Antimycobacterials from Lovage root (Ligusticum officinale Koch)

Phytotherapy Research

Volumn 27, Issue 7, 2013, Pages 993-998

  Guzman, Juan David ^a,b   Evangelopoulos, Dimitrios ^a   Gupta, Antima ^a   Prieto, Jose M ^b   Gibbons, Simon ^b   Bhakta, Sanjib ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

prethapsenol; cytotoxicity; Ligusticum officinale Koch; Lovage; tuberculosis

Indexed keywords

3 BUTYLPHTHALIDE; ALPHA PRETHAPSENOL; BERGAPTEN; BUTYLIDENEPHTHALIDE; FALCARINDIOL; HEXANE; LEVISTOLIDE A; LIGUSTICUM OFFICINALE EXTRACT; LIGUSTILIDE; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; PSORALEN; SESQUITERPENE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ANTIMYCOBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIOSTASIS; BIOASSAY; CHROMATOGRAPHY; COLONY FORMING UNIT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG POTENCY; GROWTH INHIBITION; LIGUSTICUM; LIGUSTICUM OFFICINALE; MAMMAL CELL; MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; MOUSE; MYCOBACTERIUM; MYCOBACTERIUM BOVIS; MYCOBACTERIUM SMEGMATIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYTOCHEMISTRY; PLANT ROOT; SOLVENT EXTRACTION;

Α-PRETHAPSENOL; CYTOTOXICITY; LIGUSTICUM OFFICINALE KOCH; LOVAGE; TUBERCULOSIS;

4-BUTYROLACTONE; ANIMALS; ANTIBIOTICS, ANTITUBERCULAR; CYTOTOXINS; DIYNES; FATTY ALCOHOLS; LIGUSTICUM; MACROPHAGES; MICE; MYCOBACTERIUM BOVIS; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; PSORALENS; SESQUITERPENES;

CNIDIUM OFFICINALE; CORYNEBACTERINEAE; LIGUSTICUM; MAMMALIA; MURINAE; MYCOBACTERIUM BOVIS BCG; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS;

EID: 84879893011     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4823     Document Type: Article

References (29)

1. Andrews AC,. 1941. Alimentary use of Lovage in the Classical period. Isis 33: 514-518.
2. Ashforth EJ, Fu C, Liu X, et al,. 2010. Bioprospecting for antituberculosis leads from microbial metabolites. Nat Prod Rep 27: 1709-1719.
3. Beck JJ, Chou S-C,. 2007. The structural diversity of phthalides from the Apiaceae. J Nat Prod 70: 891-900.
4. Beck JJ, Stermitz FR,. 1995. Addition of methyl thioglycolate and benzylamine to (Z)-ligustilide, a bioactive unsaturated lactone constituent of several herbal medicines. An improved synthesis of (Z)-ligustilide. J Nat Prod 58: 1047-1055.
5. Cégiéla-Carlioz P, Bessière J-M, David B, Mariotte A-M, Gibbons S, Dijoux-Franca M-G,. 2005. Modulation of multi-drug resistance (MDR) in Staphylococcus aureus by Osha (Ligusticum porteri L., Apiaceae) essential oil compounds. Flavour Frag J 20: 671-675.
6. Chen J-J, Chou T-H, Peng C-F, Chen I-S, Yang S-Z,. 2007. Antitubercular dihydroagarofuranoid sesquiterpenes from the roots of Microtropis fokienensis. J Nat Prod 70: 202-205.
7. Chiang C-C, Cheng M-J, Peng C-F, Huang H-Y, Chen I-S,. 2010. A novel dimeric coumarin analog and antimycobacterial constituents from Fatoua pilosa. Chem Biodivers 7: 1728-1736.
8. Cool LG, Vermillion KE, Takeoka GR, Wong RY,. 2010. Irregular sesquiterpenoids from Ligusticum grayi roots. Phytochemistry 71: 1545-1557.
9. Deng S, Wang Y, Inui T, et al,. 2008. Anti-TB polyynes from the roots of Angelica sinensis. Phytother Res 22: 878-882.
10. Evangelopoulos D, Bhakta S,. 2010. Rapid methods for testing inhibitors of mycobacterial growth. Antibiotic Resistance Protocols, Methods in Molecular Biology 642: 279.
11. Fischer NH, Lu T, Cantrell CL, Castaneda-Acosta J, Quijano L, Franzblau SG,. 1998. Antimycobacterial evaluation of germacranolides in honour of professor G.H. Neil Towers 75th birthday. Phytochemistry 49: 559-564.
12. Gupta A, Bhakta S,. 2012. An integrated surrogate model for screening of drugs against Mycobacterium tuberculosis. J Antimicrob Chemother 67: 1380-1391.
13. Guzman JD, Gupta A, Bucar F, Gibbons S, Bhakta S,. 2012. Antimycobacterials from natural sources: ancient times, antibiotic era and novel scaffolds. Front Biosci 17: 1861-1881.
14. Kan WLT, Cho CH, Rudd JA, Lin G,. 2008. Study of the anti-proliferative effects and synergy of phthalides from Angelica sinensis on colon cancer cells. J Ethnopharmacol 120: 36-43.
15. Kaouadji M, De Pachtere F, Pouget C, Chulia AJ, Lavaitte S,. 1986. Three additional phthalide derivatives, an epoxymonomer and two dimers, from Ligusticum wallichii rhizomes. J Nat Prod 49: 872-877.
16. Lechner D, Stavri M, Oluwatuyi M, Pereda-Miranda R, Gibbons S,. 2004. The anti-staphylococcal activity of Angelica dahurica (Bai Zhi). Phytochemistry 65: 331-335.
17. Masuda T, Takasugi M, Anetai M,. 1998. Psoralen and other linear furanocoumarins as phytoalexins in Glehnia littoralis. Phytochemistry 47: 13-16.
18. Miyazawa M, Tsukamoto T, Anzai J, Ishikawa Y,. 2004. Insecticidal effect of phthalides and furanocoumarins from Angelica acutiloba against Drosophila melanogaster. J Agric Food Chem 52: 4401-4405.
19. Newman DJ, Cragg GM,. 2012. Natural products as sources of new drugs over the 30 years from 1981 to 2010. J Nat Prod 75: 311-335.
20. Rajab MS, Cantrell CL, Franzblau SG, Fischer NH,. 1998. Antimycobacterial activity of (E)-phytol and derivatives: A preliminary structure-activity study. Planta Med 64: 2-4.
21. Rolfe MD, Rice CJ, Lucchini S, et al,. 2012. Lag phase is a distinct growth phase that prepares bacteria for exponential growth and involves transient metal accumulation. J Bacteriol 194: 686-701.
22. Schinkovitz A, Pro SM, Main M, et al,. 2008a. Dynamic nature of the ligustilide complex. J Nat Prod 71: 1604-1611.
23. Schinkovitz A, Stavri M, Gibbons S, Bucar F,. 2008b. Antimycobacterial polyacetylenes from Levisticum officinale. Phytother Res 22: 681-684.
24. Toulemonde B, Paul F, Noleau I,. 1987. Phtalides from Lovage (L. officinale Koch). In Flavour Science and Technology, Martens M, Dalett A, Russwurm H, (eds). John Wiley and Sons: New York; 89-94.
25. Vongvanich N, Kittakoop P, Charoenchai P, Intamas S, Sriklung K, Thebtaranonth Y,. 2006. Antiplasmodial, antimycobacterial, and cytotoxic principles from Camchaya calcarea. Planta Med 72: 1427-1430.
26. WHO. 2011. Global tuberculosis control WHO report 1-8.
27. Wu X-m, Qian Z-m, Zhu L, et al,. 2011. Neuroprotective effect of ligustilide against ischaemia-reperfusion injury via up-regulation of erythropoietin and down-regulation of RTP801. Br J Pharmacol 164: 332-343.
28. Zaini RG, Brandt K, Clench MR, Le Maitre CL,. 2012. Effects of bioactive compounds from carrots (Daucus carota L.), polyacetylenes, beta-carotene and lutein on human lymphoid leukaemia cells. Anticancer Agents Med Chem 12: 640-652.
29. Zschocke S, Liu J-H, Stuppner H, Bauer R,. 1998. Comparative study of roots of Angelica sinensis and related umbelliferous drugs by thin layer chromatography, high-performance liquid chromatography, and liquid chromatography-mass spectrometry. Phytochem Anal 9: 283-290.