Efficacy of oral iron therapy in improving the developmental outcome of pre-school children with non-anaemic iron deficiency: A systematic review

Public Health Nutrition

Volumn 16, Issue 8, 2013, Pages 1497-1506

  Abdullah, Kawsari ^a,b   Kendzerska, Tetyana ^b   Shah, Prakesh ^b,c   Uleryk, Elizabeth ^a   Parkin, Patricia C ^a,b,d  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

Author keywords

Child development; Non anaemic iron deficiency; Pre school children

Indexed keywords

BLOOD; HUMAN; INFANT; IRON DEFICIENCY ANEMIA; IRON INTAKE; OBSERVATIONAL STUDY; PRESCHOOL CHILD; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; TREATMENT OUTCOME; ADMINISTRATION AND DOSAGE; ANEMIA, IRON-DEFICIENCY;

ANEMIA, IRON-DEFICIENCY; CHILD, PRESCHOOL; HUMANS; INFANT; IRON, DIETARY; OBSERVATIONAL STUDY AS TOPIC; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TREATMENT OUTCOME;

IRON INTAKE;

EID: 84880080636     PISSN: 13689800     EISSN: 14752727     Source Type: Journal    
DOI: 10.1017/S1368980012003709     Document Type: Review

References (30)

1. Tulchinsky TH & Vatavikova EA (2009) The New Public Health, 2nd ed. Burlington, MA: Elsevier Academic Press.
2. World Health Organization/UNICEF/United Nations University (2001) Iron Deficiency Anaemia: Assessment, Prevention, and Control. A Guide for Programme Managers (WHO/NHD/01.3). Geneva: WHO.
3. Yager JY & Hartfield DS (2002) Neurologic manifestations of iron deficiency in childhood. Pediatr Neurol 27, 85-92.
4. Lozoff B, Beard J, Connor J et al. (2006) Long-lasting neural and behavioral effects of iron deficiency in infancy. Nutr Rev 64, 5 Pt 2, S34-S43.
5. Grantham-McGregor S & Ani C (2001) A review of studies on the effect of iron deficiency on cognitive development in children. J Nutr 131, 2 Suppl. 2, 649S-668S.
6. Logan S, Martins S & Gilbert RE (2001) Iron therapy for improving psychomotor development andcognitive function in children under the age of three with iron deficiency anaemia. Cochrane Database Syst Rev issue 2, CD001444.
7. Lozoff B, Brittenham GM, Wolf AW et al. (1987) Iron deficiency anemia and iron therapy effects on infant developmental test performance. Pediatrics 79, 981-995.
8. Pollitt E, Saco-Pollitt C, Leibel RL et al. (1986) Iron deficiency and behavioral development in infants and preschool children. Am J Clin Nutr 43, 555-565.
9. Soewondo S, Husaini M & Pollitt E (1989) Effects of iron deficiency on attention and learning processes in preschool children: Bandung, Indonesia. Am J Clin Nutr 50, 3 Suppl., 667-674.
10. Scrimshaw N (1990) Functional significance of iron deficiency: an overview. In Annual Nutrition Workshop Series. vol III: Functional Significance of Iron Deficiency, pp. 1-13 [CO Enwonwu, editor]. Nashville, TN: Meharry Medical College.
11. Otero GA, Aguirre DM, Porcayo R et al. (1999) Psychological and electroencephalographic study in school children with iron deficiency. Int J Neurosci 99, 113-121.
12. Baker RD & Greer FR (2010) Diagnosis and prevention of iron deficiency and iron-deficiency anemia in infants and young children (0-3 years of age). Pediatrics 126, 1040-1050.
13. Owen GM, Lubin AH & Garry PJ (1971) Preschool children in the United States: who has iron deficiency? J Pediatr 79, 563-568.
14. de Andraca I, Walter T, Castillo M et al. (1990) Iron deficiency anemia and its effects upon psychological development at preschool age: a longitudinal study. In Nestlé Foundation Annual Report, 1990, pp. 53-62. Lausanne: Nestlé Foundation.
15. Lozoff B, Jimenez E & Wolf AW (1991) Long-term developmental outcome of infants with iron deficiency. N Engl J Med 325, 687-694.
16. Ramdath DD, Simeon DT, Wong MS et al. (1995) Iron status of schoolchildren with varying intensities of Trichuris trichiura infection. Parasitology 110, 347-351.
17. Lane PA, Nuss R & Ambruso DR (2001) Hematologic disorder. In Current Pediatric Diagnosis & Treatment, 15th ed., vol. 26, pp. 748-749. [WWHay, AR Hayward, MJ Levin et al., editors]. Beijing: People's Medical Publishing House.
18. Mora J (2002) Iron supplementation: overcoming technical and practical barriers. J Nutr 132, 4 Suppl., 853S-855S.
19. Bridges KR & Person HA (2003) Iron deficiency. In Rudolph's Pediatrics, 21st ed., vol. 19.3.1, section 23, part 2, pp. 431-432 [CD Rudolph and AM Rudolph editors]. Beijing: People's Medical Publishing House.
20. Fairbanks VF & Beutler E (2001) Iron deficiency. In Williams Hematology, 16th ed., vol. 38, pp. 447-470 [E Beutler, MA Lichtman, BS Coller et al., editors]. Beijing: People's Medical Publication House.
21. Galloway R & McGuire J (1994) Determinants of compliance with iron supplementation: supplies, side effects or psychology? Soc Sci Med 39, 381-390.
22. Sheard N (1994) Iron deficiency and infant development. Nutr Rev 52, 137-146.
23. Stoltzfus R (2001) Defining iron-deficiency anemia in public health terms: a time for reflection. J Nutr 131, 2 Suppl. 2, 565S-567S.
24. Lichtenberger E (2005) General measure of cognition for the pre-school child. Ment Retard Dev Disabil Res Rev 11, 197-208.
25. Higgins JPT & Green S (editors) (2011) Cochrane Handbook for Systematic Reviews of Interventions, Version 5.1.0. The Cochrane Collaboration. http://www.cochrane-handbook.org (accessed August 2012).
26. Wells GA, Shea B, O'Connell D et al. (2000) The Newcastle- Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. http://www.ohri.ca/programs/clinical-epidemiology/oxford.asp (accessed August 2012).
27. Idjradinata P & Pollitt E (1993) Reversal of developmental delays in iron deficient anaemic infants treated with iron. Lancet 341, 1-4.
28. Akman M, Cebeci D, Okur V et al. (2004) The effects of iron deficiency on infants' developmental test performance. Acta Paediatr 93, 1391-1396.
29. Kazal L (2002) Prevention of iron deficiency in infants and toddlers. Am Fam Physician 66, 1217-1224.
30. Szajewska H, Ruszczynski M & Chmielewska A (2010) Effects of iron supplementation in nonanemic pregnant women, infants, and young children on the mental performance and psychomotor development of children: a systematic review of randomized controlled trials. Am J Clin Nutr 91, 1684-1690.