A validated clinical tool for the prediction of varices in PBC: The Newcastle Varices in PBC Score

Journal of Hepatology

Volumn 59, Issue 2, 2013, Pages 327-335

  Patanwala, Imran ^a,b,c   McMeekin, Peter ^d   Walters, Ruth ^a,b   Mells, George ^e   Alexander, Graeme ^e   Newton, Julia ^a,b   Shah, Hemant ^f   Coltescu, Catalina ^f   Hirschfield, Gideon M ^f,g   Hudson, Mark ^a,b   Jones, Dave ^a,b  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b FREEMAN HOSPITAL   (United Kingdom)

^c ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

^e CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^f TORONTO WESTERN HOSPITAL   (Canada)

^g UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Chronic; Health economics; Liver disease; Portal hypertension

Indexed keywords

ALBUMIN; ALKALINE PHOSPHATASE;

ADULT; ARTICLE; ESOPHAGOGASTRODUODENOSCOPY; ESOPHAGUS VARICES; ESOPHAGUS VARICES BLEEDING; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; NEWCASTLE VARICES IN PBC SCORE; PREVALENCE; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; SURVIVAL; THROMBOCYTE; TRANSPLANT FREE SURVIVAL; VALIDATION PROCESS;

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ALP; ALT; AREA UNDER THE RECEIVER OPERATING CHARACTERISTIC CURVE; AUROC; BIL; BILIRUBIN; CHRONIC; CI; CONFIDENCE INTERVAL; GASTRO-OESOPHAGEAL VARICES; GOV; HEALTH ECONOMICS; INTERQUARTILE RANGE; IQR; LIVER DISEASE; MABPT; MALES ALBUMIN<3.5 G/DL BILIRUBIN >1.2 MG/DL &/OR PT > 12.9S; NEWCASTLE VARICES IN PBC SCORE; NVP SCORE; OESOPHAGEO-GASTRO-DUODENOSCOPY; OGD; PBC; PORTAL HYPERTENSION; PRIMARY BILIARY CIRRHOSIS; PROTHROMBIN TIME; PT; RECEIVER OPERATING CHARACTERISTIC CURVE; ROC; UDCA; URSODEOXYCHOLIC ACID;

AGED; ALKALINE PHOSPHATASE; COHORT STUDIES; CROSS-SECTIONAL STUDIES; ENDOSCOPY, GASTROINTESTINAL; ESOPHAGEAL AND GASTRIC VARICES; FEMALE; GREAT BRITAIN; HUMANS; LIVER CIRRHOSIS, BILIARY; MALE; MIDDLE AGED; ONTARIO; PLATELET COUNT; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; RISK FACTORS; SERUM ALBUMIN;

EID: 84880287870     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.04.010     Document Type: Article

References (24)

1. Y. Nakanuma Are esophagogastric varices a late manifestation in primary biliary cirrhosis? J Gastroenterol 38 2003 1110 1112
2. E. Takeshita, T. Kumagi, H. Matsui, M. Abe, S. Furukawa, and Y. Ikeda Esophagogastric varices as a prognostic factor for the determination of clinical stage in patients with primary biliary cirrhosis J Gastroenterol 38 2003 1060 1065
3. A. Rydning, E. Schrumpf, M. Abdelnoor, K. Elgjo, and E. Jenssen Factors of prognostic importance in primary biliary cirrhosis Scand J Gastroenterol 25 1990 119 126
4. G.J. Gores, R.H. Wiesner, E.R. Dickson, A.R. Zinsmeister, R.A. Jorgensen, and A. Langworthy Prospective evaluation of esophageal varices in primary biliary cirrhosis: development, natural history, and influence on survival Gastroenterology 96 1989 1552 1559
5. S. Sherlock Primary biliary cirrhosis (chronic intrahepatic obstructive jaundice) Gastroenterology 37 1959 574 586
6. F. Colina, F. Pinedo, J.A. Solís, D. Moreno, and M. Nevado Nodular regenerative hyperplasia of the liver in early histological stages of primary biliary cirrhosis Gastroenterology 102 1992 1319 1324
7. M.C. Kew, R.R. Varma, H.A.D. Santos, and P.J. Scheuer Portal hypertension in primary biliary cirrhosis Gut 12 1971 830 834
8. J.R. Thornton, D.R. Triger, and M.S. Losowsky Variceal bleeding is associated with reduced risk of severe cholestasis in primary biliary cirrhosis QJM 71 1989 467 471
9. A.H.M. Ali, E.M.D. Sinakos, M.G.M.D. Silveira, R.A.M.S.R.N. Jorgensen, P.M.D. Angulo, and K.D.M.D. Lindor Varices in early histological stage primary biliary cirrhosis J Clin Gastroenterol 45 2011 e66 e71
10. European Association for the Study of the L EASL Clinical Practice Guidelines: management of cholestatic liver diseases J Hepatol 51 2009 237 267
11. K.D. Lindor, M.E. Gershwin, R. Poupon, M. Kaplan, N.V. Bergasa, and E.J. Heathcote Primary biliary cirrhosis Hepatology 50 2009 291 308
12. M.C. Garrido, and S.G. Hubscher Accuracy of staging in primary biliary cirrhosis J Clin Path 49 1996 556 559
13. C. Levy, C.O. Zein, J. Gomez, C. Soldevila-Pico, R. Firpi, and G. Morelli Prevalence and predictors of esophageal varices in patients with primary biliary cirrhosis Clin Gastroenterol Hepatol 5 2007 803 808
14. B. Bressler, R. Pinto, D. El-Ashry, and E.J. Heathcote Which patients with primary biliary cirrhosis or primary sclerosing cholangitis should undergo endoscopic screening for oesophageal varices detection? Gut 54 2005 407 410
15. P. Angulo, K.D. Lindor, T.M. Therneau, R.A. Jorgensen, M. Malinchoc, and P.S. Kamath Utilization of the Mayo risk score in patients with primary biliary cirrhosis receiving ursodeoxycholic acid Liver 19 1999 115 121
16. O.F.W. James, R. Bhopal, D. Howel, J. Gray, A.D. Burt, and J.V. Metcalf Primary biliary cirrhosis once rare, now common in the UK? Hepatology 30 1999 390 394
17. J.V. Metcalf, R.S. Bhopal, J. Gray, and O.F.W. James Incidence and prevalence of primary biliary cirrhosis in the city of Newcastle-upon-Tyne Engl Int J Epidemiol 26 1997 830 836
18. M.I. Prince, A. Chetwynd, P. Diggle, M. Jarner, J.V. Metcalf, and O.F.W. James The geographical distribution of primary biliary cirrhosis in a well-defined cohort Hepatology 34 2001 1083 1088
19. P.J. Scheuer Primary biliary cirrhosis Proc R Soc Med 60 1967
20. M.R. Biagini, M. Guardascione, A.P. McCormick, C. Raskino, N. McIntyre, and A.K. Burroughs Bleedings varices in PBC and its prognostic significance Gut 31 1990 A1209
21. P.-M. Huet, C. Vincent, J. Deslaurier, J. Cote, S. Matsutami, and R. Boileau Portal hypertension and primary biliary cirrhosis: effect of long-term ursodeoxycholic acid treatment Gastroenterology 135 2008 1552 1560
22. P. Angulo, K.D. Lindor, and T.M. Therneau Utilization of the Mayo risk score in patients with primary biliary cirrhosis receiving ursodeoxycholic acid Liver 19 1999 115 121
23. E.M.M. Kuiper, B.E. Hansen, and R.A. de Vries Improved prognosis of patients with primary biliary cirrhosis that have a biochemical response to ursodeoxycholic acid Gastroenterology 136 2009 1281 1287
24. A. Parés, L. Caballería, and J. Rodés Excellent Long-Term Survival in Patients With Primary Biliary Cirrhosis and Biochemical Response to Ursodeoxycholic Acid Gastroenterology 130 2006 715 720