Risk factors for BK virus infection in the era of therapeutic drug monitoring

Transplantation

Volumn 95, Issue 12, 2013, Pages 1498-1505

  Borni Duval, Claire ^a   Caillard, Sophie ^a   Olagne, Jérôme ^a   Perrin, Peggy ^a   Braun Parvez, Laura ^a   Heibel, Françoise ^a   Moulin, Bruno ^a  

^a UNIVERSITY HOSPITAL OF STRASBOURG   (France)

Author keywords

BK virus nephropathy; Kidney transplantation; Mycophenolate mofetil; Tacrolimus; Therapeutic drug monitoring

Indexed keywords

CYCLOSPORIN A; EVEROLIMUS; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PANEL REACTIVE ANTIBODY; RAPAMYCIN; STEROID; TACROLIMUS; THYMOCYTE ANTIBODY;

ACUTE GRAFT REJECTION; ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BK VIRUS INFECTION; BLOOD SAMPLING; COLD ISCHEMIA; CONTROLLED STUDY; CYTOMEGALOVIRUS; DELAYED GRAFT FUNCTION; DISEASE ASSOCIATION; DOSE RESPONSE; DRUG DOSE REDUCTION; DRUG MONITORING; FEMALE; GRAFT RECIPIENT; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFECTION RISK; KIDNEY BIOPSY; KIDNEY DISEASE; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; URINALYSIS; VIREMIA;

ADOLESCENT; ADULT; AGED; AREA UNDER CURVE; BIOPSY; BK VIRUS; DRUG MONITORING; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; MYCOPHENOLIC ACID; POLYOMAVIRUS INFECTIONS; RENAL INSUFFICIENCY; RISK FACTORS; STEROIDS; TACROLIMUS; VIREMIA; YOUNG ADULT;

EID: 84880094832     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e3182921995     Document Type: Article

References (38)

1. Purighalla R, Shapiro R, McCauley J, et al. BKvirus infection in a kidney allograft diagnosed by needle biopsy. Am J Kidney Dis 1995; 26: 671.
2. Binet I. Polyomavirus disease under new immunosuppressive drugs: a cause of renal graft dysfunction and graft loss. Transplantation 1999; 67: 918.
3. Howell DN, Smith SR, Butterly DW, et al. Diagnosis and management of BK polyomavirus interstitial nephritis in renal transplant recipients. Transplantation 1999; 68: 1279.
4. Randhawa PS, Finkelstein S, Scantlebury V, et al. Human polyoma virus-associated interstitial nephritis in the allograft kidney. Transplantation 1999; 67: 103.
5. Brennan DC, Agha I, Bohl DL, et al. Incidence of BK with tacrolimus versus cyclosporine and impact of preemptive immunosuppression reduction. Am J Transplant 2005; 5: 582.
6. Bressollette-Bodin C, Coste-Burel M, Hourmant M, et al. A prospective longitudinal study of BK virus infection in 104 renal transplant recipients. Am J Transplant 2005; 5: 1926.
7. Ramos E, Drachenberg CB, Wali R, et al. The decade of polyomavirus BK-associated nephropathy: state of affairs. Transplantation 2009; 87: 621.
8. Hirsch HH, Brennan DC, Drachenberg CB, et al. Polyomavirus-associated nephropathy in renal transplantation: interdisciplinary analyses and recommendations. Transplantation 2005; 79: 1277.
9. Drachenberg CB, Hirsch HH, Papadimitriou JC, et al. Polyomavirus BK versus JC replication and nephropathy in renal transplant recipients: a prospective evaluation. Transplantation 2007; 84: 323.
10. Randhawa P, Ho A, Shapiro R, et al. Correlates of quantitative measurement of BK polyomavirus (BKV) DNA with clinical course of BKV infection in renal transplant patients. J Clin Microbiol 2004; 42: 1176.
11. Ramos E. Clinical course of polyoma virus nephropathy in 67 renal transplant patients. J Am Soc Nephrol 2002; 13: 2145.
12. Bohl DL, Storch GA, Ryschkewitsch C, et al. Donor origin of BK virus in renal transplantation and role of HLA C7 in susceptibility to sustained BK viremia. Am J Transplant 2005; 5: 2213.
13. Hirsch HH, Knowles W, Dickenmann M, et al. Prospective study of polyomavirus type BK replication and nephropathy in renal-transplant recipients. N Engl J Med 2002; 347: 488.
14. Shah KV. Human polyomavirus BKV and renal disease. Nephrol Dial Transplant 2000; 15: 754.
15. Nickeleit V, Hirsch HH, Zeiler M, et al. BK-virus nephropathy in renal transplantsVtubular necrosis, MHC-class II expression and rejection in a puzzling game. Nephrol Dial Transplant 2000; 15: 324.
16. Adawalla Y. HLA mismatching increases the risk of BK virus ne-phropathy in renal transplant recipients. Am J Transpl 2004; 4: 1691.
17. Mengel M. Incidence of polyomavirus-nephropathy in renal allo-grafts: influence of modern immunosuppressive drugs. Nephrol Dial Transplant 2003; 18: 1190.
18. White LH, Casian A, Hilton R, et al. BK virus nephropathy in renal transplant patients in London. Transplantation 2008; 85: 1008.
19. Randhawa P, Brennan DC. BK virus infection in transplant recipients: an overview and update. Am J Transplant 2006; 6: 2000.
20. Hurault de Ligny B, Etienne I, Francois A, et al. Polyomavirus-induced acute tubulo-interstitial nephritis in renal allograft recipients. Transplant Proc 2000; 32: 2760.
21. Hirsch H. Prospective monitoring of BK virus load after discontinuing sirolimus treatment in a renal transplant patient with BK virus nephropathy. J Infect Dis 2001; 184: 1494.
22. Lipshutz GS, Flechner SM, Govani MV, et al. BK nephropathy in kidney transplant recipients treated with a calcineurin inhibitor-free immunosuppression regimen. Am J Transplant 2004; 4: 2132.
23. Dharnidharka VR, Cherikh WS, Abbott KC. An OPTN analysis of national registry data on treatment of BK virus allograft nephropathy in the United States. Transplantation 2009; 87: 1019.
24. Smith JM, Dharnidharka VR, Talley L, et al. BK virus nephropathy in pediatric renal transplant recipients: an analysis of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS) registry. Clin J Am Soc Nephrol 2007; 2: 1037.
25. Trofe J. Polyomavirus in kidney and kidney-pancreas transplantation: a defined protocol for immunosuppression reduction and histologic monitoring. Transpl Proc 2002; 34: 1788.
26. Manitpisitkul W, Drachenberg C, Ramos E, et al. Maintenance immunosuppressive agents as risk factors for BK virus nephropathy: a case-control study. Transplantation 2009; 88: 83.
27. Vasudev B, Hariharan S, Hussain SA, et al. BK virus nephritis: risk factors, timing, and outcome in renal transplant recipients. Kidney Int 2005; 68: 1834.
28. Ginevri F, Azzi A, Hirsch HH, et al. Prospective monitoring of polyomavirus BK replication and impact of pre-emptive intervention in pediatric kidney recipients. Am J Transplant 2007; 7: 2727.
29. Schold JD, Rehman S, Kayle LK, et al. Treatment for BK virus: incidence, risk factors and outcomes for kidney transplant recipients in the United States. Transpl Int 2009; 22: 626.
30. Cherikh WS, Kauffman HM, McBride MA, et al. Association of the type of induction immunosuppression with posttransplant lympho-proliferative disorder, graft survival, and patient survival after primary kidney transplantation. Transplantation 2003; 76: 1289.
31. Ali AM, Gibson IW, Birk P, et al. Pretransplant serologic testing to identify the risk of polyoma BKviremia in pediatric kidney transplant recipients. Pediatr Transplant 2011; 15: 827.
32. Dadhania D, Snopkowski C, Ding R, et al. Epidemiology of BK virus in renal allograft recipients: independent risk factors for BK virus replication. Transplantation 2008; 86: 521.
33. Koukoulaki M, Grispou E, Pistolas D, et al. Prospective monitoring of BK virus replication in renal transplant recipients. Transpl Infect Dis 2009; 11: 1.
34. Cosio FG. Comparison of low versus high tacrolimus levels in kidney transplantation: assessment of efficacy by protocol biopsies. Transplantation 2007; 83: 411.
35. Knight SR. Does the evidence support the use of mycophenolate mofetil therapeutic drug monitoring in clinical practice? A systematic review. Transplantation 2008; 85: 1675.
36. LeMeur Y. Individualized mycophenolate mofetil dosing based on drug exposure significantly improves patient outcomes after renal transplantation. Am J Transpl 2007; 7: 2496.
37. Fafi-Kremer S. Evaluation of the Epstein-Barr virus R-Gene Quantification Kit in whole blood with different extraction methods and PCR platforms. J Mol Diagn 2008; 10: 78.
38. Drachenberg CB, Hirsch HH, Ramos E, et al. Polyomavirus disease in renal transplantation: review of pathological findings and diagnostic methods. Hum Pathol 2005; 36: 1245.