A Functional Promoter Polymorphism of IFITM3 Is Associated with Susceptibility to Pediatric Tuberculosis in Han Chinese Population

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Shen, Chen ^a   Wu, Xi rong ^a   Jiao, Wei wei ^a   Sun, Lin ^a   Feng, Wei xing ^a   Xiao, Jing ^a   Miao, Qing ^a   Liu, Fang ^a   Yin, Qing qin ^a   Zhang, Chen guang ^b   Guo, Ya jie ^a   Shen, A dong ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GUANOSINE; INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN; LUCIFERASE; MEMBRANE PROTEIN; MESSENGER RNA; UNCLASSIFIED DRUG;

ADULT; ALLELE; ARTICLE; CHILD; CHINESE; CHROMOSOME 11P; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; GENE; GENE LOCUS; GENETIC CODE; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; HAPLOTYPE; HUMAN; IFITM3 GENE; IMMUNE RESPONSE; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PROMOTER REGION; TUBERCULOSIS;

ADOLESCENT; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CHINA; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; INFANT; LYMPHOCYTES; MALE; MEMBRANE PROTEINS; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; RNA-BINDING PROTEINS; TRANSCRIPTIONAL ACTIVATION; TUBERCULOSIS;

EID: 84879947993     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067816     Document Type: Article

References (37)

1. Dye C, Williams BG, (2010) The population dynamics and control of tuberculosis. Science 328: 856-856.
2. Schurr E, (2007) Is susceptibility to tuberculosis acquired or inherited? J Intern Med 261(2): 106-11.
3. Bellamy R, (2003) Susceptibility to mycobacterial infections: the importance of host genetics. Genes Immun 4: 4-11.
4. Bellamy R, (2005) Genetic susceptibility to tuberculosis. Clin Chest Med 26: 233-246.
5. Möller M, Hoal EG, (2010) Current findings, challenges and novel approaches in human genetic susceptibility to tuberculosis. Tuberculosis (Edinb) 90: 71-83.
6. Yim JJ, Selvaraj P, (2010) Genetic susceptibility in tuberculosis. Respirology 15: 241-56.
7. Global tuberculosis report 2012. World Health Organization website. Available: http://www.who.int/tb/publications/global_report/en/index.html. Accessed 2013 May 30.
8. Jiang ZF, Yi ZW, Zhao SY (2006) Practical Pediatric Tuberculosis. Beijing: People's Medical Publishing House. pp. 431.
9. Newton SM, Brent AJ, Anderson S, Whittaker E, Kampmann B, (2008) Paediatric tuberculosis. Lancet Infect Dis 8: 498-510.
10. Rigouts L, (2009) Clinical practice: diagnosis of childhood tuberculosis. Eur J Pediatr 168: 1285-1290.
11. Alcais A, Fieschi C, Abel L, Casanova JL, (2005) Tuberculosis in children and adults: two distinct genetic diseases. J Exp Med 202: 1617-1621.
12. Walls T, Shingadia D, (2004) Global epidemiology of paediatric tuberculosis. J Infect 48: 13-22.
13. Seyfried NT, Huysentruyt LC, Atwood JA 3rd, Xia Q, Seyfried TN, et al. (2008) Up-regulation of NG2 proteoglycan and interferon-induced transmembrane proteins 1 and 3 in mouse astrocytoma: a membrane proteomics approach. Cancer Lett 263: 243-252.
14. Fan J, Peng Z, Zhou C, Qiu G, Tang H, et al. (2008) Gene-expression profiling in Chinese patients with colon cancer by coupling experimental and bioinformatic genomewide gene-expression analyses: identification and validation of IFITM3 as a biomarker of early colon carcinogenesis. Cancer 113: 266-275.
15. Hisamatsu T, Watanabe M, Ogata H, Ezaki T, Hozawa S, et al. (1999) Interferon-inducible gene family 1-8U expression in colitis-associated colon cancer and severely inflamed mucosa in ulcerative colitis. Cancer Res 59: 5927-5931.
16. Brass AL, Huang IC, Benita Y, John SP, Krishnan MN, et al. (2009) The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus. Cell 139: 1243-1254.
17. Jiang D, Weidner JM, Qing M, Pan XB, Guo H, et al. (2010) Identification of five interferon-induced cellular proteins that inhibit west nile virus and dengue virus infections. J Virol 84: 8332-8341.
18. Weidner JM, Jiang D, Pan XB, Chang J, Block TM, et al. (2010) Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms. J Virol 84: 12646-12657.
19. Feeley EM, Sims JS, John SP, Chin CR, Pertel T, et al. (2011) IFITM3 inhibits influenza A virus infection by preventing cytosolic entry. PLoS Pathog 7: e1002337.
20. Seo GS, Lee JK, Yu JI, Yun KJ, Chae SC, et al. (2010) Identification of the polymorphisms in IFITM3 gene and their association in a Korean population with ulcerative colitis. Exp Mol Med 42: 99-104.
21. Stark GR, Kerr IM, Williams BR, Silverman RH, Schreiber RD, (1998) How cells respond to interferons. Annu Rev Biochem 67: 227-264.
22. Lee J, Kornfeld H, (2010) Interferon-γ Regulates the Death of M. tuberculosis-Infected Macrophages. J Cell Death 3: 1-11.
23. Baldridge MT, King KY, Boles NC, Weksberg DC, Goodell MA, (2010) Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection. Nature 465: 793-797.
24. Vallinoto AC, Graça ES, Araújo MS, Azevedo VN, Cayres-Vallinoto I, et al. (2010) IFNG +874 T/A polymorphism and cytokine plasma levels are associated with susceptibility to Mycobacterium tuberculosis infection and clinical manifestation of tuberculosis. Hum. Immunol 71: 692-696.
25. He J, Wang J, Lei D, Ding S, (2010) Analysis of functional SNP in ifng/ifngr1 in Chinese Han population with tuberculosis. Scand J Immunol 71: 452-458.
26. Stein CM, Zalwango S, Malone LL, Won S, Mayanja-Kizza H, et al. (2008) Genome scan of M. tuberculosis infection and disease in Ugandans. PLoS One 3: e4094.
27. Liu H, Kang H, Liu R, Chen X, Zhao K, (2002) Maximal induction of a subset of interferon target genes requires the chromatin-remodeling activity of the BAF complex. Mol Cell Biol 22: 6471-6479.
28. Cuddapah S, Cui K, Zhao K, (2008) Transcriptional enhancer factor 1 (TEF-1/TEAD1) mediates activation of IFITM3 gene by BRGl. FEBS Lett 582: 391-397.
29. Li D, Peng Z, Tang H, Wei P, Kong X, et al. (2011) KLF4-mediated negative regulation of IFITM3 expression plays a critical role in colon cancer pathogenesis. Clin Cancer Res 17: 3558-3568.
30. Friedman RL, Manly SP, McMahon M, Kerr IM, Stark GR, (1984) Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells. Cell 38: 745-755.
31. Wu XR, Yin QQ, Jiao AX, Xu BP, Sun L, et al. (2012) Pediatric tuberculosis at Beijing Children's Hospital: 2002-2010. Pediatrics 130: e1433-1440.
32. The Respiratory Disease Group in Pediatrics Society of Chinese Medical Association (2006) The Editorial Board of Chinese Journal of Pediatrics, Diagnostic standards and therapeutic recommendations for pulmonary tuberculosis in children. Chin J Pediatr 44: 249-251.
33. Graham SM, Ahmed T, Amanullah F, Browning R, Cardenas V, et al. (2012) Evaluation of tuberculosis diagnostics in children: 1. Proposed clinical case definitions for classification of intrathoracic tuberculosis disease. Consensus from an expert panel. J Infect Dis 205Suppl 2: S199-208.
34. Li Z, Zhang Z, He Z, Tang W, Li T, et al. (2009) A partition-ligation-combination-subdivision EM algorithm for haplotype inference with multiallelic markers: update of the SHEsis (http://analysis.bio-x.cn). Cell Res. 19: 519-523.
35. QUANTO 1.1: A computer program for power and sample size calculations for genetic-epidemiology studies. Gene x Environment, Gene x Gene Interaction Home page website. Available: http://hydra.usc.edu/gxe. Accessed 2013 May 30.
36. Singh SB, Davis AS, Taylor GA, Deretic V, (2006) Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science 313: 1438-1441.
37. Li X, Yang Y, Zhou F, Zhang Y, Lu H, et al. (2011) SLC11A1 (NRAMP1) polymorphisms and tuberculosis susceptibility: updated systematic review and meta-analysis. PLoS One 6: e15831.