Acute toxicity of proton beam radiation for pediatric central nervous system malignancies

Pediatric Blood and Cancer

Volumn 60, Issue 9, 2013, Pages 1431-1436

  Suneja, Gita ^a   Poorvu, Philip D ^a   Hill Kayser, Christine ^a   Lustig, Robert A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Brain neoplasms radiotherapy; Brain radiation effects; Child protons therapeutic use; Cranial irradiation; Organs at risk radiation effects

Indexed keywords

ACUTE TOXICITY; ADOLESCENT; ADULT; ALOPECIA; ANOREXIA; ARTICLE; CANCER CHEMOTHERAPY; CHILD; CRANIOPHARYNGIOMA; DERMATITIS; EPENDYMOMA; FATIGUE; FEMALE; GERM CELL TUMOR; GLIOMA; HEADACHE; HISTOPATHOLOGY; HUMAN; INFANT; INSOMNIA; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MEDULLOBLASTOMA; NAUSEA; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTON THERAPY; RADIATION DOSE; RHABDOID TUMOR; SCHOOL CHILD; SCORING SYSTEM; TREATMENT DURATION; TUMOR LOCALIZATION; VOMITING;

BRAIN NEOPLASMS/RADIOTHERAPY; BRAIN/RADIATION EFFECTS; CHILD PROTONS/THERAPEUTIC USE; CRANIAL IRRADIATION; ORGANS AT RISK/RADIATION EFFECTS;

ADOLESCENT; ADULT; AGE FACTORS; ALOPECIA; ANOREXIA; CENTRAL NERVOUS SYSTEM NEOPLASMS; CHILD; CHILD, PRESCHOOL; CRANIOSPINAL IRRADIATION; FEMALE; HEADACHE; HUMANS; INFANT; MALE; NAUSEA; PROTON THERAPY; RADIATION INJURIES; RETROSPECTIVE STUDIES; SLEEP INITIATION AND MAINTENANCE DISORDERS; TIME FACTORS; VOMITING;

EID: 84880365750     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.24554     Document Type: Article

References (24)

1. Ries LAG, Smith MA, Gurney JG, et al. Cancer Incidence and Survival among Children and Adolescents: United States SEER Program 1975-1995, 1999 NIH Pub. No. 99-4649.
2. Gunderson L, Tepper J. Clinical radiation oncology, 3rd edition. Philadelphia: Saunders; 2011; 1409-1423.
3. Armstrong GT. Long-term survivors of childhood central nervous system malignancies: The experience of the Childhood Cancer Survivor Study. Eur J Pediatr Neurol 2010; 14:298-303.
4. Mulhern RK, Palmer SL, Merchant TE, et al. Neurocognitive consequences of risk-adapted therapy for childhood medulloblastoma. J Clinical Oncol 2005; 23:5511-5519.
5. Geenen MM, Cardous-Ubbink MC, Kremer LCM, et al. Medical assessment of adverse health outcomes in long-term survivors of childhood cancer. JAMA 2007; 297:2705-2715.
6. Bhat SR, Goodwin TL, Burwinkle TM, et al. Profile of daily life in children with brain tumors: An assessment of health-related quality of life. J Clin Oncol 2005; 23:5493-5500.
7. Pui C-H, Cheng C, Leung W, et al. Extended follow-up of long-term survivors of childhood acute lymphoblastic leukemia. N Engl J Med 2003; 349:640-649.
8. Merchant TE, Hua C-H, Shukla H, et al. Proton versus photon radiotherapy for common pediatric brain tumors: Comparison of models of dose characteristics and their relationship to cognitive function. Pediatr Blood Cancer 2008; 51:110-117.
9. Glimelius B, Isacsson U, Blomquist E, et al. Potential gains using high-energy protons for therapy of malignant tumours. Acta oncologica 1999; 38:137-145.
10. Kuhlthau KA, Pulsifer MB, Yeap BY, et al. Prospective study of health-related quality of life for children with brain tumors treated with proton radiotherapy. J Clin Oncol 2012; 30:2079-2086.
11. Jereczek-Fossa BA, Jassem J, Orecchia R. Cervical lymph node metastases of squamous cell carcinoma from an unknown primary. Cancer Treat Rev 2004; 30:153-164.
12. Merchant TE. Three-dimensional conformal radiation therapy for ependymoma. Childs Nerv Syst 2009; 25:1261-1268.
13. Hall EJ, Giaccia AJ. Radiobiology for the radiobiologist, 7th edition. Philadelphia: Lippincott Williams & Wilkins; 2011.
14. Donahue B. Short- and long-term complications of radiation therapy for pediatric brain tumors. Pediatr Neurosurg 1992; 18:207-217.
15. Chang EL, Allen P, Wu C, et al. Acute toxicity and treatment interruption related to electron and photon craniospinal irradiation in pediatric patients treated at the University of Texas M.D. Anderson Cancer Center. Int J Radiat Oncol Biol Phys 2002; 52:1008-1016.
16. Kun LE, Beltran C. Radiation therapy for children: Evolving technologies in the era of ALARA. Pediatr Radiol 2009; 39:S65-S70.
17. MacDonald SM, Safai S, Trofimov A, et al. Proton radiotherapy for childhood ependymoma: Initial clinical outcomes and dose comparisons. Int J Radiat Oncol Biol Phys 2008; 71:979-986.
18. Luu QT, Loredo LN, Archambeau JO, et al. Fractionated proton radiation treatment for pediatric craniopharyngioma: Preliminary report. Cancer J 12:155-159.
19. Lee CT, Bilton SD, Famiglietti RM, et al. Treatment planning with protons for pediatric retinoblastoma, medulloblastoma, and pelvic sarcoma: How do protons compare with other conformal techniques? Int J Radiat Oncol Biol Phys 2005; 63:362-372.
20. Yock T, Schneider R, Friedmann A, et al. Proton radiotherapy for orbital rhabdomyosarcoma: Clinical outcome and a dosimetric comparison with photons. Int J Radiat Oncol Biol Phys 2005; 63:1161-1168.
21. St Clair WH, Adams JA, Bues M, et al. Advantage of protons compared to conventional X-ray or IMRT in the treatment of a pediatric patient with medulloblastoma. Int J Radiat Oncol Biol Phys 2004; 58:727-734.
22. Lin R, Hug EB, Schaefer RA, et al. Conformal proton radiation therapy of the posterior fossa: A study comparing protons with three-dimensional planned photons in limiting dose to auditory structures. Int J Radiat Oncol Biol Phys 2000; 48:1219-1226.
23. Yuh GE, Loredo LN, Yonemoto LT, et al. Reducing toxicity from craniospinal irradiation: Using proton beams to treat medulloblastoma in young children. Cancer J 10:386-390.
24. Fuss M, Hug EB, Schaefer RA, et al. Proton radiation therapy (PRT) for pediatric optic pathway gliomas: Comparison with 3D planned conventional photons and a standard photon technique. Int J Radiat Oncol Biol Phys 1999; 45:1117-1126.