Studying morphine biosynthesis using transgenic opium poppy (Papaver somniferum L.)

Acta Horticulturae

Volumn 680, Issue , 2005, Pages 37-43

  Frick, S ^a   Kramell, R ^a   Kutchan, T M ^a   Larkin, P J ^b  

^a LEIBNIZ INSTITUTE OF PLANT BIOCHEMISTRY   (Germany)

^b CSIRO   (Australia)

Author keywords

Agrobacterium tumefaciens; Benzylisoquinoline alkaloids; Berberine bridge enzyme; Metabolic engineering; Somatic embryogenesis; Transformation

Indexed keywords

EID: 84879944110     PISSN: 05677572     EISSN: None     Source Type: Book Series    
DOI: 10.17660/ActaHortic.2005.680.4     Document Type: Conference Paper

References (13)

1. Belny, M., Hérouart, D., Thomasset, B., Havid, H., Jacquin-Dubreuil, A. and David, A. 1997. Transformation of Papaver somniferum cell suspensions cultures with saml from A. thaliana results in cell lines of different S-adenosyl-L-methionine synthase activity. Physiol. Plant. 99:233-240.
2. Facchini, P.J., Penzes, C, Johnson, A.G. and Bull, D. 1996. Molecular cloning and characterization of berberine bridge enzyme genes from opium poppy. Plant Physiol. 112:1669-1677.
3. Huang, F.C. and Kutchan, T.M. 2000. Distribution of morphinan and benzo[c]phenanthridine alkaloid gene transcript accumulation in Papaver somniferum. Phytochemistry 53:555-564.
4. Kamo, K., Kimoto, W., Hsu, A.F., Mahlberg, P.G. and Bills, D.D. 1982. Morphinane alkaloids in cultured tissues and redifferentiated organs of Papaver somniferum. Phytochemistry 21:219-222.
5. Kutchan, T.M. 1998. Molecular genetics of plant alkaloid biosynthesis. In: G. Cordell (ed.), The alkaloids 50:253-316, Academic Press, San Diego.
6. Larkin, P.J., Chitty, J.A. and Brettell, R.I.S. 1999. Methods for plant transformation and regeneration. International patent publication number WO 99/34663.
7. Nessler, C.L. 1982. Somatic embryogenesis in the opium poppy Papaver somniferum. Physiol. Plant. 55:453-458.
8. Nessler, C.L. and Mahlberg, P.G. 1979. Ultrastructure of laticifers in redifferentiated organs on callus from Papaver somniferum. Can. J. Bot. 57:675-685.
9. Park, S.U. and Facchini, P. 2000. Agrobacterium-mediated transformation of opium poppy, Papaver somniferum, via shoot organogenesis. J. Plant Physiol. 157:207-214.
10. Park, S.U., Yu, M. and Facchini, P.J. 2002. Antisense RNA-mediated suppression of benzophenanthridine alkaloid biosynthesis in transgenic cell cultures of California poppy. Plant Physiol. 128:696-706.
11. Schuchmann, R. and Wellmann, E. 1983. Somatic embryogenesis of tissue cultures of Papaver somniferum and Papaver orientale and its relationship to alkaloid and lipid metabolism. Plant Cell Rep. 2:88-91.
12. Staba, E.J., Zito, S. and Amin, M. 1982. Alkaloid production from Papaver tissue cultures. J. Nat. Prod. 45:256-262.
13. Yoshikawa, T. and Furuya, T. 1983. Regeneration and in vitro flowering of plants derived from callus cultures of opium poppy (Papaver somniferum). Experientia 39:1031-1033.