Outcomes of morbidly obese patients receiving invasive mechanical ventilation: A nationwide analysis

Chest

Volumn 144, Issue 1, 2013, Pages 48-54

  Kumar, Gagan ^a   Majumdar, Tilottama ^a   Jacobs, Elizabeth R ^a,b   Danesh, Valerie ^c   Dagar, Gaurav ^a   Deshmukh, Abhishek ^d   Taneja, Amit ^a   Nanchal, Rahul ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c ORLANDO REGIONAL MEDICAL CENTER   (United States)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; ARTIFICIAL VENTILATION; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HIGH RISK POPULATION; HOSPITALIZATION; HUMAN; ICD-9; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORBID OBESITY; MORTALITY; ORGAN INJURY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RESPIRATORY FAILURE; THERAPY EFFECT; TRACHEOSTOMY; TREATMENT DURATION;

EID: 84880057124     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.12-2310     Document Type: Article

References (30)

1. Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999-2008. JAMA. 2010; 303 (3): 235-241.
2. Ray DE, Matchett SC, Baker K, Wasser T, Young MJ. The effect of body mass index on patient outcomes in a medical ICU. Chest. 2005; 127 (6): 2125-2131.
3. Bercault N, Boulain T, Kuteifan K, Wolf M, Runge I, Fleury JC. Obesity-related excess mortality rate in an adult intensive care unit: a risk-adjusted matched cohort study. Crit Care Med. 2004; 32 (4): 998-1003.
4. Yaegashi M, Jean R, Zuriqat M, Noack S, Homel P. Outcome of morbid obesity in the intensive care unit. J Intensive Care Med. 2005; 20 (3): 147-154.
5. Akinnusi ME, Pineda LA, El Solh AA. Effect of obesity on intensive care morbidity and mortality: a meta-analysis. Crit Care Med. 2008; 36 (1): 151-158.
6. Hogue CW Jr, Stearns JD, Colantuoni E, et al. The impact of obesity on outcomes after critical illness: a meta-analysis. Intensive Care Med. 2009; 35 (7): 1152-1170.
7. Oliveros H, Villamor E. Obesity and mortality in critically ill adults: a systematic review and meta-analysis. Obesity (Silver Spring). 2008; 16 (3): 515-521.
8. Duarte AG, Justino E, Bigler T, Grady J. Outcomes of morbidly obese patients requiring mechanical ventilation for acute respiratory failure. Crit Care Med. 2007; 35 (3): 732-737.
9. Martino JL, Stapleton RD, Wang M, et al. Extreme obesity and outcomes in critically ill patients. Chest. 2011; 140 (5): 1198-1206.
10. Frat JP, Gissot V, Ragot S, et al; Association des Réanimateurs du Centre-Ouest (ARCO) study group. Impact of obesity in mechanically ventilated patients: a prospective study. Intensive Care Med. 2008; 34 (11): 1991-1998.
11. Salome CM, King GG, Berend N. Physiology of obesity and effects on lung function. J Appl Physiol. 2010; 108 (1): 206-211.
12. Morris AE, Stapleton RD, Rubenfeld GD, Hudson LD, Caldwell E, Steinberg KP. The association between body mass index and clinical outcomes in acute lung injury. Chest. 2007; 131 (2): 342-348.
13. Anzueto A, Frutos-Vivar F, Esteban A, et al; Ventila group. Influence of body mass index on outcome of the mechanically ventilated patients. Thorax. 2011; 66 (1): 66-73.
14. Gong MN, Bajwa EK, Thompson BT, Christiani DC. Body mass index is associated with the development of acute respiratory distress syndrome. Thorax. 2010; 65 (1): 44-50.
15. Pelosi P, Croci M, Ravagnan I, et al. The effects of body mass on lung volumes, respiratory mechanics, and gas exchange during general anesthesia. Anesth Analg. 1998; 87( 3): 654-660.
16. Kress JP, Pohlman AS, Alverdy J, Hall JB. The impact of morbid obesity on oxygen cost of breathing (VO(2RESP)) at rest. Am J Respir Crit Care Med. 1999; 160 (3): 883-886.
17. Wang Y, Beydoun MA, Liang L, Caballero B, Kumanyika SK. Will all Americans become overweight or obese? Estimating the progression and cost of the US obesity epidemic. Obesity (Silver Spring). 2008; 16 (10): 2323-2330.
18. Healthcare Cost and Utilization Project. Introduction to the HCUP Nationwide Inpatient Sample (NIS) 2008. Healthcare Cost and Utilization Project website. http://www.hcup-us. ahrq.gov/db/nation/nis/NIS-Introduction-2008.jsp. Accessed October 26, 2011.
19. Quan H, Parsons GA, Ghali WA. Validity of procedure codes in International Classification of Diseases, 9th revision, clinical modification administrative data. Med Care. 2004; 42 (8): 801-809.
20. Hutter MM, Randall S, Khuri SF, et al. Laparoscopic versus open gastric bypass for morbid obesity: a multicenter, prospective, risk-adjusted analysis from the National Surgical Qual ity Improvement Program. Ann Surg 2006; 243 (5): 657-662.
21. Memtsoudis SG, Bombardieri AM, Ma Y, Walz JM, Chiu YL, Mazumdar M. Mortality of patients with respiratory insufficiency and adult respiratory distress syndrome after surgery: the obesity paradox. J Intensive Care Med. 2012; 27 (5): 306-311.
22. Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol. 1992; 45 (6): 613-619.
23. Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med. 2003; 348 (16): 1546-1554.
24. Lewandowski K, Lewandowski M. Intensive care in the obese. Best Pract Res Clin Anaesthesiol. 2011; 25 (1): 95-108.
25. Baskerville JR, Moore RK. Morbidly obese patients receive delayed ED care: body mass index greater than 40 kg/m2 have longer disposition times. Am J Emerg Med. 2012; 30 (5): 737-740.
26. Choi JC, Bakaeen FG, Cornwell LD, et al. Morbid obesity is associated with increased resource utilization in coronary artery bypass grafting. Ann Thorac Surg. 2012; 94 (1): 23-28.
27. O'Brien JM Jr, Philips GS, Ali NA, Aberegg SK, Marsh CB, Lemeshow S. The association between body mass index, processes of care, and outcomes from mechanical ventilation: a prospective cohort study. Crit Care Med. 2012; 40 (5): 1456-1463.
28. O'Brien JM Jr, Phillips GS, Ali NA, Lucarelli M, Marsh CB, Lemeshow S. Body mass index is independently associated with hospital mortality in mechanically ventilated adults with acute lung injury. Crit Care Med. 2006; 34 (3): 738-744.
29. Paolini JB, Mancini J, Genestal M, et al. Predictive value of abdominal obesity vs. body mass index for determining risk of intensive care unit mortality. Crit Care Med. 2010; 38 (5): 1308-1314.
30. Adams KF, Schatzkin A, Harris TB, et al. Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. N Engl J Med. 2006; 355 (8): 763-778.