The anti-obesity effect of natural vanadium-containing jeju ground water

Biological Trace Element Research

Volumn 151, Issue 2, 2013, Pages 294-300

  Park, Seon Joo ^a   Youn, Cha Kyung ^a   Hyun, Jin Won ^b   You, Ho Jin ^a  

^a Chosun University   (South Korea)

^b Jeju National University School of Medicine   (South Korea)

Author keywords

Adipogenesis; Jeju ground water; Obesity; Preadipocyte differentiation

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; CHOLESTEROL; DEXAMETHASONE; FATTY ACID; GLUCOSE; GROUND WATER; INSULIN; ISOBUTYLMETHYLXANTHINE; JEJU GROUND WATER; LEPTIN; LIPOPROTEIN LIPASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VANADIUM; ANTIOBESITY AGENT; AZO COMPOUND; MESSENGER RNA; OIL RED O;

ADIPOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CCAAT ENHANCER BINDING PROTEIN ALPHA GENE; CELL DIFFERENTIATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE FUNCTION; GLUCOSE BLOOD LEVEL; LIPID STORAGE; MALE; MOUSE; NONHUMAN; OBESITY; PEROXISOME ACTIVATED RECEPTOR GAMMA GENE; PROADIPOCYTE; THERAPY EFFECT; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN; ADIPOCYTE; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL STRAIN 3T3; CHEMISTRY; CULTURE MEDIUM; CYTOLOGY; DRUG EFFECT; FIBROBLAST; GENETIC TRANSCRIPTION; GENETICS; LIPID DIET; LIPID METABOLISM; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; SOUTH KOREA; WESTERN BLOTTING;

ANIMALIA; MUS;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; ANTI-OBESITY AGENTS; AZO COMPOUNDS; BLOTTING, WESTERN; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL DIFFERENTIATION; CELLS, CULTURED; CULTURE MEDIA; DEXAMETHASONE; DIET, HIGH-FAT; FIBROBLASTS; GROUNDWATER; INSULIN; LIPID METABOLISM; LIPOPROTEIN LIPASE; MALE; MICE; MICE, INBRED C57BL; OBESITY; PPAR GAMMA; REAL-TIME POLYMERASE CHAIN REACTION; REPUBLIC OF KOREA; RNA, MESSENGER; TRANSCRIPTION, GENETIC; VANADIUM;

MLCS; MLOWN;

EID: 84879925289     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-012-9557-8     Document Type: Article

References (25)

1. Haslam DW, James WP (2005) Obesity. Lancet 36:1197-1209
2. Trayhurn P (2005) Endocrine and signalling role of adipose tissue: new perspectives on fat. Acta Physiol Scand 184:285-293
3. Fernyhough ME, Bucci LR, Hausman GJ, Antonio J, Vierck JL, Dodson MV (2005) Gaining a solid grip on adipogenesis. Tissue Cell 37:335-338
4. Gregoire FM (2001) Adipocyte differentiation: from fibroblast to endocrine cell. Exp Biol Med 226:997-1002
5. Koutnikova H, Auwerx J (2001) Regulation of adipocyte differentiation. Ann Med 33:556-561
6. Wu Z, Rosen ED, Brun R, Hauser S, Adelmant G, Troy AE, McKeon C, Darlington GJ, Spiegelman BM (1999) Cross-regulation of C/EBPα and PPARγ controls the transcriptional pathway of adipogenesis and insulin sensitivity. Mol Cell 3:151-158
7. MacDougald OA, Lane MD (1995) Transcriptional regulation of gene expression during adipocyte differentiation. Annu Rev Biochem 64:345-373
8. Rosen ED, Walkey CJ, Puigserver P, Spiegelman BM (2000) Transcriptional regulation of adipogenesis. Genes Dev 14:1293-1307
9. Kato K, Yamada S, Ohmori Y, Oki T, Kawamoto E, Shirama K, Watanabe Y (2004) Natural vanadium-containing Mt. Fuji ground water improves hypo-activity of liver insulin receptor in Goto-Kakisaki rats. Mol Cell Biochem 267:203-207
10. Hwang SL, Chang HW (2012) Natural vanadium containing Jeju ground water stimulates glucose uptake through the activation of AMP-activated protein kinase L6 myotubes. Mol Cell Biochem 360:401-409
11. Kim AD, Zhang R, Kang KA, You HJ, Kang KG, Hyun JW (2012) Jeju ground water containing vanadium enhances antioxidant systems in human liver cells. Biol Trace Elem Res 147:16-24
12. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25:402-408
13. Wu Z, Xie Y, Morrison RF, Bucher NL, Farmer SR (1998) PPARγ induces the insulin-dependent glucose transporter GLUT4 in the absence of C/EBPα during the conversion of 3 T3 fibroblasts into adipocytes. J Clin Invest 101:22-32
14. Fu Y, Luo N, Klein RL, Garvey WT (2005) Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation. Lipid Res 46:1369-1379
15. Sayama K, Lin S, Zheng G, Oguni I (2000) Effects of green tea on growth, food utilization and lipid metabolism in mice. In Vivo 14:481-484
16. Mochizuki M, Hasegawa N (2004) Effects of green tea catechin-induced lipolysis on cytosol glycerol content in differentiated 3 T3-L1 cells. Phytother Res 18:945-946
17. Kim JK, So H, Youn MJ, Kim HJ, Kim Y, Park C, Kim SJ, Ha YA, Chai KY, Kim SM, Kim KY, Park R (2007) Hibiscus sabdariffa L. water extract inhibits the adipocyte differentiation through the PI3-K and MAPK pathway. J Ethnopharmacol 114:260-267
18. Hwang HS, Kim SH, Yoo YG, Chu YS, Shon YH, Nam KS, Yun JW (2009) Inhibitory effect of deep-sea water on differentiation of 3 T3-L1 adipocytes. Mar Biotechnol (NY) 11:161-168
19. Evangelou AM (2002) Vanadium in cancer treatment. Crit Rev Oncol Hematol 42:249-265
20. Seale AP, de Jesus LA, Park MC, Kim YS (2006) Vanadium and insulin increase adiponectin production in 3 T3-L1 adipocytes. Pharmacol Res 54:30-38
21. Shukla R, Bhonde RR (2008) Adipogenic action of vanadium: a new dimension in treating diabetes. Biometals 21:205-210
22. Kim AD, Kang KA, Zhang R, Lim CM, Jee Y, Lee NH, You HJ, Ko KS, Hyun JW (2010) Reactive oxygen species scavenging effects of Jeju waters containing vanadium components. Cancer Prev Res 15:111-117
23. Tontonoz P, Graves RA, Budavari AI, Erdjument-Bromage H, Lui M, Hu E, Tempst P, Spiegelman BM (1994) Adipocyte-specific transcription factor ARF6 is a hetero-dimeric complex of two nuclear hormone receptors, PPAR gamma and RXR alpha. Nucleic Acids Res 22:5628-5634
24. Tontonoz P, Hu E, Graves RA, Budavari AI, Spiegelman BM (1994) mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev 8:1224-1234
25. Surwit RS, Kuhn CM, Cochrane C, McCubbin JA, Feinglos MN (1988) Diet-induced type II diabetes in C57BL/6 J mice. Diabetes 37:1163-1167