-
1
-
-
0022634839
-
Clinical implications of tumor-cell heterogeneity
-
Schnipper L. Clinical implications of tumor-cell heterogeneity. N Engl J Med 1986; 314: 1423-32.
-
(1986)
N Engl J Med
, vol.314
, pp. 1423-1432
-
-
Schnipper, L.1
-
2
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB et al. Molecular portraits of human breast tumours. Nature 2000; 406: 747-52.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
-
3
-
-
0038210242
-
Aromatase inhibitors in breast cancer
-
Smith IE, Dowsett M. Aromatase inhibitors in breast cancer. N Engl J Med 2003; 348: 2431-42.
-
(2003)
N Engl J Med
, vol.348
, pp. 2431-2442
-
-
Smith, I.E.1
Dowsett, M.2
-
4
-
-
26844559765
-
Trastuzumab in the treatment of breast cancer
-
Hortobagyi GN. Trastuzumab in the treatment of breast cancer. N Engl J Med 2005; 353: 1734-6.
-
(2005)
N Engl J Med
, vol.353
, pp. 1734-1736
-
-
Hortobagyi, G.N.1
-
5
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger M, Rowan AJ, Horswell S et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 2012; 366: 883-92.
-
(2012)
N Engl J Med
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
-
6
-
-
0018569942
-
A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate
-
Goldie JH, Coldman AJ. A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate. Cancer Treat Rep 1979; 63: 1727-33.
-
(1979)
Cancer Treat Rep
, vol.63
, pp. 1727-1733
-
-
Goldie, J.H.1
Coldman, A.J.2
-
7
-
-
0022360120
-
Implications of kinetic heterogeneity in clinical oncology
-
Norton L. Implications of kinetic heterogeneity in clinical oncology. Semin Oncol 1985; 12: 231-49.
-
(1985)
Semin Oncol
, vol.12
, pp. 231-249
-
-
Norton, L.1
-
8
-
-
78651156947
-
Experimental evaluation of potential anticancer agents. XII. On the criteria and kinetics associated with curability of experimental leukemia
-
Skipper HE, Schabel FM, Wilcox WS. Experimental evaluation of potential anticancer agents. XII. On the criteria and kinetics associated with curability of experimental leukemia. Cancer Chemother Rep 1964; 35: 1-111.
-
(1964)
Cancer Chemother Rep
, vol.35
, pp. 1-111
-
-
Skipper, H.E.1
Schabel, F.M.2
Wilcox, W.S.3
-
9
-
-
19344364880
-
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials
-
Early Breast Cancer Trialists' Collaborative Group.
-
Early Breast Cancer Trialists' Collaborative Group. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005; 365: 1687-717.
-
(2005)
Lancet
, vol.365
, pp. 1687-1717
-
-
-
10
-
-
84856636292
-
Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100,000 women in 123 randomized trials
-
Early Breast Cancer Trialists Collaborative Group T.
-
Early Breast Cancer Trialists Collaborative Group T. Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100, 000 women in 123 randomized trials. Lancet 2012; 379: 432-44.
-
(2012)
Lancet
, vol.379
, pp. 432-444
-
-
-
11
-
-
0020701032
-
Multiple estrogen receptor assays in human breast cancer
-
Hull DF 3rd, Clark GM, Osborne CK, Chamness GC, Knight WA 3rd, McGuire WL. Multiple estrogen receptor assays in human breast cancer. Cancer Res 1983; 43: 413-6.
-
(1983)
Cancer Res
, vol.43
, pp. 413-416
-
-
Hull III, D.F.1
Clark, G.M.2
Osborne, C.K.3
Chamness, G.C.4
Knight III, W.A.5
McGuire, W.L.6
-
12
-
-
84864085607
-
Clinically used breast cancer markers such as estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 are unstable throughout tumor progression
-
Lindstrom LS, Karlsson E, Wilking UM et al. Clinically used breast cancer markers such as estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 are unstable throughout tumor progression. J Clin Oncol 2012; 30: 2601-8.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2601-2608
-
-
Lindstrom, L.S.1
Karlsson, E.2
Wilking, U.M.3
-
13
-
-
0018907029
-
Changes in multiple or sequential estrogen receptor determinations in breast cancer
-
Allegra JC, Barlock A, Huff KK, Lippman ME. Changes in multiple or sequential estrogen receptor determinations in breast cancer. Cancer 1980; 45: 792-4.
-
(1980)
Cancer
, vol.45
, pp. 792-794
-
-
Allegra, J.C.1
Barlock, A.2
Huff, K.K.3
Lippman, M.E.4
-
14
-
-
42249099793
-
Heterogeneity of breast cancer metastases: comparison of therapeutic target expression and promoter methylation between primary tumors and their multifocal metastases
-
Wu JM, Fackler MJ, Halushka MK et al. Heterogeneity of breast cancer metastases: comparison of therapeutic target expression and promoter methylation between primary tumors and their multifocal metastases. Clin Cancer Res 2008; 14: 1938-46.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1938-1946
-
-
Wu, J.M.1
Fackler, M.J.2
Halushka, M.K.3
-
15
-
-
48949119465
-
Cancer stem cell heterogeneity in hereditary breast cancer
-
Wicha MS. Cancer stem cell heterogeneity in hereditary breast cancer. Breast Cancer Res 2008; 10: 105.
-
(2008)
Breast Cancer Res
, vol.10
, pp. 105
-
-
Wicha, M.S.1
-
16
-
-
0034991321
-
Evaluation of HER2, p53, bcl-2, topoisomerase II-alpha, heat shock proteins 27 and 70 in primary breast cancer and metastatic ipsilateral axillary lymph nodes
-
Cardoso F, Di Leo A, Larsimont D et al. Evaluation of HER2, p53, bcl-2, topoisomerase II-alpha, heat shock proteins 27 and 70 in primary breast cancer and metastatic ipsilateral axillary lymph nodes. Ann Oncol 2001; 12: 615-20.
-
(2001)
Ann Oncol
, vol.12
, pp. 615-620
-
-
Cardoso, F.1
Di Leo, A.2
Larsimont, D.3
-
17
-
-
0034654130
-
Association of angiogenesis in lymph node metastases with outcome of breast cancer
-
Guidi AJ, Berry DA, Broadwater G et al. Association of angiogenesis in lymph node metastases with outcome of breast cancer. J Natl Cancer Inst 2000; 92: 486-92.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 486-492
-
-
Guidi, A.J.1
Berry, D.A.2
Broadwater, G.3
-
18
-
-
84863078767
-
Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer
-
Baselga J, Campone M, Piccart M et al. Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer. N Engl J Med 2012; 366: 520-9.
-
(2012)
N Engl J Med
, vol.366
, pp. 520-529
-
-
Baselga, J.1
Campone, M.2
Piccart, M.3
-
19
-
-
21844457575
-
Treatment of metastatic breast cancer
-
Harris J, Lippman M, Morrow M, Osborne CK, eds. Philadelphia: Lippincott Williams & Wilkins
-
Ellis M, Hayes DF, Lippman ME. Treatment of metastatic breast cancer. In: Harris J, Lippman M, Morrow M, Osborne CK, eds. Diseases of the Breast. Philadelphia: Lippincott Williams & Wilkins, 2004; 1101-62.
-
(2004)
Diseases of the Breast
, pp. 1101-1162
-
-
Ellis, M.1
Hayes, D.F.2
Lippman, M.E.3
-
20
-
-
0014200880
-
Endocrine therapy of breast cancer
-
Kennedy BJ. Endocrine therapy of breast cancer. J Am Med Assoc 1967; 200: 971-2.
-
(1967)
J Am Med Assoc
, vol.200
, pp. 971-972
-
-
Kennedy, B.J.1
-
21
-
-
0019941487
-
Biological diversity in metastatic neoplasms: origins and implications
-
Fidler IJ, Hart IR. Biological diversity in metastatic neoplasms: origins and implications. Science 1982; 217: 998-1003.
-
(1982)
Science
, vol.217
, pp. 998-1003
-
-
Fidler, I.J.1
Hart, I.R.2
-
22
-
-
84861527388
-
The genomic and transcriptomic architecture of 2,000 breast tumors reveals novel subgroups
-
Curtis C, Shah S, Chin S-F et al. The genomic and transcriptomic architecture of 2, 000 breast tumors reveals novel subgroups. Nature 2012; 486: 346-52.
-
(2012)
Nature
, vol.486
, pp. 346-352
-
-
Curtis, C.1
Shah, S.2
Chin, S.-F.3
-
23
-
-
84862526929
-
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
-
Shah SP, Roth A, Goya R et al. The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature 2012; 486: 395-9.
-
(2012)
Nature
, vol.486
, pp. 395-399
-
-
Shah, S.P.1
Roth, A.2
Goya, R.3
-
24
-
-
84862584058
-
Whole-genome analysis informs breast cancer response to aromatase inhibition
-
Ellis MJ, Ding L, Shen D et al. Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature 2012; 486: 353-60.
-
(2012)
Nature
, vol.486
, pp. 353-360
-
-
Ellis, M.J.1
Ding, L.2
Shen, D.3
-
25
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
Ding L, Ellis MJ, Li S et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 2010; 464: 999-1005.
-
(2010)
Nature
, vol.464
, pp. 999-1005
-
-
Ding, L.1
Ellis, M.J.2
Li, S.3
-
26
-
-
37249069903
-
Reversal of the estrogen receptor negative phenotype in breast cancer and restoration of antiestrogen response
-
Bayliss J, Hilger A, Vishnu P, Diehl K, El-Ashry D. Reversal of the estrogen receptor negative phenotype in breast cancer and restoration of antiestrogen response. Clin Cancer Res 2007; 13: 7029-36.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 7029-7036
-
-
Bayliss, J.1
Hilger, A.2
Vishnu, P.3
Diehl, K.4
El-Ashry, D.5
-
27
-
-
25844468319
-
Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer
-
Gee JM, Robertson JF, Gutteridge E et al. Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer. Endocr Relat Cancer 2005; 12(Suppl. 1): S99-111.
-
(2005)
Endocr Relat Cancer
, vol.12
, Issue.SUPPL. 1
-
-
Gee, J.M.1
Robertson, J.F.2
Gutteridge, E.3
-
28
-
-
79955004388
-
Acquired endocrine resistance in breast cancer: implications for tumour metastasis
-
Hayes E, Nicholson RI, Hiscox S. Acquired endocrine resistance in breast cancer: implications for tumour metastasis. Front Biosci 2011; 16: 838-48.
-
(2011)
Front Biosci
, vol.16
, pp. 838-848
-
-
Hayes, E.1
Nicholson, R.I.2
Hiscox, S.3
-
29
-
-
84866563517
-
The importance of HER2 signaling in the tumor-initiating cell population in aromatase inhibitor-resistant breast cancer
-
Gilani RA, Kazi AA, Shah P et al. The importance of HER2 signaling in the tumor-initiating cell population in aromatase inhibitor-resistant breast cancer. Breast Cancer Res Treat 2012; 135: 681-92.
-
(2012)
Breast Cancer Res Treat
, vol.135
, pp. 681-692
-
-
Gilani, R.A.1
Kazi, A.A.2
Shah, P.3
-
30
-
-
0000110505
-
A case of cancer in which cells similar to those in the tumours were seen in the blood after death
-
Ashworth TR. A case of cancer in which cells similar to those in the tumours were seen in the blood after death. Aust Med J 1869; 14: 146-9.
-
(1869)
Aust Med J
, vol.14
, pp. 146-149
-
-
Ashworth, T.R.1
-
32
-
-
78649696669
-
Use of circulating tumor cells in peripheral blood of breast cancer patients before and after adjuvant chemotehapy to predict increased risk for relapse: the SUCCESS trial
-
Abstract #1003).
-
Rack B, Schindlbeck C, Andergassen U et al. Use of circulating tumor cells in peripheral blood of breast cancer patients before and after adjuvant chemotehapy to predict increased risk for relapse: the SUCCESS trial. Proc Am Soc Clin Oncol 2010; 28: 114s (Abstract #1003).
-
(2010)
Proc Am Soc Clin Oncol
, vol.28
-
-
Rack, B.1
Schindlbeck, C.2
Andergassen, U.3
-
33
-
-
84863105627
-
Circulating tumour cells in non-metastatic breast cancer: a prospective study
-
Lucci A, Hall CS, Lodhi AK et al. Circulating tumour cells in non-metastatic breast cancer: a prospective study. Lancet Oncol 2012; 13: 688-95.
-
(2012)
Lancet Oncol
, vol.13
, pp. 688-695
-
-
Lucci, A.1
Hall, C.S.2
Lodhi, A.K.3
-
34
-
-
79955847549
-
Prognostic role of circulating tumor cells in the peripheral blood of primary breast cancer patients
-
abstract S6-5).
-
Rack B, Schindlbeck C, Andergassen U et al. Prognostic role of circulating tumor cells in the peripheral blood of primary breast cancer patients. Cancer Res 2010; 24(suppl): 93 (abstract S6-5).
-
(2010)
Cancer Res
, vol.24
, Issue.SUPPL.
, pp. 93
-
-
Rack, B.1
Schindlbeck, C.2
Andergassen, U.3
-
35
-
-
67449164275
-
Re: anti-epithelial cell adhesion molecule antibodies and the detection of circulating normal-like breast tumor cells
-
author reply 6-7.
-
Hayes DF, Cristofanilli M. Re: anti-epithelial cell adhesion molecule antibodies and the detection of circulating normal-like breast tumor cells. J Natl Cancer Inst 2009; 101: 894-5 author reply 6-7.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 894-895
-
-
Hayes, D.F.1
Cristofanilli, M.2
-
37
-
-
4143099370
-
Circulating tumor cells in metastatic breast cancer - toward individualized treatment?
-
Braun S, Marth C. Circulating tumor cells in metastatic breast cancer - toward individualized treatment? N Engl J Med 2004; 351: 824-6.
-
(2004)
N Engl J Med
, vol.351
, pp. 824-826
-
-
Braun, S.1
Marth, C.2
-
38
-
-
19944426264
-
Circulating tumor cells in patients with breast cancer dormancy
-
Meng S, Tripathy D, Frenkel EP et al. Circulating tumor cells in patients with breast cancer dormancy. Clin Cancer Res 2004; 10: 8152-62.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8152-8162
-
-
Meng, S.1
Tripathy, D.2
Frenkel, E.P.3
-
39
-
-
4143134311
-
Isolated tumor cells in bone marrow three years after diagnosis in disease-free breast cancer patients predict unfavorable clinical outcome
-
Wiedswang G, Borgen E, Karesen R et al. Isolated tumor cells in bone marrow three years after diagnosis in disease-free breast cancer patients predict unfavorable clinical outcome. Clin Cancer Res 2004; 10: 5342-8.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5342-5348
-
-
Wiedswang, G.1
Borgen, E.2
Karesen, R.3
-
40
-
-
79955016306
-
Circulating tumor cells: not all detected cells are bad and not all bad cells are detected
-
Wicha MS, Hayes DF. Circulating tumor cells: not all detected cells are bad and not all bad cells are detected. J Clin Oncol 2011; 29: 1508-11.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1508-1511
-
-
Wicha, M.S.1
Hayes, D.F.2
-
41
-
-
67651005404
-
EMT: when epithelial cells decide to become mesenchymal-like cells
-
Kalluri R. EMT: when epithelial cells decide to become mesenchymal-like cells. J Clin Invest 2009; 119: 1417-9.
-
(2009)
J Clin Invest
, vol.119
, pp. 1417-1419
-
-
Kalluri, R.1
-
42
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest 2009; 119: 1420-8.
-
(2009)
J Clin Invest
, vol.119
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
44
-
-
59449107785
-
Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1
-
Neubauer H, Clare SE, Wozny W et al. Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1. Breast Cancer Res 2008; 10: R85.
-
(2008)
Breast Cancer Res
, vol.10
-
-
Neubauer, H.1
Clare, S.E.2
Wozny, W.3
-
45
-
-
59449092063
-
ERalpha-status of disseminated tumour cells in bone marrow of primary breast cancer patients
-
Fehm T, Krawczyk N, Solomayer EF et al. ERalpha-status of disseminated tumour cells in bone marrow of primary breast cancer patients. Breast Cancer Res 2008; 10: R76.
-
(2008)
Breast Cancer Res
, vol.10
-
-
Fehm, T.1
Krawczyk, N.2
Solomayer, E.F.3
-
46
-
-
40449098857
-
Determination of HER2 status using both serum HER2 levels and circulating tumor cells in patients with recurrent breast cancer whose primary tumor was HER2 negative or of unknown HER2 status
-
Fehm T, Becker S, Duerr-Stoerzer S et al. Determination of HER2 status using both serum HER2 levels and circulating tumor cells in patients with recurrent breast cancer whose primary tumor was HER2 negative or of unknown HER2 status. Breast Cancer Res 2007; 9: R74.
-
(2007)
Breast Cancer Res
, vol.9
-
-
Fehm, T.1
Becker, S.2
Duerr-Stoerzer, S.3
-
47
-
-
79959269553
-
Circulating tumor cells as biomarkers in prostate cancer
-
Danila DC, Fleisher M, Scher HI. Circulating tumor cells as biomarkers in prostate cancer. Clin Cancer Res 2011; 17: 3903-12.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 3903-3912
-
-
Danila, D.C.1
Fleisher, M.2
Scher, H.I.3
-
48
-
-
84863800280
-
A novel platform for detection of CK+ and CK- CTCs
-
Pecot CV, Bischoff FZ, Mayer JA et al. A novel platform for detection of CK+ and CK- CTCs. Cancer Discov 2011; 1: 580-6.
-
(2011)
Cancer Discov
, vol.1
, pp. 580-586
-
-
Pecot, C.V.1
Bischoff, F.Z.2
Mayer, J.A.3
-
49
-
-
84860601923
-
Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines
-
Powell AA, Talasaz AH, Zhang H et al. Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines. PLoS ONE 2012; 7: e33788.
-
(2012)
PLoS ONE
, vol.7
-
-
Powell, A.A.1
Talasaz, A.H.2
Zhang, H.3
-
50
-
-
47949114668
-
Detection of mutations in EGFR in circulating lung-cancer cells
-
Maheswaran S, Sequist LV, Nagrath S et al. Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med 2008; 359: 366-77.
-
(2008)
N Engl J Med
, vol.359
, pp. 366-377
-
-
Maheswaran, S.1
Sequist, L.V.2
Nagrath, S.3
-
51
-
-
84863984494
-
Final results of a multicenter phase II clinical trial evaluating the activity of single-agent lapatinib in patients with HER2-negative metastatic breast cancer and HER2-positive circulating tumor cells. A proof-of-concept study
-
Pestrin M, Bessi S, Puglisi F et al. Final results of a multicenter phase II clinical trial evaluating the activity of single-agent lapatinib in patients with HER2-negative metastatic breast cancer and HER2-positive circulating tumor cells. A proof-of-concept study. Breast Cancer Res Treat 2012; 134: 283-9.
-
(2012)
Breast Cancer Res Treat
, vol.134
, pp. 283-289
-
-
Pestrin, M.1
Bessi, S.2
Puglisi, F.3
-
52
-
-
84856406031
-
Biomarkers in the management and treatment of men with metastatic castration-resistant prostate cancer
-
Armstrong AJ, Eisenberger MA, Halabi S et al. Biomarkers in the management and treatment of men with metastatic castration-resistant prostate cancer. Eur Urol 2012; 61: 549-59.
-
(2012)
Eur Urol
, vol.61
, pp. 549-559
-
-
Armstrong, A.J.1
Eisenberger, M.A.2
Halabi, S.3
-
53
-
-
0036834995
-
Monitoring expression of HER-2 on circulating epithelial cells in patients with advanced breast cancer
-
Hayes DF, Walker TM, Singh B et al. Monitoring expression of HER-2 on circulating epithelial cells in patients with advanced breast cancer. Int J Oncol 2002; 21: 1111-7.
-
(2002)
Int J Oncol
, vol.21
, pp. 1111-1117
-
-
Hayes, D.F.1
Walker, T.M.2
Singh, B.3
|