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Volumn 63, Issue SUPPL. 2, 2013, Pages

Preparing for the unexpected: The pivotal role of social and behavioral sciences in trials of biomedical HIV prevention interventions

Author keywords

Adherence; Behavioral science; Biomedical interventions; HIV; Populations; Social science

Indexed keywords

MICROBICIDE; TENOFOVIR;

EID: 84880235980     PISSN: 15254135     EISSN: 10779450     Source Type: Journal    
DOI: 10.1097/QAI.0b013e31829a3a4d     Document Type: Article
Times cited : (20)

References (48)
  • 1
    • 80051633217 scopus 로고    scopus 로고
    • Prevention of HIV-1 infection with early antiretroviral therapy
    • Cohen MS, Chen YQ, McCauley M, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365:493-505.
    • (2011) N Engl J Med. , vol.365 , pp. 493-505
    • Cohen, M.S.1    Chen, Y.Q.2    McCauley, M.3
  • 2
    • 28444460441 scopus 로고    scopus 로고
    • Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: The ANRS 1265 Trial
    • Auvert B, Taljaard D, Lagarde E, et al. Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 Trial. PLoS Med. 2005;2:e298.
    • (2005) PLoS Med. , vol.2
    • Auvert, B.1    Taljaard, D.2    Lagarde, E.3
  • 3
    • 33847151707 scopus 로고    scopus 로고
    • Male circumcision for HIV prevention in young men in Kisumu Kenya: A randomised controlled trial
    • Bailey RC, Moses S, Parker CB, et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Lancet. 2007;369:643-656.
    • (2007) Lancet. , vol.369 , pp. 643-656
    • Bailey, R.C.1    Moses, S.2    Parker, C.B.3
  • 4
    • 33847104829 scopus 로고    scopus 로고
    • Male circumcision for HIV prevention in men in Rakai Uganda: A randomised trial
    • Gray RH, Kigozi G, Serwadda D, et al. Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial. Lancet. 2007; 369:657-666.
    • (2007) Lancet. , vol.369 , pp. 657-666
    • Gray, R.H.1    Kigozi, G.2    Serwadda, D.3
  • 5
    • 84864505868 scopus 로고    scopus 로고
    • Antiretroviral prophylaxis for HIV prevention in heterosexual men and women
    • Baeten JM, Donnell D, Ndase P, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med. 2012;367: 399-410.
    • (2012) N Engl J Med. , vol.367 , pp. 399-410
    • Baeten, J.M.1    Donnell, D.2    Ndase, P.3
  • 6
    • 78650549662 scopus 로고    scopus 로고
    • Preexposure chemoprophylaxis for HIV prevention in men who have sex with men
    • Grant RM, Lama JR, Anderson PL, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010; 363:2587-2599.
    • (2010) N Engl J Med. , vol.363 , pp. 2587-2599
    • Grant, R.M.1    Lama, J.R.2    Anderson, P.L.3
  • 7
    • 77955930318 scopus 로고    scopus 로고
    • Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
    • Abdool Karim Q, Abdool Karim SS, Frohlich JA, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science. 2010;329:1168-1174.
    • (2010) Science. , vol.329 , pp. 1168-1174
    • Abdool Karim, Q.1    Abdool Karim, S.S.2    Frohlich, J.A.3
  • 8
    • 73349094086 scopus 로고    scopus 로고
    • Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
    • Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, et al. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N Engl J Med. 2009;361:2209-2220.
    • (2009) N Engl J Med. , vol.361 , pp. 2209-2220
    • Rerks-Ngarm, S.1    Pitisuttithum, P.2    Nitayaphan, S.3
  • 9
    • 13944254982 scopus 로고    scopus 로고
    • Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection
    • Flynn NM, Forthal DN, Harro CD, et al. Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection. J Infect Dis. 2005;191:654-665.
    • (2005) J Infect Dis. , vol.191 , pp. 654-665
    • Flynn, N.M.1    Forthal, D.N.2    Harro, C.D.3
  • 10
    • 33845433434 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand
    • Pitisuttithum P, Gilbert P, Gurwith M, et al. Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand. J Infect Dis. 2006;194:1661-1671.
    • (2006) J Infect Dis. , vol.194 , pp. 1661-1671
    • Pitisuttithum, P.1    Gilbert, P.2    Gurwith, M.3
  • 11
    • 56649105122 scopus 로고    scopus 로고
    • Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomised, placebo-controlled, test-of-concept trial
    • Buchbinder SP, Mehrotra DV, Duerr A, et al. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial. Lancet. 2008;372:1881-1893.
    • (2008) Lancet. , vol.372 , pp. 1881-1893
    • Buchbinder, S.P.1    Mehrotra, D.V.2    Duerr, A.3
  • 12
    • 84880223419 scopus 로고    scopus 로고
    • STATEMENT: NIH Discontinues Immunizations in HIV Vaccine Study Accessed 30 April, 2013
    • STATEMENT: NIH Discontinues Immunizations in HIV Vaccine Study. Available at: http://www.niaid.nih.gov/news/newsreleases/2013/Pages/HVTN505April2013. aspx. Accessed 30 April, 2013.
  • 13
    • 45249108765 scopus 로고    scopus 로고
    • Effect of acyclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: A randomised, double-blind, placebo-controlled trial
    • Celum C, Wald A, Hughes J, et al. Effect of acyclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial. Lancet. 2008;371:2109-2119.
    • (2008) Lancet. , vol.371 , pp. 2109-2119
    • Celum, C.1    Wald, A.2    Hughes, J.3
  • 14
    • 76149129743 scopus 로고    scopus 로고
    • Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2
    • Celum C, Wald A, Lingappa JR, et al. Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2. N Engl J Med. 2010;362:427-439.
    • (2010) N Engl J Med. , vol.362 , pp. 427-439
    • Celum, C.1    Wald, A.2    Lingappa, J.R.3
  • 15
    • 84864507852 scopus 로고    scopus 로고
    • Preexposure prophylaxis for HIV infection among African women
    • Van Damme L, Corneli A, Ahmed K, et al. Preexposure prophylaxis for HIV infection among African women. N Engl J Med. 2012;367:411-422.
    • (2012) N Engl J Med. , vol.367 , pp. 411-422
    • Van Damme, L.1    Corneli, A.2    Ahmed, K.3
  • 16
    • 84880217175 scopus 로고    scopus 로고
    • Microbicide Trials Network Accessed July 25, 2012
    • Microbicide Trials Network. VOICE (MTN-003). 2012; Available at: http://www.mtnstopshiv.org/news/studies/mtn003. Accessed July 25, 2012.
    • (2012) VOICE (MTN-003).
  • 17
    • 84864289978 scopus 로고    scopus 로고
    • Sexual risk behaviors, circumcision status, and preexisting immunity to adenovirus type 5 among men who have sex with men participating in a randomized HIV-1 vaccine efficacy trial: Step study
    • Koblin BA, Mayer KH, Noonan E, et al. Sexual risk behaviors, circumcision status, and preexisting immunity to adenovirus type 5 among men who have sex with men participating in a randomized HIV-1 vaccine efficacy trial: step study. J Acquir Immune Defic Syndr. 2012;60:405-413.
    • (2012) J Acquir Immune Defic Syndr. , vol.60 , pp. 405-413
    • Koblin, B.A.1    Mayer, K.H.2    Noonan, E.3
  • 18
    • 84860014826 scopus 로고    scopus 로고
    • Unraveling the divergent results of pre-exposure prophylaxis trials for HIV prevention
    • van der Straten A, Van Damme L, Haberer JE, et al. Unraveling the divergent results of pre-exposure prophylaxis trials for HIV prevention. AIDS. 2012;26:F13-F19.
    • (2012) AIDS , vol.26
    • Van Der Straten, A.1    Van Damme, L.2    Haberer, J.E.3
  • 19
    • 80053602998 scopus 로고    scopus 로고
    • Conceptual framework for behavioral and social science in HIV vaccine clinical research
    • Lau CY, Swann EM, Singh S, et al. Conceptual framework for behavioral and social science in HIV vaccine clinical research. Vaccine. 2011; 29:7794-7800.
    • (2011) Vaccine. , vol.29 , pp. 7794-7800
    • Lau, C.Y.1    Swann, E.M.2    Singh, S.3
  • 20
    • 0000268883 scopus 로고
    • Cognitive processes used by survey respondents to answer behavioral frequency questions
    • Blair E, Burton S. Cognitive processes used by survey respondents to answer behavioral frequency questions. J Consumer Res. 1987;14: 280-288.
    • (1987) J Consumer Res. , vol.14 , pp. 280-288
    • Blair, E.1    Burton, S.2
  • 22
    • 66949117525 scopus 로고    scopus 로고
    • How race becomes biology: Embodiment of social inequality
    • Gravlee CC. How race becomes biology: embodiment of social inequality. Am J Phys Anthropol. 2009;139:47-57.
    • (2009) Am J Phys Anthropol. , vol.139 , pp. 47-57
    • Gravlee, C.C.1
  • 24
    • 44949221619 scopus 로고    scopus 로고
    • Adolescent and adult participation in an HIV vaccine trial preparedness cohort in South Africa
    • Middelkoop K, Myer L, Mark D, et al. Adolescent and adult participation in an HIV vaccine trial preparedness cohort in South Africa. J Adolesc Health. 2008;43:8-14.
    • (2008) J Adolesc Health. , vol.43 , pp. 8-14
    • Middelkoop, K.1    Myer, L.2    Mark, D.3
  • 25
    • 62849111059 scopus 로고    scopus 로고
    • HIV incidence rates and risk factors for urban women in Zambia: Preparing for a microbicide clinical trial
    • Kapina M, Reid C, Roman K, et al. HIV incidence rates and risk factors for urban women in Zambia: preparing for a microbicide clinical trial. Sex Transm Dis. 2009;36:129-133.
    • (2009) Sex Transm Dis. , vol.36 , pp. 129-133
    • Kapina, M.1    Reid, C.2    Roman, K.3
  • 26
    • 0035313574 scopus 로고    scopus 로고
    • Are US populations appropriate for trials of human immunodeficiency virus vaccine? the HIVNET Vaccine Preparedness Study
    • Seage GR III, Holte SE, Metzger D, et al. Are US populations appropriate for trials of human immunodeficiency virus vaccine? The HIVNET Vaccine Preparedness Study. Am J Epidemiol. 2001;153:619-627.
    • (2001) Am J Epidemiol. , vol.153 , pp. 619-627
    • Seage III, G.R.1    Holte, S.E.2    Metzger, D.3
  • 27
    • 80052323519 scopus 로고    scopus 로고
    • HIV incidence and risk factors for acquisition in HIV discordant couples in Masaka Uganda: An HIV vaccine preparedness study
    • Ruzagira E, Wandiembe S, Abaasa A, et al. HIV incidence and risk factors for acquisition in HIV discordant couples in Masaka, Uganda: an HIV vaccine preparedness study. PLoS One. 2011;6:e24037.
    • (2011) PLoS One. , vol.6
    • Ruzagira, E.1    Wandiembe, S.2    Abaasa, A.3
  • 28
    • 42649124923 scopus 로고    scopus 로고
    • The HVTN protocol 903 vaccine preparedness study: Lessons learned in preparation for HIV vaccine efficacy trials
    • Djomand G, Metch B, Zorrilla CD, et al. The HVTN protocol 903 vaccine preparedness study: lessons learned in preparation for HIV vaccine efficacy trials. J Acquir Immune Defic Syndr. 2008;48:82-89.
    • (2008) J Acquir Immune Defic Syndr. , vol.48 , pp. 82-89
    • Djomand, G.1    Metch, B.2    Zorrilla, C.D.3
  • 29
    • 7144253781 scopus 로고    scopus 로고
    • Readiness of high-risk populations in the HIV Network for Prevention Trials to participate in HIV vaccine efficacy trials in the United States
    • Koblin BA, Heagerty P, Sheon A, et al. Readiness of high-risk populations in the HIV Network for Prevention Trials to participate in HIV vaccine efficacy trials in the United States. AIDS. 1998;12:785-793.
    • (1998) AIDS , vol.12 , pp. 785-793
    • Koblin, B.A.1    Heagerty, P.2    Sheon, A.3
  • 30
    • 39049156467 scopus 로고    scopus 로고
    • The value of site preparedness studies for future implementation of phase 2/IIb/III HIV prevention trials: Experience from the HPTN 055 study
    • Ramjee G, Kapiga S, Weiss S, et al. The value of site preparedness studies for future implementation of phase 2/IIb/III HIV prevention trials: experience from the HPTN 055 study. J Acquir Immune Defic Syndr. 2008;47:93-100.
    • (2008) J Acquir Immune Defic Syndr. , vol.47 , pp. 93-100
    • Ramjee, G.1    Kapiga, S.2    Weiss, S.3
  • 31
    • 0037321668 scopus 로고    scopus 로고
    • Randomized, controlled evaluation of a prototype informed consent process for HIV vaccine efficacy trials
    • Coletti AS, Heagerty P, Sheon AR, et al. Randomized, controlled evaluation of a prototype informed consent process for HIV vaccine efficacy trials. J Acquir Immune Defic Syndr. 2003;32:161-169.
    • (2003) J Acquir Immune Defic Syndr. , vol.32 , pp. 161-169
    • Coletti, A.S.1    Heagerty, P.2    Sheon, A.R.3
  • 32
    • 2142705712 scopus 로고    scopus 로고
    • Determinants of enrollment in a preventive HIV vaccine trial: Hypothetical versus actual willingness and barriers to participation
    • Buchbinder SP, Metch B, Holte SE, et al. Determinants of enrollment in a preventive HIV vaccine trial: hypothetical versus actual willingness and barriers to participation. J Acquir Immune Defic Syndr. 2004;36:604-612.
    • (2004) J Acquir Immune Defic Syndr. , vol.36 , pp. 604-612
    • Buchbinder, S.P.1    Metch, B.2    Holte, S.E.3
  • 33
    • 41849087248 scopus 로고    scopus 로고
    • SAVVY vaginal gel (C31G) for prevention of HIV infection: A randomized controlled trial in Nigeria
    • Feldblum PJ, Adeiga A, Bakare R, et al. SAVVY vaginal gel (C31G) for prevention of HIV infection: a randomized controlled trial in Nigeria. PLoS One. 2008;3:e1474.
    • (2008) PLoS One. , vol.3
    • Feldblum, P.J.1    Adeiga, A.2    Bakare, R.3
  • 34
    • 44349126694 scopus 로고    scopus 로고
    • SAVVY (C31G) gel for prevention of HIV infection in women: A phase 3, double-blind, randomized, placebo-controlled trial in Ghana
    • Peterson L, Nanda K, Opoku BK, et al. SAVVY (C31G) gel for prevention of HIV infection in women: a phase 3, double-blind, randomized, placebo-controlled trial in Ghana. PLoS One. 2007;2:e1312.
    • (2007) PLoS One. , vol.2
    • Peterson, L.1    Nanda, K.2    Opoku, B.K.3
  • 36
    • 0037160763 scopus 로고    scopus 로고
    • Blinding in randomised trials: Hiding who got what
    • Schulz KF, Grimes DA. Blinding in randomised trials: hiding who got what. Lancet. 2002;359:696-700.
    • (2002) Lancet. , vol.359 , pp. 696-700
    • Schulz, K.F.1    Grimes, D.A.2
  • 37
    • 0037045587 scopus 로고    scopus 로고
    • Generation of allocation sequences in randomised trials: Chance, not choice
    • Schulz KF, Grimes DA. Generation of allocation sequences in randomised trials: chance, not choice. Lancet. 2002;359:515-519.
    • (2002) Lancet. , vol.359 , pp. 515-519
    • Schulz, K.F.1    Grimes, D.A.2
  • 38
    • 20944437246 scopus 로고    scopus 로고
    • HIV sexual risk behavior over 36 months of follow-up in the world's first HIV vaccine efficacy trial
    • Bartholow BN, Buchbinder S, Celum C, et al. HIV sexual risk behavior over 36 months of follow-up in the world's first HIV vaccine efficacy trial. J Acquir Immune Defic Syndr. 2005;39:90-101.
    • (2005) J Acquir Immune Defic Syndr. , vol.39 , pp. 90-101
    • Bartholow, B.N.1    Buchbinder, S.2    Celum, C.3
  • 39
    • 0037442221 scopus 로고    scopus 로고
    • Invited commentary: Condom effectiveness-will prostate-specific antigen shed new light on this perplexing problem?
    • Steiner MJ, Feldblum PJ, Padian N. Invited commentary: condom effectiveness-will prostate-specific antigen shed new light on this perplexing problem? Am J Epidemiol. 2003;157:298-300.
    • (2003) Am J Epidemiol. , vol.157 , pp. 298-300
    • Steiner, M.J.1    Feldblum, P.J.2    Padian, N.3
  • 40
    • 0030950911 scopus 로고    scopus 로고
    • Validity of self-reported sexual behaviors in adolescent women using biomarker outcomes
    • Orr DP, Fortenberry JD, Blythe MJ. Validity of self-reported sexual behaviors in adolescent women using biomarker outcomes. Sex Transm Dis. 1997;24:261-266.
    • (1997) Sex Transm Dis. , vol.24 , pp. 261-266
    • Orr, D.P.1    Fortenberry, J.D.2    Blythe, M.J.3
  • 41
    • 84880193745 scopus 로고    scopus 로고
    • In search of the holy grail: Improving assessments of sexual activity in population surveys through collecting biomarkers of semen exposure
    • Accessed January 24, 2012
    • Kulczycki A. In search of the holy grail: improving assessments of sexual activity in population surveys through collecting biomarkers of semen exposure. Population Association of America 2010. Available at: http://paa2010.princeton. edu/download.aspx?submissionId=101743. Accessed January 24, 2012.
    • (2010) Population Association of America
    • Kulczycki, A.1
  • 42
    • 0032824722 scopus 로고    scopus 로고
    • Evaluation of prostate-specific antigen (PSA) membrane test assays for the forensic identification of seminal fluid
    • Hochmeister MN, Budowle B, Rudin O, et al. Evaluation of prostate-specific antigen (PSA) membrane test assays for the forensic identification of seminal fluid. J Forensic Sci. 1999;44:1057-1060.
    • (1999) J Forensic Sci. , vol.44 , pp. 1057-1060
    • Hochmeister, M.N.1    Budowle, B.2    Rudin, O.3
  • 43
    • 62849114743 scopus 로고    scopus 로고
    • Biomarkers of semen exposure
    • Mauck CK. Biomarkers of semen exposure. Sex Transm Dis. 2009;36(3 suppl):S81-S83.
    • (2009) Sex Transm Dis. , vol.36 , Issue.3 SUPPL.
    • Mauck, C.K.1
  • 44
    • 84862764447 scopus 로고    scopus 로고
    • Risk behaviour and time as covariates for efficacy of the HIV vaccine regimen ALVAC-HIV (vCP1521) and AIDSVAX B/E: A post-hoc analysis of the Thai phase 3 efficacy trial RV 144
    • Robb ML, Rerks-Ngarm S, Nitayaphan S, et al. Risk behaviour and time as covariates for efficacy of the HIV vaccine regimen ALVAC-HIV (vCP1521) and AIDSVAX B/E: a post-hoc analysis of the Thai phase 3 efficacy trial RV 144. Lancet Infect Dis. 2012;12:531-537.
    • (2012) Lancet Infect Dis. , vol.12 , pp. 531-537
    • Robb, M.L.1    Rerks-Ngarm, S.2    Nitayaphan, S.3
  • 45
    • 84880192830 scopus 로고    scopus 로고
    • Adherence and acceptability in MTN 001: A randomized cross-over trial of daily oral and topical tenofovir for HIV prevention in women
    • Minnis AM, Gandham S, Richardson BA, et al. Adherence and acceptability in MTN 001: a randomized cross-over trial of daily oral and topical tenofovir for HIV prevention in women. AIDS Behav. 2013;17:737-747.
    • (2013) AIDS Behav. , vol.17 , pp. 737-747
    • Minnis, A.M.1    Gandham, S.2    Richardson, B.A.3
  • 46
    • 79952277560 scopus 로고    scopus 로고
    • Real-time adherence monitoring for HIV antiretroviral therapy
    • Haberer JE, Kahane J, Kigozi I, et al. Real-time adherence monitoring for HIV antiretroviral therapy. AIDS Behav. 2010;14:1340-1346.
    • (2010) AIDS Behav. , vol.14 , pp. 1340-1346
    • Haberer, J.E.1    Kahane, J.2    Kigozi, I.3


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