Molecular epidemiology of canine GM1 gangliosidosis in the Shiba Inu breed in Japan: Relationship between regional prevalence and carrier frequency

BMC Veterinary Research

Volumn 9, Issue , 2013, Pages

  Uddin, Mohammad M ^a,b   Arata, Sayaka ^c   Takeuchi, Yukari ^c   Chang, Hye Sook ^a   Mizukami, Keijiro ^a   Yabuki, Akira ^a   Rahman, Mohammad M ^a,b   Kohyama, Moeko ^a   Hossain, Mohammad A ^b   Takayama, Kenji ^d   Yamato, Osamu ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b Chittagong Government Veterinary College   (Bangladesh)

^c UNIVERSITY OF TOKYO   (Japan)

^d Hayashiya Animal Medical Center   (Japan)

Author keywords

Canine Inherited Disease; GM1 Gangliosidosis; Molecular Epidemiology; Shiba Inu Dog

Indexed keywords

CANIS FAMILIARIS; ZOYSIA JAPONICA;

ANIMAL; BREEDING; DOG; DOG DISEASES; GANGLIOSIDOSIS, GM1; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HETEROZYGOTE; JAPAN; MOLECULAR EPIDEMIOLOGY; PEDIGREE; PREVALENCE; RETROSPECTIVE STUDY; VETERINARY; ANIMAL DISEASE; ARTICLE; DOG DISEASE; GM1 GANGLIOSIDOSIS;

ANIMALS; BREEDING; DOG DISEASES; DOGS; GANGLIOSIDOSIS, GM1; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HETEROZYGOTE; JAPAN; MOLECULAR EPIDEMIOLOGY; PEDIGREE; PREVALENCE; RETROSPECTIVE STUDIES;

EID: 84879826464     PISSN: None     EISSN: 17466148     Source Type: Journal    
DOI: 10.1186/1746-6148-9-132     Document Type: Article

References (16)

1. Suzuki Y, Oshima A, Nanba E. β-Galactosidase deficiency (β-galactosidosis): GM1 gangliosidosis and Morquio B disease. The metabolic and molecular bases of inherited disease 2001, 3775-3809. New York: McGraw-Hill, Scriver CR, Beaudet AL, Sly WS, Valle D, 8.
2. Yamato O, Ochiai K, Masuoka Y, Hayashida E, Tajima M, Omae S, Iijima M, Umemura T, Maede Y. GM1 gangliosidosis in Shiba dogs. Vet Rec 2000, 146:493-496. 10.1136/vr.146.17.493, 10887996.
3. Yamato O, Endoh D, Kobayashi A, Masuoka Y, Yonemura M, Hatakeyama A, Satoh H, Tajima M, Yamasaki M, Maede Y. A novel mutation in the gene for canine acid β-galactosidase that causes GM1-gangliosidosis in Shiba dogs. J Inherited Metab Dis 2002, 25:525-526. 10.1023/A:1021280007739, 12555949.
4. Chang HS, Arai T, Yabuki A, Hossain MA, Rahman MM, Mizukami K, Yamato O. Rapid and reliable genotyping technique for GM1 gangliosidosis in Shiba dogs by real-time polymerase chain reaction with TaqMan minor groove binder probes. J Vet Diagn Invest 2010, 22:234-237. 10.1177/104063871002200210, 20224082.
5. Yamato O, Jo EO, Shoda T, Yamasaki M, Maede Y. Rapid and simple mutation screening of GM1-gangliosidosis in Shiba dogs by direct amplification of deoxyribonucleic acid from various forms of canine whole-blood specimens. J Vet Diagn Invest 2004, 16:469-472. 10.1177/104063870401600520, 15460336.
6. Hasegawa D, Yamato O, Nakamoto Y, Ozawa T, Yabuki A, Itamoto K, Kuwabara T, Fujita M, Takahashi K, Mizoguchi S, Orima H. Serial MRI features of canine GM1 gangliosidosis: a possible imaging biomarker for diagnosis and progression of the disease. Sci World J 2012, 2012:250197.
7. Yamato O, Masuoka Y, Yonemura M, Hatakeyama A, Satoh H, Kobayashi A, Nakayama M, Asano T, Shoda T, Yamasaki M, Ochiai K, Umemura T, Maede Y. Clinical and clinico-pathologic characteristics of Shiba dogs with a deficiency of lysosomal acid β-galactosidase: a canine model of human GM1-gangliosidosis. J Vet Med Sci 2003, 65:213-217. 10.1292/jvms.65.213, 12655116.
8. Satoh H, Yamato O, Asano T, Yonemura M, Yamauchi T, Hasegawa D, Orima H, Arai T, Yamasaki M, Maede Y. Cerebrospinal fluid biomarkers showing neurodegeneration in dogs with GM1 gangliosidosis: possible use for assessment of a therapeutic regimen. Brain Res 2007, 1133:200-208.
9. Yamato O, Jo EO, Chang HS, Satoh H, Shoda T, Sato R, Uechi M, Kawasaki N, Naito Y, Yamasaki M, Maede Y, Arai T. Molecular screening canine GM1 gangliosidosis using blood smear specimens after prolonged storage: detection of carriers among Shiba dogs in northern Japan. J Vet Diagn Invest 2008, 20:68-71. 10.1177/104063870802000113, 18182512.
10. Baker HJ, Smith BF, Martin DR, Foureman P. Molecular diagnosis of gangliosidoses: a model for elimination of inherited diseases in pure breeds. Consultations in feline internal medicine 2001, 615-620. Philadelphia: W.B. Saunders, August JR, 4.
11. Yamato O, Funk H, Kawahara N, Funková M, Entlerová Z, Petrusová H, Hayashi D, Satoh H, Yamasaki M, Maede Y, Yabuki A, Arai T. Mutation screening of canine GM1 gangliosidosis for preventive measures: absence of the mutant allele in breeding Shiba dogs in the Czech Republic. Jpn J Prophylactic Vet Med 2009, 1:63-68.
12. Mizukami K, Chang HS, Yabuki A, Kawamichi T, Kawahara N, Hayashi D, Hossain MA, Rahman MM, Uddin MM, Yamato O. Novel rapid genotyping assays for neuronal ceroid lipofuscinosis in Border Collie dogs and high frequency of the mutant allele in Japan. J Vet Diagn Invest 2011, 23:1131-1139. 10.1177/1040638711425590, 22362793.
13. Alroy J, Orgad U, Ucci AA, Schelling SH, Schunk KL, Warren CD, Raghavan SS, Kolodny EH. Neurovisceral and skeletal GM1 gangliosidosis in dogs with β-galactosidase deficiency. Science 1985, 229:470-472. 10.1126/science.3925555, 3925555.
14. Saunders GK, Wood PA, Myers RK, Shell LG, Carithers R. GM1-gangliosidosis in Portuguese water dogs: pathologic and biochemical findings. Vet Pathol 1988, 25:265-269. 10.1177/030098588802500403, 3136586.
15. Müller G, Baumgärtner W, Moritz A, Sewell A, Kustermann-Kuhn B. Biochemical findings in a breeding colony of Alaskan huskies suffering from GM1-gangliosidosis. J Inherited Metab Dis 1998, 21:430-431. 10.1023/A:1005323212440, 9700604.
16. Mizukami K, Kawamichi T, Koie H, Tamura S, Matsunaga S, Imamoto S, Saito M, Hasegawa D, Matsuki N, Tamahara S, Sato S, Yabuki A, Chang HS, Yamato O. Neuronal ceroid lipofuscinosis in Border Collie dogs in Japan: clinical molecular epidemiological survey (2000-2011). Sci World J 2012, 2012:383174.