Severe eosinophilic pneumonia presenting during gemcitabine adjuvant chemotherapy

World Journal of Surgical Oncology

Volumn 11, Issue , 2013, Pages

  Yakabe, Tomomi ^a,b   Kitahara, Kenji ^b   Komiya, Kazutoshi ^b   Sueoka Aragane, Naoko ^b   Kimura, Shinya ^b   Sugioka, Takashi ^a   Noshiro, Hirokazu ^b  

^a SAGA UNIVERSITY   (Japan)

^b SAGA UNIVERSITY   (Japan)

Author keywords

Acute lung injury; Adjuvant chemotherapy; Adverse event; Eosinophilic pneumonia; Gemcitabine; Pancreatic cancer; Pulmonary toxicity

Indexed keywords

BETA GLUCAN; GEMCITABINE; LACTATE DEHYDROGENASE; METHYLPREDNISOLONE; SIVELESTAT;

ACUTE LUNG INJURY; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANEMIA; ANTIBIOTIC THERAPY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; BLOOD GAS ANALYSIS; CANCER ADJUVANT THERAPY; CANCER SURGERY; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CREATININE BLOOD LEVEL; CYTOMEGALOVIRUS; DIARRHEA; DRUG WITHDRAWAL; DYSPNEA; EOSINOPHIL COUNT; FATIGUE; HUMAN; HYPOALBUMINEMIA; HYPOXEMIA; INFECTION; LACTATE DEHYDROGENASE BLOOD LEVEL; LOEFFLER PNEUMONIA; LUNG LAVAGE; MALAISE; MALE; MULTIPLE CYCLE TREATMENT; NEUTROPHIL COUNT; PANCREAS CANCER; PANCREATICODUODENECTOMY; PLEURA EFFUSION; PNEUMONIA; SIDE EFFECT; STEROID THERAPY; THROMBOCYTE COUNT; TREATMENT WITHDRAWAL; VOMITING;

AGED; ANTIMETABOLITES, ANTINEOPLASTIC; DEOXYCYTIDINE; HUMANS; MALE; PANCREATIC NEOPLASMS; PROGNOSIS; PULMONARY EOSINOPHILIA; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84880376381     PISSN: None     EISSN: 14777819     Source Type: Journal    
DOI: 10.1186/1477-7819-11-167     Document Type: Article

References (14)

1. Abbruzzese JL. Adjuvant therapy for surgically resected pancreatic adenocarcinoma. JAMA 2008, 299:1066-1067. 10.1001/jama.299.9.1066, 18319419.
2. Hilbig A, Oettle H. Adjuvant therapy of pancreatic cancer. Expert Rev Anticancer Ther 2010, 10:485-491. 10.1586/era.10.27, 20397913.
3. Artinyan A, Anaya DA, McKenzie S, Ellenhorn JDI, Kim J. Neoadjuvant therapy is associated with improved survival in resectable pancreatic adenocarcinoma. Cancer 2011, 117:2044-2049. 10.1002/cncr.25763, 21523715.
4. O'Reilly EM. Adjuvant therapy for pancreas adenocarcinoma: where are we going?. Expert Rev Anticancer Ther 2011, 11:173-177. 10.1586/era.10.232, 21342036.
5. Ueno H, Kosuge T, Matsuyama Y, Yamamoto J, Nakao A, Egawa S, Doi R, Monden M, Hatori T, Tanaka M, Shimada M, Kanemitsu K. A randomised phase III trial comparing gemcitabine with surgery-only in patients with resected pancreatic cancer: Japanese Study Group of Adjuvant Therapy for Pancreatic Cancer. Br J Cancer 2009, 101:908-915. 10.1038/sj.bjc.6605256, 2743365, 19690548.
6. Barlési F, Villani P, Doddoli C, Gimenez C, Kleisbauer J-P. Gemcitabine-induced severe pulmonary toxicity. Fundam Clin Pharmacol 2004, 18:85-91. 10.1046/j.0767-3981.2003.00206.x, 14748759.
7. Boiselle PM, Morrin MM, Huberman MS. Gemcitabine pulmonary toxicity: CT features. J Comput Assist Tomogr 2000, 24:977-980. 10.1097/00004728-200011000-00027, 11105721.
8. Gupta N, Ahmed I, Steinberg H, Patel D, Nissel-Horowitz S, Mehrotra B. Gemcitabine-induced pulmonary toxicity: case report and review of the literature. Am J Clin Oncol 2002, 25:96-100. 10.1097/00000421-200202000-00021, 11823707.
9. Kim YH, Mishima M, Yoshizawa A. Gemcitabine-induced acute eosinophilic pneumonia. J Thorac Oncol 2010, 5:1308-1309. 10.1097/JTO.0b013e3181e3a303, 20661093.
10. Galvão FH, Pestana JO, Capelozzi VL. Fatal gemcitabine-induced pulmonary toxicity in metastatic gallbladder adenocarcinoma. Cancer Chemother Pharmacol 2010, 65:607-10. 10.1007/s00280-009-1167-6, 2797411, 19904536.
11. Johkoh T, Muller NL, Akira M, Ichikado K, Suga M, Ando M, Yoshinaga T, Kiyama T, Mihara N, Honda O, Tomiyama N, Nakamura H. Eosinophilic lung diseases: diagnostic accuracy of thin-section CT in 111 patients. Radiology 2000, 216:773-780.
12. Allen J. Acute eosinophilic pneumonia. Semin Respir Crit Care Med 2006, 27:142-147. 10.1055/s-2006-939517, 16612765.
13. Hagio T, Matsumoto S, Nakao S, Abiru T, Ohno H, Kawabata K. Elastase inhibition reduced death associated with acid aspiration-induced lung injury in hamsters. Eur J Pharmacol 2004, 488:173-180. 10.1016/j.ejphar.2004.01.037, 15044049.
14. Higenbottam T, Kuwano K, Nemery B, Fujita Y. Understanding the mechanisms of drug-associated interstitial lung disease. Br J Cancer 2004, 91:S31-S37. 2750813, 15340376.