Measurement of free carnitine and acylcarnitines in plasma by HILIC-ESI-MS/MS without derivatization

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 932, Issue , 2013, Pages 12-18

  Peng, Minzhi ^a   Liu, Li ^a   Jiang, Minyan ^a   Liang, Cuili ^a   Zhao, Xiaoyuan ^a   Cai, Yanna ^a   Sheng, Huiying ^a   Ou, Zhiying ^a   Luo, Hong ^b  

^a GUANGZHOU WOMEN AND CHILDREN S MEDICAL CENTER   (China)

^b Guangzhou Blood Center   (China)

Author keywords

Acylcarnitine isomer; Fatty acid oxidation disorders; HILIC; LC MS MS; Organic acidemia

Indexed keywords

ACYLCARNITINE; FATTY ACID OXIDATION; HILIC; HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHIES; LC-MS/MS; ORGANIC ACIDEMIA; TANDEM MASS SPECTROMETRY; VALIDATED METHODS;

FATTY ACIDS; ISOMERS; MASS SPECTROMETRY;

OXIDATION;

ACYLCARNITINE; CARNITINE; DICARBOXYLIC ACID; HYDROXYL GROUP;

ACIDEMIA; AMINO ACID BLOOD LEVEL; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DERIVATIZATION; ELECTROSPRAY MASS SPECTROMETRY; FALSE POSITIVE RESULT; FATTY ACID OXIDATION; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; MEASUREMENT ACCURACY; METABOLIC DISORDER; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

18-OH; AAPS; ACETYLCARNITINE; ACYLCARNITINE ISOMER; AMERICAN ASSOCIATION OF PHARMACEUTICAL SCIENTISTS; BOVINE SERUM ALBUMIN; BSA; BUTYRYLCARNITINE; C0; C10; C12; C14; C16; C16-OH; C16:1-OH; C18; C18:1-OH; C2; C3; C4; C4DC; C5; C5:1; C5DC; C6; C6-OH; C8; C8-OH; CARNITINE; CE; CITRATE PHOSPHATE DEXTROSE ADENINE; COLLISION ENERGY; CPDA; DECANOYLCARNITINE; DECLUSTERING POTENTIAL; DP; ELECTROSPRAY ION SOURCE; ENHANCED PRODUCT ION MONITORING; EPI; ESI; FATTY ACID Β-OXIDATION DISORDERS; FIA-MS/MS; FLOW INJECTION TANDEM MASS SPECTROMETRY; GLUTARYLCARNITINE; HEXANOYLCARNITINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HILIC; HPLC; HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY; HYDROXY HEXANOYLCARNITINE; HYDROXY OCTANOYLCARNITINE; HYDROXY-HEXADECANOYLCARNITINE; HYDROXY-OCTADECANOYLCARNITINE; HYDROXY-OCTADECENOYLCARNITINE; HYDROXY-PALMITOLEOYLCARNITINE; IDA; INFORMATION DEPENDENT ACQUISITION; INTERNAL STANDARD; IS; ISOVALERYLCARNITINE; LAUROYLCARNITINE; LC-MS/MS; MRM; MULTIPLE REACTION MONITORING; MYRISTOYLCARNITINE; OCTANOYLCARNITINE; ORGANIC ACIDEMIA; PALMITOYLCARNITINE; PBS; PHOSPHATE BUFFER SOLUTION; PROPIONYLCARNITINE; QCS; QUALITY CONTROL SAMPLES; STEAROYLCARNITINE; SUCCINYLCARNITINE AND METHYLMALONYLCARNITINE; TIGLYLCARNITINE;

CARNITINE; CHROMATOGRAPHY, LIQUID; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; ISOMERISM; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84880294771     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2013.05.028     Document Type: Article

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