Greater impairment of postprandial triacylglycerol than glucose response in metabolic syndrome subjects with fasting hyperglycaemia

Metabolism: Clinical and Experimental

Volumn 62, Issue 8, 2013, Pages 1065-1069

  Jackson, Kim G ^a   Walden, Charlotte M ^b   Murray, Peter ^b   Smith, Adrian M ^b   Minihane, Anne M ^a,c   Lovegrove, Julie A ^a   Williams, Christine M ^a  

^a UNIVERSITY OF READING   (United Kingdom)

^b UNILEVER RESEARCH   (United Kingdom)

^c UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

Non esterified fatty acids; Postprandial state; Sequential test meal protocol

Indexed keywords

GLUCOSE; INSULIN; LIPID; TRIACYLGLYCEROL;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; HUMAN; HYPERGLYCEMIA; INSULIN RESPONSE; MAJOR CLINICAL STUDY; MALE; MEAL; METABOLIC SYNDROME X; POSTPRANDIAL STATE; PRIORITY JOURNAL; SEQUENTIAL ANALYSIS; TEST MEAL;

AREA UNDER THE CURVE; AUC; BMI; BODY MASS INDEX; CARDIOVASCULAR DISEASE; CVD; HDL-C; HIGH-DENSITY LIPOPROTEIN CHOLESTEROL; HOMA-IR; HOMEOSTASIS MODEL ASSESSMENT OF INSULIN RESISTANCE; IAUC; INCREMENTAL AUC; LDL-C; LOW-DENSITY LIPOPROTEIN CHOLESTEROL; MAXC; MAXIMUM CONCENTRATION; METABOLIC SYNDROME; METS; MINC; MINIMUM CONCENTRATION; NEFA; NON-ESTERIFIED FATTY ACIDS; POSTPRANDIAL STATE; SEQUENTIAL TEST MEAL PROTOCOL; TAG; TAG-RICH LIPOPROTEIN; TRIACYLGLYCEROL; TRL;

ADULT; AGED; AREA UNDER CURVE; BLOOD GLUCOSE; BLOOD PRESSURE; BODY MASS INDEX; CHOLESTEROL, HDL; CHOLESTEROL, LDL; FASTING; FATTY ACIDS, NONESTERIFIED; FEMALE; HUMANS; HYPERGLYCEMIA; INSULIN; LIPIDS; MALE; METABOLIC SYNDROME X; MIDDLE AGED; POSTPRANDIAL PERIOD; REGRESSION ANALYSIS; TRIGLYCERIDES;

EID: 84880572500     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2013.03.001     Document Type: Article

References (19)

1. J. Sundstrom, E. Vallhagen, and U. Riserus Risk associated with the metabolic syndrome versus the sum of its individual components Diabetes Care 29 2006 1673 1674
2. L. Guize, F. Thomas, and B. Pannier All-cause mortality associated with specific combinations of the metabolic syndrome according to recent definitions Diabetes Care 30 2007 2381 2387
3. Y. Hong, X. Jin, and J. Mo Metabolic syndrome, its preeminent clusters, incident coronary heart disease and all-cause mortality - results of prospective analysis for the Atherosclerosis Risk in Communities study J Intern Med 262 2007 113 122
4. H. Sone, S. Tanaka, and S. Iimuro Components of metabolic syndrome and their combinations as predictors of cardiovascular disease in Japanese patients with type 2 diabetes. Implications for improved definition. Analysis from Japan Diabetes Complications Study (JDCS) J Atheroscler Thromb 16 2009 380 387
5. O.H. Franco, J.M. Massaro, and J. Civil Trajectories of entering the metabolic syndrome: the Framingham heart study Circ 120 2009 1943 1950
6. R. Haring, H. Wallaschofski, and M. Nauck Total and cardiovascular disease mortality predicted by metabolic syndrome is inferior relative to its components Exp Clin Endocrinol Diab 118 2010 685 691
7. G. Pigna, A. Napoli, and F. Zaccagna The relationship between metabolic syndrome, its components, and the whole-body atherosclerotic burden as measured by computed tomography angiography Atherosclerosis 215 2011 417 420
8. K.G. Jackson, S.D. Poppit, and A.M. Minihane Postprandial lipaemia and cardiovascular disease risk: interrelationships between dietary, physiological and genetic determinants Atherosclerosis 220 2012 22 33
9. K.G. Jackson, C.M. Walden, and P. Murray A sequential two meal challenge reveals abnormalities in postprandial TAG but not glucose in men with increasing numbers of metabolic syndrome components Atherosclerosis 220 2012 237 243
10. K.G. Jackson, D.T. Clarke, and P. Murray Introduction to the DISRUPT postprandial database: subjects, studies and methodologies Genes Nutr 5 2009 39 48
11. D.R. Matthews, J.P. Hosker, and A.S. Rudenski Homeostasis model assessment - insulin resistance and beta-cell function from fasting plasma-glucose and insulin concentrations in man Diabetologia 28 1985 412 419
12. S.M. Grundy, J.I. Cleeman, and S.R. Daniels Diagnosis and management of the metabolic syndrome - an American Heart Association/National Heart, Lung, and Blood Institute scientific statement Circ 112 2005 2735 2752
13. K. Alberti, R.H. Eckel, and S.M. Grundy Harmonizing the metabolic syndrome a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity Circ 120 2009 1640 1645
14. G.D. Kolovou, K.K. Anagnostopoulou, and A.N. Pavlidis Metabolic syndrome and gender differences in postprandial lipaemia Eur J Cardiovasc Prev Rehabil 13 2006 661 664
15. L.M. Ntyintyane, V.R. Panz, and F.J. Raal Postprandial lipaemia, metabolic syndrome and LDL particle size in urbanised South African blacks with and without coronary artery disease QJM 101 2008 111 119
16. M. Pavlic, C. Xiao, and L. Szeto Insulin acutely inhibits intestinal lipoprotein secretion in humans in part by suppressing plasma free fatty acids Diabetes 59 2010 580 587
17. M. Greenfield, O. Kolterman, and J. Olefsky Mechanisms of hypertriglyceridaemia in diabetic patients with fasting hyperglycaemia Diabetologia 18 1980 441 446
18. C. Xiao, and G.F. Lewis Regulation of chylomicron production in humans Biochim Biophys Acta 2012 1821 736 746
19. A. Ceriello, J. Davidson, and M. Hanefeld Postprandial hyperglycaemia and cardiovascular complications of diabetes: an update Nutr Metab Cardiovasc Dis 16 2006 453 456