Adult prescription drug use and pediatric medication exposures and poisonings

Pediatrics

Volumn 132, Issue 1, 2013, Pages 18-27

  Burghardt, Lindsey C ^a,b   Ayers, John W ^c   Brownstein, John S ^a,b   Bronstein, Alvin C ^d   Ewald, Michele Burns ^a,b   Bourgeois, Florence T ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c SAN DIEGO STATE UNIVERSITY   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

Drug therapy; Epidemiology; Poisoning; Prescription drugs; Prevention and control

Indexed keywords

ANTILIPEMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; OPIATE; ORAL ANTIDIABETIC AGENT; PRESCRIPTION DRUG;

ADOLESCENT; ADULT; ARTICLE; CHILD; DISEASE ASSOCIATION; DRUG EXPOSURE; DRUG INTOXICATION; DRUG USE; EMERGENCY WARD; HEALTH CARE UTILIZATION; HOSPITALIZATION; HUMAN; INFANT; INJURY SEVERITY; MAJOR CLINICAL STUDY; MEDICAL INFORMATION SYSTEM; PRESCHOOL CHILD; PRIORITY JOURNAL; RISK ASSESSMENT; SCHOOL CHILD; TIME SERIES ANALYSIS;

DRUG THERAPY; EPIDEMIOLOGY; POISONING; PRESCRIPTION DRUGS; PREVENTION AND CONTROL;

ADOLESCENT; ADRENERGIC BETA-ANTAGONISTS; ADULT; AGE FACTORS; ANALGESICS, OPIOID; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; DRUG UTILIZATION; FEMALE; HUMANS; HYPOGLYCEMIC AGENTS; HYPOLIPIDEMIC AGENTS; INFANT; MALE; POISON CONTROL CENTERS; PRESCRIPTION DRUGS; RISK FACTORS; UNITED STATES;

EID: 84879984384     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2012-2978     Document Type: Article

References (37)

1. Bronstein AC, Spyker DA, Cantilena LR Jr, Green JL, Rumack BH, Giffin SL. 2009 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 27th Annual Report. Clin Toxicol (Phila). 2010;48(10):979-1178
2. Lifshitz M, Gavrilov V. Acute poisoning in children. Isr Med Assoc J. 2000;2(7):504-506
3. Olguin HJ, Garduño LB, Pérez JF, Pérez CF. Unintentional poisoning with drugs in a Mexican pediatric population. J Popul Ther Clin Pharmacol. 2011;18:e156-e160
4. Shannon M. Ingestion of toxic substances by children. N Engl J Med. 2000;342(3):186-191
5. Riordan M, Rylance G, Berry K. Poisoning in children 2: Painkillers. Arch Dis Child. 2002; 87(5):397-399
6. Budnitz DS, Salis S. Preventing medication overdoses in young children: An opportunity for harm elimination. Pediatrics. 2011; 127(6). Available at: Www.pediatrics.org/cgi/content/full/127/6/e1597
7. Bond GR, Woodward RW, Ho M. The growing impact of pediatric pharmaceutical poisoning. J Pediatr. 2012;160(2):265-270.e1
8. Franklin RL, Rodgers GB. Unintentional child poisonings treated in United States hospital emergency departments: National estimates of incident cases, populationbased poisoning rates, and product involvement. Pediatrics. 2008;122(6):1244-1251
9. Rodgers GB, Franklin RL, Midgett JD. Unintentional paediatric ingestion poisonings and the role of imitative behaviour. Inj Prev. 2012;18(2):103-108
10. Schillie SF, Shehab N, Thomas KE, Budnitz DS. Medication overdoses leading to emergency department visits among children. Am J Prev Med. 2009;37(3):181-187
11. Bailey JE, Campagna E, Dart RC; RADARS System Poison Center Investigators. The underrecognized toll of prescription opioid abuse on young children. Ann Emerg Med. 2009;53(4):419-424
12. Bronstein AC, Spyker DA, Cantilena LR Jr, Green JL, Rumack BH, Giffin SL. 2008 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 26th Annual Report. Clin Toxicol (Phila). 2009;47(10):911-1084
13. Gu Q, Dillon CF, Burt VL. Prescription drug use continues to increase: U.S. prescription drug data for 2007-2008. NCHS Data Brief. 2010(42):1-8
14. National Ambulatory Medical Care Survey: NAMCS and NHAMCS Web Tables, 2009. Available at: Www.cdc.gov/nchs/data/ahcd/namcs-summary/2009-namcs-web- tables. pdf. Accessed January 7, 2013
15. National Ambulatory Medical Care Survey: NAMCS and NHAMCS Web Tables, 2008. www.cdc.gov/nchs/ahcd/web-tables.htm#2008. Accessed November 1, 2011
16. Copp HL, Shapiro DJ, Hersh AL. National ambulatory antibiotic prescribing patterns for pediatric urinary tract infection, 1998-2007. Pediatrics. 2011;127(6):1027-1033
17. Wisniewski AM, Purdy CH, Blondell RD. The epidemiologic association between opioid prescribing, non-medical use, and emergency department visits. J Addict Dis. 2008; 27(1):1-11
18. US Census Bureau. National intercensal estimates (1990-2000): Intercensal estimates of the United States population by age and sex, 1990-2000: All months. Available at: Www.census.gov/popest/data/intercensal/national/files/US- EST00INT-ALLDATA.csv. Accessed November 14, 2011
19. Lutkepohl H. New introduction to multiple time series analysis. Berlin: Birkhauser; 2006
20. Barnett AGDA. Analysing seasonal health data. Berlin: Springer; 2010
21. Newey WK, West K. A simple, positive semidefinite, heteroskedasticity and autocorrelation consistent covariance matrix. Econometrica. 1987;55(3):703-708
22. Chen YRG, Feng J, Ding M. Analyzing multiple nonlinear time series with extended Granger causality. Phys Lett A. 2004;324(1): 26-35
23. Hesse WME, Möller E, Arnold M, Schack B. The use of time-variant EEG Granger causality for inspecting directed interdependencies of neural assemblies. J Neurosci Methods. 2003;124(1):27-44
24. Granger CWJ. Causality, cointegration, and control. J Econ Dyn Control. 1988;12:551-559
25. Liebelt EL, DeAngelis CD. Evolving trends and treatment advances in pediatric poisoning. JAMA. 1999;282(12):1113-1115
26. Budnitz DS, Lovegrove MC. The last mile: Taking the final steps in preventing pediatric pharmaceutical poisonings. J Pediatr. 2012;160(2):190-192
27. Centers for Disease Control and Prevention. The PROTECT Initiative: Advancing Children's Medication Safety, 2012. Available at: Www.cdc.gov/ medicationsafety/protect/protect-initiative.html. Accessed June 30, 2012
28. RB Press release, September 25, 2012. Reckitt Benckiser Pharmaceuticals Inc. to Voluntarily Discontinue the Supply of Suboxone Tablets (buprenorphine and naloxone sublingual tablets [CIIII]. Available at www.rb.com/site/RKBR/ Templates/MediaInvestorsGeneral2. aspx?pageid=1328&cc=GB. Accessed January 16, 2013
29. Ogden CL, Carroll, MD, Kit BK, Flegal, KM. Prevalence of Obesity in the United States, 2009-2010 (NCHS Data Brief 82). U.S. Department of Health and Human Services, Centers for Disease Control and Prevention. www.cdc.gov/nchs/ data/databriefs/db82.pdf. Accessed August 1, 2012
30. Freedmam D.S. Centers for Disease Control and Prevention, Morbidity and Mortality Weekly Report. Obesity-United States, 1988-2008. Available at: Cdc.gov/mmwr/preview/mmwrhtml/su6001a15.htm?s-cid= su6001a15-w. Accessed August 1, 9, 2012
31. Centers for Disease Control and Prevention. Adult obesity facts. Available at: Www.cdc.gov/obesity/data/adult.html. Accessed July 12, 2012
32. Mintegi S, Fernández A, Alustiza J, et al. Emergency visits for childhood poisoning: A 2-year prospective multicenter survey in Spain. Pediatr Emerg Care. 2006;22(5):334-338
33. Centers for Disease Control and Prevention. CDC grand rounds: Prescription drug overdoses-a U.S. epidemic. MMWR Morb Mortal Wkly Rep. 2012;61(1):10-13
34. Tormoehlen LM, Mowry JB, Bodle JD, Rusyniak DE. Increased adolescent opioid use and complications reported to a poison control center following the 2000 JCAHO pain initiative. Clin Toxicol (Phila). 2011;49(6):492-498
35. US Food and Drug Administration. Lock It Up: Medicine Safety in Your Home. Available at: Www.fda.gov/ForConsuers/Consumer-Updates/ucm272905.htm. Accessed January 16, 2013
36. Centers for Disease Control and Prevention. Injury Prevention and Control. Policy Impact: Prescription Painkiller Overdoses. Available at: Www.cdc.gov/homeandrecreationalsafety/rxbrief. Accessed August 2, 2012
37. Volkow ND, McLellan TA. Curtailing diversion and abuse of opioid analgesics without jeopardizing pain treatment. JAMA. 2011;305(13):1346-1347