메뉴 건너뛰기




Volumn 20, Issue 7, 2013, Pages 785-794

Oral salmon calcitonin protects against impaired fasting glycemia, glucose intolerance, and obesity induced by high-fat diet and ovariectomy in rats

Author keywords

Insulin resistance; Menopause; Obesity; Ovariectomy; Salmon calcitonin

Indexed keywords

GLUCOSE; INSULIN; SALCATONIN;

EID: 84879924058     PISSN: 10723714     EISSN: 15300374     Source Type: Journal    
DOI: 10.1097/gme.0b013e31827c58ab     Document Type: Article
Times cited : (17)

References (54)
  • 1
    • 0038645816 scopus 로고    scopus 로고
    • The emergence of the metabolic syndrome with menopause
    • Carr MC. The emergence of the metabolic syndrome with menopause. J Clin Endocrinol Metab 2003;88:2404-2411.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2404-2411
    • Carr, M.C.1
  • 2
    • 77956257843 scopus 로고    scopus 로고
    • Central effects of estradiol in the regulation of food intake, body weight, and adiposity
    • Brown LM, Clegg DJ. Central effects of estradiol in the regulation of food intake, body weight, and adiposity. J Steroid Biochem Mol Biol 2010;122:65-73.
    • (2010) J Steroid Biochem Mol Biol , vol.122 , pp. 65-73
    • Brown, L.M.1    Clegg, D.J.2
  • 3
    • 45649083873 scopus 로고    scopus 로고
    • Metabolic syndrome after menopause and the role of hormones
    • Lobo RA. Metabolic syndrome after menopause and the role of hormones. Maturitas 2008;60:10-18.
    • (2008) Maturitas , vol.60 , pp. 10-18
    • Lobo, R.A.1
  • 4
    • 47249135502 scopus 로고    scopus 로고
    • Metabolic syndrome and the menopause
    • Kaaja RJ. Metabolic syndrome and the menopause. Menopause Int 2008; 14:21-25.
    • (2008) Menopause Int , vol.14 , pp. 21-25
    • Kaaja, R.J.1
  • 5
    • 3142550827 scopus 로고    scopus 로고
    • Antidiabetic actions of estrogen: Insight from human and genetic mouse models
    • Louet JF, LeMay C, Mauvais-Jarvis F. Antidiabetic actions of estrogen: insight from human and genetic mouse models. Curr Atheroscler Rep 2004;6:180-185.
    • (2004) Curr Atheroscler Rep , vol.6 , pp. 180-185
    • Louet, J.F.1    Lemay, C.2    Mauvais-Jarvis, F.3
  • 6
    • 34047237367 scopus 로고    scopus 로고
    • Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause
    • Rossouw JE, Prentice RL, Manson JE, et al. Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA 2007;297:1465-1477.
    • (2007) JAMA , vol.297 , pp. 1465-1477
    • Rossouw, J.E.1    Prentice, R.L.2    Manson, J.E.3
  • 7
    • 33748119290 scopus 로고    scopus 로고
    • Prior hormone therapy and breast cancer risk in the Women's health initiative randomized trial of estrogen plus progestin
    • Anderson GL, Chlebowski RT, Rossouw JE, et al. Prior hormone therapy and breast cancer risk in the Women's Health Initiative randomized trial of estrogen plus progestin. Maturitas 2006;55:103-115.
    • (2006) Maturitas , vol.55 , pp. 103-115
    • Anderson, G.L.1    Chlebowski, R.T.2    Rossouw, J.E.3
  • 8
    • 68949177102 scopus 로고    scopus 로고
    • Gut hormones: Implications for the treatment of obesity
    • Neary MT, Batterham RL. Gut hormones: implications for the treatment of obesity. Pharmacol Ther 2009;124:44-56.
    • (2009) Pharmacol Ther , vol.124 , pp. 44-56
    • Neary, M.T.1    Batterham, R.L.2
  • 9
    • 53549085157 scopus 로고    scopus 로고
    • New drugs for type 2 diabetes mellitus: What is their place in therapy?
    • Krentz AJ, Patel MB, Bailey CJ. New drugs for type 2 diabetes mellitus: what is their place in therapy? Drugs 2008;68:2131-2162.
    • (2008) Drugs , vol.68 , pp. 2131-2162
    • Krentz, A.J.1    Patel, M.B.2    Bailey, C.J.3
  • 10
    • 0036751254 scopus 로고    scopus 로고
    • The human amylin analog, pramlintide, reduces postprandial hyperglucagonemia in patients with type 2 diabetes mellitus
    • Fineman M, Weyer C, Maggs DG, Strobel S, Kolterman OG. The human amylin analog, pramlintide, reduces postprandial hyperglucagonemia in patients with type 2 diabetes mellitus. Horm Metab Res 2002; 34:504-508.
    • (2002) Horm Metab Res , vol.34 , pp. 504-508
    • Fineman, M.1    Weyer, C.2    Maggs, D.G.3    Strobel, S.4    Kolterman, O.G.5
  • 11
    • 0345328762 scopus 로고    scopus 로고
    • Addition of pramlintide to insulin therapy lowers HbA1c in conjunction with weight loss in patients with type 2 diabetes approaching glycaemic targets
    • Hollander P, Ratner R, Fineman M, et al. Addition of pramlintide to insulin therapy lowers HbA1c in conjunction with weight loss in patients with type 2 diabetes approaching glycaemic targets. Diabetes Obes Metab 2003;5:408-414.
    • (2003) Diabetes Obes Metab , vol.5 , pp. 408-414
    • Hollander, P.1    Ratner, R.2    Fineman, M.3
  • 12
    • 1042280287 scopus 로고    scopus 로고
    • Pramlintide reduces postprandial glucose excursions when added to insulin lispro in subjects with type 2 diabetes: A dose-timing study
    • Maggs DG, Fineman M, Kornstein J, et al. Pramlintide reduces postprandial glucose excursions when added to insulin lispro in subjects with type 2 diabetes: a dose-timing study. Diabetes Metab Res Rev 2004; 20:55-60.
    • (2004) Diabetes Metab Res Rev , vol.20 , pp. 55-60
    • Maggs, D.G.1    Fineman, M.2    Kornstein, J.3
  • 13
    • 64949171578 scopus 로고    scopus 로고
    • Control of food intake and energy expenditure by amylintherapeutic implications
    • Lutz TA. Control of food intake and energy expenditure by amylintherapeutic implications. Int J Obes (Lond) 2009;33(suppl 1):S24-S27.
    • (2009) Int J Obes (Lond) , vol.33 , Issue.SUPPL. 1
    • Lutz, T.A.1
  • 14
    • 77953914540 scopus 로고    scopus 로고
    • Central amylin acts as an adiposity signal to control body weight and energy expenditure
    • Wielinga PY, Lowenstein C, Muff S, Munz M, Woods SC, Lutz TA. Central amylin acts as an adiposity signal to control body weight and energy expenditure. Physiol Behav 2010;101:45-52.
    • (2010) Physiol Behav , vol.101 , pp. 45-52
    • Wielinga, P.Y.1    Lowenstein, C.2    Muff, S.3    Munz, M.4    Woods, S.C.5    Lutz, T.A.6
  • 15
    • 69749086148 scopus 로고    scopus 로고
    • Enhanced weight loss with pramlintide/metreleptin: An integrated neurohormonal approach to obesity pharmacotherapy
    • Ravussin E, Smith SR, Mitchell JA, et al. Enhanced weight loss with pramlintide/metreleptin: an integrated neurohormonal approach to obesity pharmacotherapy. Obesity (Silver Spring) 2009;17:1736-1743.
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 1736-1743
    • Ravussin, E.1    Smith, S.R.2    Mitchell, J.A.3
  • 16
    • 34547621757 scopus 로고    scopus 로고
    • Pramlintide treatment reduces 24-h caloric intake and meal sizes and improves control of eating in obese subjects: A 6-wk translational research study
    • Smith SR, Blundell JE, Burns C, et al. Pramlintide treatment reduces 24-h caloric intake and meal sizes and improves control of eating in obese subjects: a 6-wk translational research study. Am J Physiol Endocrinol Metab 2007;293:E620-E627.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Smith, S.R.1    Blundell, J.E.2    Burns, C.3
  • 17
    • 56149124659 scopus 로고    scopus 로고
    • Sustained weight loss following 12-month pramlintide treatment as an adjunct to lifestyle intervention in obesity
    • Smith SR, Aronne LJ, Burns CM, Kesty NC, Halseth AE, Weyer C. Sustained weight loss following 12-month pramlintide treatment as an adjunct to lifestyle intervention in obesity. Diabetes Care 2008; 31:1816-1823.
    • (2008) Diabetes Care , vol.31 , pp. 1816-1823
    • Smith, S.R.1    Aronne, L.J.2    Burns, C.M.3    Kesty, N.C.4    Halseth, A.E.5    Weyer, C.6
  • 18
    • 78649846963 scopus 로고    scopus 로고
    • Enhanced amylin-mediated body weight loss in estradiol-deficient diet-induced obese rats
    • Trevaskis JL, Turek VF, Wittmer C, et al. Enhanced amylin-mediated body weight loss in estradiol-deficient diet-induced obese rats. Endocrinology 2010;151:5657-5668.
    • (2010) Endocrinology , vol.151 , pp. 5657-5668
    • Trevaskis, J.L.1    Turek, V.F.2    Wittmer, C.3
  • 19
    • 33751509016 scopus 로고    scopus 로고
    • Antiobesity effects of the A-cell hormone amylin in diet-induced obese rats: Effects on food intake, body weight, composition, energy expenditure, and gene expression
    • Roth JD, Hughes H, Kendall E, Baron AD, Anderson CM. Antiobesity effects of the A-cell hormone amylin in diet-induced obese rats: effects on food intake, body weight, composition, energy expenditure, and gene expression. Endocrinology 2006;147:5855-5864.
    • (2006) Endocrinology , vol.147 , pp. 5855-5864
    • Roth, J.D.1    Hughes, H.2    Kendall, E.3    Baron, A.D.4    Anderson, C.M.5
  • 20
    • 80052542660 scopus 로고    scopus 로고
    • A novel oral form of salmon calcitonin improves glucose homeostasis and reduces body weight in diet-induced obese rats
    • Feigh M, Henriksen K, Andreassen KV, et al. A novel oral form of salmon calcitonin improves glucose homeostasis and reduces body weight in diet-induced obese rats. Diabetes Obes Metab 2011;13:911-920.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 911-920
    • Feigh, M.1    Henriksen, K.2    Andreassen, K.V.3
  • 21
    • 0034025745 scopus 로고    scopus 로고
    • Amylin receptors mediate the anorectic action of salmon calcitonin (sCT)
    • Lutz TA, Tschudy S, Rushing PA, Scharrer E. Amylin receptors mediate the anorectic action of salmon calcitonin (sCT). Peptides 2000; 21:233-238.
    • (2000) Peptides , vol.21 , pp. 233-238
    • Lutz, T.A.1    Tschudy, S.2    Rushing, P.A.3    Scharrer, E.4
  • 23
    • 0036534622 scopus 로고    scopus 로고
    • Effects of amylin and salmon calcitonin on feeding and drinking behavior in pygmy goats
    • Del PE, Schade B, Riediger T, Lutz TA, Scharrer E. Effects of amylin and salmon calcitonin on feeding and drinking behavior in pygmy goats. Physiol Behav 2002;75:593-599.
    • (2002) Physiol Behav , vol.75 , pp. 593-599
    • Del, P.E.1    Schade, B.2    Riediger, T.3    Lutz, T.A.4    Scharrer, E.5
  • 24
    • 36048955667 scopus 로고    scopus 로고
    • Effects of intermittent intraperitoneal infusion of salmon calcitonin on food intake and adiposity in obese rats
    • Chelikani PK, Haver AC, Reidelberger RD. Effects of intermittent intraperitoneal infusion of salmon calcitonin on food intake and adiposity in obese rats. Am J Physiol Regul Integr Comp Physiol 2007;293: R1798-R1808.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293
    • Chelikani, P.K.1    Haver, A.C.2    Reidelberger, R.D.3
  • 25
    • 0037098736 scopus 로고    scopus 로고
    • Salmon calcitoninVa potent inhibitor of food intake in states of impaired leptin signalling in laboratory rodents
    • Eiden S, Daniel C, Steinbrueck A, Schmidt I, Simon E. Salmon calcitoninVa potent inhibitor of food intake in states of impaired leptin signalling in laboratory rodents. J Physiol 2002;541(pt 3):1041-1048.
    • (2002) J Physiol , vol.541 , Issue.PART 3 , pp. 1041-1048
    • Eiden, S.1    Daniel, C.2    Steinbrueck, A.3    Schmidt, I.4    Simon, E.5
  • 26
    • 34248647047 scopus 로고    scopus 로고
    • The acute effect of amylin and salmon calcitonin on energy expenditure
    • Wielinga PY, Alder B, Lutz TA. The acute effect of amylin and salmon calcitonin on energy expenditure. Physiol Behav 2007;91:212-217.
    • (2007) Physiol Behav , vol.91 , pp. 212-217
    • Wielinga, P.Y.1    Alder, B.2    Lutz, T.A.3
  • 27
    • 0021795308 scopus 로고
    • Synthetic salmon calcitonin is not diabetogenic in patients with normal or impaired glucose metabolism
    • Giustina G, Cerudelli B, Cimino A, Rigosa C, Rotondi A, Radaeli E. Synthetic salmon calcitonin is not diabetogenic in patients with normal or impaired glucose metabolism. J Endocrinol Invest 1985;8:19-23.
    • (1985) J Endocrinol Invest , vol.8 , pp. 19-23
    • Giustina, G.1    Cerudelli, B.2    Cimino, A.3    Rigosa, C.4    Rotondi, A.5    Radaeli, E.6
  • 28
    • 72749107757 scopus 로고    scopus 로고
    • Oral insulin: The rationale for this approach and current developments
    • Arbit E, Kidron M. Oral insulin: the rationale for this approach and current developments. J Diabetes Sci Technol 2009;3:562-567.
    • (2009) J Diabetes Sci Technol , vol.3 , pp. 562-567
    • Arbit, E.1    Kidron, M.2
  • 29
    • 79951615188 scopus 로고    scopus 로고
    • Lessons learned from the development of oral calcitonin: The first tablet formulation of a protein in phase III clinical trials
    • Karsdal MA, Henriksen K, Bay-Jensen AC, et al. Lessons learned from the development of oral calcitonin: the first tablet formulation of a protein in phase III clinical trials. J Clin Pharmacol 2011;51:460-471.
    • (2011) J Clin Pharmacol , vol.51 , pp. 460-471
    • Karsdal, M.A.1    Henriksen, K.2    Bay-Jensen, A.C.3
  • 30
    • 79954463259 scopus 로고    scopus 로고
    • Altered estrogen receptor expression in skeletal muscle and adipose tissue of female rats fed a high-fat diet
    • Gorres BK, Bomhoff GL, Gupte AA, Geiger PC. Altered estrogen receptor expression in skeletal muscle and adipose tissue of female rats fed a high-fat diet. J Appl Physiol 2011;110:1046-1053.
    • (2011) J Appl Physiol , vol.110 , pp. 1046-1053
    • Gorres, B.K.1    Bomhoff, G.L.2    Gupte, A.A.3    Geiger, P.C.4
  • 31
    • 0037532400 scopus 로고    scopus 로고
    • The estrogen antagonist EM-652 and dehydroepiandrosterone prevent diet- and ovariectomy-induced obesity
    • Lemieux C, Picard F, Labrie F, Richard D, Deshaies Y. The estrogen antagonist EM-652 and dehydroepiandrosterone prevent diet- and ovariectomy-induced obesity. Obes Res 2003;11:477-490.
    • (2003) Obes Res , vol.11 , pp. 477-490
    • Lemieux, C.1    Picard, F.2    Labrie, F.3    Richard, D.4    Deshaies, Y.5
  • 33
    • 0036676004 scopus 로고    scopus 로고
    • Bioavailability and biological efficacy of a new oral formulation of salmon calcitonin in healthy volunteers
    • Buclin T, Cosma RM, Burckhardt P, Azria M, Attinger M. Bioavailability and biological efficacy of a new oral formulation of salmon calcitonin in healthy volunteers. J Bone Miner Res 2002;17:1478-1485.
    • (2002) J Bone Miner Res , vol.17 , pp. 1478-1485
    • Buclin, T.1    Cosma, R.M.2    Burckhardt, P.3    Azria, M.4    Attinger, M.5
  • 34
    • 16644391022 scopus 로고    scopus 로고
    • Safety and efficacy of a novel salmon calcitonin (sCT) technology-based oral formulation in healthy postmenopausal women: Acute and 3-month effects on biomarkers of bone turnover
    • Tanko LB, Bagger YZ, Alexandersen P, et al. Safety and efficacy of a novel salmon calcitonin (sCT) technology-based oral formulation in healthy postmenopausal women: acute and 3-month effects on biomarkers of bone turnover. J Bone Miner Res 2004;19:1531-1538.
    • (2004) J Bone Miner Res , vol.19 , pp. 1531-1538
    • Tanko, L.B.1    Bagger, Y.Z.2    Alexandersen, P.3
  • 35
    • 23844459965 scopus 로고    scopus 로고
    • Oral salmon calcitonin induced suppression of urinary collagen type II degradation in postmenopausal women: A new potential treatment of osteoarthritis
    • Bagger YZ, Tanko LB, Alexandersen P, et al. Oral salmon calcitonin induced suppression of urinary collagen type II degradation in postmenopausal women: a new potential treatment of osteoarthritis. Bone 2005;37:425-430.
    • (2005) Bone , vol.37 , pp. 425-430
    • Bagger, Y.Z.1    Tanko, L.B.2    Alexandersen, P.3
  • 36
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and A-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and A-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 37
    • 0034972374 scopus 로고    scopus 로고
    • The anorectic effect of a chronic peripheral infusion of amylin is abolished in area postrema/nucleus of the solitary tract (AP/NTS) lesioned rats
    • Lutz TA, Mollet A, Rushing PA, Riediger T, Scharrer E. The anorectic effect of a chronic peripheral infusion of amylin is abolished in area postrema/nucleus of the solitary tract (AP/NTS) lesioned rats. Int J Obes Relat Metab Disord 2001;25:1005-1011.
    • (2001) Int J Obes Relat Metab Disord , vol.25 , pp. 1005-1011
    • Lutz, T.A.1    Mollet, A.2    Rushing, P.A.3    Riediger, T.4    Scharrer, E.5
  • 38
    • 77953707385 scopus 로고    scopus 로고
    • Brainstem mechanisms of amylin-induced anorexia
    • Potes CS, Lutz TA. Brainstem mechanisms of amylin-induced anorexia. Physiol Behav 2010;100:511-518.
    • (2010) Physiol Behav , vol.100 , pp. 511-518
    • Potes, C.S.1    Lutz, T.A.2
  • 39
    • 57249111939 scopus 로고    scopus 로고
    • Isoflavone regulates lipid metabolism via expression of related genes in OVX rats fed on a high-fat diet
    • Na XL, Ezaki J, Sugiyama F, Cui HB, Ishimi Y. Isoflavone regulates lipid metabolism via expression of related genes in OVX rats fed on a high-fat diet. Biomed Environ Sci 2008;21:357-364.
    • (2008) Biomed Environ Sci , vol.21 , pp. 357-364
    • Na, X.L.1    Ezaki, J.2    Sugiyama, F.3    Cui, H.B.4    Ishimi, Y.5
  • 40
    • 0035658654 scopus 로고    scopus 로고
    • Amylin potently activates AP neurons possibly via formation of the excitatory second messenger cGMP
    • Riediger T, Schmid HA, Lutz T, Simon E. Amylin potently activates AP neurons possibly via formation of the excitatory second messenger cGMP. Am J Physiol Regul Integr Comp Physiol 2001;281:R1833-R1843.
    • (2001) Am J Physiol Regul Integr Comp Physiol , vol.281
    • Riediger, T.1    Schmid, H.A.2    Lutz, T.3    Simon, E.4
  • 41
    • 84864696462 scopus 로고    scopus 로고
    • Oral salmon calcitonin attenuates hyperglycaemia and preserves pancreatic A-cell area and function in Zucker diabetic fatty rats
    • Feigh M, Andreassen KV, Neutzsky-Wulff AV, et al. Oral salmon calcitonin attenuates hyperglycaemia and preserves pancreatic A-cell area and function in Zucker diabetic fatty rats. Br J Pharmacol 2012; 167:151-163.
    • (2012) Br J Pharmacol , vol.167 , pp. 151-163
    • Feigh, M.1    Andreassen, K.V.2    Neutzsky-Wulff, A.V.3
  • 42
    • 0033533161 scopus 로고    scopus 로고
    • Pharmacological characterisation of amylin-related peptides activating subfornical organ neurones
    • Riediger T, Schmid HA, Young AA, Simon E. Pharmacological characterisation of amylin-related peptides activating subfornical organ neurones. Brain Res 1999;837:161-168.
    • (1999) Brain Res , vol.837 , pp. 161-168
    • Riediger, T.1    Schmid, H.A.2    Young, A.A.3    Simon, E.4
  • 44
    • 9444243357 scopus 로고    scopus 로고
    • Characterization of the resistance to the anorectic and endocrine effects of leptin in obesity-prone and obesity-resistant rats fed a high-fat diet
    • Tulipano G, Vergoni AV, Soldi D, Muller EE, Cocchi D. Characterization of the resistance to the anorectic and endocrine effects of leptin in obesity-prone and obesity-resistant rats fed a high-fat diet. J Endocrinol 2004;183:289-298.
    • (2004) J Endocrinol , vol.183 , pp. 289-298
    • Tulipano, G.1    Vergoni, A.V.2    Soldi, D.3    Muller, E.E.4    Cocchi, D.5
  • 45
    • 80055032330 scopus 로고    scopus 로고
    • Glucoregulatory effects and prolonged duration of action of davalintide: A novel amylinomimetic peptide
    • Mack CM, Smith PA, Athanacio JR, et al. Glucoregulatory effects and prolonged duration of action of davalintide: a novel amylinomimetic peptide. Diabetes Obes Metab 2011;13:1105-1113.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 1105-1113
    • Mack, C.M.1    Smith, P.A.2    Athanacio, J.R.3
  • 46
    • 0042167233 scopus 로고    scopus 로고
    • Pramlintide as an adjunct to insulin therapy improves long-term glycemic and weight control in patients with type 2 diabetes: A 1-year randomized controlled trial
    • Hollander PA, Levy P, Fineman MS, et al. Pramlintide as an adjunct to insulin therapy improves long-term glycemic and weight control in patients with type 2 diabetes: a 1-year randomized controlled trial. Diabetes Care 2003;26:784-790.
    • (2003) Diabetes Care , vol.26 , pp. 784-790
    • Hollander, P.A.1    Levy, P.2    Fineman, M.S.3
  • 47
    • 0019135303 scopus 로고
    • Role of ovarian hormones in the long-term control of glucose homeostasis. Effects of insulin secretion
    • Bailey CJ, Ahmed-Sorour H. Role of ovarian hormones in the long-term control of glucose homeostasis. Effects of insulin secretion. Diabetologia 1980;19:475-481.
    • (1980) Diabetologia , vol.19 , pp. 475-481
    • Bailey, C.J.1    Ahmed-Sorour, H.2
  • 48
    • 66449105068 scopus 로고    scopus 로고
    • Estrogens protect against high-fat diet-induced insulin resistance and glucose intolerance in mice
    • Riant E, Waget A, Cogo H, Arnal JF, Burcelin R, Gourdy P. Estrogens protect against high-fat diet-induced insulin resistance and glucose intolerance in mice. Endocrinology 2009;150:2109-2117.
    • (2009) Endocrinology , vol.150 , pp. 2109-2117
    • Riant, E.1    Waget, A.2    Cogo, H.3    Arnal, J.F.4    Burcelin, R.5    Gourdy, P.6
  • 49
    • 80054052492 scopus 로고    scopus 로고
    • Amylin effect in extrapancreatic tissues participating in glucose homeostasis, in normal, insulinresistant and type 2 diabetic state
    • Moreno P, Acitores A, Gutierrez-Rojas I, et al. Amylin effect in extrapancreatic tissues participating in glucose homeostasis, in normal, insulinresistant and type 2 diabetic state. Peptides 2011;32:2077-2085.
    • (2011) Peptides , vol.32 , pp. 2077-2085
    • Moreno, P.1    Acitores, A.2    Gutierrez-Rojas, I.3
  • 50
    • 77954250537 scopus 로고    scopus 로고
    • The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action
    • Hare KJ, Vilsboll T, Asmar M, Deacon CF, Knop FK, Holst JJ. The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action. Diabetes 2010; 59:1765-1770.
    • (2010) Diabetes , vol.59 , pp. 1765-1770
    • Hare, K.J.1    Vilsboll, T.2    Asmar, M.3    Deacon, C.F.4    Knop, F.K.5    Holst, J.J.6
  • 51
    • 57649234120 scopus 로고    scopus 로고
    • The incretin system and its role in type 2 diabetes mellitus
    • Holst JJ, Vilsboll T, Deacon CF. The incretin system and its role in type 2 diabetes mellitus. Mol Cell Endocrinol 2009;297:127-136.
    • (2009) Mol Cell Endocrinol , vol.297 , pp. 127-136
    • Holst, J.J.1    Vilsboll, T.2    Deacon, C.F.3
  • 52
    • 38549144692 scopus 로고    scopus 로고
    • Selective 5-HT6 receptor ligands: Progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders
    • Heal DJ, Smith SL, Fisas A, Codony X, Buschmann H. Selective 5-HT6 receptor ligands: progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders. Pharmacol Ther 2008;117:207-231.
    • (2008) Pharmacol Ther , vol.117 , pp. 207-231
    • Heal, D.J.1    Smith, S.L.2    Fisas, A.3    Codony, X.4    Buschmann, H.5
  • 53
    • 33749364395 scopus 로고    scopus 로고
    • Chronic 5-HT6 receptor modulation by E-6837 induces hypophagia and sustained weight loss in diet-induced obese rats
    • Fisas A, Codony X, Romero G, et al. Chronic 5-HT6 receptor modulation by E-6837 induces hypophagia and sustained weight loss in diet-induced obese rats. Br J Pharmacol 2006;148:973-983.
    • (2006) Br J Pharmacol , vol.148 , pp. 973-983
    • Fisas, A.1    Codony, X.2    Romero, G.3
  • 54
    • 79960566052 scopus 로고    scopus 로고
    • Differential effects of various fish proteins in altering body weight, adiposity, inflammatory status, and insulin sensitivity in high-fat-fed rats
    • Pilon G, Ruzzin J, Rioux LE, et al. Differential effects of various fish proteins in altering body weight, adiposity, inflammatory status, and insulin sensitivity in high-fat-fed rats. Metabolism 2011;60:1122-1130.
    • (2011) Metabolism , vol.60 , pp. 1122-1130
    • Pilon, G.1    Ruzzin, J.2    Rioux, L.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.