메뉴 건너뛰기




Volumn 190, Issue 2, 2013, Pages 799-806

Avanafil, a highly selective phosphodiesterase type 5 inhibitor for erectile dysfunction, shows good safety profiles for retinal function and hemodynamics in anesthetized dogs

Author keywords

avanafil; erectile dysfunction; hypotension; penis; retina

Indexed keywords

AVANAFIL; GLYCERYL TRINITRATE; SILDENAFIL;

EID: 84880040137     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2013.01.017     Document Type: Article
Times cited : (9)

References (25)
  • 1
    • 0024848484 scopus 로고
    • Physiological role of cGMP and cGMP-dependent protein kinase in the cardiovascular system
    • U. Walter Physiological role of cGMP and cGMP-dependent protein kinase in the cardiovascular system Rev Physiol Biochem Pharmacol 113 1989 41
    • (1989) Rev Physiol Biochem Pharmacol , vol.113 , pp. 41
    • Walter, U.1
  • 3
    • 0027404913 scopus 로고
    • Intracellular cyclic GMP receptor proteins
    • T.M. Lincoln, T.L. Cornwell Intracellular cyclic GMP receptor proteins FASEB J 7 1993 328
    • (1993) FASEB J , vol.7 , pp. 328
    • Lincoln, T.M.1    Cornwell, T.L.2
  • 4
    • 0042859823 scopus 로고    scopus 로고
    • Cyclic GMP phosphodiesterases and regulation of smooth muscle function
    • S.D. Rybalkin, C. Yan, K.E. Bornfeldt Cyclic GMP phosphodiesterases and regulation of smooth muscle function Circ Res 93 2003 280
    • (2003) Circ Res , vol.93 , pp. 280
    • Rybalkin, S.D.1    Yan, C.2    Bornfeldt, K.E.3
  • 5
    • 79955664087 scopus 로고    scopus 로고
    • Mammalian cyclic nucleotide phosphodiesterases: Molecular mechanisms and physiological functions
    • S.H. Francis, M.A. Blount, J.D. Corbin Mammalian cyclic nucleotide phosphodiesterases: molecular mechanisms and physiological functions Physiol Rev 91 2011 651
    • (2011) Physiol Rev , vol.91 , pp. 651
    • Francis, S.H.1    Blount, M.A.2    Corbin, J.D.3
  • 6
    • 33748743368 scopus 로고    scopus 로고
    • Expression, distribution and regulation of phosphodiesterase 5
    • C.S. Lin, G. Lin, Z.C. Xin Expression, distribution and regulation of phosphodiesterase 5 Curr Pharm Des 12 2006 3439
    • (2006) Curr Pharm des , vol.12 , pp. 3439
    • Lin, C.S.1    Lin, G.2    Xin, Z.C.3
  • 7
    • 33847068206 scopus 로고    scopus 로고
    • Overview of PDEs and their regulation
    • K. Omori, J. Kotera Overview of PDEs and their regulation Circ Res 100 2007 309
    • (2007) Circ Res , vol.100 , pp. 309
    • Omori, K.1    Kotera, J.2
  • 8
    • 0033838119 scopus 로고    scopus 로고
    • Potentiation of penile tumescence by T-1032, a new potent and specific phosphodiesterase type v inhibitor, in dogs
    • T. Noto, H. Inoue, T. Ikeo Potentiation of penile tumescence by T-1032, a new potent and specific phosphodiesterase type V inhibitor, in dogs J Pharmacol Exp Ther 294 2000 870
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 870
    • Noto, T.1    Inoue, H.2    Ikeo, T.3
  • 10
    • 84863720636 scopus 로고    scopus 로고
    • Avanafil, a potent and highly selective phosphodiesterase-5 inhibitor for erectile dysfunction
    • J. Kotera, H. Mochida, H. Inoue Avanafil, a potent and highly selective phosphodiesterase-5 inhibitor for erectile dysfunction J Urol 188 2012 668
    • (2012) J Urol , vol.188 , pp. 668
    • Kotera, J.1    Mochida, H.2    Inoue, H.3
  • 11
    • 0033927440 scopus 로고    scopus 로고
    • Sildenafil citrate potentiates the hypotensive effects of nitric oxide donor drugs in male patients with stable angina
    • D.J. Webb, G.J. Muirhead, M. Wulff Sildenafil citrate potentiates the hypotensive effects of nitric oxide donor drugs in male patients with stable angina J Am Coll Cardiol 36 2000 25
    • (2000) J Am Coll Cardiol , vol.36 , pp. 25
    • Webb, D.J.1    Muirhead, G.J.2    Wulff, M.3
  • 12
    • 0242552045 scopus 로고    scopus 로고
    • Time course of the interaction between tadalafil and nitrates
    • R.A. Kloner, A.M. Hutter, J.T. Emmick Time course of the interaction between tadalafil and nitrates J Am Coll Cardiol 42 2003 1855
    • (2003) J Am Coll Cardiol , vol.42 , pp. 1855
    • Kloner, R.A.1    Hutter, A.M.2    Emmick, J.T.3
  • 13
    • 3342991544 scopus 로고    scopus 로고
    • Potency, selectivity, and consequences of nonselectivity of PDE inhibition
    • E. Bischoff Potency, selectivity, and consequences of nonselectivity of PDE inhibition Int J Impot Res 16 suppl 2004 S11
    • (2004) Int J Impot Res , vol.16 , Issue.SUPPL. , pp. 11
    • Bischoff, E.1
  • 14
    • 27244459472 scopus 로고    scopus 로고
    • Efficacy and selectivity of phosphodiesterase-targeted drugs in inhibiting photoreceptor phosphodiesterase (PDE6) in retinal photoreceptors
    • X. Zhang, Q. Feng, R.H. Cote Efficacy and selectivity of phosphodiesterase-targeted drugs in inhibiting photoreceptor phosphodiesterase (PDE6) in retinal photoreceptors Invest Ophthalmol Vis Sci 46 2005 3060
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 3060
    • Zhang, X.1    Feng, Q.2    Cote, R.H.3
  • 15
    • 1642497572 scopus 로고    scopus 로고
    • T-0156, a novel phosphodiesterase type 5 inhibitor, and sildenafil have different pharmacological effects on penile tumescence and electroretinogram in dogs
    • H. Mochida, T. Noto, H. Inoue T-0156, a novel phosphodiesterase type 5 inhibitor, and sildenafil have different pharmacological effects on penile tumescence and electroretinogram in dogs Eur J Pharmacol 485 2004 283
    • (2004) Eur J Pharmacol , vol.485 , pp. 283
    • Mochida, H.1    Noto, T.2    Inoue, H.3
  • 16
    • 0031886174 scopus 로고    scopus 로고
    • Cardiovascular effect of a new 1,5-benzothiazepine derivative TA-993 in anesthetized dogs
    • M. Kaburaki, H. Narita, H. Yabana Cardiovascular effect of a new 1,5-benzothiazepine derivative TA-993 in anesthetized dogs J Cardiovasc Pharmacol 31 1998 240
    • (1998) J Cardiovasc Pharmacol , vol.31 , pp. 240
    • Kaburaki, M.1    Narita, H.2    Yabana, H.3
  • 17
    • 0023878367 scopus 로고
    • Cardiovascular effects of a new 1,5-benzothiazepine calcium antagonist in anesthetized dogs
    • S. Murata, K. Kikkawa, H. Yabana Cardiovascular effects of a new 1,5-benzothiazepine calcium antagonist in anesthetized dogs Arzneimittelforschung 38 1988 521
    • (1988) Arzneimittelforschung , vol.38 , pp. 521
    • Murata, S.1    Kikkawa, K.2    Yabana, H.3
  • 18
    • 72449123274 scopus 로고    scopus 로고
    • Safety of sildenafil citrate: Review of 67 double-blind placebo-controlled trials and the postmarketing safety database
    • F. Giuliano, G. Jackson, F. Montorsi Safety of sildenafil citrate: review of 67 double-blind placebo-controlled trials and the postmarketing safety database Int J Clin Pract 64 2010 240
    • (2010) Int J Clin Pract , vol.64 , pp. 240
    • Giuliano, F.1    Jackson, G.2    Montorsi, F.3
  • 19
    • 84864502944 scopus 로고    scopus 로고
    • Selectivity of avanafil, a PDE5 inhibitor for the treatment of erectile dysfunction: Implications for clinical safety and improved tolerability
    • R. Wang, A.L. Burnett, W.H. Heller Selectivity of avanafil, a PDE5 inhibitor for the treatment of erectile dysfunction: Implications for clinical safety and improved tolerability J Sex Med 9 2012 2122
    • (2012) J Sex Med , vol.9 , pp. 2122
    • Wang, R.1    Burnett, A.L.2    Heller, W.H.3
  • 20
    • 84866429366 scopus 로고    scopus 로고
    • Avanafil for the treatment of erectile dysfunction: A multicenter, randomized, double-blind study in men with diabetes mellitus
    • I. Goldstein, L.A. Jones, L.H. Belkoff Avanafil for the treatment of erectile dysfunction: a multicenter, randomized, double-blind study in men with diabetes mellitus Mayo Clin Proc 87 2012 843
    • (2012) Mayo Clin Proc , vol.87 , pp. 843
    • Goldstein, I.1    Jones, L.A.2    Belkoff, L.H.3
  • 21
    • 58149345209 scopus 로고    scopus 로고
    • Vision disorders and phosphodiesterase type 5 inhibitors: A review of the evidence to date
    • A.M. Laties Vision disorders and phosphodiesterase type 5 inhibitors: a review of the evidence to date Drug Saf 32 2009 1
    • (2009) Drug Saf , vol.32 , pp. 1
    • Laties, A.M.1
  • 22
    • 33748746141 scopus 로고    scopus 로고
    • Cardiovascular effects of phosphodiesterase 5 inhibitors
    • T. Reffelmann, R.A. Kloner Cardiovascular effects of phosphodiesterase 5 inhibitors Curr Pharmacol Des 12 2006 3485
    • (2006) Curr Pharmacol des , vol.12 , pp. 3485
    • Reffelmann, T.1    Kloner, R.A.2
  • 23
    • 0037023496 scopus 로고    scopus 로고
    • Sildenafil and T-1032, phosphodiesterase type 5 inhibitors, showed a different vasorelaxant property in the isolated rat aorta
    • H. Mochida, H. Inoue, M. Takagi Sildenafil and T-1032, phosphodiesterase type 5 inhibitors, showed a different vasorelaxant property in the isolated rat aorta Eur J Pharmacol 440 2002 45
    • (2002) Eur J Pharmacol , vol.440 , pp. 45
    • Mochida, H.1    Inoue, H.2    Takagi, M.3
  • 24
    • 85172623823 scopus 로고    scopus 로고
    • Highlights of Prescribing Information. Revised April 2012. Reference ID: 3123097. Silver Spring: United States Food and Drug Administration, United States Department of Health and Human Services 2012
    • Highlights of Prescribing Information. Revised April 2012. Reference ID: 3123097. Silver Spring: United States Food and Drug Administration, United States Department of Health and Human Services 2012.
  • 25
    • 85172630506 scopus 로고    scopus 로고
    • Hemodynamic effects of co-administration of avanafil and glyceryl trinitrate
    • November 17-20, New York, New York; abstract 112
    • Nehra A, Swearingen D, Dietrich J, et al. Hemodynamic effects of co-administration of avanafil and glyceryl trinitrate. Presented at meeting of Sexual Medicine Society of North America, November 17-20, 2005, New York, New York; abstract 112.
    • (2005) Meeting of Sexual Medicine Society of North America
    • Nehra, A.1    Swearingen, D.2    Dietrich, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.