Immunohistochemical analysis of thrombi retrieved during treatment of acute ischemic stroke: Does stent-retriever cause intimal damage?

Stroke

Volumn 44, Issue 6, 2013, Pages 1720-1722

  Singh, Paramdeep ^a,b   Doostkam, Soroush ^a   Reinhard, Matthias ^a   Ivanovas, Vera ^a   Taschner, Christian A ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b GGS Medical College & Hospital Faridkot   (India)

Author keywords

Immunohistochemistry; Ischemic stroke; Thrombectomy; Thrombus

Indexed keywords

ALTEPLASE; CD24 ANTIGEN; CD34 ANTIBODY;

ADULT; AGED; ARTERY INJURY; ARTERY WALL; ARTICLE; BASILAR ARTERY OBSTRUCTION; BRAIN ISCHEMIA; CLINICAL ARTICLE; CONNECTIVE TISSUE; ENDOTHELIUM CELL; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTERNAL CAROTID ARTERY OCCLUSION; INTIMA; MALE; MECHANICAL THROMBECTOMY; OCCLUSIVE CEREBROVASCULAR DISEASE; OUTCOME ASSESSMENT; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PRIORITY JOURNAL; RECANALIZATION; STENT; STENT RETRIEVER; VERTEBRAL ARTERY STENOSIS;

IMMUNOHISTOCHEMISTRY; ISCHEMIC STROKE; THROMBECTOMY; THROMBUS;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD34; CEREBRAL ANGIOGRAPHY; ENDOTHELIAL CELLS; FEMALE; HUMANS; INTRACRANIAL THROMBOSIS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; STROKE; THROMBECTOMY; TREATMENT OUTCOME; TUNICA INTIMA;

EID: 84880149318     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.113.000964     Document Type: Article

References (12)

1. Hacke W, Donnan G, Fieschi C, Kaste M, von Kummer R, Broderick JP, et al.; ATLANTIS Trials Investigators; ECASS Trials Investigators; NINDS rt-PA Study Group Investigators. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet. 2004;363:768-774.
2. Saqqur M, Uchino K, Demchuk AM, Molina CA, Garami Z, Calleja S, et al.; CLOTBUST Investigators. Site of arterial occlusion identifed by transcranial Doppler predicts the response to intravenous thrombolysis for stroke. Stroke. 2007;38:948-954.
3. Koh JS, Lee SJ, Ryu CW, Kim HS. Safety and effcacy of mechanical thrombectomy with solitaire stent-retrieval for acute ischemic stroke. Neurointervention 2012;7:1-9.
4. Novakovic RL, Toth G, Narayanan S, Zaidat OO. Retrievable stents for endovascular acute ischemic stroke therapy. Neurology. 2012;79: 148-57.
5. Kurre W, Pérez MA, Horvath D, Schmid E, Bäzner H, Henkes H. Does mechanical thrombectomy in acute embolic stroke have long-term side effects on intracranial vessels? An angiographic follow-up study. Cardiovasc Intervent Radiol (epub ahead of print).
6. Costalat V, Machi P, Lobotesis K, Maldonado I, Vendrell JF, Riquelme C, et al. Rescue, combined, and stand-alone thrombectomy in the management of large vessel occlusion stroke using the solitaire device: a prospective 50-patient single-center study. Stroke. 2011;42:1929-1935.
7. Higashida RT, Furlan AJ, Roberts H, Tomsick T, Connors B, Barr J, et al.; Technology Assessment Committee of the American Society of Interventional and Therapeutic Neuroradiology; Technology Assessment Committee of the Society of Interventional Radiology. Trial design and reporting standards for intra-arterial cerebral thrombolysis for acute ischemic stroke. Stroke. 2003;34:e109-e137.
8. Marder VJ, Chute DJ, Starkman S, Abolian AM, Kidwell C, Liebeskind D, et al. Analysis of thrombi retrieved from cerebral arteries of patients with acute ischemic stroke. Stroke. 2006;37:2086-2093.
9. Almekhlaf MA, Hu WY, Hill MD, Auer RN. Calcifcation and endothelialization of thrombi in acute stroke. Ann Neurol. 2008;64: 344-348.
10. Liebeskind DS, Sanossian N, Yong WH, Starkman S, Tsang MP, Moya AL, et al. CT and MRI early vessel signs refect clot composition in acute stroke. Stroke. 2011;42:1237-1243.
11. Chueh JY, Wakhloo AK, Hendricks GH, Silva CF, Weaver JP, Gounis MJ. Mechanical characterization of thromboemboli in acute isch-emic stroke and laboratory embolus analogs. AJNR Am J Neuroradiol. 2011;32:1237-1244.
12. Nogueira RG, Levy EI, Gounis M, Siddiqui AH. The Trevo device: pre-clinical data of a novel stroke thrombectomy device in two different animal models of arterial thrombo-occlusive disease. J Neurointerv Surg. 2012;4:295-300.