-
1
-
-
0033677088
-
The proinflammatory mediator macrophage migration inhibitory factor induces glucose catabolism in muscle
-
Benigni F, Atsumi T, Calandra T, Metz C, Echtenacher B, Peng T, Bucala R. The proinflammatory mediator macrophage migration inhibitory factor induces glucose catabolism in muscle. J Clin Invest. 2000;106:1291-1300.
-
(2000)
J Clin Invest.
, vol.106
, pp. 1291-1300
-
-
Benigni, F.1
Atsumi, T.2
Calandra, T.3
Metz, C.4
Echtenacher, B.5
Peng, T.6
Bucala, R.7
-
2
-
-
38449097890
-
The proinflammatory cytokine macrophage migration inhibitory factor regulates glucose metabolism during systemic inflammation
-
Atsumi T, Cho YR, Leng L, McDonald C, Yu T, Danton C, Hong EG, Mitchell RA, Metz C, Niwa H, Takeuchi J, Onodera S, Umino T, Yoshioka N, Koike T, Kim JK, Bucala R. The proinflammatory cytokine macrophage migration inhibitory factor regulates glucose metabolism during systemic inflammation. J Immunol. 2007;179:5399-5406.
-
(2007)
J Immunol.
, vol.179
, pp. 5399-5406
-
-
Atsumi, T.1
Cho, Y.R.2
Leng, L.3
McDonald, C.4
Yu, T.5
Danton, C.6
Hong, E.G.7
Mitchell, R.A.8
Metz, C.9
Niwa, H.10
Takeuchi, J.11
Onodera, S.12
Umino, T.13
Yoshioka, N.14
Koike, T.15
Kim, J.K.16
Bucala, R.17
-
3
-
-
67949111187
-
MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease
-
Verschuren L, Kooistra T, Bernhagen J, Voshol PJ, Ouwens DM, van Erk M, de Vries-van der Weij J, Leng L, van Bockel JH, van Dijk KW, Fingerle-Rowson G, Bucala R, Kleemann R. MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease. Circ Res. 2009;105:99-107.
-
(2009)
Circ Res.
, vol.105
, pp. 99-107
-
-
Verschuren, L.1
Kooistra, T.2
Bernhagen, J.3
Voshol, P.J.4
Ouwens, D.M.5
Van Erk, M.6
De Vries-Van Der, W.J.7
Leng, L.8
Van Bockel, J.H.9
Van Dijk, K.W.10
Fingerle-Rowson, G.11
Bucala, R.12
Kleemann, R.13
-
4
-
-
77955613355
-
Macrophage migration inhibitory factor deficiency leads to age-dependent impairment of glucose homeostasis in mice
-
Serre-Beinier V, Toso C, Morel P, Gonelle-Gispert C, Veyrat-Durebex C, Rohner-Jeanrenaud F, Calandra T, Roger T, James RW, Montet X, Bühler L, Bosco D, Berney T. Macrophage migration inhibitory factor deficiency leads to age-dependent impairment of glucose homeostasis in mice. J Endocrinol. 2010;206:297-306.
-
(2010)
J Endocrinol.
, vol.206
, pp. 297-306
-
-
Serre-Beinier, V.1
Toso, C.2
Morel, P.3
Gonelle-Gispert, C.4
Veyrat-Durebex, C.5
Rohner-Jeanrenaud, F.6
Calandra, T.7
Roger, T.8
James, R.W.9
Montet, X.10
Bühler, L.11
Bosco, D.12
Berney, T.13
-
5
-
-
38749137749
-
Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart
-
Miller EJ, Li J, Leng L, McDonald C, Atsumi T, Bucala R, Young LH. Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature. 2008;451:578-582.
-
(2008)
Nature.
, vol.451
, pp. 578-582
-
-
Miller, E.J.1
Li, J.2
Leng, L.3
McDonald, C.4
Atsumi, T.5
Bucala, R.6
Young, L.H.7
-
6
-
-
77954959087
-
Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart
-
Ma H, Wang J, Thomas DP, Tong C, Leng L, Wang W, Merk M, Zierow S, Bernhagen J, Ren J, Bucala R, Li J. Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart. Circulation. 2010;122:282-292.
-
(2010)
Circulation.
, vol.122
, pp. 282-292
-
-
Ma, H.1
Wang, J.2
Thomas, D.P.3
Tong, C.4
Leng, L.5
Wang, W.6
Merk, M.7
Zierow, S.8
Bernhagen, J.9
Ren, J.10
Bucala, R.11
Li, J.12
-
7
-
-
0035491442
-
Elevation of plasma level of macrophage migration inhibitory factor in patients with acute myocardial infarction
-
Yu CM, Lau CP, Lai KW, Huang XR, Chen WH, Lan HY. Elevation of plasma level of macrophage migration inhibitory factor in patients with acute myocardial infarction. Am J Cardiol. 2001;88:774-777.
-
(2001)
Am J Cardiol.
, vol.88
, pp. 774-777
-
-
Yu, C.M.1
Lau, C.P.2
Lai, K.W.3
Huang, X.R.4
Chen, W.H.5
Lan, H.Y.6
-
8
-
-
0037081712
-
Elevation of plasma levels of macrophage migration inhibitory factor in patients with acute myocardial infarction
-
Takahashi M, Nishihira J, Katsuki T, Kobayashi E, Ikeda U, Shimada K. Elevation of plasma levels of macrophage migration inhibitory factor in patients with acute myocardial infarction. Am J Cardiol. 2002;89:248-249.
-
(2002)
Am J Cardiol.
, vol.89
, pp. 248-249
-
-
Takahashi, M.1
Nishihira, J.2
Katsuki, T.3
Kobayashi, E.4
Ikeda, U.5
Shimada, K.6
-
9
-
-
12444285441
-
MIF signal transduction initiated by binding to CD74
-
Leng L, Metz CN, Fang Y, Xu J, Donnelly S, Baugh J, Delohery T, Chen Y, Mitchell RA, Bucala R. MIF signal transduction initiated by binding to CD74. J Exp Med. 2003;197:1467-1476.
-
(2003)
J Exp Med.
, vol.197
, pp. 1467-1476
-
-
Leng, L.1
Metz, C.N.2
Fang, Y.3
Xu, J.4
Donnelly, S.5
Baugh, J.6
Delohery, T.7
Chen, Y.8
Mitchell, R.A.9
Bucala, R.10
-
10
-
-
33749508911
-
CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex
-
Shi X, Leng L, Wang T, Wang W, Du X, Li J, McDonald C, Chen Z, Murphy JW, Lolis E, Noble P, Knudson W, Bucala R. CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex. Immunity. 2006;25:595-606.
-
(2006)
Immunity.
, vol.25
, pp. 595-606
-
-
Shi, X.1
Leng, L.2
Wang, T.3
Wang, W.4
Du, X.5
Li, J.6
McDonald, C.7
Chen, Z.8
Murphy, J.W.9
Lolis, E.10
Noble, P.11
Knudson, W.12
Bucala, R.13
-
11
-
-
63049135766
-
A tautomerasenull macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulation
-
Fingerle-Rowson G, Kaleswarapu DR, Schlander C, Kabgani N, Brocks T, Reinart N, Busch R, Schütz A, Lue H, Du X, Liu A, Xiong H, Chen Y, Nemajerova A, Hallek M, Bernhagen J, Leng L, Bucala R. A tautomerasenull macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulation. Mol Cell Biol. 2009;29:1922-1932.
-
(2009)
Mol Cell Biol.
, vol.29
, pp. 1922-1932
-
-
Fingerle-Rowson, G.1
Kaleswarapu, D.R.2
Schlander, C.3
Kabgani, N.4
Brocks, T.5
Reinart, N.6
Busch, R.7
Schütz, A.8
Lue, H.9
Du, X.10
Liu, A.11
Xiong, H.12
Chen, Y.13
Nemajerova, A.14
Hallek, M.15
Bernhagen, J.16
Leng, L.17
Bucala, R.18
-
12
-
-
0036259530
-
Macrophage migration inhibitory factor and the discovery of tautomerase inhibitors
-
Orita M, Yamamoto S, Katayama N, Fujita S. Macrophage migration inhibitory factor and the discovery of tautomerase inhibitors. Curr Pharm Des. 2002;8:1297-1317.
-
(2002)
Curr Pharm Des.
, vol.8
, pp. 1297-1317
-
-
Orita, M.1
Yamamoto, S.2
Katayama, N.3
Fujita, S.4
-
13
-
-
60549083542
-
Discovery of human macrophage migration inhibitory factor (MIF)-CD74 antagonists via virtual screening
-
Cournia Z, Leng L, Gandavadi S, Du X, Bucala R, Jorgensen WL. Discovery of human macrophage migration inhibitory factor (MIF)-CD74 antagonists via virtual screening. J Med Chem. 2009;52:416-424.
-
(2009)
J Med Chem.
, vol.52
, pp. 416-424
-
-
Cournia, Z.1
Leng, L.2
Gandavadi, S.3
Du, X.4
Bucala, R.5
Jorgensen, W.L.6
-
14
-
-
70350062352
-
A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor
-
Ouertatani-Sakouhi H, El-Turk F, Fauvet B, Roger T, Le Roy D, Karpinar DP, Leng L, Bucala R, Zweckstetter M, Calandra T, Lashuel HA. A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor. Biochemistry. 2009;48:9858-9870.
-
(2009)
Biochemistry.
, vol.48
, pp. 9858-9870
-
-
Ouertatani-Sakouhi, H.1
El-Turk, F.2
Fauvet, B.3
Roger, T.4
Le Roy, D.5
Karpinar, D.P.6
Leng, L.7
Bucala, R.8
Zweckstetter, M.9
Calandra, T.10
Lashuel, H.A.11
-
15
-
-
0037067777
-
The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agents
-
Lubetsky JB, Dios A, Han J, Aljabari B, Ruzsicska B, Mitchell R, Lolis E, Al-Abed Y. The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agents. J Biol Chem. 2002;277:24976-24982.
-
(2002)
J Biol Chem.
, vol.277
, pp. 24976-24982
-
-
Lubetsky, J.B.1
Dios, A.2
Han, J.3
Aljabari, B.4
Ruzsicska, B.5
Mitchell, R.6
Lolis, E.7
Al-Abed, Y.8
-
16
-
-
78149279659
-
Receptor agonists of macrophage migration inhibitory factor
-
Jorgensen WL, Gandavadi S, Du X, Hare AA, Trofimov A, Leng L, Bucala R. Receptor agonists of macrophage migration inhibitory factor. Bioorg Med Chem Lett. 2010;20:7033-7036.
-
(2010)
Bioorg Med Chem Lett.
, vol.20
, pp. 7033-7036
-
-
Jorgensen, W.L.1
Gandavadi, S.2
Du, X.3
Hare, A.A.4
Trofimov, A.5
Leng, L.6
Bucala, R.7
-
17
-
-
0027997701
-
Purification, bioactivity, and secondary structure analysis of mouse and human macrophage migration inhibitory factor (MIF)
-
Bernhagen J, Mitchell RA, Calandra T, Voelter W, Cerami A, Bucala R. Purification, bioactivity, and secondary structure analysis of mouse and human macrophage migration inhibitory factor (MIF). Biochemistry. 1994;33:14144-14155.
-
(1994)
Biochemistry.
, vol.33
, pp. 14144-14155
-
-
Bernhagen, J.1
Mitchell, R.A.2
Calandra, T.3
Voelter, W.4
Cerami, A.5
Bucala, R.6
-
18
-
-
79959817748
-
Activated protein C protects against myocardial ischemic/reperfusion injury through AMP-activated protein kinase signaling
-
Wang J, Yang L, Rezaie AR, Li J. Activated protein C protects against myocardial ischemic/reperfusion injury through AMP-activated protein kinase signaling. J Thromb Haemost. 2011;9:1308-1317.
-
(2011)
J Thromb Haemost.
, vol.9
, pp. 1308-1317
-
-
Wang, J.1
Yang, L.2
Rezaie, A.R.3
Li, J.4
-
19
-
-
77957595054
-
Optimization of N-benzyl-benzoxazol-2-ones as receptor antagonists of macrophage migration inhibitory factor (MIF)
-
Hare AA, Leng L, Gandavadi S, Du X, Cournia Z, Bucala R, Jorgensen WL. Optimization of N-benzyl-benzoxazol-2-ones as receptor antagonists of macrophage migration inhibitory factor (MIF). Bioorg Med Chem Lett. 2010;20:5811-5814.
-
(2010)
Bioorg Med Chem Lett.
, vol.20
, pp. 5811-5814
-
-
Hare, A.A.1
Leng, L.2
Gandavadi, S.3
Du, X.4
Cournia, Z.5
Bucala, R.6
Jorgensen, W.L.7
-
20
-
-
79251539843
-
A small-molecule macrophage migration inhibitory factor antagonist protects against glomerulonephritis in lupus-prone NZB/NZW F1 and MRL/lpr mice
-
Leng L, Chen L, Fan J, Greven D, Arjona A, Du X, Austin D, Kashgarian M, Yin Z, Huang XR, Lan HY, Lolis E, Nikolic-Paterson D, Bucala R. A small-molecule macrophage migration inhibitory factor antagonist protects against glomerulonephritis in lupus-prone NZB/NZW F1 and MRL/lpr mice. J Immunol. 2011;186:527-538.
-
(2011)
J Immunol.
, vol.186
, pp. 527-538
-
-
Leng, L.1
Chen, L.2
Fan, J.3
Greven, D.4
Arjona, A.5
Du, X.6
Austin, D.7
Kashgarian, M.8
Yin, Z.9
Huang, X.R.10
Lan, H.Y.11
Lolis, E.12
Nikolic-Paterson, D.13
Bucala, R.14
-
21
-
-
70349305528
-
Deficiency in TLR4 signal transduction ameliorates cardiac injury and cardiomyocyte contractile dysfunction during ischemia
-
Zhao P, Wang J, He L, Ma H, Zhang X, Zhu X, Dolence EK, Ren J, Li J. Deficiency in TLR4 signal transduction ameliorates cardiac injury and cardiomyocyte contractile dysfunction during ischemia. J Cell Mol Med. 2009;13(8A):1513-1525.
-
(2009)
J Cell Mol Med.
, vol.13
, Issue.8 A
, pp. 1513-1525
-
-
Zhao, P.1
Wang, J.2
He, L.3
Ma, H.4
Zhang, X.5
Zhu, X.6
Dolence, E.K.7
Ren, J.8
Li, J.9
-
22
-
-
78149279712
-
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
-
Russell RR 3rd, Li J, Coven DL, Pypaert M, Zechner C, Palmeri M, Giordano FJ, Mu J, Birnbaum MJ, Young LH. AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. J Clin Invest. 2004;114:495-503.
-
(2004)
J Clin Invest.
, vol.114
, pp. 495-503
-
-
Russell, R.R.1
Li, J.2
Coven, D.L.3
Pypaert, M.4
Zechner, C.5
Palmeri, M.6
Giordano, F.J.7
Mu, J.8
Birnbaum, M.J.9
Young, L.H.10
-
23
-
-
0034626730
-
Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1
-
Kleemann R, Hausser A, Geiger G, Mischke R, Burger-Kentischer A, Flieger O, Johannes FJ, Roger T, Calandra T, Kapurniotu A, Grell M, Finkelmeier D, Brunner H, Bernhagen J. Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1. Nature. 2000;408:211-216.
-
(2000)
Nature.
, vol.408
, pp. 211-216
-
-
Kleemann, R.1
Hausser, A.2
Geiger, G.3
Mischke, R.4
Burger-Kentischer, A.5
Flieger, O.6
Johannes, F.J.7
Roger, T.8
Calandra, T.9
Kapurniotu, A.10
Grell, M.11
Finkelmeier, D.12
Brunner, H.13
Bernhagen, J.14
-
24
-
-
0035947235
-
A role for AMP-activated protein kinase in contraction-and hypoxia-regulated glucose transport in skeletal muscle
-
Mu J, Brozinick JT Jr, Valladares O, Bucan M, Birnbaum MJ. A role for AMP-activated protein kinase in contraction-and hypoxia-regulated glucose transport in skeletal muscle. Mol Cell. 2001;7:1085-1094.
-
(2001)
Mol Cell.
, vol.7
, pp. 1085-1094
-
-
Mu, J.1
Brozinick Jr., J.T.2
Valladares, O.3
Bucan, M.4
Birnbaum, M.J.5
-
25
-
-
0029860105
-
NMR characterization of structure, backbone dynamics, and glutathione binding of the human macrophage migration inhibitory factor (MIF)
-
Mühlhahn P, Bernhagen J, Czisch M, Georgescu J, Renner C, Ross A, Bucala R, Holak TA. NMR characterization of structure, backbone dynamics, and glutathione binding of the human macrophage migration inhibitory factor (MIF). Protein Sci. 1996;5:2095-2103.
-
(1996)
Protein Sci.
, vol.5
, pp. 2095-2103
-
-
Mühlhahn, P.1
Bernhagen, J.2
Czisch, M.3
Georgescu, J.4
Renner, C.5
Ross, A.6
Bucala, R.7
Holak, T.A.8
-
26
-
-
77954926921
-
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast
-
Cho Y, Crichlow GV, Vermeire JJ, Leng L, Du X, Hodsdon ME, Bucala R, Cappello M, Gross M, Gaeta F, Johnson K, Lolis EJ. Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proc Natl Acad Sci U S A. 2010;107:11313-11318.
-
(2010)
Proc Natl Acad Sci U S A.
, vol.107
, pp. 11313-11318
-
-
Cho, Y.1
Crichlow, G.V.2
Vermeire, J.J.3
Leng, L.4
Du, X.5
Hodsdon, M.E.6
Bucala, R.7
Cappello, M.8
Gross, M.9
Gaeta, F.10
Johnson, K.11
Lolis, E.J.12
-
27
-
-
84872673868
-
AMPK signalling and the control of substrate use in the heart
-
Nagendran J, Waller TJ, Dyck JR. AMPK signalling and the control of substrate use in the heart. Mol Cell Endocrinol. 2013;366:180-193.
-
(2013)
Mol Cell Endocrinol.
, vol.366
, pp. 180-193
-
-
Nagendran, J.1
Waller, T.J.2
Dyck, J.R.3
-
28
-
-
84858782079
-
AMPK: A nutrient and energy sensor that maintains energy homeostasis
-
Hardie DG, Ross FA, Hawley SA. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol. 2012;13:251-262.
-
(2012)
Nat Rev Mol Cell Biol.
, vol.13
, pp. 251-262
-
-
Hardie, D.G.1
Ross, F.A.2
Hawley, S.A.3
-
29
-
-
79956298543
-
A small molecule AMPK activator protects the heart against ischemia-reperfusion injury
-
Kim AS, Miller EJ, Wright TM, Li J, Qi D, Atsina K, Zaha V, Sakamoto K, Young LH. A small molecule AMPK activator protects the heart against ischemia-reperfusion injury. J Mol Cell Cardiol. 2011;51:24-32.
-
(2011)
J Mol Cell Cardiol.
, vol.51
, pp. 24-32
-
-
Kim, A.S.1
Miller, E.J.2
Wright, T.M.3
Li, J.4
Qi, D.5
Atsina, K.6
Zaha, V.7
Sakamoto, K.8
Young, L.H.9
|