Hybrid scaffolds composed of chitosan-PLGA-PEO nanofibers and PLGA microfibers for artificial skin

Tissue Engineering and Regenerative Medicine

Volumn 8, Issue SUPPL.2, 2011, Pages 108-115

  Lim, Hyun Ju ^a,b   Kim, Cheol Joo ^c   Oh, Eun Jung ^a,d   Kim, Tae Jung ^a   Jung, So Yeon ^a   Choi, Jin Hyun ^b,d   Lee, Weon Ju ^a   Kwon, Oh Hyeong ^c   Chung, Ho Yun ^a,b  

^a Kyungpook National University School of Medicine   (South Korea)

^b Kyungpook National University Hospital   (South Korea)

^c Kumoh National Institute of Technology   (South Korea)

^d Kyungpook National University   (South Korea)

Author keywords

Artificial skin; Dermal sheath cells; Hybrid scaffold; Micro fiber; Nano fiber

Indexed keywords

ARTIFICIAL SKIN; CELL SEEDING; ETHYLENE OXIDES; HAIR FOLLICLES; HYBRID SCAFFOLDS; MICRO-FIBER; SELF-REPAIR; SHEATH CELLS;

ARTIFICIAL ORGANS; CELL ADHESION; CHITOSAN; COPOLYMERS; HYDROPHILICITY; NANOFIBERS; REPAIR; SCANNING ELECTRON MICROSCOPY; STEM CELLS;

SCAFFOLDS (BIOLOGY);

EID: 84880180130     PISSN: 17382696     EISSN: 22125469     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. MO Back, SH Kim, JW So, et al., Fabrication and characterization of PLGA scaffold penetrated with demineralized bone solution, Tissue Eng Regen Med, 5, 229 (2008).
2. S Dumitriy, HWT Matthew, Polymeric biomaterials 2nd Ed., Marcel Dekker, 167 (2002).
3. JA Hibbell, Biomaterials in tissue engineering, Bio/Technol, 33, 165 (1995).
4. JY Lim, SH Kim, SW Park, et al., Regeneration of biodisk using annulus fibrousus and nucleus pulposus cell on PLGA/DBP hybrid scaffold, Tissue Eng Regen Med, 5, 96 (2008).
5. DV Heimburg, S Zachariah, I Heschel, et al., Human preadipocytes seeded on freeze-dried collagen scaffolds investigated in vitro and in vivo, Biomaterials, 22, 429 (2001).
6. ZG Tang, RA Black, JM Curran, et al., Surface properties and biocompatibility of solvent-cast poly(ε-caprolactone) film, Biomaterials, 25, 4741 (2004).
7. Y Wang, X Shi, L Ren, et al., Porous poly(lactic-co-glycolide) microsphere sintered scaffolds for tissue repair applications, Mat Sci Eng C-Bio S, 29, 2502 (2009).
8. Q Cai, J Yang, JBS Wang, A novel porous cells scaffold made of polylactide-dextran blend by combining phase-separation and particle-leaching techniques, Biomaterials, 23, 4483 (2002).
9. JM Singelyn, JA DeQuach, SB Seif-Naraghi, et al., Naturally delivered myocardical matrix as an injectable scaffold for cardiac tissue engineering, Biomaterials, 30, 5409 (2009).
10. WJ Li, J Jiang, RS Tuan, Chondrocyte phenotype in engineered fibrous matrix is regulated by fiber size, Tissue Eng, 12, 1775 (2006).
11. JE Sanders, CE Stiles, CL Hayes, Tissue response to singlepolymer fibers of varying diameters: evaluation of fibrous encapsulation and macrophase density, J Biomed Mater Res, 52, 231 (2000).
12. Y Takahashi, Y Tabata, Effect of the fiber diameter and porosity of non-woven PET fabrics on the osteogenic differentiation of mesenchymal stem cells, J Biomed Sci Polym Ed, 15, 41 (2004).
13. TJ Webster, RW Siegel, R Bizios, Osteoblast adhesion on nanophase ceramics, Biomaterials, 20, 1221 (1999).
14. TJ Webster, C Ergun, RH Doremus et al, Enhanced functions of osteoblasts on nanophase ceramics, Biomaterials, 21, 1803 (2000).
15. ZM Huang, Micromechanical strength formular of unidirectional composites, Mater Lett, 40, 164 (1999).
16. IM Maria, TC Marjana, Epidermal stem cell: the cradle of epidermal determinations, differentiation and wound healing, Biol Cell, 97, 173 (2005).
17. SY Park, MH Kwack, EJ Chung, et al., Establishment of SV40T-transformed human dermal papilla cells and identification of dihydrotestosterone-regulated genes by cDNA microarray, J Dermatol Sci, 47, 201 (2007).
18. AJ Reynolds, C Lawrence, PB Cserhalmi, et al., Trans-gender induction of hair follicles, Nature, 402, 33 (1999).
19. B Havlickova, T Biro, A Mescalchin, et al., Towards optimization of an organotypic assay system that imitates human hair follicle-like epithelial-mesenchymal interations, Br J Dermal, 151, 753 (2004).
20. CC Yang, G Cotsarelis, Review of hair follicle dermal cells, J Dermato Sci, 57, 2 (2010).
21. CP Narnes, SA Sell, ED Boland, et al., Nanofibers technology: designing the next generation of tissue engineering scaffolds, Adv Drug Deliver Rev, 59, 1413 (2009).
22. N Bhattarai, Z Li, J Gunn, et al., Natural-synthetic polyblend nanofibers for biomedical applications, Adv Mater, 21, 1 (2009).
23. MS Bae, SI Jeong, SE Kim, et al., Nanofibers scaffold for tissue regeneration using electrospinning method, Tissue Eng Regen Med, 5, 196 (2008).
24. JY Choi, KY Jung, JS Lee, et al., Fabrication and in vitro evaluation of the electrospun small diameter vascular grafts composed of elastin/PLGA/PCL and heparin-VEGF, Tissue Eng Regen Med, 7, 149 (2010).
25. JA Matthews, GE Wnek, DG Simpson, et al., Electrospinning of collagen nanofibers, Biomacromolecules, 3, 232 (2002).
26. ER Kenawy, JM Layman, JR Watkins, et al., Electrospinning of poly(ethylene-co-vinyl alcohol) fibers, Biomaterials, 24, 907 (2003).
27. L Huang, RP Apkarian, EL Chaikof, High-resolution analysis of engineering type I collagen nanofibers by electron microscopy, Scanning, 22, 372 (2001).
28. GS Khang, JM Lee, SJ Lee, et al., Polymer-cell interaction, Tissue Eng Regen Med, 17, 297 (2002).
29. CA Jahoda, AJ Reynolds, C Chaponnier, et al., Smooth muscle alpha-actin is a marker for hair follicle dermis in vivo and in vitro, J Cell Sci, 99, 627 (1991).
30. Y Ito, TS Hamazaki, K Ohnuma, et al., Isolation of murine hair-inducing cells using the cell surface marker prominin-1/CD133, J Invest Dermatol, 127, 1052 (2007).