Chronic progressive external ophthalmoplegia coexistent with motor neuron disease in a patient with a novel large-scale mitochondrial DNA deletion

Clinical Neurology and Neurosurgery

Volumn 115, Issue 8, 2013, Pages 1490-1492

  Zhao, Danhua ^a   Wang, Zhaoxia ^a   Hong, Daojun ^a   Zhang, Wei ^a   Yuan, Yun ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

Author keywords

Chronic progressive external ophthalmoplegia; Large scale deletion; Mitochondrial DNA; Motor neuron disease

Indexed keywords

CREATINE KINASE; LACTIC ACID; MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE;

AGED; ARTICLE; BICEPS BRACHII MUSCLE; BRAIN ATROPHY; CASE REPORT; CHINESE; CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA; CYTOCHROME C OXIDASE DEFICIENCY; DISEASE COURSE; DYSARTHRIA; ELECTROMYOGRAPHY; ELECTRON MICROSCOPY; ENZYME SUBUNIT; FASCICULATION; GENE DELETION; HUMAN; HUMAN TISSUE; LACTATE BLOOD LEVEL; LIMB WEAKNESS; MALE; MEDICAL HISTORY; MOTOR NEURON DISEASE; MOTOR UNIT POTENTIAL; MUSCLE ATROPHY; MUSCLE BIOPSY; MUSCLE WEAKNESS; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYMERASE CHAIN REACTION; PTOSIS; QUADRICEPS FEMORIS MUSCLE; SOUTHERN BLOTTING; TENDON REFLEX; TIBIALIS ANTERIOR MUSCLE;

CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA; LARGE-SCALE DELETION; MITOCHONDRIAL DNA; MOTOR NEURON DISEASE;

AGED; ATROPHY; BLOTTING, SOUTHERN; DNA, MITOCHONDRIAL; FASCICULATION; GENE DELETION; HUMANS; MALE; MOTOR NEURON DISEASE; MUSCLE FIBERS, SKELETAL; MUSCLE WEAKNESS; MUSCLE, SKELETAL; OPHTHALMOPLEGIA, CHRONIC PROGRESSIVE EXTERNAL; POLYMERASE CHAIN REACTION;

EID: 84880325519     PISSN: 03038467     EISSN: 18726968     Source Type: Journal    
DOI: 10.1016/j.clineuro.2012.11.011     Document Type: Article

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