Can emerging drug classes improve R&D productivity?

Drug Discovery Today

Volumn 18, Issue 13-14, 2013, Pages 607-609

  Meier, Christoph ^a   Cairns Smith, Sarah ^a   Schulze, Ulrik ^a  

^a BOSTON CONSULTING GROUP   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PRODUCT; CYTOKINE RECEPTOR; CYTOTOXIN; LIFITEGRAST; MARAVIROC; MONOCLONAL ANTIBODY; RG 7112; SMALL MOLECULE TRANSPORT AGENT; TRASTUZUMAB EMTANSINE; UNCLASSIFIED DRUG;

ANTIBODY DRUG CONJUGATE; ANTISENSE THERAPY; BIOTECHNOLOGY; BREAST CANCER; CELL THERAPY; CYTOTOXICITY; DRUG CONJUGATION; DRUG DESIGN; DRUG EFFICACY; DRUG INDUSTRY; DRUG MANUFACTURE; DRUG POTENCY; DRUG STABILITY; EDITOR; EDITORIAL; GENE THERAPY; HUMAN; MOLECULE; PROTEIN PROTEIN INTERACTION; SMALL MOLECULE INHIBITOR OF PROTEIN PROTEIN INTERACTION;

ANIMALS; BIOMEDICAL RESEARCH; COST-BENEFIT ANALYSIS; DIFFUSION OF INNOVATION; DRUG DISCOVERY; DRUG INDUSTRY; EFFICIENCY; HUMANS; IMMUNOCONJUGATES; MOLECULAR TARGETED THERAPY; ORGANIZATIONAL OBJECTIVES; PHARMACOLOGY; PROTEIN BINDING;

EID: 84879940511     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2013.05.006     Document Type: Editorial

References (10)

1. J. Scannell The Long View: Pharma R&D Productivity - When the Cures Fail It Makes Sense to Check the Diagnosis. Bernstein Research 2010
2. P. Tollman Identifying R&D outliers Nat. Rev. Drug Discov. 10 2011 653 654
3. W.T. Clarke, and P.W. Marks Gemtuzumab ozogamicin: is there room for salvage? Blood 116 2010 2618 2619
4. Citeline database - excludes antibody-radioisotope conjugates and fusion protein toxins.
5. EvaluatePharma database. Consensus analyst forecast of drug sales for 2018.
6. S.M. Paul How to improve R&D productivity: the pharmaceutical industry's grand challenge Nat. Rev. Drug Discov. 9 2010 203 214
7. Celtic Therapeutics Launches $50M Antibody Drug Conjugates Development Company with 10 ADC Development Programs (Reuters - March 26, 2012).
8. A. Whitty, and G. Kumaravel Between a rock and a hard place? Nat. Chem. Biol. 2 2006 112 118
9. T.R. Gadek, and J.B. Nicholas Small molecule antagonists of proteins Biochem. Pharmacol. 65 2003 1 8
10. A. Mullard Protein-protein interaction inhibitors get into the groove Nat. Rev. Drug Discov. 11 2012 173 175