The clinical and histological response of HIV-associated kidney disease to antiretroviral therapy in South Africans

Nephrology Dialysis Transplantation

Volumn 28, Issue 6, 2013, Pages 1543-1554

  Fabian, June ^a,b   Naicker, Saraladevi ^b   Goetsch, Stewart ^b   Venter, Willem Daniel Francois ^b  

^a Sunninghill Hospital   (South Africa)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Antiretroviral therapy; HIV; HIV associated nephropathy; Renal histopathology

Indexed keywords

ANTIRETROVIRUS AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; EFAVIRENZ; HYDROCHLOROTHIAZIDE; LAMIVUDINE; LOPINAVIR PLUS RITONAVIR; NEVIRAPINE; PREDNISONE; STAVUDINE; ZIDOVUDINE;

ADULT; ARTICLE; CD4 LYMPHOCYTE COUNT; CLINICAL ARTICLE; COMORBIDITY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; GLOMERULONEPHRITIS; GLOMERULUS FILTRATION RATE; HIV ASSOCIATED NEPHROPATHY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; HYPERTENSION; IMMUNE COMPLEX DISEASE; INTERSTITIAL NEPHRITIS; KIDNEY BIOPSY; KIDNEY HYPERTROPHY; KIDNEY TUBULE ACIDOSIS; MACROCYTIC ANEMIA; MALE; MICROALBUMINURIA; PNEUMOCYSTIS PNEUMONIA; PRIORITY JOURNAL; PROTEINURIA; SOUTH AFRICA; VIRUS LOAD;

ANTIRETROVIRAL THERAPY; HIV; HIV-ASSOCIATED NEPHROPATHY; RENAL HISTOPATHOLOGY;

ADOLESCENT; ADULT; AGED; AIDS-ASSOCIATED NEPHROPATHY; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; BIOPSY; FEMALE; FOLLOW-UP STUDIES; GLOMERULAR FILTRATION RATE; HIV INFECTIONS; HIV-1; HUMANS; KIDNEY DISEASES; MALE; MIDDLE AGED; PROGNOSIS; PROSPECTIVE STUDIES; RISK FACTORS; SOUTH AFRICA; SURVIVAL RATE; YOUNG ADULT;

EID: 84879857547     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gft010     Document Type: Article

References (15)

1. Pardo V, Aldana M, Colton RM et al. Glomerular lesions in the acquired immunodeficiency syndrome. Ann Intern Med 1984; 101: 429-434
2. Wyatt CM, Meliambro K, Klotman PE. Recent progress in HIVassociated nephropathy. Annu Rev Med 2012; 63: 147-159 Epub 2011/09/06
3. Han TM, Naicker S, Ramdial PK et al. A cross-sectional study of HIV-seropositive patients with varying degrees of proteinuria in South Africa. Kidney Int 2006; 69: 2243-2250
4. Gerntholtz TE, Goetsch SJ, Katz I. HIV-related nephropathy: a South African perspective. Kidney Int 2006; 69: 1885-1891
5. Okpechi I, Swanepoel C, Duffield M et al. Patterns of renal disease in Cape Town South Africa: a 10-year review of a singlecentre renal biopsy database. Nephrol Dial Transplant 2011; 26: 1853-1861
6. Fabian J, Naicker S, Venter WD et al. Urinary screening abnormalities in antiretroviral-naive HIV-infected outpatients and implications for management-A single-center study in South Africa. Ethn Dis 2009; 19: S1-80-S1-85
7. Cockroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976; 16: 31-41
8. Klahr S. The Modification of Diet in Renal Disease Study. N Engl J Med 1989; 320: 864-866
9. National Department of Health South Africa. National Antiretroviral Treatment Guidelines. Jacana, 2004
10. Forna F, Liechty CA, Solberg P et al. Clinical toxicity of highly active antiretroviral therapy in a home-based AIDS care program in rural Uganda. J Acquir Immune Defic Syndr 2007; 44: 456-462
11. Kalayjian RC, Franceschini N, Gupta SK et al. Suppression of HIV-1 replication by antiretroviral therapy improves renal function in persons with low CD4 cell counts and chronic kidney disease. AIDS 2008; 22: 481-487
12. Peters PJ, Moore DM, Mermin J et al. Antiretroviral therapy improves renal function among HIV-infected Ugandans. Kidney Int 2008; 74: 925-929
13. Szczech LA, Gupta SK, Habash R et al. The clinical epidemiology and course of the spectrum of renal diseases associated with HIV infection. Kidney Int 2004; 66: 1145-1152
14. Bige N, Lanternier F, Viard JP et al. Presentation of HIV-associated nephropathy and outcome in HAART-treated patients. Nephrol Dial Transplant 2012; 27: 1114-1121
15. Kimmel PL, Ferreira-Centeno A, Farkas-Szallasi T et al. Viral DNA in microdissected renal biopsy tissue from HIV infected patients with nephrotic syndrome. Kidney Int 1993; 43: 1347-1352