Postoperative residual neuromuscular blockade is associated with impaired clinical recovery

Anesthesia and Analgesia

Volumn 117, Issue 1, 2013, Pages 133-141

  Murphy, Glenn S ^a   Szokol, Joseph W ^a   Avram, Michael J ^a   Greenberg, Steven B ^a   Shear, Torin ^a   Vender, Jeffery S ^a   Gray, Jayla ^a   Landry, Elizabeth ^a  

^a NORTHSHORE UNIVERSITY HEALTHSYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ROCURONIUM;

ACCELEROMYOGRAPHY; ADULT; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HOSPITAL ADMISSION; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MUSCLE WEAKNESS; MYOGRAPHY; NEUROMUSCULAR BLOCKING; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RECOVERY ROOM;

ADULT; AGED; ANESTHESIA RECOVERY PERIOD; FEMALE; HUMANS; KINETOCARDIOGRAPHY; MALE; MIDDLE AGED; MUSCLE WEAKNESS; NEUROMUSCULAR BLOCKADE; NEUROMUSCULAR MONITORING; POSTOPERATIVE COMPLICATIONS;

EID: 84880570017     PISSN: 00032999     EISSN: 15267598     Source Type: Journal    
DOI: 10.1213/ANE.0b013e3182742e75     Document Type: Article

References (31)

1. Naguib M, Kopman AF, Ensor JE. Neuromuscular monitoring and postoperative residual curarisation: a meta-analysis. Br J Anaesth 2007;98:302-16
2. Murphy GS, Szokol JW, Marymont JH, Greenberg SB, Avram MJ, Vender JS. Residual neuromuscular blockade and critical respiratory events in the postanesthesia care unit. Anesth Analg 2008;107:130-7
3. Eikermann M, Groeben H, Hüsing J, Peters J. Accelerometry of adductor pollicis muscle predicts recovery of respiratory function from neuromuscular blockade. Anesthesiology 2003;98:1333-7
4. Eikermann M, Vogt FM, Herbstreit F, Vahid-Dastgerdi M, Zenge MO, Ochterbeck C, de Greiff A, Peters J. The predisposition to inspiratory upper airway collapse during partial neuro-muscular blockade. Am J Respir Crit Care Med 2007;175:9-15
5. Sundman E, Witt H, Olsson R, Ekberg O, Kuylenstierna R, Eriksson LI. The incidence and mechanisms of pharyngeal and upper esophageal dysfunction in partially paralyzed humans: pharyngeal videoradiography and simultaneous manometry after atracurium. Anesthesiology 2000;92:977-84
6. Berg H, Roed J, Viby-Mogensen J, Mortensen CR, Engbaek J, Skovgaard LT, Krintel JJ. Residual neuromuscular block is a risk factor for postoperative pulmonary complications: a prospective, randomised, and blinded study of postoperative pulmonary complications after atracurium, vecuronium and pancuronium. Acta Anaesthesiol Scand 1997;41:1095-103
7. Cammu G, De Witte J, De Veylder J, Byttebier G, Vandeput D, Foubert L, Vandenbroucke G, Deloof T. Postoperative residual paralysis in outpatients versus inpatients. Anesth Analg 2006;102:426-9
8. McCaul C, Tobin E, Boylan JF, McShane AJ. Atracurium is associated with postoperative residual curarization. Br J Anaesth 2002;89:766-9
9. Butterly A, Bittner EA, George E, Sandberg WS, Eikermann M, Schmidt U. Postoperative residual curarization from intermediate-acting neuromuscular blocking agents delays recovery room discharge. Br J Anaesth 2010;105:304-9
10. Murphy GS, Szokol JW, Marymont JH, Greenberg SB, Avram MJ, Vender JS, Nisman M. Intraoperative acceleromyographic monitoring reduces the risk of residual neuromuscular blockade and adverse respiratory events in the postanesthesia care unit. Anesthesiology 2008;109:389-98
11. Murphy GS, Szokol JW, Avram MJ, Greenberg SB, Marymont JH, Vender JS, Gray J, Landry E, Gupta DK. Intraoperative acceleromyography monitoring reduces symptoms of muscle weakness and improves quality of recovery in the early postoperative period. Anesthesiology 2011;115:946-54
12. Murphy GS, Szokol JW, Franklin M, Marymont JH, Avram MJ, Vender JS. Postanesthesia care unit recovery times and neuromuscular blocking drugs: a prospective study of orthopedic surgical patients randomized to receive pancuronium or rocuronium. Anesth Analg 2004;98:193-200
13. Eikermann M, Groeben H, Hüsing J, Peters J. Accelerometry of adductor pollicis muscle predicts recovery of respiratory function from neuromuscular blockade. Anesthesiology 2003;98:1333-7
14. Miettinen OS, Nurminen M. Comparative analysis of two rates. Stat Med 1985;4:213-26
15. Newcombe RG. Interval estimation for the difference between independent proportions: comparison of eleven methods. Stat Med 1998;17:873-90
16. D'Agostino RB, Belanger A, D'Agostino RB Jr. A suggestion for using powerful and informative tests of normality. Am Stat 1990;44:316-21
17. Monahan JF. Algorithm 616: fast computation of the Hodges-Lehmann location estimator. ACM Trans Math Software 1984;10:265-70
18. Skovlund E, Fenstad GU. Should we always choose a nonpara-metric test when comparing two apparently nonnormal distributions? J Clin Epidemiol 2001;54:86-92
19. Kopman AF. Neuromuscular monitoring: old issues, new controversies. J Crit Care 2009;24:11-20
20. Eikermann M, Gerwig M, Hasselmann C, Fiedler G, Peters J. Impaired neuromuscular transmission after recovery of the train-of-four ratio. Acta Anaesthesiol Scand 2007;51:226-34
21. Cahill F, Kalmar JM, Pretorius T, Gardiner PF, Giesbrecht GG. Whole-body hypothermia has central and peripheral infuences on elbow fexor performance. Exp Physiol 2011;96:528-38
22. Winkelman C. The role of infammation in ICU-acquired weakness. Crit Care 2010;14:186
23. Kopman AF, Yee PS, Neuman GG. Relationship of the train-of-four fade ratio to clinical signs and symptoms of residual paralysis in awake volunteers. Anesthesiology 1997;86:765-71
24. Murphy GS, Szokol JW, Marymont JH, Vender JS, Avram MJ, Rosengart TK, Alwawi EA. Recovery of neuromuscular function after cardiac surgery: pancuronium versus rocuronium. Anesth Analg 2003;96:1301-7
25. Heier T, Caldwell JE, Feiner JR, Liu L, Ward T, Wright PM. Relationship between normalized adductor pollicis train-of-four ratio and manifestations of residual neuromuscular block: a study using acceleromyography during near steady-state concentrations of mivacurium. Anesthesiology 2010;113:825-32
26. Brull SJ, Murphy GS. Residual neuromuscular block: lessons unlearned. Part II Methods to reduce the risk of residual weakness. Anesth Analg 2010;111:129-40
27. Grayling M, Sweeney BP. Recovery from neuromuscular blockade: a survey of practice. Anaesthesia 2007;62:806-9
28. Claudius C, Skovgaard LT, Viby-Mogensen J. Is the performance of acceleromyography improved with preload and normalization? A comparison with mechanomyography. Anesthesiology 2009;110:1261-70
29. Samet A, Capron F, Alla F, Meistelman C, Fuchs-Buder T. Single acceleromyographic train-of-four, 100-Hertz tetanus or double-burst stimulation: which test performs better to detect residual paralysis? Anesthesiology 2005;102:51-6
30. Kopman AF, Klewicka MM, Neuman GG. The relationship between acceleromyographic train-of-four fade and single twitch depression. Anesthesiology 2002;96:583-7
31. Baillard C, Bourdiau S, Le Toumelin P, Ait Kaci F, Riou B, Cupa M, Samama CM. Assessing residual neuromuscular blockade using acceleromyography can be deceptive in postoperative awake patients. Anesth Analg 2004;98:854-7