Serum β2-microglobulin level is a useful indicator of disease activity and hemophagocytic syndrome complication in systemic lupus erythematosus and adult-onset Still's disease

Clinical Rheumatology

Volumn 32, Issue 7, 2013, Pages 999-1005

  Wakabayashi, Kuninobu ^a   Inokuma, Shigeko ^a   Matsubara, Erika ^a   Onishi, Kae ^a   Asashima, Hiromitsu ^a   Nakachi, Shinichiro ^a   Hagiwara, Kiyofumi ^a  

^a JAPANESE RED CROSS MEDICAL CENTER   (Japan)

Author keywords

2 microglobulin; Adult onset Still's disease (AOSD); Hemophagocytic lymphohistiocytosis (HLH); Hemophagocytic syndrome (HPS); Macrophage activation syndrome (MAS); Systemic lupus erythematosus (SLE)

Indexed keywords

ACETYLSALICYLIC ACID; BETA 2 MICROGLOBULIN; CYCLOSPORIN A; D DIMER; FIBRINOGEN DEGRADATION PRODUCT; IBUPROFEN; IMMUNOGLOBULIN; LACTATE DEHYDROGENASE; METHYLPREDNISOLONE; PREDNISOLONE;

ADULT; BLOOD ANALYSIS; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE ACTIVITY; FEMALE; FERRITIN BLOOD LEVEL; HEMOPHAGOCYTIC SYNDROME; HOSPITAL PATIENT; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; LABORATORY TEST; LACTATE DEHYDROGENASE BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADOLESCENT; ADULT; AGED; AUTOIMMUNITY; BETA 2-MICROGLOBULIN; BIOLOGICAL MARKERS; FEMALE; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MACROPHAGE ACTIVATION SYNDROME; MIDDLE AGED; STILL'S DISEASE, ADULT-ONSET; YOUNG ADULT;

EID: 84880159297     PISSN: 07703198     EISSN: 14349949     Source Type: Journal    
DOI: 10.1007/s10067-013-2220-8     Document Type: Conference Paper

References (35)

1. Bethea M, Forman DT (1990) Beta 2-microglobulin: its significance and clinical usefulness. Ann Clin Lab Sci 20(3):163-168 (Pubitemid 20160912)
2. Maury CP, Helve T, Sjoblom C (1982) Serum beta 2-microglobulin, sialic acid, and C-reactive protein in systemic lupus erythematosus. Rheumatol Int 2(4):145-149 (Pubitemid 13179919)
3. Evrin PE, Strom T (1984) Beta 2-microglobulin and its binding activity in serum from patients with SLE. Ann Rheum Dis 43(2):267-274 (Pubitemid 14172576)
4. Yeung CK, Wong KL, Wong WS, Chan KH (1986) Beta 2-microglobulin and systemic lupus erythematosus. J Rheumatol 13(6):1053-1058
5. Font J, Coca A, Molina R, Ballesta A, Cardellach F, Ingelmo M, Balague A, Balcells A (1986) Serum beta 2-microglobulin as a marker of activity in systemic lupus erythematosus. Scand J Rheumatol 15(2):201-205 (Pubitemid 16048723)
6. Kim HA, Jeon JY, Yoon JM, Suh CH (2010) Beta 2-microglobulin can be a disease activity marker in systemic lupus erythematosus. Am J Med Sci 339(4):337-340
7. Castro J, Jimenez-Alonso J, Sabio JM, Rivera-Civico F, Martin-Armada M, Rodriguez MA, Jaimez L, Castillo MJ, Sanchez-Roman J (2003) Salivary and serum beta2-microglobulin and gamma-glutamyl-transferase in patients with primary Sjogren syndrome and Sjogren syndrome secondary to systemic lupus erythematosus. Clin Chim Acta 334(1-2):225-231 (Pubitemid 36836079)
8. Imashuku S (1997) Differential diagnosis of hemophagocytic syndrome: underlying disorders and selection of the most effective treatment. Int J Hematol 66(2):135-151 (Pubitemid 27360177)
9. Ramanan AV, Schneider R (2003) Macrophage activation syndrome-what's in a name! J Rheumatol 30(12):2513-2516
10. Kumakura S, Ishikura H, Kondo M, Murakawa Y, Masuda J, Kobayashi S (2004) Autoimmune-associated hemophagocytic syndrome. Mod Rheumatol 14(3):205-215 (Pubitemid 39206664)
11. Hochberg MC (1997) Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 40(9):1725
12. Yamaguchi M, Ohta A, Tsunematsu T, Kasukawa R, Mizushima Y, Kashiwagi H, Kashiwazaki S, Tanimoto K, Matsumoto Y, Ota T et al (1992) Preliminary criteria for classification of adult Still's disease. J Rheumatol 19(3):424-430
13. Tsuda H (1997) Hemophagocytic syndrome (HPS) in children and adults. Int J Hematol 65(3):215-226 (Pubitemid 27154169)
14. Matsuo S, Imai E, Horio M, Yasuda Y, Tomita K, Nitta K, Yamagata K, Tomino Y, Yokoyama H, Hishida A (2009) Revised equations for estimated GFR from serum creatinine in Japan. Am J Kidney Dis 53(6):982-992
15. Cooper EH, Plesner T (1980) Beta-2-microglobulin review: its relevance in clinical oncology. Med Pediatr Oncol 8(4):323-334 (Pubitemid 11138381)
16. Bianchi C, Donadio C, Tramonti G, Consani C, Lorusso P, Rossi G (2001) Reappraisal of serum beta2-microglobulin as marker of GFR. Ren Fail 23(3-4):419-429 (Pubitemid 32692277)
17. Kaito K, Kobayashi M, Katayama T, Otsubo H, Ogasawara Y, Sekita T, Saeki A, Sakamoto M, Nishiwaki K, Masuoka H, Shimada T, Yoshida M, Hosoya T (1997) Prognostic factors of hemophagocytic syndrome in adults: analysis of 34 cases. Eur J Haematol 59(4):247-253 (Pubitemid 27425467)
18. Maruyama J, Inokuma S (2010) Cytokine profiles of macrophage activation syndrome associated with rheumatic diseases. J Rheumatol 37(5):967-973
19. Hibi S, Ikushima S, Fujiwara F, Hashida T, Tsunamoto K, Todo S, Imashuku S (1995) Serum and urine beta-2-microglobulin in hemophagocytic syndrome. Cancer 75(7):1700-1705
20. Onishi S, Ikenoya K, Matsumoto K, Kamata Y, Nagashima T, Kamimura T, Iwamoto M, Minota S (2008) Urinary beta2-microglobulin as a sensitive marker for haemophagocytic syndrome associated with collagen vascular diseases. Rheumatology (Oxford) 47(11):1730-1732
21. Larroche C, Mouthon L (2004) Pathogenesis of hemophagocytic syndrome (HPS). Autoimmun Rev 3(2):69-75 (Pubitemid 38293367)
22. Osugi Y, Hara J, Tagawa S, Takai K, Hosoi G, Matsuda Y, Ohta H, Fujisaki H, Kobayashi M, Sakata N, Kawa-Ha K, Okada S, Tawa A (1997) Cytokine production regulating Th1 and Th2 cytokines in hemophagocytic lymphohistiocytosis. Blood 89(11):4100-4103 (Pubitemid 27220957)
23. Takada H, Nomura A, Ohga S, Hara T (2001) Interleukin-18 in hemophagocytic lymphohistiocytosis. Leuk Lymphoma 42(1-2):21-28 (Pubitemid 32700919)
24. Jordan MB, Hildeman D, Kappler J, Marrack P (2004) An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood 104(3):735-743 (Pubitemid 38970567)
25. Kereveur A, McIlroy D, Samri A, Oksenhendler E, Clauvel JP, Autran B (1999) Up-regulation of adhesion and MHC molecules on splenic monocyte/macrophages in adult haemophagocytic syndrome. Br J Haematol 104(4):871-877 (Pubitemid 29143511)
26. Barcy S, Wettendorff M, Leo O, Urbain J, Kruger M, Ceuppens JL, de Boer M (1995) FcR cross-linking on monocytes results in impaired T cell stimulatory capacity. Int Immunol 7(2):179-189
27. Arlet JB, Le TH, Marinho A, Amoura Z, Wechsler B, Papo T, Piette JC (2006) Reactive haemophagocytic syndrome in adult-onset Still's disease: a report of six patients and a review of the literature. Ann Rheum Dis 65(12):1596-1601 (Pubitemid 44799671)
28. Wong KF, Hui PK, Chan JK, Chan YW, Ha SY (1991) The acute lupus hemophagocytic syndrome. Ann Intern Med 114(5):387-390
29. Lambotte O, Khellaf M, Harmouche H, Bader-Meunier B, Manceron V, Goujard C, Amoura Z, Godeau B, Piette JC, Delfraissy JF (2006) Characteristics and long-term outcome of 15 episodes of systemic lupus erythematosus-associated hemophagocytic syndrome. Medicine (Baltimore) 85(3):169-182 (Pubitemid 43833015)
30. Fukaya S, Yasuda S, Hashimoto T, Oku K, Kataoka H, Horita T, Atsumi T, Koike T (2008) Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases: analysis of 30 cases. Rheumatology (Oxford) 47(11):1686-1691
31. Henter JI, Horne A, Arico M, Egeler RM, Filipovich AH, Imashuku S, Ladisch S, McClain K, Webb D, Winiarski J, Janka G (2007) HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 48(2):124-131 (Pubitemid 44958267)
32. Ravelli A, Magni-Manzoni S, Pistorio A, Besana C, Foti T, Ruperto N, Viola S, Martini A (2005) Preliminary diagnostic guidelines for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis. J Pediatr 146(5):598-604 (Pubitemid 40616243)
33. Davi S, Consolaro A, Guseinova D, Pistorio A, Ruperto N, Martini A, Cron RQ, Ravelli A (2011) An international consensus survey of diagnostic criteria for macrophage activation syndrome in systemic juvenile idiopathic arthritis. J Rheumatol 38(4):764-768
34. Behrens EM, Beukelman T, Paessler M, Cron RQ (2007) Occult macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis. J Rheumatol 34(5):1133-1138 (Pubitemid 46774861)
35. Bleesing J, Prada A, Siegel DM, Villanueva J, Olson J, Ilowite NT, Brunner HI, Griffin T, Graham TB, Sherry DD, Passo MH, Ramanan AV, Filipovich A, Grom AA (2007) The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor alpha-chain in macrophage activation syndrome and untreated new-onset systemic juvenile idiopathic arthritis. Arthritis Rheum 56(3):965-971 (Pubitemid 46399444)