Comparison of acellular and cellular bioactivity of poly 3-hydroxybutyrate/hydroxyapatite nanocomposite and poly 3-hydroxybutyrate scaffolds

Biotechnology and Bioprocess Engineering

Volumn 18, Issue 3, 2013, Pages 587-593

  Saadat, Abbas ^a   Behnamghader, Aliasghar ^b   Karbasi, Saeed ^c   Abedi, Daryoush ^d   Soleimani, Masoud ^e   Shafiee, Abbas ^f,g  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b MATERIALS AND ENERGY RESEARCH CENTER   (Iran)

^c ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e TARBIAT MODARES UNIVERSITY   (Iran)

^f TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^g STEM CELL TECHNOLOGY RESEARCH CENTER   (Iran)

Author keywords

acellular bioactivity; bone tissue engineering; cell response; poly 3 hydroxybutyrate hydroxyapatite nanocomposite scaffolds

Indexed keywords

ALKALINE PHOSPHATASE ACTIVITY; BONE TISSUE ENGINEERING; CELL RESPONSE; HYDROXYAPATITE NANOPARTICLES; NANOCOMPOSITE SCAFFOLDS; POLY-3-HYDROXYBUTYRATE; SIMULATED BODY FLUIDS; TISSUE ENGINEERING APPLICATIONS;

BIOACTIVITY; CELL CULTURE; EXPERIMENTS; NANOCOMPOSITES; NANOPARTICLES; PHOSPHATASES; TRANSMISSION ELECTRON MICROSCOPY;

SCAFFOLDS (BIOLOGY);

ALKALINE PHOSPHATASE; HYDROXYAPATITE; MOLECULAR SCAFFOLD; NANOCOMPOSITE; POLY(3 HYDROXYBUTYRIC ACID); POLY(3 HYDROXYBUTYRIC ACID) HYDROXYAPATITE COPOLYMER; SOLVENT; UNCLASSIFIED DRUG;

ARTICLE; BODY FLUID; CAST APPLICATION; CELL ADHESION; CELL PROLIFERATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENERGY DISPERSIVE X RAY ANALYSIS; ENZYME ACTIVITY; IMMERSION; LEACHING; NANOFABRICATION; PARTICLE SIZE; POROSITY; SCANNING ELECTRON MICROSCOPY; SIMULATED BODY FLUID; TRANSMISSION ELECTRON MICROSCOPY; X RAY ANALYSIS; X RAY DIFFRACTION;

EID: 84880283670     PISSN: 12268372     EISSN: 19763816     Source Type: Journal    
DOI: 10.1007/s12257-012-0744-4     Document Type: Article

References (26)

1. Hutmacher, D. W., T. Schantz, I. Zien, K. W. Ng, S. H. Teoh, and K. C. Tan (2001) Mechanical properties an md cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling. J. Biomed. Mater. Res. 55: 203-216.
2. Nejati, E., H. Mirzadeh, and M. Zandi (2008) Synthesis and characterization of nano-hydroxyapatite rods/poly (L-lactide acid) composite scaffolds for bone tissue engineering. Composites: Part A 39: 1589-1596.
3. Chen, Y., A. F. T. Mak, M. Wang, J. Li, and M. S. Wong (2006) PLLA scaffolds with biomimetic apatite coating and biomimetic apatite/collagen composite coating to enhance osteoblast-like cells attachment and activity. Surf. Coat. Technol. 201: 575-580.
4. Wang, Y. W., Q. Wu, J. Chen, and G. Q. Chen (2005) Evaluation of three-dimensional scaffolds made of blends of hydroxyapatite and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) for bone reconstruction. Biomat. 26: 899-904.
5. Valappil, S. P., S. K. Misra, A. R. Boccaccini, and I. Roy (2006) Biomedical applications of polyhydroxyalkanoates: An overview of animal testing and in vivo responses. Expert Rev. Med. Dev. 3: 853-868.
6. Anderson, A. J. and E. A. Dawes (1990) Occurrence, metabolism, metabolic role and industrial uses of Bacterial polyhydroxyalkanoates. Microbiol. Rev. 54: 450-472.
7. Misra Superb, K., M. Dirk, J. Brunner Tobias, J. Stark Wendelin, E. Philip Sheryl, R. Ipsita, S. Vehid, C. Knowles Jonathan, and R. Boccaccini Aldo (2008) Comparison of nanoscale and microscale bioactive glass on the properties of P(3HB)/Biogas- composites. Biomat. 29: 1750-1761.
8. Knowles, J. C., F. A. Mahmud, and G. W. Hastings (1991) Piezoelectric characteristics of polyhydroxybutyrate based composite. Clinic. Mat. 8: 155-158.
9. Cengiz, B., Y. Gokce, N. Yildiz, and Z. Aktas (2008) Calimli Synthesis and characterization of hydroxyapatite nanoparticles. Colloids and Surfaces A: Physicochem. Eng. Aspects 322: 29-33.
10. Chen, D. Z., C. Y. Tang, K. C. Chan, C. P. Tsui, P. H. F. Yu, M. C. P. Leung, and P. S. Uskokovic (2007) Dynamic mechanical properties and in vitro bioactivity of PHBHV/HA nanocomposite. Comp. Sci. Technol. 67: 1617-1626.
11. Webster, T. J. and R. W. Siegel (1999) Bizios Osteoblast adhesion on nanophase ceramics. Biomat. 20: 1221-1227.
12. Matsuura T., R. Hosokawa, K. Okamoto, T. Kimoto, and Y. Akagawa (2000) Diverse mechanisms of osteoblast spreading on hydroxyapatite and titanium. Biomat. 21: 1121-1127.
13. Chen, L., J. M. Mccrate, J. C. Lee, and H. Li (2011) The role of surface charge on the uptake and biocompatibility of hydroxyapatite nanoparticles with osteoblast cells. Nanotechnol. 22: 105708.
14. Wu, C. L., W. G. Weng, and D. J. Wu (2003) Yan Preparation of polystyrene/graphite nanosheet composite. Polymer 44: 1781-1784.
15. Rajabi-Zamani, A. H., A. Behnamghader, and A. Kazemzadeh (2008) Synthesis of nanocrystalline carbonated hydroxyapatite powder via nonalkoxide sol-gel method. Mat. Sci. Eng: C 28: 1326-1329.
16. Yung-Chih, K. and L. Sho-Noen (2006) effects of composition, solvent, and salt particles on the physicochemical properties of polyglycolide/Poly(lactide- co-glycolide) Scaffolds. Biotechnol. Prog. 22: 1664-1670.
17. Kokubo, T., H. Kushitani, S. Sakka, T. Kitsugi, and T. Yamamuro (1990) Solutions able to reproduce in vivo surface-structure changes in bioactive glassceramic A-W. J. Biomed. Mater. Res. 24: 721-734.
18. Quarto Engineered Bone: Tissue Engineering of Bone. http://Eurekah.com.
19. Zhang N., L. N. Heather, T. Shila, and W. Xuejun (2007) Fabrication of nanocrystalline hydroxyapatite doped degradable composite hollow fiber for guided and biomimetic bone tissue engineering. Mat. Sci. Eng: C 27: 599-606.
20. Boccaccini, A. R., J. A. Roether, L. L. Hench, V. Maquet, and R. Jérôme (2002) A composites approach to tissue engineering. Ceram. Eng. Sci. Proc. 23: 805-816.
21. Boccaccini, A. R. and V. Maquet (2003) Bioresorbable and bioactive polymer/Bioglass - composites with tailored pore structure for tissue engineering applications. Comp. Sci. Technol. 63: 2417-2423.
22. Roether, J. A., A. R. Boccaccini, L. L. Hench, V. Maquet, S. Gautier, and R. Jérôme (2002) Development and in-vitro characterisation of novel bioresorbable and bioactive composite materials based on polylactide foams and Bioglass for tissue engineering applications. Biomat. 23: 3871-3878.
23. Leonor, I. B., A. Ito, K. Onuma, N. Kanzaki, and R. L. Reis (2003) In vitro bioactivity of starch thermoplastic/hydroxyapatite composite biomaterials: An in situ study using atomic force microscopy. Biomat. 24: 579-585.
24. Zheng, J. P., C. Z. Wang, X. X. Wang, H. Y. Wang, H. Zhuang, and K. D. Yao (2007) Preparation of biomimetic three-dimensional gelatin/montmorillonite- chitosan scaffold for tissue engineering. Reactive & Functional Polymers 67: 780-788.
25. Yoshihiro, I., H. Hasuda, M. Kamitakahara, C. Ohtsuki, M. Tanihara, I. K. Kang, and O. H. Kwon (2005) A composite of hydroxyapatite with electrospun biodegradable nanofibers as a tissue engineering material. J. Biosci. Bioeng. 100: 43-49.
26. Woo, K. M., V. J. Chen, and P. X. Ma (2003) Nano-fibrous scaffolding architecture selectively enhances protein absorption contributing to cell attachment. J. Biomed. Mater. Res. 67: 531-537.