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Volumn 12, Issue 10, 2013, Pages 967-971

Assessment of intracellular cytokines and regulatory cells in patients with autoimmune diseases and primary immunodeficiencies - Novel tool for diagnostics and patient follow-up

Author keywords

Autoimmune diseases; Immunodeficiencies; Immunoregulatory abnormalities; Regulatory T cells; Soluble, intracellular cytokines; Th17 cells

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; SCATTER FACTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 84880575987     PISSN: 15689972     EISSN: 18730183     Source Type: Journal    
DOI: 10.1016/j.autrev.2013.02.003     Document Type: Review
Times cited : (38)

References (66)
  • 1
    • 0034571173 scopus 로고    scopus 로고
    • The molecular basis of T helper 1 and T helper2 cell differentiation
    • O'Garra A., Arai N. The molecular basis of T helper 1 and T helper2 cell differentiation. Trends Cell Biol 2000, 10:542-550.
    • (2000) Trends Cell Biol , vol.10 , pp. 542-550
    • O'Garra, A.1    Arai, N.2
  • 2
    • 33846966636 scopus 로고    scopus 로고
    • H2 hypothesis of T-cell-mediated tissue damage
    • H2 hypothesis of T-cell-mediated tissue damage. Nat Med 2007, 13:139-145.
    • (2007) Nat Med , vol.13 , pp. 139-145
    • Steinman, L.1
  • 3
    • 33751512478 scopus 로고    scopus 로고
    • Development and function of naturally occurring CD4+CD25+ regulatory cells
    • Toda A., Piccirillo C.A. Development and function of naturally occurring CD4+CD25+ regulatory cells. J Leukoc Biol 2006, 80:458-470.
    • (2006) J Leukoc Biol , vol.80 , pp. 458-470
    • Toda, A.1    Piccirillo, C.A.2
  • 4
    • 80855138676 scopus 로고    scopus 로고
    • B-cells and their targeting in rheumatoid arthritis - current concepts and future perspectives
    • Nakken B., Munthe L.A., Konttinen Y.T., Sandberg A.K., Szekanecz Z., Alex P., et al. B-cells and their targeting in rheumatoid arthritis - current concepts and future perspectives. Autoimmun Rev 2011, 11:28-34.
    • (2011) Autoimmun Rev , vol.11 , pp. 28-34
    • Nakken, B.1    Munthe, L.A.2    Konttinen, Y.T.3    Sandberg, A.K.4    Szekanecz, Z.5    Alex, P.6
  • 5
    • 33746796650 scopus 로고    scopus 로고
    • Regulatory T-cells in peripheral blood of patients with mixed connective tissue disease
    • Baráth S., Sipka S., Aleksza M., Szegedi A., Szodoray P., Végh J., et al. Regulatory T-cells in peripheral blood of patients with mixed connective tissue disease. Scand J Rheumatol 2006, 35:300-304.
    • (2006) Scand J Rheumatol , vol.35 , pp. 300-304
    • Baráth, S.1    Sipka, S.2    Aleksza, M.3    Szegedi, A.4    Szodoray, P.5    Végh, J.6
  • 7
    • 0034041342 scopus 로고    scopus 로고
    • Unclassified or undifferentiated connective tissue disease
    • Alarcon G.S. Unclassified or undifferentiated connective tissue disease. Baillieres Best Pract Res Clin Rheumatol 2000, 14:125-137.
    • (2000) Baillieres Best Pract Res Clin Rheumatol , vol.14 , pp. 125-137
    • Alarcon, G.S.1
  • 8
  • 10
    • 0031885809 scopus 로고    scopus 로고
    • Early undifferentiated connective tissue disease. V. An inception cohort 5years later: disease remissions and changes in diagnoses in well established and undifferentiated connective tissue diseases
    • Williams H.J., Alarcón G.S., Neuner R., Steen V.D., Bulpitt K., Clegg D.O., et al. Early undifferentiated connective tissue disease. V. An inception cohort 5years later: disease remissions and changes in diagnoses in well established and undifferentiated connective tissue diseases. J Rheumatol 1998, 25:261-268.
    • (1998) J Rheumatol , vol.25 , pp. 261-268
    • Williams, H.J.1    Alarcón, G.S.2    Neuner, R.3    Steen, V.D.4    Bulpitt, K.5    Clegg, D.O.6
  • 11
    • 0032963535 scopus 로고    scopus 로고
    • Early undifferentiated connective tissue disease (CTD) VI: an inception cohort after 10years: disease remissions and changes in diagnoses in well established and undifferentiated CTD
    • Williams H.J., Alarcon G.S., Joks R., Steen V.D., Bulpitt K., Clegg D.O., et al. Early undifferentiated connective tissue disease (CTD) VI: an inception cohort after 10years: disease remissions and changes in diagnoses in well established and undifferentiated CTD. J Rheumatol 1999, 26:816-825.
    • (1999) J Rheumatol , vol.26 , pp. 816-825
    • Williams, H.J.1    Alarcon, G.S.2    Joks, R.3    Steen, V.D.4    Bulpitt, K.5    Clegg, D.O.6
  • 12
    • 48349093203 scopus 로고    scopus 로고
    • Progressive divergent shifts in natural and induced T-regulatory cells signify the transition from undifferentiated to definitive connective tissue disease
    • Szodoray P., Nakken B., Barath S., Gaal J., Aleksza M., Zeher M., et al. Progressive divergent shifts in natural and induced T-regulatory cells signify the transition from undifferentiated to definitive connective tissue disease. Int Immunol 2008, 20:971-979.
    • (2008) Int Immunol , vol.20 , pp. 971-979
    • Szodoray, P.1    Nakken, B.2    Barath, S.3    Gaal, J.4    Aleksza, M.5    Zeher, M.6
  • 13
    • 78649703599 scopus 로고    scopus 로고
    • Impaired regulatory T-cell homeostasis due to vitamin D deficiency in undifferentiated connective tissue disease
    • Zold E., Szodoray P., Kappelmayer J., Gaal J., Csathy L., Barath S., et al. Impaired regulatory T-cell homeostasis due to vitamin D deficiency in undifferentiated connective tissue disease. Scand J Rheumatol 2010, 39:490-497.
    • (2010) Scand J Rheumatol , vol.39 , pp. 490-497
    • Zold, E.1    Szodoray, P.2    Kappelmayer, J.3    Gaal, J.4    Csathy, L.5    Barath, S.6
  • 14
    • 78751633052 scopus 로고    scopus 로고
    • Alfacalcidol treatment restores derailed immune-regulation in patients with undifferentiated connective tissue disease
    • Zold E., Szodoray P., Nakken B., Barath S., Kappelmayer J., Csathy L., et al. Alfacalcidol treatment restores derailed immune-regulation in patients with undifferentiated connective tissue disease. Autoimmun Rev 2011, 10:155-162.
    • (2011) Autoimmun Rev , vol.10 , pp. 155-162
    • Zold, E.1    Szodoray, P.2    Nakken, B.3    Barath, S.4    Kappelmayer, J.5    Csathy, L.6
  • 15
    • 84876305082 scopus 로고    scopus 로고
    • Sjögren's syndrome
    • Transworld Research Network, Kerala, India, M. Zeher, P. Szodoray (Eds.) Sjögren's syndrome and associated disorders
    • Zeher M. Sjögren's syndrome. Research signpost 2006, 1-7. Transworld Research Network, Kerala, India. M. Zeher, P. Szodoray (Eds.).
    • (2006) Research signpost , pp. 1-7
    • Zeher, M.1
  • 16
    • 84880581530 scopus 로고    scopus 로고
    • Selected molecular aspects behind the clinical picture of Sjögren's syndrome
    • Transworld Research Network, Kerala, India, M. Zeher, P. Szodoray (Eds.) Sjögren's syndrome and associated disorders
    • Szodoray P., Nakken B. Selected molecular aspects behind the clinical picture of Sjögren's syndrome. Research signpost 2006, 27-49. Transworld Research Network, Kerala, India. M. Zeher, P. Szodoray (Eds.).
    • (2006) Research signpost , pp. 27-49
    • Szodoray, P.1    Nakken, B.2
  • 17
    • 2942748333 scopus 로고    scopus 로고
    • Circulating cytokines in primary Sjögren's syndrome determined by a multiplex cytokine array system
    • Szodoray P., Alex P., Brun J.G., Centola M., Jonsson R. Circulating cytokines in primary Sjögren's syndrome determined by a multiplex cytokine array system. Scand J Immunol 2004, 59:592-599.
    • (2004) Scand J Immunol , vol.59 , pp. 592-599
    • Szodoray, P.1    Alex, P.2    Brun, J.G.3    Centola, M.4    Jonsson, R.5
  • 18
    • 0034926257 scopus 로고    scopus 로고
    • Circulating levels of Th1/Th2 cytokines in patients with primary Sjögren's syndrome: correlation with clinical and immunological features
    • Garcíc-Carrasco M., Font J., Filella X., Cervera R., Ramos-Casals M., Sisó A., et al. Circulating levels of Th1/Th2 cytokines in patients with primary Sjögren's syndrome: correlation with clinical and immunological features. Clin Exp Rheumatol 2001, 19:411-415.
    • (2001) Clin Exp Rheumatol , vol.19 , pp. 411-415
    • Garcíc-Carrasco, M.1    Font, J.2    Filella, X.3    Cervera, R.4    Ramos-Casals, M.5    Sisó, A.6
  • 21
    • 45549083564 scopus 로고    scopus 로고
    • Immunological alterations in newly diagnosed primary Sjögren's syndrome characterized by skewed peripheral T-cell subsets and inflammatory cytokines
    • Szodoray P., Gal I., Barath S., Aleksza M., Horvath I.F., Gergely P., et al. Immunological alterations in newly diagnosed primary Sjögren's syndrome characterized by skewed peripheral T-cell subsets and inflammatory cytokines. Scand J Rheumatol 2008, 37:205-212.
    • (2008) Scand J Rheumatol , vol.37 , pp. 205-212
    • Szodoray, P.1    Gal, I.2    Barath, S.3    Aleksza, M.4    Horvath, I.F.5    Gergely, P.6
  • 22
    • 67651236911 scopus 로고    scopus 로고
    • Cells with regulatory function of the innate and adaptive immune system in primary Sjögren's syndrome
    • Szodoray P., Papp G., Horvath I.F., Barath S., Sipka S., Nakken B., et al. Cells with regulatory function of the innate and adaptive immune system in primary Sjögren's syndrome. Clin Exp Immunol 2009, 157:343-349.
    • (2009) Clin Exp Immunol , vol.157 , pp. 343-349
    • Szodoray, P.1    Papp, G.2    Horvath, I.F.3    Barath, S.4    Sipka, S.5    Nakken, B.6
  • 23
    • 26044481687 scopus 로고    scopus 로고
    • Distinct profiles of Sjögren's syndrome patients with ectopic salivary gland germinal centers revealed by serum cytokines and BAFF
    • Szodoray P., Alex P., Jonsson M.V., Knowlton N., Dozmorov I., Nakken B., et al. Distinct profiles of Sjögren's syndrome patients with ectopic salivary gland germinal centers revealed by serum cytokines and BAFF. Clin Immunol 2005, 117:168-176.
    • (2005) Clin Immunol , vol.117 , pp. 168-176
    • Szodoray, P.1    Alex, P.2    Jonsson, M.V.3    Knowlton, N.4    Dozmorov, I.5    Nakken, B.6
  • 24
    • 77950383267 scopus 로고    scopus 로고
    • The immunoregulatory role of vitamins A, D and E in patients with primary Sjogren's syndrome
    • Szodoray P., Horvath I.F., Papp G., Barath S., Gyimesi E., Csathy L., et al. The immunoregulatory role of vitamins A, D and E in patients with primary Sjogren's syndrome. Rheumatology (Oxford) 2010, 49:211-217.
    • (2010) Rheumatology (Oxford) , vol.49 , pp. 211-217
    • Szodoray, P.1    Horvath, I.F.2    Papp, G.3    Barath, S.4    Gyimesi, E.5    Csathy, L.6
  • 25
    • 0034937852 scopus 로고    scopus 로고
    • Criteria for the classification of early systemic sclerosis
    • LeRoy E.C., Medsger T.A. Criteria for the classification of early systemic sclerosis. J Rheumatol 2001, 28:1573-1576.
    • (2001) J Rheumatol , vol.28 , pp. 1573-1576
    • LeRoy, E.C.1    Medsger, T.A.2
  • 26
    • 70350049103 scopus 로고    scopus 로고
    • Abnormal DNA methylation in CD4+ T cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositis
    • Lei W., Luo Y., Lei W., Luo Y., Yan K., Zhao S. Abnormal DNA methylation in CD4+ T cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositis. Scand J Rheumatol 2009, 38:369-374.
    • (2009) Scand J Rheumatol , vol.38 , pp. 369-374
    • Lei, W.1    Luo, Y.2    Lei, W.3    Luo, Y.4    Yan, K.5    Zhao, S.6
  • 27
    • 27744604032 scopus 로고    scopus 로고
    • Abnormal natural killer cell function in systemic sclerosis: altered cytokine production and defective killing activity
    • Horikawa M., Hasegawa M., Komura K., Hayakawa I., Yanaba K., Matsushita T. Abnormal natural killer cell function in systemic sclerosis: altered cytokine production and defective killing activity. J Invest Dermatol 2005, 125:731-737.
    • (2005) J Invest Dermatol , vol.125 , pp. 731-737
    • Horikawa, M.1    Hasegawa, M.2    Komura, K.3    Hayakawa, I.4    Yanaba, K.5    Matsushita, T.6
  • 28
    • 13444309109 scopus 로고    scopus 로고
    • Reduced circulating natural killer T cells and gamma/delta T cells in patients with systemic sclerosis
    • Riccieri V., Parisi G., Spadaro A., Scrivo R., Barone F., Moretti T. Reduced circulating natural killer T cells and gamma/delta T cells in patients with systemic sclerosis. J Rheumatol 2005, 32:283-286.
    • (2005) J Rheumatol , vol.32 , pp. 283-286
    • Riccieri, V.1    Parisi, G.2    Spadaro, A.3    Scrivo, R.4    Barone, F.5    Moretti, T.6
  • 29
    • 77649178968 scopus 로고    scopus 로고
    • Regulatory T cells (CD4(+)CD25(bright)FoxP3(+)) expansion in systemic sclerosis correlates with disease activity and severity
    • Slobodin G., Ahmad M.S., Rosner I., Peri R., Rozenbaum M., Kessel A. Regulatory T cells (CD4(+)CD25(bright)FoxP3(+)) expansion in systemic sclerosis correlates with disease activity and severity. Cell Immunol 2010, 261:77-80.
    • (2010) Cell Immunol , vol.261 , pp. 77-80
    • Slobodin, G.1    Ahmad, M.S.2    Rosner, I.3    Peri, R.4    Rozenbaum, M.5    Kessel, A.6
  • 30
    • 58149485202 scopus 로고    scopus 로고
    • Quantification and molecular characterization of regulatory T cells in connective tissue diseases
    • Banica L., Besliu A., Pistol G., Stavaru C., Ionescu R., Forsea A.M. Quantification and molecular characterization of regulatory T cells in connective tissue diseases. Autoimmunity 2009, 42:41-49.
    • (2009) Autoimmunity , vol.42 , pp. 41-49
    • Banica, L.1    Besliu, A.2    Pistol, G.3    Stavaru, C.4    Ionescu, R.5    Forsea, A.M.6
  • 31
    • 42649134787 scopus 로고    scopus 로고
    • Clinical association of serum interleukin-17 levels in systemic sclerosis: is systemic sclerosis a Th17 disease?
    • Murata M., Fujimoto M., Matsushita T., Hamaguchi Y., Hasegawa M., Takehara K. Clinical association of serum interleukin-17 levels in systemic sclerosis: is systemic sclerosis a Th17 disease?. J Dermatol Sci 2008, 50:240-242.
    • (2008) J Dermatol Sci , vol.50 , pp. 240-242
    • Murata, M.1    Fujimoto, M.2    Matsushita, T.3    Hamaguchi, Y.4    Hasegawa, M.5    Takehara, K.6
  • 32
    • 36549048990 scopus 로고    scopus 로고
    • Possible implication of the effector CD4+ T-cell subpopulation TH17 in the pathogenesis of systemic scleroderma
    • Deleuran B., Abraham D.J. Possible implication of the effector CD4+ T-cell subpopulation TH17 in the pathogenesis of systemic scleroderma. Nat Clin Pract Rheumatol 2007, 3:682-683.
    • (2007) Nat Clin Pract Rheumatol , vol.3 , pp. 682-683
    • Deleuran, B.1    Abraham, D.J.2
  • 33
    • 2642588319 scopus 로고    scopus 로고
    • Is systemic sclerosis an antigen-driven T cell disease?
    • Sakkas L.I., Platsoucas C.D. Is systemic sclerosis an antigen-driven T cell disease?. Arthritis Rheum 2004, 50:1721-1733.
    • (2004) Arthritis Rheum , vol.50 , pp. 1721-1733
    • Sakkas, L.I.1    Platsoucas, C.D.2
  • 34
    • 79955618079 scopus 로고    scopus 로고
    • Altered T-cell and regulatory cell repertoire in patients with diffuse cutaneous systemic sclerosis
    • Papp G., Horvath I.F., Barath S., Gyimesi E., Sipka S., Szodoray P., et al. Altered T-cell and regulatory cell repertoire in patients with diffuse cutaneous systemic sclerosis. Scand J Rheumatol 2011, 40:205-210.
    • (2011) Scand J Rheumatol , vol.40 , pp. 205-210
    • Papp, G.1    Horvath, I.F.2    Barath, S.3    Gyimesi, E.4    Sipka, S.5    Szodoray, P.6
  • 35
    • 84856550315 scopus 로고    scopus 로고
    • Immunomodulatory effects of extracorporeal photochemotherapy in systemic sclerosis
    • Papp G., Horvath I.F., Barath S., Gyimesi E., Vegh J., Szodoray P., et al. Immunomodulatory effects of extracorporeal photochemotherapy in systemic sclerosis. Clin Immunol 2012, 142:150-159.
    • (2012) Clin Immunol , vol.142 , pp. 150-159
    • Papp, G.1    Horvath, I.F.2    Barath, S.3    Gyimesi, E.4    Vegh, J.5    Szodoray, P.6
  • 36
    • 84867890726 scopus 로고    scopus 로고
    • The effects of extracorporeal photochemotherapy on T cell activation and regulatory mechanisms in patients with systemic sclerosis
    • Papp G., Barath S., Szegedi A., Szodoray P., Zeher M. The effects of extracorporeal photochemotherapy on T cell activation and regulatory mechanisms in patients with systemic sclerosis. Clin Rheumatol 2012, 31:1293-1299.
    • (2012) Clin Rheumatol , vol.31 , pp. 1293-1299
    • Papp, G.1    Barath, S.2    Szegedi, A.3    Szodoray, P.4    Zeher, M.5
  • 37
    • 0015289868 scopus 로고
    • Mixed connective tissue disease - an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen
    • Sharp G.C., Irvin W.S., Tan E.M., Gould R.G., Holman H.R. Mixed connective tissue disease - an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen. Am J Med 1972, 52:148-159.
    • (1972) Am J Med , vol.52 , pp. 148-159
    • Sharp, G.C.1    Irvin, W.S.2    Tan, E.M.3    Gould, R.G.4    Holman, H.R.5
  • 38
    • 0002135512 scopus 로고
    • Diagnostic criteria for classification of MCTD
    • Elsevier Science Publishers BV, Amsterdam, R. Kasukawa, G.C. Sharp (Eds.)
    • Sharp G.C. Diagnostic criteria for classification of MCTD. Mixed connective tissue disease and antinuclear antibodies 1987, 23-33. Elsevier Science Publishers BV, Amsterdam. R. Kasukawa, G.C. Sharp (Eds.).
    • (1987) Mixed connective tissue disease and antinuclear antibodies , pp. 23-33
    • Sharp, G.C.1
  • 39
    • 0001793894 scopus 로고
    • Preliminary diagnostic criteria for classification of mixed connective tissue disease
    • Elsevier Science Publishers BV, Amsterdam, R. Kasukawa, G.C. Sharp (Eds.)
    • Kasukawa R., Tojo T., Miyawaki S. Preliminary diagnostic criteria for classification of mixed connective tissue disease. Mixed connective tissue disease and antinuclear antibodies 1987, 41-47. Elsevier Science Publishers BV, Amsterdam. R. Kasukawa, G.C. Sharp (Eds.).
    • (1987) Mixed connective tissue disease and antinuclear antibodies , pp. 41-47
    • Kasukawa, R.1    Tojo, T.2    Miyawaki, S.3
  • 41
    • 0031957166 scopus 로고    scopus 로고
    • Mixed connective tissue disease: to be or not to be?
    • Smolen J.S., Steiner G. Mixed connective tissue disease: to be or not to be?. Arthritis Rheum 1998, 41:768-777.
    • (1998) Arthritis Rheum , vol.41 , pp. 768-777
    • Smolen, J.S.1    Steiner, G.2
  • 45
    • 0036791870 scopus 로고    scopus 로고
    • Serum cytokine levels and type 1 and type 2 intracellular T cell cytokine profiles in mixed connective tissue disease
    • Bodolay E., Aleksza M., Antal-Szalmás P., Végh J., Szodoray P., Soltész P., et al. Serum cytokine levels and type 1 and type 2 intracellular T cell cytokine profiles in mixed connective tissue disease. J Rheumatol 2002, 29:2136-2142.
    • (2002) J Rheumatol , vol.29 , pp. 2136-2142
    • Bodolay, E.1    Aleksza, M.2    Antal-Szalmás, P.3    Végh, J.4    Szodoray, P.5    Soltész, P.6
  • 46
    • 33746796650 scopus 로고    scopus 로고
    • Regulatory T cells in peripheral blood of patients with mixed connective tissue disease
    • Baráth S., Sipka S., Aleksza M., Szegedi A., Szodoray P., Végh J., et al. Regulatory T cells in peripheral blood of patients with mixed connective tissue disease. Scand J Rheumatol 2006, 35:300-304.
    • (2006) Scand J Rheumatol , vol.35 , pp. 300-304
    • Baráth, S.1    Sipka, S.2    Aleksza, M.3    Szegedi, A.4    Szodoray, P.5    Végh, J.6
  • 47
    • 70349234677 scopus 로고    scopus 로고
    • Sensorineural hearing loss in patients with mixed connective tissue disease: immunological markers and cytokine levels
    • Hajas A., Szodoray P., Barath S., Sipka S., Rezes S., Zeher M., et al. Sensorineural hearing loss in patients with mixed connective tissue disease: immunological markers and cytokine levels. J Rheumatol 2009, 36:1930-1936.
    • (2009) J Rheumatol , vol.36 , pp. 1930-1936
    • Hajas, A.1    Szodoray, P.2    Barath, S.3    Sipka, S.4    Rezes, S.5    Zeher, M.6
  • 49
    • 16844369607 scopus 로고    scopus 로고
    • Natural regulatory T cells in infectious disease
    • Belkaid Y., Rouse B.T. Natural regulatory T cells in infectious disease. Nat Immunol 2005, 6:353-360.
    • (2005) Nat Immunol , vol.6 , pp. 353-360
    • Belkaid, Y.1    Rouse, B.T.2
  • 50
    • 44449110577 scopus 로고    scopus 로고
    • Primary immune deficiency disorders presenting as autoimmune diseases: IPEX and APECED
    • Moraes-Vasconcelos D., Costa-Carvalho B.T., Torgerson T.R., Ochs H.D. Primary immune deficiency disorders presenting as autoimmune diseases: IPEX and APECED. J Clin Immunol 2008, 28(Suppl. 1):S11-S19.
    • (2008) J Clin Immunol , vol.28 , Issue.SUPPL. 1
    • Moraes-Vasconcelos, D.1    Costa-Carvalho, B.T.2    Torgerson, T.R.3    Ochs, H.D.4
  • 51
    • 84856212497 scopus 로고    scopus 로고
    • Genetic disorders with immune dysregulation
    • Gambineri E., Torgerson T.R. Genetic disorders with immune dysregulation. Cell Mol Life Sci 2012, 69:49-58.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 49-58
    • Gambineri, E.1    Torgerson, T.R.2
  • 52
    • 84860534160 scopus 로고    scopus 로고
    • Immunodeficiency diseases with rheumatic manifestations
    • Torgerson T.R. Immunodeficiency diseases with rheumatic manifestations. Pediatr Clin North Am 2012, 59:493-507.
    • (2012) Pediatr Clin North Am , vol.59 , pp. 493-507
    • Torgerson, T.R.1
  • 53
    • 79955393382 scopus 로고    scopus 로고
    • Flow cytometric analysis of TCR Vbeta repertoire in patients with 22q11.2 deletion syndrome
    • McLean-Tooke A., Barge D., Spickett G.P., Gennery A.R. Flow cytometric analysis of TCR Vbeta repertoire in patients with 22q11.2 deletion syndrome. Scand J Immunol 2011, 73:577-585.
    • (2011) Scand J Immunol , vol.73 , pp. 577-585
    • McLean-Tooke, A.1    Barge, D.2    Spickett, G.P.3    Gennery, A.R.4
  • 54
    • 33846805925 scopus 로고    scopus 로고
    • CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like syndrome, and defective IL-10 expression from CD4 lymphocytes
    • Caudy A.A., Reddy S.T., Chatila T., Atkinson J.P., Verbsky J.W. CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like syndrome, and defective IL-10 expression from CD4 lymphocytes. J Allergy Clin Immunol 2007, 119:482-487.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 482-487
    • Caudy, A.A.1    Reddy, S.T.2    Chatila, T.3    Atkinson, J.P.4    Verbsky, J.W.5
  • 55
    • 34250687456 scopus 로고    scopus 로고
    • Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome
    • Adriani M., Aoki J., Horai R., Thornton A.M., Konno A., Kirby M., et al. Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome. Clin Immunol 2007, 124:41-48.
    • (2007) Clin Immunol , vol.124 , pp. 41-48
    • Adriani, M.1    Aoki, J.2    Horai, R.3    Thornton, A.M.4    Konno, A.5    Kirby, M.6
  • 56
    • 84874199166 scopus 로고    scopus 로고
    • The STAT5b pathway defect and autoimmunity
    • Kanai T., Jenks J., Nadeau K.C. The STAT5b pathway defect and autoimmunity. Front Immunol 2012, 3:234.
    • (2012) Front Immunol , vol.3 , pp. 234
    • Kanai, T.1    Jenks, J.2    Nadeau, K.C.3
  • 57
    • 65349173560 scopus 로고    scopus 로고
    • TH17 cells and regulatory T cells in primary immunodeficiency diseases
    • Ochs H.D., Oukka M., Torgerson T.R. TH17 cells and regulatory T cells in primary immunodeficiency diseases. J Allergy Clin Immunol 2009, 123:977-983.
    • (2009) J Allergy Clin Immunol , vol.123 , pp. 977-983
    • Ochs, H.D.1    Oukka, M.2    Torgerson, T.R.3
  • 58
    • 84864126962 scopus 로고    scopus 로고
    • Chronic mucocutaneous candidiasis caused by a gain-of-function mutation in the STAT1 DNA-binding domain
    • Takezaki S., Yamada M., Kato M., Park M.J., Maruyama K., Yamazaki Y., et al. Chronic mucocutaneous candidiasis caused by a gain-of-function mutation in the STAT1 DNA-binding domain. J Immunol 2012, 189:1521-1526.
    • (2012) J Immunol , vol.189 , pp. 1521-1526
    • Takezaki, S.1    Yamada, M.2    Kato, M.3    Park, M.J.4    Maruyama, K.5    Yamazaki, Y.6
  • 59
    • 77149124612 scopus 로고    scopus 로고
    • Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I
    • Puel A., Doffinger R., Natividad A., Chrabieh M., Barcenas-Morales G., Picard C., et al. Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I. J Exp Med 2010, 207:291-297.
    • (2010) J Exp Med , vol.207 , pp. 291-297
    • Puel, A.1    Doffinger, R.2    Natividad, A.3    Chrabieh, M.4    Barcenas-Morales, G.5    Picard, C.6
  • 60
    • 79959572627 scopus 로고    scopus 로고
    • Cutting edge: human regulatory T cells require IL-35 to mediate suppression and infectious tolerance
    • Chaturvedi V., Collison L.W., Guy C.S., Workman C.J., Vignali D.A. Cutting edge: human regulatory T cells require IL-35 to mediate suppression and infectious tolerance. J Immunol 2011, 186:6661-6666.
    • (2011) J Immunol , vol.186 , pp. 6661-6666
    • Chaturvedi, V.1    Collison, L.W.2    Guy, C.S.3    Workman, C.J.4    Vignali, D.A.5
  • 61
    • 84867574956 scopus 로고    scopus 로고
    • Cytotoxic lymphocyte microRNAs as prospective biomarkers for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
    • Brenu E.W., Ashton K.J., van Driel M., Staines D.R., Peterson D., Atkinson G.M., et al. Cytotoxic lymphocyte microRNAs as prospective biomarkers for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis. J Affect Disord 2012, 141:261-269.
    • (2012) J Affect Disord , vol.141 , pp. 261-269
    • Brenu, E.W.1    Ashton, K.J.2    van Driel, M.3    Staines, D.R.4    Peterson, D.5    Atkinson, G.M.6
  • 62
    • 84860867111 scopus 로고    scopus 로고
    • Longitudinal investigation of natural killer cells and cytokines in chronic fatigue syndrome/myalgic encephalomyelitis
    • Brenu E.W., van Driel M.L., Staines D.R., Ashton K.J., Hardcastle S.L., Keane J., et al. Longitudinal investigation of natural killer cells and cytokines in chronic fatigue syndrome/myalgic encephalomyelitis. J Transl Med 2012, 10:88.
    • (2012) J Transl Med , vol.10 , pp. 88
    • Brenu, E.W.1    van Driel, M.L.2    Staines, D.R.3    Ashton, K.J.4    Hardcastle, S.L.5    Keane, J.6
  • 63
    • 79957440333 scopus 로고    scopus 로고
    • Immunological abnormalities as potential biomarkers in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
    • Brenu E.W., van Driel M.L., Staines D.R., Ashton K.J., Ramos S.B., Keane J., et al. Immunological abnormalities as potential biomarkers in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis. J Transl Med 2011, 9:81.
    • (2011) J Transl Med , vol.9 , pp. 81
    • Brenu, E.W.1    van Driel, M.L.2    Staines, D.R.3    Ashton, K.J.4    Ramos, S.B.5    Keane, J.6
  • 64
    • 78650415467 scopus 로고    scopus 로고
    • Relationship between cytokine profiles and clinical outcomes in patients with systemic sclerosis
    • Baraut J., Michel L., Verrecchia F., Farge D. Relationship between cytokine profiles and clinical outcomes in patients with systemic sclerosis. Autoimmun Rev 2010, 10:65-73.
    • (2010) Autoimmun Rev , vol.10 , pp. 65-73
    • Baraut, J.1    Michel, L.2    Verrecchia, F.3    Farge, D.4
  • 65
    • 84866564036 scopus 로고    scopus 로고
    • Functional niche of inflamed synovium for Th17-cell expansion and activation in rheumatoid arthritis: implication to clinical therapeutics
    • Dong W., Zhu P. Functional niche of inflamed synovium for Th17-cell expansion and activation in rheumatoid arthritis: implication to clinical therapeutics. Autoimmun Rev 2012, 11:844-851.
    • (2012) Autoimmun Rev , vol.11 , pp. 844-851
    • Dong, W.1    Zhu, P.2
  • 66
    • 84865357576 scopus 로고    scopus 로고
    • Anti-cytokine vaccination: a new biotherapy of autoimmunity?
    • Semerano L., Assier E., Boissier M.C. Anti-cytokine vaccination: a new biotherapy of autoimmunity?. Autoimmun Rev 2012, 11:785-786.
    • (2012) Autoimmun Rev , vol.11 , pp. 785-786
    • Semerano, L.1    Assier, E.2    Boissier, M.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.