Viral therapy of glioblastoma multiforme

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 29, 2013, Pages 11672-11673

  Whitley, Richard J ^a   Markert, James M ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; INTERLEUKIN 12; NESTIN; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; VASCULOTROPIN;

ANTIANGIOGENIC THERAPY; ASTROCYTE; BRAIN TISSUE; CANCER PATIENT; CANCER SURVIVAL; CELL MIGRATION; CELL RENEWAL; ENCEPHALITIS; GENETIC ENGINEERING; GLIOBLASTOMA; GUINEA PIG; HERPES SIMPLEX VIRUS; HUMAN; NEOVASCULARIZATION (PATHOLOGY); NERVE CELL; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; STEM CELL; TUMOR MICROENVIRONMENT; VIROTHERAPY; VIRUS VIRULENCE;

ANIMALS; DISEASE MODELS, ANIMAL; GLIOBLASTOMA; IMMUNOTHERAPY; INTERLEUKIN-12; ONCOLYTIC VIROTHERAPY; SIMPLEXVIRUS;

EID: 84880369744     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1310253110     Document Type: Note

References (13)

1. Stupp R, et al.; European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups; National Cancer Institute of Canada Clinical Trials Group (2009) Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10(5): 459-466.
2. Cheema TA, et al. (2013) Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model. Proc Natl Acad Sci USA 110-12006-12011.
3. Singh SK, et al. (2003) Identification of a cancer stem cell in human brain tumors. Cancer Res 63(18):5821-5828.
4. Hemmati HD, et al. (2003) Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci USA 100(25): 15178-15183.
5. Liu TC, et al. (2006) Dominant-negative fibroblast growth factor receptor expression enhances antitumoral potency of oncolytic herpes simplex virus in neural tumors. Clin Cancer Res 12(22):6791-6799.
6. Bao S, et al. (2006) Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444(7120):756-760.
7. Le Bé JV, Silberberg G, Wang Y, Markram H (2007) Morphological, electrophysiological, and synaptic properties of corticocallosal pyramidal cells in the neonatal rat neocortex. Cereb Cortex 17(9):2204-2213.
8. Chou J, Kern ER, Whitley RJ, Roizman B (1990) Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture. Science 250(4985)-1262-1266.
9. Whitley RJ, Kern ER, Chatterjee S, Chou J, Roizman B (1993) Replication, establishment of latency, and induced reactivation of herpes simplex virus γ1 34.5 deletion mutants in rodent models. J Clin Invest 91(6):2837-2843.
10. Hellums EK, et al. (2005) Increased efficacy of an interleukin- 12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model. Neuro-oncol 7(3):213-224.
11. Parker JN, et al. (2000) Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors. Proc Natl Acad Sci USA 97(5):2208-2213.
12. Friedman GK, et al. (2013) Pediatric glioma stem cells: Biologic strategies for oncolytic HSV virotherapy. Frontiers Oncol, 10.3389/fonc.2013. 00028.
13. Cheema TA, et al. (2011) Enhanced antitumor efficacy of low-dose etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts. Clin Cancer Res 17(23):7383-7393.