesicles and converted by a metalloproteinase to a functionally active soluble form. Eur. J. Immunol. 34:2620-2629.
    • (2004) Eur. J. Immunol , vol.34 , pp. 2620-2629
    • Hakulinen, J.1    Junnikkala, S.2    Sorsa, T.3    Meri, S.4
  • 18
    • 0022517078 scopus 로고
    • Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage ofC3b and C4b
    • Seya T, Turner JR, Atkinson JP. 1986. Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage ofC3b and C4b. J. Exp. Med. 163:837-855.
    • (1986) J. Exp. Med. , vol.163 , pp. 837-855
    • Seya, T.1    Turner, J.R.2    Atkinson, J.P.3
  • 19
    • 0025847781 scopus 로고
    • Membrane cofactor protein (MCP or CD46): newest member of the regulators of complement activation gene cluster
    • Liszewski MK, Post TW, Atkinson JP. 1991. Membrane cofactor protein (MCP or CD46): newest member of the regulators of complement activation gene cluster. Annu. Rev. Immunol. 9:431-455.
    • (1991) Annu. Rev. Immunol , vol.9 , pp. 431-455
    • Liszewski, M.K.1    Post, T.W.2    Atkinson, J.P.3
  • 20
    • 0021713655 scopus 로고
    • Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes
    • Medof ME, Kinoshita T, Nussenzweig V. 1984. Inhibition of complement activation on the surface of cells after incorporation of decay-accelerating factor (DAF) into their membranes. J. Exp. Med. 160:1558-1578.
    • (1984) J. Exp. Med. , vol.160 , pp. 1558-1578
    • Medof, M.E.1    Kinoshita, T.2    Nussenzweig, V.3
  • 21
    • 0025179976 scopus 로고
    • Human protectin (CD59), an18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers
    • Meri S, Morgan BP, Davies A, Daniels RH, Olavesen MG, Waldmann H, Lachmann PJ. 1990. Human protectin (CD59), an18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers. Immunology 71:1-9.
    • (1990) Immunology , vol.71 , pp. 1-9
    • Meri, S.1    Morgan, B.P.2    Davies, A.3    Daniels, R.H.4    Olavesen, M.G.5    Waldmann, H.6    Lachmann, P.J.7
  • 22
    • 0031759886 scopus 로고    scopus 로고
    • Complement regulatory proteins in glomerular diseases
    • Nangaku M. 1998. Complement regulatory proteins in glomerular diseases. Kidney Int. 54:1419-1428.
    • (1998) Kidney Int. , vol.54 , pp. 1419-1428
    • Nangaku, M.1
  • 25
    • 70350593605 scopus 로고    scopus 로고
    • Statin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis
    • Kinderlerer AR, Steinberg R, Johns M, Harten SK, Lidington EA, Haskard DO, Maxwell PH, Mason JC. 2006. Statin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis. Arthritis Res. Ther. 8:R130. doi: 10.1186/ar2019.
    • (2006) Arthritis Res. Ther. , vol.8
    • Kinderlerer, A.R.1    Steinberg, R.2    Johns, M.3    Harten, S.K.4    Lidington, E.A.5    Haskard, D.O.6    Maxwell, P.H.7    Mason, J.C.8
  • 28
    • 0028946568 scopus 로고
    • Crry and CD59 regulate complement in rat glomerular epithelial cells and are inhibited by the nephritogenic antibody of passive Heymann nephritis
    • Quigg RJ, Holers VM, Morgan BP, Sneed AE, III. 1995. Crry and CD59 regulate complement in rat glomerular epithelial cells and are inhibited by the nephritogenic antibody of passive Heymann nephritis. J. Immunol. 154:3437-3443.
    • (1995) J. Immunol , vol.154 , pp. 3437-3443
    • Quigg, R.J.1    Holers, V.M.2    Morgan, B.P.3    Sneed III, A.E.4
  • 29
    • 0029084359 scopus 로고
    • Complement regulation in the rat glomerulus: Crry and CD59 regulate complement in glomerular mesangial and endothelial cells
    • Quigg RJ, Morgan BP, Holers VM, Adler S, Sneed AE, III, Lo CF. 1995. Complement regulation in the rat glomerulus: Crry and CD59 regulate complement in glomerular mesangial and endothelial cells. Kidney Int. 48:412-421.
    • (1995) Kidney Int. , vol.48 , pp. 412-421
    • Quigg, R.J.1    Morgan, B.P.2    Holers, V.M.3    Adler, S.4    Sneed III, A.E.5    Lo, C.F.6
  • 30
    • 0027504646 scopus 로고
    • Immu-nolocalization and characterization of the rat analogue of human CD59 in kidney and glomerular cells
    • Hughes TR, Meri S, Davies M, Williams JD, Morgan BP. 1993. Immu-nolocalization and characterization of the rat analogue of human CD59 in kidney and glomerular cells. Immunology 80:439-444.
    • (1993) Immunology , vol.80 , pp. 439-444
    • Hughes, T.R.1    Meri, S.2    Davies, M.3    Williams, J.D.4    Morgan, B.P.5
  • 34
    • 84855362194 scopus 로고    scopus 로고
    • Mechanisms and clinical implications of thrombosis in paroxysmal nocturnal hemoglobinuria
    • van Bijnen ST, van Heerde WL, Muus P. 2012. Mechanisms and clinical implications of thrombosis in paroxysmal nocturnal hemoglobinuria. J. Thromb. Haemost. 10:1-10.
    • (2012) J. Thromb. Haemost , vol.10 , pp. 1-10
    • van Bijnen, S.T.1    van Heerde, W.L.2    Muus, P.3
  • 35
    • 70450224086 scopus 로고    scopus 로고
    • Hepatitis B virus sensitizes hepatocytes to complement-dependent cytotoxicity through downregulating CD59
    • Qu Z, Liang X, Liu Y, Du J, Liu S, Sun W. 2009. Hepatitis B virus sensitizes hepatocytes to complement-dependent cytotoxicity through downregulating CD59. Mol. Immunol. 47:283-289.
    • (2009) Mol. Immunol , vol.47 , pp. 283-289
    • Qu, Z.1    Liang, X.2    Liu, Y.3    Du, J.4    Liu, S.5    Sun, W.6
  • 36
  • 38
    • 84859341542 scopus 로고    scopus 로고
    • Hemolytic uremic syndrome: new developments in pathogenesis and treatment
    • doi: 10.4061/2011/908407
    • Boyer O, Niaudet P. 2011. Hemolytic uremic syndrome: new developments in pathogenesis and treatment. Int. J. Nephrol. 2011:908407. doi: 10.4061/2011/908407.
    • (2011) Int. J. Nephrol , vol.2011 , pp. 908407
    • Boyer, O.1    Niaudet, P.2
  • 39
    • 33645079378 scopus 로고    scopus 로고
    • Complement regulator loss on apoptotic neuronal cells causes increased complement activation and promotes both phagocytosis and cell lysis
    • Cole DS, Hughes TR, Gasque P, Morgan BP. 2006. Complement regulator loss on apoptotic neuronal cells causes increased complement activation and promotes both phagocytosis and cell lysis. Mol. Immunol. 43:1953-1964.
    • (2006) Mol. Immunol , vol.43 , pp. 1953-1964
    • Cole, D.S.1    Hughes, T.R.2    Gasque, P.3    Morgan, B.P.4
  • 40
    • 0029586946 scopus 로고
    • Apoptosis is associated with reduced expression of complement regulatory molecules, adhesion molecules and other receptors on polymorphonuclear leucocytes: functional relevance and role in inflammation
    • Jones J, Morgan BP. 1995. Apoptosis is associated with reduced expression of complement regulatory molecules, adhesion molecules and other receptors on polymorphonuclear leucocytes: functional relevance and role in inflammation. Immunology 86:651-660.
    • (1995) Immunology , vol.86 , pp. 651-660
    • Jones, J.1    Morgan, B.P.2
  • 41
    • 0032895968 scopus 로고    scopus 로고
    • Transforming growth factor-beta isoforms regulate the surface expression of membrane cofac-tor protein (CD46) and CD59 on human keratinocytes
    • Pasch MC, Bos JD, Daha MR, Asghar SS. 1999. Transforming growth factor-beta isoforms regulate the surface expression of membrane cofac-tor protein (CD46) and CD59 on human keratinocytes. Eur. J. Immunol. 29:100-108.
    • (1999) Eur. J. Immunol , vol.29 , pp. 100-108
    • Pasch, M.C.1    Bos, J.D.2    Daha, M.R.3    Asghar, S.S.4
  • 43
    • 0032237963 scopus 로고    scopus 로고
    • Globotriaosyl ceramide (Gb3) expression in human tumour cells: intracellular trafficking defines a new retrograde transport pathway from the cell surface to the nucleus, which correlates with sensitivity to verotoxin
    • Lingwood CA, Khine AA, Arab S. 1998. Globotriaosyl ceramide (Gb3) expression in human tumour cells: intracellular trafficking defines a new retrograde transport pathway from the cell surface to the nucleus, which correlates with sensitivity to verotoxin. Acta Biochim. Pol. 45:351-359.
    • (1998) Acta Biochim. Pol. , vol.45 , pp. 351-359
    • Lingwood, C.A.1    Khine, A.A.2    Arab, S.3
  • 44
    • 0031822654 scopus 로고    scopus 로고
    • CD77-dependent retrograde transport of CD19 to the nuclear membrane: functional relationship between CD77 and CD19 during germinal center B-cell apoptosis
    • Khine AA, Firtel M, Lingwood CA. 1998. CD77-dependent retrograde transport of CD19 to the nuclear membrane: functional relationship between CD77 and CD19 during germinal center B-cell apoptosis. J. Cell. Physiol. 176:281-292.
    • (1998) J. Cell. Physiol , vol.176 , pp. 281-292
    • Khine, A.A.1    Firtel, M.2    Lingwood, C.A.3
  • 46
    • 0024579910 scopus 로고
    • Verotoxin receptor glycolipid in human renal tissue
    • Boyd B, Lingwood C. 1989. Verotoxin receptor glycolipid in human renal tissue. Nephron 51:207-210.
    • (1989) Nephron , vol.51 , pp. 207-210
    • Boyd, B.1    Lingwood, C.2
  • 47
    • 0028366473 scopus 로고
    • Verotoxin-binding in human renal sections
    • Lingwood CA. 1994. Verotoxin-binding in human renal sections. Nephron 66:21-28.
    • (1994) Nephron , vol.66 , pp. 21-28
    • Lingwood, C.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.