Soluble ICAM-1 levels in small-cell lung cancer: Prognostic value for survival and predictive significance for response during chemotherapy

Medical Oncology

Volumn 30, Issue 3, 2013, Pages

  Kotteas, Elias A ^a   Gkiozos, Ioannis ^a   Tsagkouli, Sofia ^a   Bastas, Antonios ^a   Ntanos, Ioannis ^a   Saif, Muhammad W ^b   Syrigos, Konstantinos N ^a,c  

^a SOTIRIA GENERAL HOSPITAL   (Greece)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chemotherapy; Response; Small cell lung cancer; Soluble ICAM 1

Indexed keywords

CARBOPLATIN; ETOPOSIDE; INTERCELLULAR ADHESION MOLECULE 1; CELL ADHESION MOLECULE; TUMOR MARKER;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; CANCER CHEMOTHERAPY; CANCER STAGING; CANCER SURVIVAL; CLINICAL ARTICLE; CORRELATION ANALYSIS; DEATH; DIAGNOSTIC TEST ACCURACY STUDY; DRUG RESPONSE; FEMALE; FUNCTIONAL STATUS; HUMAN; LUNG SMALL CELL CANCER; MALE; MIDDLE AGED; MULTIPLE CYCLE TREATMENT; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE; PRIORITY JOURNAL; PROGNOSIS; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SMOKING; STATISTICAL SIGNIFICANCE; BLOOD; LUNG TUMOR; MORTALITY; PATHOLOGY; SMALL CELL LUNG CANCER;

AGED; CELL ADHESION MOLECULES; FEMALE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LUNG NEOPLASMS; MALE; MIDDLE AGED; PROGNOSIS; SMALL CELL LUNG CARCINOMA; TUMOR MARKERS, BIOLOGICAL;

EID: 84880334469     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-013-0662-0     Document Type: Article

References (13)

1. Siegel R, Naishadham D, Jemal A. Cancer statistics 2012. CA Cancer J Clin. 2012;62:10-29.
2. Aznavoorian S, Murphy AN, Stetler-Stevenson WG, Liotta LA. Molecular aspects of tumor cell invasion and metastasis. Cancer. 1993;71:1368-83.
3. Gho YS, Kleinman HK, Sosne G. Angiogenic activity of human soluble intercellular adhesion molecule-1. Cancer Res. 1999;59: 5128-32.
4. Gho YS, Kim PN, Li HC, Elkin M, Kleinman HK. Stimulation of tumor growth by human soluble intercellular adhesion molecule-1. Cancer Res. 2001;61:4253-7.
5. Gearing AJ, Newman W. Circulating adhesion molecules in disease. Immunol Today. 1993;10:506-12.
6. Kostler WJ, Tomek S, Brodowicz T, Budinsky AC, Flamm M, Hejna M, Krainer M, Wiltschke C, Zielinski CC. Soluble ICAM- 1 in breast cancer: clinical significance and biological implications. Cancer Immunol Immunother. 2001;50:483-90.
7. Kageshita T, Yoshii A, Kimura T, Kuriya N, Ono T, Tsujisaki M, Imai K, Ferrone S. Clinical relevance of ICAM-1 expression in primary lesions and serum of patients with malignant melanoma. Cancer. 1993;53:4927-32.
8. Alexiou D, Karayiannakis AJ, Syrigos KN, Zbar A, Kremmyda A, Bramis I, Tsigris C. Serum levels of E-selectin, ICAM-1 and VCAM-1 in colorectal cancer patients: correlation with clinicopathological features, patient survival and tumour surgery. Eur J Cancer. 2001;37:2392-7.
9. Alexiou D, Karayiannakis AJ, Syrigos KN, Zbar A, Sekara E, Michail P, Rosenberg T, Diamantis T. Clinical significance of serum levels of E-selectin, intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in gastric cancer patients. Am J Gastroenterol. 2003;98:478-85.
10. Qian Q, Zhan P, Yu L, Shi Y, Cheng J, Wei S, Wang Q, Song Y. Baseline levels and decrease in serum soluble intercellular adhesion molecule-1 during chemotherapy predict objective response and survival in patients who have advanced non-smallcell lung cancer. Clin Lung Cancer. 2011;12:131-7.
11. Grothey A, Heistermann P, Philippou S, Voigtmann R. Serum levels of soluble adhesion molecule-1 (ICAM-1, CD54) in patients with non-small cell lung cancer: correlation with histological expression of ICAM-1 and tumor stage. Br J Cancer. 1998;77:801-7.
12. Finzel AH, Reininger AJ, Bode PA, Wurzinger LJ. ICAM-1 supports adhesion of human small-cell lung carcinoma to endothelial cells. Clin Exp Metastasis. 2004;21:185-9.
13. Cogali A, Charalabopoulos K, Zampira I, Konstantinidis A, Tachmazoglou F, Daskalopoulos G, Constantopoulos S, Dalavanga Y. Soluble adhesion molecules E-cadherin, Intercellular adhesion molecule-1 and E-selectin as lung cancer biomarkers. Chest. 2010;138:1173-9.