Treadmill exercise elevates striatal dopamine D2 receptor binding potential in patients with early Parkinson's disease

NeuroReport

Volumn 24, Issue 10, 2013, Pages 509-514

  Fisher, Beth E ^a,c   Li, Quanzheng ^b   Nacca, Angelo ^c   Salem, George J ^a,c   Song, Jooeun ^a   Yip, Jeanine ^a   Hui, Jennifer S ^c   Jakowec, Michael W ^a,c   Petzinger, Giselle M ^a,c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b NONE   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

basal ganglia; experience dependent plasticity; fallypride; motor behavior; neuroplasticity; PET imaging; rehabilitation; running

Indexed keywords

DOPAMINE 2 RECEPTOR; FLUORINE 18;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEASIBILITY STUDY; FEMALE; HUMAN; MALE; MOTOR PERFORMANCE; NERVE CELL PLASTICITY; NEUROTRANSMISSION; PARKINSON DISEASE; PILOT STUDY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TASK PERFORMANCE; TREADMILL EXERCISE; UNIFIED PARKINSON DISEASE RATING SCALE;

BENZAMIDES; BIOMECHANICAL PHENOMENA; BRAIN; EXERCISE THERAPY; FEMALE; GAIT; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEOSTRIATUM; NEURONAL PLASTICITY; PARKINSON DISEASE; PILOT PROJECTS; POSITRON-EMISSION TOMOGRAPHY; POSTURE; PSYCHOMOTOR PERFORMANCE; PYRROLIDINES; RADIOPHARMACEUTICALS; RECEPTORS, DOPAMINE D2;

EID: 84879929197     PISSN: 09594965     EISSN: 1473558X     Source Type: Journal    
DOI: 10.1097/WNR.0b013e328361dc13     Document Type: Article

References (28)

1. Fisher BE, Wu AD, Salem GJ, Song J, Lin CH, Yip J, et al. The effect of exercise training in improving motor performance and corticomotor excitability in people with early Parkinson's disease. Arch Phys Med Rehabil 2008; 89:1221-1229.
2. Alberts JL, Linder SM, Penko AL, Lowe MJ, Phillips M. It is not about the bike, it is about the pedaling: forced exercise and Parkinson's disease. Exerc Sport Sci Rev 2011; 39:177-186.
3. Ellis T, Cavanaugh JT, Earhart GM, Ford MP, Foreman KB, Fredman L, et al. Factors associated with exercise behavior in people with Parkinson disease. Phys Ther 2011; 91:1838-1848.
4. Chen H, Zhang SM, Schwarzschild MA, Hernan MA, Ascherio A. Physical activity and the risk of Parkinson disease. Neurology 2005; 64:664-669.
5. Xu Q, Park Y, Huang X, Hollenbeck A, Blair A, Schatzkin A, et al. Physical activities and future risk of Parkinson disease. Neurology 2010; 75:341-348.
6. Petzinger GM, Walsh JP, Akopian G, Hogg E, Abernathy A, Arevalo P, et al. Effects of treadmill exercise on dopaminergic transmission in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-lesioned mouse model of basal ganglia injury. J Neurosci 2007; 27:5291-5300.
7. Gerfen CR, Surmeier DJ. Modulation of striatal projection systems by dopamine. Annu Rev Neurosci 2011; 34:441-466.
8. Picconi B, Piccoli G, Calabresi P. Synaptic dysfunction in Parkinson's disease. Adv Exp Med Biol 2012; 970:553-572.
9. Calabresi P, Picconi B, Tozzi A, Di Filippo M. Dopamine-mediated regulation of corticostriatal synaptic plasticity. Trends Neurosci 2007; 30:211-219.
10. Vuckovic MG, Li Q, Fisher B, Nacca A, Leahy RM, Walsh JP, et al. Exercise elevates dopamine D2 receptor in a mouse model of Parkinson's disease: in vivo imaging with [(1)F]fallypride. Mov Disord 2010; 25:2777-2784.
11. Song J, Sigward S, Fisher B, Salem GJ. Altered dynamic postural control during step turning in persons with early-stage Parkinson's disease. Parkinsons Dis 2012; 2012:386962.
12. Goetz CG, Fahn S, Martinez-Martin P, Poewe W, Sampaio C, Stebbins GT, et al. Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Process, format, and clinimetric testing plan. Mov Disord 2007; 22:41-47.
13. 18F-fallypride. Nucl Med Biol 1999; 26:519-527.
14. Kessler RM, Ansari MS, Riccardi P, Li R, Jayathilake K, Dawant B, et al. Occupancy of striatal and extrastriatal dopamine D2 receptors by clozapine and quetiapine. Neuropsychopharmacology 2005; 31: 1991-2001.
15. Fisher BE, Petzinger GM, Nixon K, Hogg E, Bremmer S, Meshul CK, et al. Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-lesioned mouse basal ganglia. J Neurosci Res 2004; 77:378-390.
16. VanLeeuwen JE, Petzinger GM, Walsh JP, Akopian GK, Vuckovic M, Jakowec MW. Altered AMPA receptor expression with treadmill exercise in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-lesioned mouse model of basal ganglia injury. J Neurosci Res 2010; 88:650-668.
17. Logan J, Fowler JS, Volkow ND, Wang GJ, Ding YS, Alexoff DL. Distribution volume ratios without blood sampling from graphical analysis of PET data. J Cereb Blood Flow Metab 1996; 16:834-840.
18. 18F-fallypride in extrastriatal brain regions in nonhuman primates using PET. Brain Res 2005; 1032:77-84.
19. Cropley VL, Innis RB, Nathan PJ, Brown AK, Sangare JL, Lerner A, et al. Small effect of dopamine release and no effect of dopamine depletion on [(18)F]fallypride binding in healthy humans. Synapse 2008; 62: 399-408.
20. Bezard E, Dovero S, Prunier C, Ravenscroft P, Chalon S, Guilloteau D, et al. Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-lesioned macaque model of Parkinson's disease. J Neurosci 2001; 21:6853-6861.
21. Rinne JO, Laihinen A, Ruottinen H, Ruotsalainen U, Nagren K, Lehikoinen P, et al. Increased density of dopamine D2 receptors in the putamen, but not in the caudate nucleus in early Parkinson's disease: a PET study with [11C]raclopride. J Neurol Sci 1995; 132:156-161.
22. Slifstein M, Kegeles LS, Xu X, Thompson JL, Urban N, Castrillon J, et al. Striatal and extrastriatal dopamine release measured with PET and [(18)F] fallypride. Synapse 2010; 64:350-362.
23. Goerendt IK, Messa C, Lawrence AD, Grasby PM, Piccini P, Brooks DJ. Dopamine release during sequential finger movements in health and Parkinson's disease: a PET study. Brain 2003; 126:312-325.
24. Pisani A, Centonze D, Bernardi G, Calabresi P. Striatal synaptic plasticity: implications for motor learning and Parkinson's disease. Mov Disord 2005; 20:395-402.
25. Calabresi P, Pisani A, Mercuri NB, Bernardi G. The corticostriatal projection: from synaptic plasticity to dysfunctions of the basal ganglia. Trends Neurosci 1996; 19:19-24.
26. O'Dell SJ, Gross NB, Fricks AN, Casiano BD, Nguyen TB, Marshall JF. Running wheel exercise enhances recovery from nigrostriatal dopamine injury without inducing neuroprotection. Neuroscience 2007; 144: 1141-1151.
27. Bostan AC, Strick PL. The cerebellum and basal ganglia are interconnected. Neuropsychol Rev 2010; 20:261-270.
28. Yang J, Sadler TR, Givrad TK, Maarek JM, Holschneider DP. Changes in brain functional activation during resting and locomotor states after unilateral nigrostriatal damage in rats. Neuroimage 2007; 36:755-773.