Transcranial magnetic stimulation has no placebo effect on motor learning

Clinical Neurophysiology

Volumn 124, Issue 8, 2013, Pages 1646-1651

  Jelić, Milan B ^a   Stevanović, Vuk B ^a   Milanović, Sladjan D ^a   Ljubisavljević, Miloš R ^a,b   Filipović, Saša R ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

Brain plasticity; Motor learning; Neurorehabilitation; Placebo; Purdue pegboard; Transcranial magnetic stimulation

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; LEARNING; MALE; MOTOR ACTIVITY; PLACEBO EFFECT; PRIORITY JOURNAL; TASK PERFORMANCE; THETA RHYTHM; TRANSCRANIAL MAGNETIC STIMULATION;

BRAIN PLASTICITY; MOTOR LEARNING; NEUROREHABILITATION; PLACEBO; PURDUE PEGBOARD; TRANSCRANIAL MAGNETIC STIMULATION;

ADULT; FEMALE; HUMANS; LEARNING; MALE; MOTOR CORTEX; PLACEBO EFFECT; PSYCHOMOTOR PERFORMANCE; TRANSCRANIAL MAGNETIC STIMULATION; YOUNG ADULT;

EID: 84880156287     PISSN: 13882457     EISSN: 18728952     Source Type: Journal    
DOI: 10.1016/j.clinph.2013.02.024     Document Type: Article

References (33)

1. Agostino R., Iezzi E., Dinapoli L., Gilio F., Conte A., Mari F., et al. Effects of 5Hz subthreshold magnetic stimulation of primary motor cortex on fast finger movements in normal subjects. Exp Brain Res 2007, 180:105-111.
2. Agostino R., Iezzi E., Dinapoli L., Suppa A., Conte A., Berardelli A. Effects of intermittent theta-burst stimulation on practice-related changes in fast finger movements in healthy subjects. Eur J Neurosci 2008, 28:822-828.
3. Baraduc P., Lang N., Rothwell J.C., Wolpert D.M. Consolidation of dynamic motor learning is not disrupted by rTMS of primary motor cortex. Curr Biol 2004, 14:252-256.
4. Benedetti F., Carlino E., Pollo A. How placebos change the patient's brain. Neuropsychopharmacology 2011, 36:339-354.
5. Brunoni A.R., Lopes M., Kaptchuk T.J., Fregni F. Placebo response of non-pharmacological and pharmacological trials in major depression: a systematic review and meta-analysis. PLoS One 2009, 4:e4824.
6. Colagiuri B., Boakes R.A. Perceived treatment, feedback, and placebo effects in double-blind RCTs: an experimental analysis. Psychopharmacology (Berl) 2010, 208:433-441.
7. Colagiuri B., Livesey E.J., Harris J.A. Can expectancies produce placebo effects for implicit learning?. Psychon Bull Rev 2011, 18:399-405.
8. Huang Y.Z., Edwards M.J., Rounis E., Bhatia K.P., Rothwell J.C. Theta burst stimulation of the human motor cortex. Neuron 2005, 45:201-206.
9. Hummel F.C., Celnik P., Pascual-Leone A., Fregni F., Byblow W.D., Buetefisch C.M., et al. Controversy: noninvasive and invasive cortical stimulation show efficacy in treating stroke patients. Brain Stimul 2008, 1:370-382.
10. Iezzi E., Suppa A., Conte A., Agostino R., Nardella A., Berardelli A. Theta-burst stimulation over primary motor cortex degrades early motor learning. Eur J Neurosci 2010, 31:585-592.
11. Jung P., Ziemann U. Homeostatic and nonhomeostatic modulation of learning in human motor cortex. J Neurosci 2009, 29:5597-5604.
12. Kaptchuk T.J., Goldman P., Stone D.A., Stason W.B. Do medical devices have enhanced placebo effects?. J Clin Epidemiol 2000, 53:786-792.
13. Kim Y.H., Park J.W., Ko M.H., Jang S.H., Lee P.K. Facilitative effect of high frequency subthreshold repetitive transcranial magnetic stimulation on complex sequential motor learning in humans. Neurosci Lett 2004, 367:181-185.
14. Ljubisavljevic M. Transcranial magnetic stimulation and the motor learning-associated cortical plasticity. Exp Brain Res 2006, 173:215-222.
15. Mansur C.G., Myczkowki M.L., de Barros C.S., Sartorelli M.C., Bellini B.B., Dias A.M., et al. Placebo effect after prefrontal magnetic stimulation in the treatment of resistant obsessive-compulsive disorder: a randomized controlled trial. Int J Neuropsychopharmacol 2011, 14:1389-1397.
16. McRae C., Cherin E., Yamazaki T.G., Diem G., Vo A.H., Russell D., et al. Effects of perceived treatment on quality of life and medical outcomes in a double-blind placebo surgery trial. Arch Gen Psychiatry 2004, 61:412-420.
17. Muellbacher W., Ziemann U., Wissel J., Dang N., Kofler M., Facchini S., et al. Early consolidation in human primary motor cortex. Nature 2002, 415:640-644.
18. Noguchi T., Demura S., Nagasawa Y., Uchiyama M. An examination of practice and laterality effects on the Purdue Pegboard and Moving Beans with Tweezers. Percept Mot Skills 2006, 102:265-274.
19. Oken B.S. Placebo effects: clinical aspects and neurobiology. Brain 2008, 131:2812-2823.
20. Oldfield R.C. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 1971, 9:97-113.
21. Pollo A., Benedetti F. The placebo response: neurobiological and clinical issues of neurological relevance. Prog Brain Res 2009, 175:283-294.
22. Pollo A., Carlino E., Benedetti F. Placebo mechanisms across different conditions: from the clinical setting to physical performance. Philos Trans R Soc Lond B Biol Sci 2011, 366:1790-1798.
23. Reis J., Swayne O.B., Vandermeeren Y., Camus M., Dimyan M.A., Harris-Love M., et al. Contribution of transcranial magnetic stimulation to the understanding of cortical mechanisms involved in motor control. J Physiol (Lond) 2008, 586:325-351.
24. Rossini P.M., Barker A.T., Berardelli A., Caramia M.D., Caruso G., Cracco R.Q., et al. Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application. Report of an IFCN committee. Electroencephalogr Clin Neurophysiol 1994, 91:79-92.
25. Schmidt R.A., Lee T.D. Motor learning. Motor control and learning: a behavior emphasis 2005, Human Kinetics, Champaign, IL, p. 301-20.
26. Sczesny-Kaiser M., Tegenthoff M., Schwenkreis P. Influence of 5Hz repetitive transcranial magnetic stimulation on motor learning. Neurosci Lett 2009, 457:71-74.
27. Strafella A.P., Ko J.H., Monchi O. Therapeutic application of transcranial magnetic stimulation in Parkinson's disease: the contribution of expectation. Neuroimage 2006, 31:1666-1672.
28. Tanaka S., Sandrini M., Cohen L.G. Modulation of motor learning and memory formation by non-invasive cortical stimulation of the primary motor cortex. Neuropsychol Rehabil 2011, 21:650-675.
29. Teo J.T., Swayne O.B., Cheeran B., Greenwood R.J., Rothwell J.C. Human theta burst stimulation enhances subsequent motor learning and increases performance variability. Cereb Cortex 2011, 21:1627-1638.
30. Verdino M., Dingman S. Two measures of laterality in handedness: the Edinburgh handedness inventory and the Purdue pegboard test of manual dexterity. Percept Mot Skills 1998, 86:476-478.
31. Wagner T., Valero-Cabre A., Pascual-Leone A. Noninvasive human brain stimulation. Annu Rev Biomed Eng 2007, 9:527-565.
32. Weiler F., Brandao P., Barros-Filho J., Uribe C.E., Pessoa V.F., Brasil-Neto J.P. Low frequency (0.5Hz) rTMS over the right (non-dominant) motor cortex does not affect ipsilateral hand performance in healthy humans. Arq Neuropsiquiatr 2008, 66:636-640.
33. Ziemann U., Paulus W., Nitsche M.A., Pascual-Leone A., Byblow W.D., Berardelli A., et al. Consensus: motor cortex plasticity protocols. Brain Stimul 2008, 1:164-182.