Current cholesterol guidelines and clinical reality: A comparison of two cohorts of coronary artery disease patients

Swiss Medical Weekly

Volumn 143, Issue , 2013, Pages

  Vonbank, Alexander ^a,b,c   Saely, Christoph H ^a,b,c   Rein, Philipp ^a,b,c   Sturn, Daniel ^b,c   Drexel, Heinz ^a,b,c,d,e  

^a Vorarlberg Institute for Vascular Investigation and Treatment ^*  (Austria)

^b Academic Teaching Hospital   (Austria)

^c PRIVATE UNIVERSITY OF THE PRINCIPALITY OF LIECHTENSTEIN   (Liechtenstein)

^d DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^e not available   (Austria)

Author keywords

Coronary artery disease; Guidelines; High risk patients; Hyperlipidemia; Lipid goals; Lipid management; Type 2 diabetes

Indexed keywords

CHOLESTEROL; HEMOGLOBIN A1C; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ADULT; ANGIOCARDIOGRAPHY; ARTICLE; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DIASTOLIC BLOOD PRESSURE; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; PRACTICE GUIDELINE; SMOKING CESSATION; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; AGED; BLOOD; COHORT ANALYSIS; COMORBIDITY; COMPLICATION; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; RETROSPECTIVE STUDY; RISK; RISK FACTOR; SEX DIFFERENCE; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA; STATISTICS;

AGED; CHOLESTEROL, LDL; COHORT STUDIES; COMORBIDITY; CORONARY ARTERY DISEASE; DIABETES MELLITUS, TYPE 2; FEMALE; GUIDELINE ADHERENCE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LOGISTIC MODELS; MALE; MIDDLE AGED; ODDS RATIO; PRACTICE GUIDELINES AS TOPIC; RETROSPECTIVE STUDIES; RISK FACTORS; SEX FACTORS;

EID: 84879930639     PISSN: 14247860     EISSN: 14243997     Source Type: Journal    
DOI: 10.4414/smw.2013.13828     Document Type: Article

References (25)

1. Kannel WB. Lipids, diabetes, and coronary heart disease: insights from the Framingham Study. Am Heart J. 1985;110:1100-07. (Pubitemid 16052615)
2. Stone NJ, Bilek S, Rosenbaum S. Recent National Cholesterol Education Program Adult Treatment Panel III update: adjustments and options. Am J Cardiol. 2005;96:53E-9E. (Pubitemid 41140371)
3. Graham I, Atar D, Borch-Johnsen K, Boysen G, Burell G, Cifkova R. European guidelines on cardiovascular disease prevention in clinical practice: full text. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of nine societies and by invited experts). Eur J Cardiovasc Prev Rehabil. 2007;14(Suppl 2):S1-113.
4. Jeger R, Dieterle T. Statins: have we found the Holy Grail? Swiss Med Wkly. 2012;142:w13515.
5. Braunersreuther V, Mach F, Montecucco F. Statins and stent thrombosis. Swiss Med Wkly. 2012;142:w13525.
6. Baigent C, Blackwell L, Emberson J, Holland LE, Reith C, Bhala N. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet. 2010;376:1670-81.
7. Baigent C, Keech A, Kearney PM, Blackwell L, Buck G, Pollicino C. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet. 2005;366:1267-78.
8. Mihaylova B, Emberson J, Blackwell L, Keech A, Simes J, Barnes EH. The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials. Lancet. 2012;380:581-90.
9. Kearney PM, Blackwell L, Collins R, Keech A, Simes J, Peto R. Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis. Lancet. 2008;371:117-25.
10. Reiner Z, Catapano AL, De Backer G, Graham I, Taskinen MR, Wiklund O. ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Eur Heart J. 2011;32:1769-818.
11. AAS Guidelines. 2013; http://www.aas.at.
12. AGLA guidelines. 2013; http://www.agla.ch.
13. Vonbank A, Saely CH, Rein P, Beer S, Breuss J, Boehnel C. Insulin resistance is associated with the metabolic syndrome and is not directly linked to coronary artery disease. Clin Chim Acta. 2011;412:1003-7.
14. Saely CH, Rein P, Vonbank A, Huber K, Drexel H. Type 2 diabetes and the progression of visualized atherosclerosis to clinical cardiovascular events. Int J Cardiol. 2012.
15. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA. 2003;289:2560-72. (Pubitemid 37430158)
16. Zimmet P, Alberti G, de Court. New classification and criteria for diabetes: moving the goalposts closer. Med J Aust. 1998;168:593-4. (Pubitemid 28288615)
17. Drexel H, Amann FW, Rentsch K, Neuenschwander C, Luethy A, Khan SI. Relation of the level of high-density lipoprotein subfractions to the presence and extent of coronary artery disease. Am J Cardiol. 1992;70:436-40.
18. Drexel H, Amann FW, Beran J, Rentsch K, Candinas R, Muntwyler J. Plasma triglycerides and three lipoprotein cholesterol fractions are independent predictors of the extent of coronary atherosclerosis. Circulation. 1994;90:2230-5. (Pubitemid 24354306)
19. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation. 2002;106:3143-421.
20. Qayyum R, Chattha AA, Bhullar N, Katsetos M, Schulman P. Achievement of national cholesterol education program goals by patients with dyslipidemia in rural ambulatory care settings. Prev Cardiol. 2006;9:192-7.
21. Coon P, Zulkowski K. Adherence to American Diabetes Association standards of care by rural health care providers. Diabetes Care. 2002;25:2224-9. (Pubitemid 41071032)
22. Karalis DG, Subramanya RD, Hessen SE, Liu L, Victor MF. Achieving Optimal Lipid Goals in Patients With Coronary Artery Disease. Am J Cardiol. 2011.
23. Roden M, Huber K. Lipid profiles and therapy status in the secondary prevention of high risk patients with cardiovascular disease and/or diabetes mellitus: the Austrian Hospital Screening Project (HSP). Wien Klin Wochenschr. 2008;120:558-65.
24. Kitkungvan D, Lynn Fillipon NM, Dani SS, Downey BC. Low-density lipoprotein cholesterol target achievement in patients at high risk for coronary heart disease. J Clin Lipidol. 2010;4:293-7.
25. Martin SS, Gosch K, Kulkarni KR, Spertus JA, Mathews R, Ho PM. Modifiable factors associated with failure to attain low-density lipoprotein cholesterol goal at 6 months after acute myocardial infarction. Am Heart J. 2013;165:26-33.