-
1
-
-
1642323740
-
Protein kinase inhibitors: Insights into drug design from structure
-
Noble, M.E., Endicott, J.A. and Johnson, L.N. (2004) Protein kinase inhibitors: insights into drug design from structure. Science 303, 1800-1805
-
(2004)
Science
, vol.303
, pp. 1800-1805
-
-
Noble, M.E.1
Endicott, J.A.2
Johnson, L.N.3
-
2
-
-
79953308071
-
Catalytic control in the EGF receptor and its connection to general kinase regulatory mechanisms
-
Jura, N., Zhang, X., Endres, N.F., Seeliger, M.A., Schindler, T. and Kuriyan, J. (2011) Catalytic control in the EGF receptor and its connection to general kinase regulatory mechanisms. Mol. Cell 42, 9-22
-
(2011)
Mol. Cell
, vol.42
, pp. 9-22
-
-
Jura, N.1
Zhang, X.2
Endres, N.F.3
Seeliger, M.A.4
Schindler, T.5
Kuriyan, J.6
-
3
-
-
84866729606
-
Assembly of allosteric macromolecular switches: Lessons from PKA
-
Taylor, S.S., Ilouz, R., Zhang, P. and Kornev, A.P. (2012) Assembly of allosteric macromolecular switches: lessons from PKA. Nat. Rev. Mol. Cell Biol. 13, 646-658
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 646-658
-
-
Taylor, S.S.1
Ilouz, R.2
Zhang, P.3
Kornev, A.P.4
-
4
-
-
75349112388
-
Recent developments in cyclin-dependent kinase biochemical and structural studies
-
Echalier, A., Endicott, J.A. and Noble, M.E. (2010) Recent developments in cyclin-dependent kinase biochemical and structural studies. Biochim. Biophys. Acta 1804, 511-519
-
(2010)
Biochim. Biophys. Acta
, vol.1804
, pp. 511-519
-
-
Echalier, A.1
Endicott, J.A.2
Noble, M.E.3
-
5
-
-
0031466305
-
Cyclin-dependent kinases: Engines, clocks, and microprocessors
-
Morgan, D.O. (1997) Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu. Rev. Cell Dev. Biol. 13, 261-291
-
(1997)
Annu. Rev. Cell Dev. Biol.
, vol.13
, pp. 261-291
-
-
Morgan, D.O.1
-
7
-
-
8644219655
-
Living with or without cyclins and cyclin-dependent kinases
-
Sherr, C.J. and Roberts, J.M. (2004) Living with or without cyclins and cyclin-dependent kinases. Genes Dev. 18, 2699-2711
-
(2004)
Genes Dev.
, vol.18
, pp. 2699-2711
-
-
Sherr, C.J.1
Roberts, J.M.2
-
8
-
-
84871963013
-
P21WAF1 and tumourigenesis: 20 years after
-
Warfel, N.A. and El-Deiry, W.S. (2013) p21WAF1 and tumourigenesis: 20 years after. Curr. Opin. Oncol. 25, 52-58
-
(2013)
Curr. Opin. Oncol.
, vol.25
, pp. 52-58
-
-
Warfel, N.A.1
El-Deiry, W.S.2
-
9
-
-
81055138204
-
Quality control in the initiation of eukaryotic DNA replication
-
Diffley, J.F. (2011) Quality control in the initiation of eukaryotic DNA replication. Philos. Trans. R. Soc. London Ser. B 366, 3545-3553
-
(2011)
Philos. Trans. R. Soc. London Ser. B
, vol.366
, pp. 3545-3553
-
-
Diffley, J.F.1
-
10
-
-
29244468847
-
Secrets of a double agent: CDK7 in cell-cycle control and transcription
-
Fisher, R.P. (2005) Secrets of a double agent: CDK7 in cell-cycle control and transcription. J. Cell Sci. 118, 5171-5180
-
(2005)
J. Cell Sci.
, vol.118
, pp. 5171-5180
-
-
Fisher, R.P.1
-
11
-
-
79953162883
-
Function and regulation of the Mediator complex
-
Conaway, R.C. and Conaway, J.W. (2011) Function and regulation of the Mediator complex. Curr. Opin. Genet. Dev. 21, 225-230
-
(2011)
Curr. Opin. Genet. Dev.
, vol.21
, pp. 225-230
-
-
Conaway, R.C.1
Conaway, J.W.2
-
12
-
-
79960377780
-
A history of TFIIH: Two decades of molecular biology on a pivotal transcription/repair factor
-
Egly, J.M. and Coin, F. (2011) A history of TFIIH: two decades of molecular biology on a pivotal transcription/repair factor. DNA Repair 10, 714-721
-
(2011)
DNA Repair
, vol.10
, pp. 714-721
-
-
Egly, J.M.1
Coin, F.2
-
13
-
-
84869095110
-
Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II
-
Larochelle, S., Amat, R., Glover-Cutter, K., Sanso, M., Zhang, C., Allen, J.J., Shokat, K.M., Bentley, D.L. and Fisher, R.P. (2012) Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II. Nat. Struct. Mol. Biol. 19, 1108-1115
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 1108-1115
-
-
Larochelle, S.1
Amat, R.2
Glover-Cutter, K.3
Sanso, M.4
Zhang, C.5
Allen, J.J.6
Shokat, K.M.7
Bentley, D.L.8
Fisher, R.P.9
-
14
-
-
0037424470
-
CDK11 complexes promote pre-mRNA splicing
-
Hu, D., Mayeda, A., Trembley, J.H., Lahti, J.M. and Kidd, V.J. (2003) CDK11 complexes promote pre-mRNA splicing. J. Biol. Chem. 278, 8623-8629
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8623-8629
-
-
Hu, D.1
Mayeda, A.2
Trembley, J.H.3
Lahti, J.M.4
Kidd, V.J.5
-
15
-
-
84859791205
-
Cyclin K goes with Cdk12 and Cdk13
-
Kohoutek, J. and Blazek, D. (2012) Cyclin K goes with Cdk12 and Cdk13. Cell Div. 7, 12
-
(2012)
Cell Div.
, vol.7
, pp. 12
-
-
Kohoutek, J.1
Blazek, D.2
-
16
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science 298, 1912-1934
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
17
-
-
71049169616
-
Cyclin-dependent kinases: A family portrait
-
Malumbres, M., Harlow, E., Hunt, T., Hunter, T., Lahti, J.M., Manning, G., Morgan, D.O., Tsai, L.H. and Wolgemuth, D.J. (2009) Cyclin-dependent kinases: a family portrait. Nat. Cell Biol. 11, 1275-1276
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1275-1276
-
-
Malumbres, M.1
Harlow, E.2
Hunt, T.3
Hunter, T.4
Lahti, J.M.5
Manning, G.6
Morgan, D.O.7
Tsai, L.H.8
Wolgemuth, D.J.9
-
18
-
-
0026721068
-
A family of human cdc2-related protein kinases
-
Meyerson, M., Enders, G.H., Wu, C.L., Su, L.K., Gorka, C., Nelson, C., Harlow, E. and Tsai, L.H. (1992) A family of human cdc2-related protein kinases. EMBO J. 11, 2909-2917
-
(1992)
EMBO J.
, vol.11
, pp. 2909-2917
-
-
Meyerson, M.1
Enders, G.H.2
Wu, C.L.3
Su, L.K.4
Gorka, C.5
Nelson, C.6
Harlow, E.7
Tsai, L.H.8
-
19
-
-
70350782350
-
PCTK proteins: The forgotten brain kinases?
-
Cole, A.R. (2009) PCTK proteins: the forgotten brain kinases? Neurosignals 17, 288-297
-
(2009)
Neurosignals
, vol.17
, pp. 288-297
-
-
Cole, A.R.1
-
20
-
-
0036711806
-
Regulation of the CDK-related protein kinase PCTAIRE-1 and its possible role in neurite outgrowth in Neuro-2A cells
-
Graeser, R., Gannon, J., Poon, R.Y., Dubois, T., Aitken, A. and Hunt, T. (2002) Regulation of the CDK-related protein kinase PCTAIRE-1 and its possible role in neurite outgrowth in Neuro-2A cells. J. Cell Sci. 115, 3479-3490
-
(2002)
J. Cell Sci.
, vol.115
, pp. 3479-3490
-
-
Graeser, R.1
Gannon, J.2
Poon, R.Y.3
Dubois, T.4
Aitken, A.5
Hunt, T.6
-
21
-
-
84856767106
-
Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin y and is essential for spermatogenesis
-
Mikolcevic, P., Sigl, R., Rauch, V., Hess, M.W., Pfaller, K., Barisic, M., Pelliniemi, L.J., Boesl, M. and Geley, S. (2012) Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis. Mol. Cell. Biol. 32, 868-879
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 868-879
-
-
Mikolcevic, P.1
Sigl, R.2
Rauch, V.3
Hess, M.W.4
Pfaller, K.5
Barisic, M.6
Pelliniemi, L.J.7
Boesl, M.8
Geley, S.9
-
22
-
-
26244442308
-
PCTAIRE protein kinases interact directly with the COPII complex and modulate secretory cargo transport
-
Palmer, K.J., Konkel, J.E. and Stephens, D.J. (2005) PCTAIRE protein kinases interact directly with the COPII complex and modulate secretory cargo transport. J. Cell Sci. 118, 3839-3847
-
(2005)
J. Cell Sci.
, vol.118
, pp. 3839-3847
-
-
Palmer, K.J.1
Konkel, J.E.2
Stephens, D.J.3
-
23
-
-
33744545575
-
Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: Implications in the regulation of its hexamerization and exocytosis
-
Liu, Y., Cheng, K., Gong, K., Fu, A.K. and Ip, N.Y. (2006) Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: implications in the regulation of its hexamerization and exocytosis. J. Biol. Chem. 281, 9852-9858
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 9852-9858
-
-
Liu, Y.1
Cheng, K.2
Gong, K.3
Fu, A.K.4
Ip, N.Y.5
-
24
-
-
77953266051
-
Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components
-
Ou, C.Y., Poon, V.Y., Maeder, C.I., Watanabe, S., Lehrman, E.K., Fu, A.K., Park, M., Fu, W.Y., Jorgensen, E.M., Ip, N.Y. and Shen, K. (2010) Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components. Cell 141, 846-858
-
(2010)
Cell
, vol.141
, pp. 846-858
-
-
Ou, C.Y.1
Poon, V.Y.2
Maeder, C.I.3
Watanabe, S.4
Lehrman, E.K.5
Fu, A.K.6
Park, M.7
Fu, W.Y.8
Jorgensen, E.M.9
Ip, N.Y.10
Shen, K.11
-
25
-
-
0032190168
-
Characterization of brain PCTAIRE-1 kinase immunoreactivity and its interactions with p11 and 14-3-3 proteins
-
Le Bouffant, F., Capdevielle, J., Guillemot, J.C. and Sladeczek, F. (1998) Characterization of brain PCTAIRE-1 kinase immunoreactivity and its interactions with p11 and 14-3-3 proteins. Eur. J. Biochem. 257, 112-120
-
(1998)
Eur. J. Biochem.
, vol.257
, pp. 112-120
-
-
Le Bouffant, F.1
Capdevielle, J.2
Guillemot, J.C.3
Sladeczek, F.4
-
26
-
-
84865339164
-
Analysis of substrate specificity and cyclin y binding of PCTAIRE-1 kinase
-
Shehata, S.N., Hunter, R.W., Ohta, E., Peggie, M.W., Lou, H.J., Sicheri, F., Zeqiraj, E., Turk, B.E. and Sakamoto, K. (2012) Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase. Cell. Signalling 24, 2085-2094
-
(2012)
Cell. Signalling
, vol.24
, pp. 2085-2094
-
-
Shehata, S.N.1
Hunter, R.W.2
Ohta, E.3
Peggie, M.W.4
Lou, H.J.5
Sicheri, F.6
Zeqiraj, E.7
Turk, B.E.8
Sakamoto, K.9
-
27
-
-
80053070661
-
Involvement of cyclin-dependent kinase-like 2 in cognitive function required for contextual and spatial learning in mice
-
Gomi, H., Sassa, T., Thompson, R.F. and Itohara, S. (2010) Involvement of cyclin-dependent kinase-like 2 in cognitive function required for contextual and spatial learning in mice. Front. Behav. Neurosci. 4, 17
-
(2010)
Front. Behav. Neurosci.
, vol.4
, pp. 17
-
-
Gomi, H.1
Sassa, T.2
Thompson, R.F.3
Itohara, S.4
-
28
-
-
43049089394
-
Inactivation of the CDKL3 gene at 5q31. 1 by a balanced t(X;5) translocation associated with nonspecific mild mental retardation
-
Dubos, A., Pannetier, S. and Hanauer, A. (2008) Inactivation of the CDKL3 gene at 5q31.1 by a balanced t(X;5) translocation associated with nonspecific mild mental retardation. Am. J. Med. Genet., Part A 146, 1267-1279
-
(2008)
Am. J. Med. Genet., Part A
, vol.146
, pp. 1267-1279
-
-
Dubos, A.1
Pannetier, S.2
Hanauer, A.3
-
29
-
-
84863737648
-
What we know and would like to know about CDKL5 and its involvement in epileptic encephalopathy
-
Kilstrup-Nielsen, C., Rusconi, L., La Montanara, P., Ciceri, D., Bergo, A., Bedogni, F. and Landsberger, N. (2012) What we know and would like to know about CDKL5 and its involvement in epileptic encephalopathy. Neural Plast. 2012, 728267
-
(2012)
Neural Plast.
, vol.2012
, pp. 728267
-
-
Kilstrup-Nielsen, C.1
Rusconi, L.2
La Montanara, P.3
Ciceri, D.4
Bergo, A.5
Bedogni, F.6
Landsberger, N.7
-
30
-
-
84874104782
-
The CDKL5 disorder is an independent clinical entity associated with early-onset encephalopathy
-
Fehr, S., Wilson, M., Downs, J., Williams, S., Murgia, A., Sartori, S., Vecchi, M., Ho, G., Polli, R., Psoni, S. et al. (2013) The CDKL5 disorder is an independent clinical entity associated with early-onset encephalopathy. Eur. J. Hum. Genet. 21, 266-273
-
(2013)
Eur. J. Hum. Genet.
, vol.21
, pp. 266-273
-
-
Fehr, S.1
Wilson, M.2
Downs, J.3
Williams, S.4
Murgia, A.5
Sartori, S.6
Vecchi, M.7
Ho, G.8
Polli, R.9
Psoni, S.10
-
31
-
-
0027182223
-
Crystal structure of cyclin-dependent kinase 2
-
De Bondt, H.L., Rosenblatt, J., Jancarik, J., Jones, H.D., Morgan, D.O. and Kim, S.H. (1993) Crystal structure of cyclin-dependent kinase 2. Nature 363, 595-602
-
(1993)
Nature
, vol.363
, pp. 595-602
-
-
De Bondt, H.L.1
Rosenblatt, J.2
Jancarik, J.3
Jones, H.D.4
Morgan, D.O.5
Kim, S.H.6
-
32
-
-
55749102720
-
A helix scaffold for the assembly of active protein kinases
-
Kornev, A.P., Taylor, S.S. and Ten Eyck, L.F. (2008) A helix scaffold for the assembly of active protein kinases. Proc. Natl. Acad. Sci. U.S.A. 105, 14377-14382
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 14377-14382
-
-
Kornev, A.P.1
Taylor, S.S.2
Ten Eyck, L.F.3
-
33
-
-
75349091799
-
Defining the conserved internal architecture of a protein kinase
-
Kornev, A.P. and Taylor, S.S. (2010) Defining the conserved internal architecture of a protein kinase. Biochim. Biophys. Acta 1804, 440-444
-
(2010)
Biochim. Biophys. Acta
, vol.1804
, pp. 440-444
-
-
Kornev, A.P.1
Taylor, S.S.2
-
34
-
-
84861859600
-
The structural basis for control of eukaryotic protein kinases
-
Endicott, J.A., Noble, M.E. and Johnson, L.N. (2012) The structural basis for control of eukaryotic protein kinases. Annu. Rev. Biochem. 81, 587-613
-
(2012)
Annu. Rev. Biochem.
, vol.81
, pp. 587-613
-
-
Endicott, J.A.1
Noble, M.E.2
Johnson, L.N.3
-
35
-
-
0030962139
-
The Cdk-like protein PCTAIRE-1 from mouse brain associates with p11 and 14-3-3 proteins
-
Sladeczek, F., Camonis, J.H., Burnol, A.F. and Le Bouffant, F. (1997) The Cdk-like protein PCTAIRE-1 from mouse brain associates with p11 and 14-3-3 proteins. Mol. Gen. Genet. 254, 571-577
-
(1997)
Mol. Gen. Genet.
, vol.254
, pp. 571-577
-
-
Sladeczek, F.1
Camonis, J.H.2
Burnol, A.F.3
Le Bouffant, F.4
-
36
-
-
0037199958
-
Pctaire1 interacts with p35 and is a novel substrate for Cdk5/p35
-
Cheng, K., Li, Z., Fu, W.Y., Wang, J.H., Fu, A.K. and Ip, N.Y. (2002) Pctaire1 interacts with p35 and is a novel substrate for Cdk5/p35. J. Biol. Chem. 277, 31988-31993
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 31988-31993
-
-
Cheng, K.1
Li, Z.2
Fu, W.Y.3
Wang, J.H.4
Fu, A.K.5
Ip, N.Y.6
-
37
-
-
34547151676
-
Functional characterization of human PFTK1 as a cyclin-dependent kinase
-
Shu, F., Lv, S., Qin, Y., Ma, X., Wang, X., Peng, X., Luo, Y., Xu, B.E., Sun, X. and Wu, J. (2007) Functional characterization of human PFTK1 as a cyclin-dependent kinase. Proc. Natl. Acad. Sci. U.S.A. 104, 9248-9253
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 9248-9253
-
-
Shu, F.1
Lv, S.2
Qin, Y.3
Ma, X.4
Wang, X.5
Peng, X.6
Luo, Y.7
Xu, B.E.8
Sun, X.9
Wu, J.10
-
38
-
-
34248597065
-
Differential regulation and properties of MAPKs
-
Raman, M., Chen, W. and Cobb, M.H. (2007) Differential regulation and properties of MAPKs. Oncogene 26, 3100-3112
-
(2007)
Oncogene
, vol.26
, pp. 3100-3112
-
-
Raman, M.1
Chen, W.2
Cobb, M.H.3
-
39
-
-
0029767016
-
Structural basis of cyclin-dependent kinase activation by phosphorylation
-
Russo, A.A., Jeffrey, P.D. and Pavletich, N.P. (1996) Structural basis of cyclin-dependent kinase activation by phosphorylation. Nat. Struct. Biol. 3, 696-700
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 696-700
-
-
Russo, A.A.1
Jeffrey, P.D.2
Pavletich, N.P.3
-
40
-
-
0030866897
-
Activation mechanism of the MAP kinase ERK2 by dual phosphorylation
-
Canagarajah, B.J., Khokhlatchev, A., Cobb, M.H. and Goldsmith, E.J. (1997) Activation mechanism of the MAP kinase ERK2 by dual phosphorylation. Cell 90, 859-869
-
(1997)
Cell
, vol.90
, pp. 859-869
-
-
Canagarajah, B.J.1
Khokhlatchev, A.2
Cobb, M.H.3
Goldsmith, E.J.4
-
41
-
-
33947256308
-
Docking interactions in protein kinase and phosphatase networks
-
Remenyi, A., Good, M.C. and Lim, W.A. (2006) Docking interactions in protein kinase and phosphatase networks. Curr. Opin. Struct. Biol. 16, 676-685
-
(2006)
Curr. Opin. Struct. Biol.
, vol.16
, pp. 676-685
-
-
Remenyi, A.1
Good, M.C.2
Lim, W.A.3
-
42
-
-
33751261134
-
Mechanisms of MAPK signalling specificity
-
Bardwell, L. (2006) Mechanisms of MAPK signalling specificity. Biochem. Soc. Trans. 34, 837-841
-
(2006)
Biochem. Soc. Trans.
, vol.34
, pp. 837-841
-
-
Bardwell, L.1
-
43
-
-
84875465105
-
Protein-peptide complex crystallization: A case study on the ERK2 mitogen-activated protein kinase
-
Gogl, G., Toro, I. and Remenyi, A. (2013) Protein-peptide complex crystallization: a case study on the ERK2 mitogen-activated protein kinase. Acta Crystallogr., Sect. D: Biol. Crystallogr. 69, 486-489
-
(2013)
Acta Crystallogr., Sect. D: Biol. Crystallogr.
, vol.69
, pp. 486-489
-
-
Gogl, G.1
Toro, I.2
Remenyi, A.3
-
44
-
-
0029029617
-
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex
-
Jeffrey, P.D., Russo, A.A., Polyak, K., Gibbs, E., Hurwitz, J., Massague, J. and Pavletich, N.P. (1995) Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex. Nature 376, 313-320
-
(1995)
Nature
, vol.376
, pp. 313-320
-
-
Jeffrey, P.D.1
Russo, A.A.2
Polyak, K.3
Gibbs, E.4
Hurwitz, J.5
Massague, J.6
Pavletich, N.P.7
-
45
-
-
0033224309
-
The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases
-
Brown, N.R., Noble, M.E., Endicott, J.A. and Johnson, L.N. (1999) The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases. Nat. Cell Biol. 1, 438-443
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 438-443
-
-
Brown, N.R.1
Noble, M.E.2
Endicott, J.A.3
Johnson, L.N.4
-
46
-
-
0034786018
-
Structure and regulation of the CDK5-p25nck5a complex
-
Tarricone, C., Dhavan, R., Peng, J., Areces, L.B., Tsai, L.H. and Musacchio, A. (2001) Structure and regulation of the CDK5-p25nck5a complex. Mol. Cell 8, 657-669
-
(2001)
Mol. Cell
, vol.8
, pp. 657-669
-
-
Tarricone, C.1
Dhavan, R.2
Peng, J.3
Areces, L.B.4
Tsai, L.H.5
Musacchio, A.6
-
47
-
-
63149148791
-
Crystal structure of human CDK4 in complex with a D-type cyclin
-
Day, P.J., Cleasby, A., Tickle, I.J., O'Reilly, M., Coyle, J.E., Holding, F.P., McMenamin, R.L., Yon, J., Chopra, R., Lengauer, C. and Jhoti, H. (2009) Crystal structure of human CDK4 in complex with a D-type cyclin. Proc. Natl. Acad. Sci. U.S.A. 106, 4166-4170
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 4166-4170
-
-
Day, P.J.1
Cleasby, A.2
Tickle, I.J.3
O'Reilly, M.4
Coyle, J.E.5
Holding, F.P.6
McMenamin, R.L.7
Yon, J.8
Chopra, R.9
Lengauer, C.10
Jhoti, H.11
-
48
-
-
63149111417
-
The structure of CDK4/cyclin D3 has implications for models of CDK activation
-
Takaki, T., Echalier, A., Brown, N.R., Hunt, T., Endicott, J.A. and Noble, M.E. (2009) The structure of CDK4/cyclin D3 has implications for models of CDK activation. Proc. Natl. Acad. Sci. U.S.A. 106, 4171-4176
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 4171-4176
-
-
Takaki, T.1
Echalier, A.2
Brown, N.R.3
Hunt, T.4
Endicott, J.A.5
Noble, M.E.6
-
49
-
-
46949093191
-
The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation
-
Baumli, S., Lolli, G., Lowe, E.D., Troiani, S., Rusconi, L., Bullock, A.N., Debreczeni, J.E., Knapp, S. and Johnson, L.N. (2008) The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation. EMBO J. 27, 1907-1918
-
(2008)
EMBO J.
, vol.27
, pp. 1907-1918
-
-
Baumli, S.1
Lolli, G.2
Lowe, E.D.3
Troiani, S.4
Rusconi, L.5
Bullock, A.N.6
Debreczeni, J.E.7
Knapp, S.8
Johnson, L.N.9
-
50
-
-
84867395695
-
The CDK9 tail determines the reaction pathway of positive transcription elongation factor b
-
Baumli, S., Hole, A.J., Wang, L.Z., Noble, M.E. and Endicott, J.A. (2012) The CDK9 tail determines the reaction pathway of positive transcription elongation factor b. Structure 20, 1788-1795
-
(2012)
Structure
, vol.20
, pp. 1788-1795
-
-
Baumli, S.1
Hole, A.J.2
Wang, L.Z.3
Noble, M.E.4
Endicott, J.A.5
-
51
-
-
0033817555
-
CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 Tat-P-TEFb complex to TAR RNA
-
Garber, M.E., Mayall, T.P., Suess, E.M., Meisenhelder, J., Thompson, N.E. and Jones, K.A. (2000) CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 Tat-P-TEFb complex to TAR RNA. Mol. Cell. Biol. 20, 6958-6969
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 6958-6969
-
-
Garber, M.E.1
Mayall, T.P.2
Suess, E.M.3
Meisenhelder, J.4
Thompson, N.E.5
Jones, K.A.6
-
52
-
-
80052034056
-
The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket binder
-
Schneider, E.V., Bottcher, J., Blaesse, M., Neumann, L., Huber, R. and Maskos, K. (2011) The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket binder. J. Mol. Biol. 412, 251-266
-
(2011)
J. Mol. Biol.
, vol.412
, pp. 251-266
-
-
Schneider, E.V.1
Bottcher, J.2
Blaesse, M.3
Neumann, L.4
Huber, R.5
Maskos, K.6
-
53
-
-
0029665852
-
Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex
-
Russo, A.A., Jeffrey, P.D., Patten, A.K., Massague, J. and Pavletich, N.P. (1996) Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex. Nature 382, 325-331
-
(1996)
Nature
, vol.382
, pp. 325-331
-
-
Russo, A.A.1
Jeffrey, P.D.2
Patten, A.K.3
Massague, J.4
Pavletich, N.P.5
-
54
-
-
33747359918
-
The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition
-
Cheng, K.Y., Noble, M.E., Skamnaki, V., Brown, N.R., Lowe, E.D., Kontogiannis, L., Shen, K., Cole, P.A., Siligardi, G. and Johnson, L.N. (2006) The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition. J. Biol. Chem. 281, 23167-23179
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 23167-23179
-
-
Cheng, K.Y.1
Noble, M.E.2
Skamnaki, V.3
Brown, N.R.4
Lowe, E.D.5
Kontogiannis, L.6
Shen, K.7
Cole, P.A.8
Siligardi, G.9
Johnson, L.N.10
-
55
-
-
0030580320
-
The crystal structure of human cyclin H
-
Andersen, G., Poterszman, A., Egly, J.M., Moras, D. and Thierry, J.C. (1996) The crystal structure of human cyclin H. FEBS Lett. 397, 65-69
-
(1996)
FEBS Lett.
, vol.397
, pp. 65-69
-
-
Andersen, G.1
Poterszman, A.2
Egly, J.M.3
Moras, D.4
Thierry, J.C.5
-
56
-
-
0001212842
-
Three-dimensional structure of human cyclin H, a positive regulator of the CDK-activating kinase
-
Kim, K.K., Chamberlin, H.M., Morgan, D.O. and Kim, S.H. (1996) Three-dimensional structure of human cyclin H, a positive regulator of the CDK-activating kinase. Nat. Struct. Biol. 3, 849-855
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 849-855
-
-
Kim, K.K.1
Chamberlin, H.M.2
Morgan, D.O.3
Kim, S.H.4
-
57
-
-
77953431827
-
Crystal structure of HIV-1 Tat complexed with human P-TEFb
-
Tahirov, T.H., Babayeva, N.D., Varzavand, K., Cooper, J.J., Sedore, S.C. and Price, D.H. (2010) Crystal structure of HIV-1 Tat complexed with human P-TEFb. Nature 465, 747-751
-
(2010)
Nature
, vol.465
, pp. 747-751
-
-
Tahirov, T.H.1
Babayeva, N.D.2
Varzavand, K.3
Cooper, J.J.4
Sedore, S.C.5
Price, D.H.6
-
58
-
-
84879054579
-
The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat
-
Schulze-Gahmen, U., Upton, H., Birnberg, A., Bao, K., Chou, S., Krogan, N.J., Zhou, Q. and Alber, T. (2013) The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat. eLife 2, e00327
-
(2013)
ELife
, vol.2
-
-
Schulze-Gahmen, U.1
Upton, H.2
Birnberg, A.3
Bao, K.4
Chou, S.5
Krogan, N.J.6
Zhou, Q.7
Alber, T.8
-
59
-
-
84864020768
-
The super elongation complex family of RNA polymerase II elongation factors: Gene target specificity and transcriptional output
-
Luo, Z., Lin, C., Guest, E., Garrett, A.S., Mohaghegh, N., Swanson, S., Marshall, S., Florens, L., Washburn, M.P. and Shilatifard, A. (2012) The super elongation complex family of RNA polymerase II elongation factors: gene target specificity and transcriptional output. Mol. Cell. Biol. 32, 2608-2617
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 2608-2617
-
-
Luo, Z.1
Lin, C.2
Guest, E.3
Garrett, A.S.4
Mohaghegh, N.5
Swanson, S.6
Marshall, S.7
Florens, L.8
Washburn, M.P.9
Shilatifard, A.10
-
60
-
-
21944438071
-
Structure of the Mediator subunit cyclin C and its implications for CDK8 function
-
Hoeppner, S., Baumli, S. and Cramer, P. (2005) Structure of the Mediator subunit cyclin C and its implications for CDK8 function. J. Mol. Biol. 350, 833-842
-
(2005)
J. Mol. Biol.
, vol.350
, pp. 833-842
-
-
Hoeppner, S.1
Baumli, S.2
Cramer, P.3
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