Synthetic and natural protease inhibitors provide insights into parasite development, virulence and pathogenesis

Current Medicinal Chemistry

Volumn 20, Issue 25, 2013, Pages 3078-3102

  Rascon Jr A A ^a   McKerrow, J H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Development; Digestion; Helminths; Hemoglobin; Kinetoplastids; Nutrition acquisition; Parasites; Pathogenesis; Protease inhibitors; Proteases; Protozoa; Virulence factors

Indexed keywords

ASPARTIC PROTEINASE; CATHEPSIN B; CATHEPSIN L; CYSTEINE; CYSTEINE PROTEINASE; HEMOGLOBIN; HUMAN IMMUNOGLOBULIN; K 11777; METALLOPROTEINASE; N (3 PROPYLCARBAMOYLOXIRANE 2 CARBONYL)ISOLEUCYLPROLINE; OLIGOPEPTIDASE B; PAPAIN; PROTEINASE INHIBITOR; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; WRR 483; WRR 605;

ANCYLOSTOMA CANINUM; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; BRUGIA PAHANGI; CAENORHABDITIS ELEGANS; CD4+ T LYMPHOCYTE; CELL DEATH; CELL INVASION; CERCARIA; CLONORCHIS SINENSIS; CYTOLYSIS; DISEASE COURSE; DRUG INHIBITION; ECHINOCOCCOSIS; ENCEPHALITIS; ENTAMOEBA; ENTAMOEBA HISTOLYTICA; ENZYME ACTIVITY; ERYTHROCYTE; FASCIOLA HEPATICA; GENE DISRUPTION; GIARDIA; HELMINTH; HUMAN; IMMUNOLOCALIZATION; KINETOPLASTIDA; MALARIA; MOLTING; NEMATODE; NONHUMAN; NUTRITION; ONCHOCERCA VOLVULUS; PARAGONIMUS WESTERMANI; PARASITE DEVELOPMENT; PATHOGENESIS; PLASMODIUM FALCIPARUM; PROTEIN ANALYSIS; RNA INTERFERENCE; SCHISTOSOMA MANSONI; TAENIA SAGINATA; TROPHOZOITE; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI; VIRULENCE;

AMINOPEPTIDASES; ANIMALS; CESTODA; CYSTATINS; CYSTEINE PROTEASES; HELMINTH PROTEINS; HELMINTHS; HUMANS; NEMATODA; PROTEASE INHIBITORS; SERPINS; TREMATODA; VIRULENCE;

EID: 84880292194     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/0929867311320250005     Document Type: Article

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