Myofiber prestretch magnitude determines regional systolic function during ectopic activation in the tachycardia-induced failing canine heart

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 305, Issue 2, 2013, Pages

  Howard, Elliot J ^a   Kerckhoffs, Roy C P ^a   Vincent, Kevin P ^a   Krishnamurthy, Adarsh ^a   Villongco, Christopher T ^a   Mulligan, Lawrence J ^c   McCulloch, Andrew D ^a   Omens, Jeffrey H ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c Therapy Delivery Systems Leads Research   (United States)

Author keywords

Epicardial pacing; Fiber strain; Heart failure; Prestretch; Wall thickening

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DOG; HEART FAILURE; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART PREEJECTION PERIOD; NONHUMAN; PRIORITY JOURNAL; SYSTOLE; TACHYCARDIA;

EPICARDIAL PACING; FIBER STRAIN; HEART FAILURE; PRESTRETCH; WALL THICKENING;

ANIMALS; BIOMECHANICS; CARDIAC PACING, ARTIFICIAL; DISEASE MODELS, ANIMAL; DOGS; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; FINITE ELEMENT ANALYSIS; HEART FAILURE; HEMODYNAMICS; MAGNETIC RESONANCE IMAGING; MODELS, CARDIOVASCULAR; MYOCARDIAL CONTRACTION; MYOCARDIUM; STROKE VOLUME; SYSTOLE; TACHYCARDIA, VENTRICULAR; TIME FACTORS; VENTRICULAR FUNCTION, LEFT; VENTRICULAR PRESSURE;

EID: 84880157583     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00186.2012     Document Type: Article

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