STAT4 and T-bet are required for the plasticity of IFN-γ expression across Th2 ontogeny and influence changes in Ifng promoter DNA methylation

Journal of Immunology

Volumn 191, Issue 2, 2013, Pages 678-687

  Williams, Christopher L ^a,b   Schilling, Marcia M ^a,b   Cho, Sung Hoon ^a,b   Lee, Keunwook ^a,b   Wei, Mei ^a,b   Aditi, ^a,b   Boothby, Mark ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GAMMA INTERFERON; STAT4 PROTEIN; TRANSCRIPTION FACTOR T BET;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EFFECTOR CELL; EPIGENETIC REPRESSION; GENE; GENE EXPRESSION; GENE LOSS; IFNG GENE; IMMUNOLOGICAL MEMORY; INTERFERON PRODUCTION; INTRACELLULAR SIGNALING; LYMPHOCYTE FUNCTION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; ONTOGENY; POLARIZATION; PRIORITY JOURNAL; PROMOTER REGION; TH1 CELL; TH2 CELL;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CPG ISLANDS; DNA METHYLATION; IMMUNOLOGIC MEMORY; INTERFERON-GAMMA; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MICE, NUDE; PROMOTER REGIONS, GENETIC; STAT4 TRANSCRIPTION FACTOR; T-BOX DOMAIN PROTEINS; TH1 CELLS; TH2 CELLS;

EID: 84880119702     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1203360     Document Type: Article

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