Pharmacology of local anesthetics used in oral surgery

Oral and Maxillofacial Surgery Clinics of North America

Volumn 25, Issue 3, 2013, Pages 453-465

  Giovannitti, Joseph A ^a   Rosenberg, Morton B ^b,c   Phero, James C ^d  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b TUFTS UNIVERSITY SCHOOL OF DENTAL MEDICINE   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Complications and reasons for failure; Future trends; Local anesthetics; Pharmacology

Indexed keywords

BUFFER; LOCAL ANESTHETIC AGENT; VASOCONSTRICTOR AGENT;

CHEMISTRY; COMPLICATIONS AND REASONS FOR FAILURE; DENTAL ANESTHESIA; DRUG EFFECT; FUTURE TRENDS; HUMAN; LOCAL ANESTHESIA; LOCAL ANESTHETICS; NERVE FIBER; ORAL SURGERY; PHARMACOLOGY; REVIEW;

COMPLICATIONS AND REASONS FOR FAILURE; FUTURE TRENDS; LOCAL ANESTHETICS; PHARMACOLOGY;

ANESTHESIA, DENTAL; ANESTHESIA, LOCAL; ANESTHETICS, LOCAL; BUFFERS; CHEMISTRY, PHARMACEUTICAL; HUMANS; NERVE FIBERS; ORAL SURGICAL PROCEDURES; VASOCONSTRICTOR AGENTS;

EID: 84880636241     PISSN: 10423699     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coms.2013.03.003     Document Type: Review

References (40)

1. Franz D.N., Perry R.S. Mechanisms for differential block among single myelinated and nonmyelinated axons by procaine. JPhysiol 1974, 236:193-210.
2. + channel TASK-2 (KCNK5). JPharmacol Exp Ther 2003, 306:84-92.
3. Tsuchiya H., Ueno T., Mizogami M. Stereostructure-based differences in the interactions of cardiotoxic local anesthetics with cholesterol-containing biomimetic membranes. Bioorg Med Chem 2011, 19:3410-3415.
4. Yagiela J.A. Local Anesthetics. Pharmacology and therapeutics for dentistry 2010, 256. Mosby Elsevier, St Louis (MO). 6th edition. J.A. Yagiela, F.J. Dowd, B.S. Johnson (Eds.).
5. American Dental Association 2002 survey of dental practice: characteristics of dentists in prive practice & their patients 2002, American Dental Association, Chicago.
6. Haas D.A., Lennon D. A21 year retrospective study of reports of paresthesia following local anesthetic administration. JCan Dent Assoc 1995, 61:319-330.
7. Malamed S.F., Gagnon S., Leblanc D. Efficacy of articaine: a new amide local anesthetic. JAm Dent Assoc 2000, 131(5):635-642.
8. Abdulwahab M., Boynes S., Moore P., et al. The efficacy of six local anesthetic formulations used for posterior mandibular buccal infiltration anesthesia. JAm Dent Assoc 2009, 140:1018-1024.
9. Mito R.S., Yagiela J.A. Hypertensive response to levonordefrin in a patient receiving propranolol: report of a case. JAm Dent Assoc 1988, 116:55-57.
10. Cryer P.E. Physiology and pathophysiology of the human sympathoadrenal neuroendocrine system. NEngl J Med 1980, 303(8):436-444.
11. Bennett C.R. Monheim's local anesthesia and pain control in dental practice 1984, Mosby, St Louis (MO). 7th edition.
12. Cioffi G.A., Chernow B., Glahn R.P., et al. The hemodynamic and plasma catecholamine responses to routine restorative dental care. JAm Dent Assoc 1985, 111(1):67-70.
13. Sung B.H., Wilson M.F., Robinson C., et al. Mechanisms of myocardial ischemia induced by epinephrine: comparison with exercise-induced ischemia. Psychosom Med 1988, 50:381-393.
14. Finder R.L., Moore P.A. Adverse drug reactions to local anesthesia. Dent Clin North Am 2002, 46:747-757.
15. AAPD Guideline on Use of Local Anesthetics for Pediatric Dental Patients. Adopted 2005, Revised 2009. Available at: Accessed July 16, 2012. http://www.aapd.org/media/Policies_Guidelines/G_LocalAnesthesia.pdf.
16. Goodson J.M., Moore P.A. Life-threatening reactions after pedodontic sedation: an assessment of narcotic, local anesthetic, and antiemetic drug interaction. JAm Dent Assoc 1983, 107:239-245.
17. Hersh E.V., Moore P.A., Papas A.S., et al. Reversal of soft-tissue local anesthesia with phentolamine mesylate in adolescents and adults. JAm Dent Assoc 2008, 139:1080-1093.
18. Tavares M., Goodson J.M., Studen-Pavlovich D., et al. Reversal of soft-tissue local anesthesia with phentolamine mesylate in pediatric patients. JAm Dent Assoc 2008, 139:1095-1104.
19. Weinberg G.L., VadeBoncouer T., Ramaraju G.A., et al. Pretreatment or resuscitation with a lipid infusion shifts the dose-response curve to bupivacaine-induced asystole in rats. Anesthesiology 1998, 88:1071-1075.
20. Litz R.J., Popp M., Stehr S.N., et al. Successful resuscitation of a patient with ropivacaine-induced asystole after axillary plexus block using lipid infusion. Anaesthesia 2006, 61:800-801.
21. Rosenblatt M.A., Abel M., Fischer G.W., et al. Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest. Anesthesiology 2006, 105:217-218.
22. Vanden Hock T.L., Morrison L.J., Shuster M., et al. Part 12: cardiac arrest in special situations: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 2010, 122:S843.
23. Galindo A. pH-adjusted local anesthetics: clinical experience. Reg Anesth 1983, 8:35-36.
24. Benzon H.T., Toleikis J.R., Dixit P., et al. Onset intensity of blockade and somatosensory evoked potential changes of the lumbosacral dermatomes after epidural anesthesia with alkalinized lidocaine. Anesth Analg 1993, 76:328-332.
25. Whitcomb M., Drum M., Reader A., et al. Aprospective, randomized, double-blind study of the anesthetic efficacy of sodium bicarbonate buffered 2% lidocaine with 1:100,000 epinephrine in inferior alveolar nerve blocks. Anesth Prog 2010, 57:59-66.
26. 14C)-sucrose by stretch and hypertonicity. Brain Res 1979, 173:503-512.
27. Antonijevic I., Mousa S., Schafer M., et al. Perineural defect and peripheral opioid analgesia in inflammation. JNeurosci 1995, 15:165-172.
28. Wolf R., Reader A., Drum M., et al. Mannitol and lidocaine with epinephrine in inferior alveolar nerve blocks: a prospective randomized, single-blind study. Anesth Prog 2011, 58:157-165.
29. Gorfine S.R., Onel E., Patou G., et al. Bupivacaine extended-release liposome injection for prolonged postsurgical analgesia in patients undergoing hemorrhoidectomy: a multicenter, randomized, double-blind, placebo-controlled trial. Dis Colon Rectum 2011, 54:1552-1559.
30. Meyer T.N., Lemos L.L., Nascimento C.N.M., et al. Effectiveness of nasopalatine nerve block for anesthesia of maxillary central incisors after failure of the anterior superior alveolar nerve block technique. Braz Dent J 2007, 18:69-73.
31. Blanton P.L., Jeske A.H. The key to profound local anesthesia: neuroanatomy. JAm Dent Assoc 2003, 134:753-760.
32. Noorily A.D., Noorily S.H., Otto R.A. Cocaine, lidocaine, tetracaine: which is best for topical nasal anesthesia?. Anesth Analg 1995, 81:724-727.
33. Reiz S., Haggmark S., Johansson G., et al. Cardiotoxicity of ropivacaine: a new amide local anesthetic agent. Acta Anaesthesiol Scand 1989, 33:93-98.
34. El-Sharrawy E., Yagiela J.A. Anesthetic efficacy of different ropivacaine concentrations for inferior alveolar nerve block. Anesth Prog 2006, 53:3-7.
35. Oliveira N.E., Lima Filho N.S., Lima E.G., et al. Effects of regional anesthesia with ropivacaine on arterial pressure and heart rate in healthy subjects. Eur J Oral Sci 2006, 114:27-32.
36. Brkovic B.M., Zltkovic D., Jovanovic D., et al. Maxillary infiltration anaesthesia by ropivacaine for upper third molar surgery. Int J Oral Maxillofac Surg 2010, 39:36-41.
37. Krzeminski T.F., Gilowski L., Wiench R., et al. Comparison of ropivacaine and lidocaine with epinephrine for infiltration anesthesia in dentistry. A randomized study. Am J Dent 2011, 24:305-309.
38. All-Atabakhsh A., Rosenberg M.B. Ropivacaine: the next dental local anesthetic?. JMass Dent Soc 2012, 61:14-16.
39. Vreeland D.L., Reader A., Beck M., et al. An evaluation of volumes and concentrations of lidocaine in human inferior alveolar nerve block. JEndod 1989, 15:6-12.
40. Daublander M., Kammerer P.W., Willerhausen B., et al. Clinical use of an epinephrine-reduced (1:400,000) articaine solution in short-time dental routine treatments-a multicenter study. Clin Oral Invest 2012, 16(4):1289-1295.