메뉴 건너뛰기




Volumn 97, Issue , 2013, Pages 69-80

Roles of long noncoding RNAs in brain development, functional diversification and neurodegenerative diseases

Author keywords

Expression signature; LncRNA; Neurodegenerative disease; Neuron; Noncoding RNA

Indexed keywords

4 AMINOBUTYRIC ACID; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; COPPER ZINC SUPEROXIDE DISMUTASE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR OPPOSITE STRAND; HUNTINGTIN; LONG UNTRANSLATED RNA; MESSENGER RNA; NATURAL ANTISENSE RNA; NEUROGRANIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHATASE; PHOSPHATASE AND TENSIN HOMOLOGUE INDUCED PUTATIVE KINASE 1; POLYCOMB REPRESSIVE COMPLEX 2; RAD18 PROTEIN; RNA; RNA BINDING PROTEIN; TAR DNA BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DLX5; TRANSCRIPTION FACTOR DLX6; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; UNINDEXED DRUG; UNTRANSLATED RNA;

EID: 84879823671     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2013.06.001     Document Type: Review
Times cited : (331)

References (133)
  • 1
    • 84455169910 scopus 로고    scopus 로고
    • Identification of novel GDNF isoforms and cis-antisense GDNFOS gene and their regulation in human middle temporal gyrus of Alzheimer disease
    • Airavaara M., Pletnikova O., Doyle M.E., Zhang Y.E., Troncoso J.C., Liu Q.R. Identification of novel GDNF isoforms and cis-antisense GDNFOS gene and their regulation in human middle temporal gyrus of Alzheimer disease. Journal of Biological Chemistry 2011, 286:45093-45102.
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 45093-45102
    • Airavaara, M.1    Pletnikova, O.2    Doyle, M.E.3    Zhang, Y.E.4    Troncoso, J.C.5    Liu, Q.R.6
  • 4
    • 37349043972 scopus 로고    scopus 로고
    • Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends
    • Azzalin C.M., Reichenbach P., Khoriauli L., Giulotto E., Lingner J. Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. Science 2007, 318:798-801.
    • (2007) Science , vol.318 , pp. 798-801
    • Azzalin, C.M.1    Reichenbach, P.2    Khoriauli, L.3    Giulotto, E.4    Lingner, J.5
  • 7
    • 0025809321 scopus 로고
    • Parental imprinting of the mouse H19 gene
    • Bartolomei M.S., Zemel S., Tilghman S.M. Parental imprinting of the mouse H19 gene. Nature 1991, 351:153-155.
    • (1991) Nature , vol.351 , pp. 153-155
    • Bartolomei, M.S.1    Zemel, S.2    Tilghman, S.M.3
  • 11
    • 85027951676 scopus 로고    scopus 로고
    • Functions of noncoding RNAs in neural development and neurological diseases
    • Bian S., Sun T. Functions of noncoding RNAs in neural development and neurological diseases. Molecular Neurobiology 2011, 44:359-373.
    • (2011) Molecular Neurobiology , vol.44 , pp. 359-373
    • Bian, S.1    Sun, T.2
  • 13
    • 0025863618 scopus 로고
    • Neuropathological staging of Alzheimer-related changes
    • Braak H., Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathologica 1991, 82:239-259.
    • (1991) Acta Neuropathologica , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 14
    • 0025961771 scopus 로고
    • A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome
    • Brown C.J., Ballabio A., Rupert J.L., Lafreniere R.G., Grompe M., Tonlorenzi R., Willard H.F. A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome. Nature 1991, 349:38-44.
    • (1991) Nature , vol.349 , pp. 38-44
    • Brown, C.J.1    Ballabio, A.2    Rupert, J.L.3    Lafreniere, R.G.4    Grompe, M.5    Tonlorenzi, R.6    Willard, H.F.7
  • 17
  • 20
    • 80054756754 scopus 로고    scopus 로고
    • Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions
    • Chu C., Qu K., Zhong F.L., Artandi S.E., Chang H.Y. Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. Molecular Cell 2011, 44:667-678.
    • (2011) Molecular Cell , vol.44 , pp. 667-678
    • Chu, C.1    Qu, K.2    Zhong, F.L.3    Artandi, S.E.4    Chang, H.Y.5
  • 22
    • 80051695536 scopus 로고    scopus 로고
    • A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression
    • Chung D.W., Rudnicki D.D., Yu L., Margolis R.L. A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression. Human Molecular Genetics 2011, 20:3467-3477.
    • (2011) Human Molecular Genetics , vol.20 , pp. 3467-3477
    • Chung, D.W.1    Rudnicki, D.D.2    Yu, L.3    Margolis, R.L.4
  • 25
    • 84856255316 scopus 로고    scopus 로고
    • Bioinformatics tools and novel challenges in long non-coding RNAs (lncRNAs) functional analysis
    • Da S.L., Baldassarre A., Masotti A. Bioinformatics tools and novel challenges in long non-coding RNAs (lncRNAs) functional analysis. International Journal of Molecular Sciences 2012, 13:97-114.
    • (2012) International Journal of Molecular Sciences , vol.13 , pp. 97-114
    • Da, S.L.1    Baldassarre, A.2    Masotti, A.3
  • 32
    • 84868550433 scopus 로고    scopus 로고
    • The C-value paradox, junk DNA and ENCODE
    • Eddy S.R. The C-value paradox, junk DNA and ENCODE. Current Biology 2012, 22:R898-R899.
    • (2012) Current Biology , vol.22
    • Eddy, S.R.1
  • 33
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA. Elements in the human genome
    • ENCODE Project Consortium
    • ENCODE Project Consortium An integrated encyclopedia of DNA. Elements in the human genome. Nature 2012, 489:57-74.
    • (2012) Nature , vol.489 , pp. 57-74
  • 36
    • 33744804277 scopus 로고    scopus 로고
    • The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator
    • Feng J., Bi C., Clark B.S., Mady R., Shah P., Kohtz J.D. The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator. Genes and Development 2006, 20:1470-1484.
    • (2006) Genes and Development , vol.20 , pp. 1470-1484
    • Feng, J.1    Bi, C.2    Clark, B.S.3    Mady, R.4    Shah, P.5    Kohtz, J.D.6
  • 37
    • 0029970008 scopus 로고    scopus 로고
    • Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus
    • Figurov A., Pozzo-Miller L.D., Olafsson P., Wang T., Lu B. Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature 1996, 381:706-709.
    • (1996) Nature , vol.381 , pp. 706-709
    • Figurov, A.1    Pozzo-Miller, L.D.2    Olafsson, P.3    Wang, T.4    Lu, B.5
  • 39
    • 77953647392 scopus 로고    scopus 로고
    • A novel hypothesis for Alzheimer disease based on neuronal tetraploidy induced by p75 (NTR)
    • Frade J.M., Lopez-Sanchez N. A novel hypothesis for Alzheimer disease based on neuronal tetraploidy induced by p75 (NTR). Cell Cycle 2010, 9:1934-1941.
    • (2010) Cell Cycle , vol.9 , pp. 1934-1941
    • Frade, J.M.1    Lopez-Sanchez, N.2
  • 41
    • 0031243489 scopus 로고    scopus 로고
    • RC3/neurogranin, a postsynaptic calpacitin for setting the response threshold to calcium influxes
    • Gerendasy D.D., Sutcliffe J.G. RC3/neurogranin, a postsynaptic calpacitin for setting the response threshold to calcium influxes. Molecular Neurobiology 1997, 15:131-163.
    • (1997) Molecular Neurobiology , vol.15 , pp. 131-163
    • Gerendasy, D.D.1    Sutcliffe, J.G.2
  • 42
    • 79960077511 scopus 로고    scopus 로고
    • Association of the brain-derived neurotrophic factor Val66Met polymorphism with hippocampus volumes in drug-free depressed patients
    • Gonul A.S., Kitis O., Eker M.C., Eker O.D., Ozan E., Coburn K. Association of the brain-derived neurotrophic factor Val66Met polymorphism with hippocampus volumes in drug-free depressed patients. World Journal of Biological Psychiatry 2011, 12:110-118.
    • (2011) World Journal of Biological Psychiatry , vol.12 , pp. 110-118
    • Gonul, A.S.1    Kitis, O.2    Eker, M.C.3    Eker, O.D.4    Ozan, E.5    Coburn, K.6
  • 43
    • 44649134044 scopus 로고    scopus 로고
    • Epigenetic codes in cognition and behaviour
    • Graff J., Mansuy I.M. Epigenetic codes in cognition and behaviour. Behavioural Brain Research 2008, 192:70-87.
    • (2008) Behavioural Brain Research , vol.192 , pp. 70-87
    • Graff, J.1    Mansuy, I.M.2
  • 44
    • 84875275808 scopus 로고    scopus 로고
    • On the immortality of television sets: "function" in the human genome according to the evolution-free gospel of ENCODE
    • Graur D., Zheng Y., Price N., Azevedo R.B., Zufall R.A., Elhaik E. On the immortality of television sets: "function" in the human genome according to the evolution-free gospel of ENCODE. Genome Biology and Evolution 2013, 5(3):578-590.
    • (2013) Genome Biology and Evolution , vol.5 , Issue.3 , pp. 578-590
    • Graur, D.1    Zheng, Y.2    Price, N.3    Azevedo, R.B.4    Zufall, R.A.5    Elhaik, E.6
  • 45
    • 84877601532 scopus 로고    scopus 로고
    • Comment on "Evidence of abundant purifying selection in humans for recently acquired regulatory functions"
    • Green P., Ewing B. Comment on "Evidence of abundant purifying selection in humans for recently acquired regulatory functions". Science 2013, 340:682.
    • (2013) Science , vol.340 , pp. 682
    • Green, P.1    Ewing, B.2
  • 47
    • 84857066786 scopus 로고    scopus 로고
    • Modular regulatory principles of large non-coding RNAs
    • Guttman M., Rinn J.L. Modular regulatory principles of large non-coding RNAs. Nature 2012, 482:339-346.
    • (2012) Nature , vol.482 , pp. 339-346
    • Guttman, M.1    Rinn, J.L.2
  • 48
    • 0142026157 scopus 로고    scopus 로고
    • Differential activities of Sonic hedgehog mediated by Gli transcription factors define distinct neuronal subtypes in the dorsal thalamus
    • Hashimoto-Torii K., Motoyama J., Hui C.C., Kuroiwa A., Nakafuku M., Shimamura K. Differential activities of Sonic hedgehog mediated by Gli transcription factors define distinct neuronal subtypes in the dorsal thalamus. Mechanisms of Development 2003, 120:1097-1111.
    • (2003) Mechanisms of Development , vol.120 , pp. 1097-1111
    • Hashimoto-Torii, K.1    Motoyama, J.2    Hui, C.C.3    Kuroiwa, A.4    Nakafuku, M.5    Shimamura, K.6
  • 49
    • 78651397147 scopus 로고    scopus 로고
    • Large non-coding RNAs: missing links in cancer?
    • Huarte M., Rinn J.L. Large non-coding RNAs: missing links in cancer?. Human Molecular Genetics 2010, 19:R152-R161.
    • (2010) Human Molecular Genetics , vol.19
    • Huarte, M.1    Rinn, J.L.2
  • 53
    • 84862777038 scopus 로고    scopus 로고
    • Long non-coding RNAs in Huntington's disease neurodegeneration
    • Johnson R. Long non-coding RNAs in Huntington's disease neurodegeneration. Neurobiology of Disease 2012, 46:245-254.
    • (2012) Neurobiology of Disease , vol.46 , pp. 245-254
    • Johnson, R.1
  • 54
    • 0028988240 scopus 로고
    • Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus
    • Kang H., Schuman E.M. Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus. Science 1995, 267:1658-1662.
    • (1995) Science , vol.267 , pp. 1658-1662
    • Kang, H.1    Schuman, E.M.2
  • 57
    • 0037083306 scopus 로고    scopus 로고
    • Critical time-window for NO-cGMP-dependent long-term memory formation after one-trial appetitive conditioning
    • Kemenes I., Kemenes G., Andrew R.J., Benjamin P.R., O'Shea M. Critical time-window for NO-cGMP-dependent long-term memory formation after one-trial appetitive conditioning. Journal of Neuroscience 2002, 22:1414-1425.
    • (2002) Journal of Neuroscience , vol.22 , pp. 1414-1425
    • Kemenes, I.1    Kemenes, G.2    Andrew, R.J.3    Benjamin, P.R.4    O'Shea, M.5
  • 58
    • 0032077680 scopus 로고    scopus 로고
    • Signal transduction molecules at the glutamatergic postsynaptic membrane
    • Kennedy M.B. Signal transduction molecules at the glutamatergic postsynaptic membrane. Brain Research. Brain Research Reviews 1998, 26:243-257.
    • (1998) Brain Research. Brain Research Reviews , vol.26 , pp. 243-257
    • Kennedy, M.B.1
  • 60
    • 0033568856 scopus 로고    scopus 로고
    • Neuronal expression of neural nitric oxide synthase (nNOS) protein is suppressed by an antisense RNA transcribed from an NOS pseudogene
    • Korneev S.A., Park J.H., O'Shea M. Neuronal expression of neural nitric oxide synthase (nNOS) protein is suppressed by an antisense RNA transcribed from an NOS pseudogene. Journal of Neuroscience 1999, 19:7711-7720.
    • (1999) Journal of Neuroscience , vol.19 , pp. 7711-7720
    • Korneev, S.A.1    Park, J.H.2    O'Shea, M.3
  • 61
    • 13944276686 scopus 로고    scopus 로고
    • Timed and targeted differential regulation of nitric oxide synthase (NOS) and anti-NOS genes by reward conditioning leading to long-term memory formation
    • Korneev S.A., Straub V., Kemenes I., Korneeva E.I., Ott S.R., Benjamin P.R., O'Shea M. Timed and targeted differential regulation of nitric oxide synthase (NOS) and anti-NOS genes by reward conditioning leading to long-term memory formation. Journal of Neuroscience 2005, 25:1188-1192.
    • (2005) Journal of Neuroscience , vol.25 , pp. 1188-1192
    • Korneev, S.A.1    Straub, V.2    Kemenes, I.3    Korneeva, E.I.4    Ott, S.R.5    Benjamin, P.R.6    O'Shea, M.7
  • 64
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee R.C., Feinbaum R.L., Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993, 75:843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 66
    • 33745071523 scopus 로고    scopus 로고
    • An endogenous inhibitor of calcium/calmodulin-dependent kinase II is up-regulated during consolidation of fear memory
    • Lepicard E.M., Mizuno K., Antunes-Martins A., von Hertzen L.S., Giese K.P. An endogenous inhibitor of calcium/calmodulin-dependent kinase II is up-regulated during consolidation of fear memory. European Journal of Neuroscience 2006, 23:3063-3070.
    • (2006) European Journal of Neuroscience , vol.23 , pp. 3063-3070
    • Lepicard, E.M.1    Mizuno, K.2    Antunes-Martins, A.3    von Hertzen, L.S.4    Giese, K.P.5
  • 67
    • 34548605504 scopus 로고    scopus 로고
    • Steroid receptor RNA activator (SRA1): unusual bifaceted gene products with suspected relevance to breast cancer
    • Leygue E. Steroid receptor RNA activator (SRA1): unusual bifaceted gene products with suspected relevance to breast cancer. Nuclear Receptor Signaling 2007, 5:e6.
    • (2007) Nuclear Receptor Signaling , vol.5
    • Leygue, E.1
  • 68
    • 42349090351 scopus 로고    scopus 로고
    • Translational control by a small RNA: dendritic BC1 RNA targets the eukaryotic initiation factor 4A helicase mechanism
    • Lin D., Pestova T.V., Hellen C.U., Tiedge H. Translational control by a small RNA: dendritic BC1 RNA targets the eukaryotic initiation factor 4A helicase mechanism. Molecular and Cellular Biology 2008, 28:3008-3019.
    • (2008) Molecular and Cellular Biology , vol.28 , pp. 3008-3019
    • Lin, D.1    Pestova, T.V.2    Hellen, C.U.3    Tiedge, H.4
  • 69
    • 80052536392 scopus 로고    scopus 로고
    • RNA-Seq of human neurons derived from iPS cells reveals candidate long non-coding RNAs involved in neurogenesis and neuropsychiatric disorders
    • Lin M., Pedrosa E., Shah A., Hrabovsky A., Maqbool S., Zheng D., Lachman H.M. RNA-Seq of human neurons derived from iPS cells reveals candidate long non-coding RNAs involved in neurogenesis and neuropsychiatric disorders. PLoS ONE 2011, 6:e23356.
    • (2011) PLoS ONE , vol.6
    • Lin, M.1    Pedrosa, E.2    Shah, A.3    Hrabovsky, A.4    Maqbool, S.5    Zheng, D.6    Lachman, H.M.7
  • 70
    • 79951837277 scopus 로고    scopus 로고
    • Spatiotemporal regulation of multiple overlapping sense and novel natural antisense transcripts at the Nrgn and Camk2n1 gene loci during mouse cerebral corticogenesis
    • Ling K.H., Hewitt C.A., Beissbarth T., Hyde L., Cheah P.S., Smyth G.K., Tan S.S., Hahn C.N., Thomas T., Thomas P.Q., Scott H.S. Spatiotemporal regulation of multiple overlapping sense and novel natural antisense transcripts at the Nrgn and Camk2n1 gene loci during mouse cerebral corticogenesis. Cerebral Cortex 2011, 21:683-697.
    • (2011) Cerebral Cortex , vol.21 , pp. 683-697
    • Ling, K.H.1    Hewitt, C.A.2    Beissbarth, T.3    Hyde, L.4    Cheah, P.S.5    Smyth, G.K.6    Tan, S.S.7    Hahn, C.N.8    Thomas, T.9    Thomas, P.Q.10    Scott, H.S.11
  • 71
    • 84869016176 scopus 로고    scopus 로고
    • Activity-dependent human brain coding/noncoding gene regulatory networks
    • Lipovich L., Dachet F., Cai J., Bagla S., Balan K., Jia H., Loeb J.A. Activity-dependent human brain coding/noncoding gene regulatory networks. Genetics 2012, 192:1133-1148.
    • (2012) Genetics , vol.192 , pp. 1133-1148
    • Lipovich, L.1    Dachet, F.2    Cai, J.3    Bagla, S.4    Balan, K.5    Jia, H.6    Loeb, J.A.7
  • 73
    • 0036513485 scopus 로고    scopus 로고
    • The molecular basis of CaMKII function in synaptic and behavioural memory
    • Lisman J., Schulman H., Cline H. The molecular basis of CaMKII function in synaptic and behavioural memory. Nature Reviews Neuroscience 2002, 3:175-190.
    • (2002) Nature Reviews Neuroscience , vol.3 , pp. 175-190
    • Lisman, J.1    Schulman, H.2    Cline, H.3
  • 75
    • 0026663662 scopus 로고
    • BC200 RNA in normal human neocortex, non-Alzheimer dementia (NAD), and senile dementia of the Alzheimer type (AD)
    • Lukiw W.J., Handley P., Wong L., Crapper M.D. BC200 RNA in normal human neocortex, non-Alzheimer dementia (NAD), and senile dementia of the Alzheimer type (AD). Neurochemical Research 1992, 17:591-597.
    • (1992) Neurochemical Research , vol.17 , pp. 591-597
    • Lukiw, W.J.1    Handley, P.2    Wong, L.3    Crapper, M.D.4
  • 77
    • 34249740942 scopus 로고    scopus 로고
    • A new paradigm for developmental biology
    • Mattick J.S. A new paradigm for developmental biology. Journal of Experimental Biology 2007, 210:1526-1547.
    • (2007) Journal of Experimental Biology , vol.210 , pp. 1526-1547
    • Mattick, J.S.1
  • 78
    • 49649109010 scopus 로고    scopus 로고
    • A discontinuous hammerhead ribozyme embedded in a mammalian messenger RNA
    • Martick M., Horan L.H., Noller H.F., Scott W.G. A discontinuous hammerhead ribozyme embedded in a mammalian messenger RNA. Nature 2008, 454:899-902.
    • (2008) Nature , vol.454 , pp. 899-902
    • Martick, M.1    Horan, L.H.2    Noller, H.F.3    Scott, W.G.4
  • 83
    • 0037447892 scopus 로고    scopus 로고
    • The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord
    • Meyer N.P., Roelink H. The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord. Developmental Biology 2003, 257:343-355.
    • (2003) Developmental Biology , vol.257 , pp. 343-355
    • Meyer, N.P.1    Roelink, H.2
  • 90
    • 0029880012 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthase impairs a distinct form of long-term memory in the honeybee, Apis mellifera
    • Muller U. Inhibition of nitric oxide synthase impairs a distinct form of long-term memory in the honeybee, Apis mellifera. Neuron 1996, 16:541-549.
    • (1996) Neuron , vol.16 , pp. 541-549
    • Muller, U.1
  • 92
    • 79953858658 scopus 로고    scopus 로고
    • No-nonsense functions for long noncoding RNAs
    • Nagano T., Fraser P. No-nonsense functions for long noncoding RNAs. Cell 2011, 145:178-181.
    • (2011) Cell , vol.145 , pp. 178-181
    • Nagano, T.1    Fraser, P.2
  • 94
    • 84856492490 scopus 로고    scopus 로고
    • Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors
    • Ng S.Y., Johnson R., Stanton L.W. Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors. EMBO Journal 2012, 31:522-533.
    • (2012) EMBO Journal , vol.31 , pp. 522-533
    • Ng, S.Y.1    Johnson, R.2    Stanton, L.W.3
  • 98
    • 35748955206 scopus 로고    scopus 로고
    • A natural antisense transcript against Rad18, specifically expressed in neurons and upregulated during beta-amyloid-induced apoptosis
    • Parenti R., Paratore S., Torrisi A., Cavallaro S. A natural antisense transcript against Rad18, specifically expressed in neurons and upregulated during beta-amyloid-induced apoptosis. European Journal of Neuroscience 2007, 26:2444-2457.
    • (2007) European Journal of Neuroscience , vol.26 , pp. 2444-2457
    • Parenti, R.1    Paratore, S.2    Torrisi, A.3    Cavallaro, S.4
  • 100
    • 77953957633 scopus 로고    scopus 로고
    • A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
    • Poliseno L., Salmena L., Zhang J., Carver B., Haveman W.J., Pandolfi P.P. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 2010, 465:1033-1038.
    • (2010) Nature , vol.465 , pp. 1033-1038
    • Poliseno, L.1    Salmena, L.2    Zhang, J.3    Carver, B.4    Haveman, W.J.5    Pandolfi, P.P.6
  • 102
    • 84859512071 scopus 로고    scopus 로고
    • Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis
    • Pokrishevsky E., Grad L.I., Yousefi M., Wang J., Mackenzie I.R., Cashman N.R. Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis. PLoS ONE 2012, 7:e35050.
    • (2012) PLoS ONE , vol.7
    • Pokrishevsky, E.1    Grad, L.I.2    Yousefi, M.3    Wang, J.4    Mackenzie, I.R.5    Cashman, N.R.6
  • 103
    • 35848970761 scopus 로고    scopus 로고
    • The long and the short of RNA maps
    • Ponjavic J., Ponting C.P. The long and the short of RNA maps. Bioessays 2007, 29:1077-1080.
    • (2007) Bioessays , vol.29 , pp. 1077-1080
    • Ponjavic, J.1    Ponting, C.P.2
  • 104
    • 34248162440 scopus 로고    scopus 로고
    • Functionality or transcriptional noise? Evidence for selection within long noncoding RNAs
    • Ponjavic J., Ponting C.P., Lunter G. Functionality or transcriptional noise? Evidence for selection within long noncoding RNAs. Genome Research 2007, 17:556-565.
    • (2007) Genome Research , vol.17 , pp. 556-565
    • Ponjavic, J.1    Ponting, C.P.2    Lunter, G.3
  • 105
    • 70149123708 scopus 로고    scopus 로고
    • Genomic and transcriptional co-localization of protein-coding and long non-coding RNA pairs in the developing brain
    • Ponjavic J., Oliver P.L., Lunter G., Ponting C.P. Genomic and transcriptional co-localization of protein-coding and long non-coding RNA pairs in the developing brain. PLoS Genetics 2009, 5:e1000617.
    • (2009) PLoS Genetics , vol.5
    • Ponjavic, J.1    Oliver, P.L.2    Lunter, G.3    Ponting, C.P.4
  • 106
    • 60149099385 scopus 로고    scopus 로고
    • Evolution and functions of long noncoding RNAs
    • Ponting C.P., Oliver P.L., Reik W. Evolution and functions of long noncoding RNAs. Cell 2009, 136:629-641.
    • (2009) Cell , vol.136 , pp. 629-641
    • Ponting, C.P.1    Oliver, P.L.2    Reik, W.3
  • 107
    • 34547499702 scopus 로고    scopus 로고
    • Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters
    • Pruunsild P., Kazantseva A., Aid T., Palm K., Timmusk T. Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters. Genomics 2007, 90:397-406.
    • (2007) Genomics , vol.90 , pp. 397-406
    • Pruunsild, P.1    Kazantseva, A.2    Aid, T.3    Palm, K.4    Timmusk, T.5
  • 108
    • 81755161589 scopus 로고    scopus 로고
    • Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins
    • Rackham O., Shearwood A.M., Mercer T.R., Davies S.M., Mattick J.S., Filipovska A. Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins. RNA 2011, 17:2085-2093.
    • (2011) RNA , vol.17 , pp. 2085-2093
    • Rackham, O.1    Shearwood, A.M.2    Mercer, T.R.3    Davies, S.M.4    Mattick, J.S.5    Filipovska, A.6
  • 109
    • 77951945884 scopus 로고    scopus 로고
    • The long noncoding RNA RNCR2 directs mouse retinal cell specification
    • Rapicavoli N.A., Poth E.M., Blackshaw S. The long noncoding RNA RNCR2 directs mouse retinal cell specification. BMC Developmental Biology 2010, 10:49.
    • (2010) BMC Developmental Biology , vol.10 , pp. 49
    • Rapicavoli, N.A.1    Poth, E.M.2    Blackshaw, S.3
  • 110
    • 80053172782 scopus 로고    scopus 로고
    • The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activity
    • Rapicavoli N.A., Poth E.M., Zhu H., Blackshaw S. The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activity. Neural Development 2011, 6:32.
    • (2011) Neural Development , vol.6 , pp. 32
    • Rapicavoli, N.A.1    Poth, E.M.2    Zhu, H.3    Blackshaw, S.4
  • 112
    • 84865581126 scopus 로고    scopus 로고
    • The Parkinson's disease-related genes act in mitochondrial homeostasis
    • Sai Y., Zou Z., Peng K., Dong Z. The Parkinson's disease-related genes act in mitochondrial homeostasis. Neuroscience and Biobehavioral Reviews 2012, 36:2034-2043.
    • (2012) Neuroscience and Biobehavioral Reviews , vol.36 , pp. 2034-2043
    • Sai, Y.1    Zou, Z.2    Peng, K.3    Dong, Z.4
  • 115
    • 58049197863 scopus 로고    scopus 로고
    • Huntingtin regulates RE1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) nuclear trafficking indirectly through a complex with REST/NRSF-interacting LIM domain protein (RILP) and dynactin p150 Glued
    • Shimojo M. Huntingtin regulates RE1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) nuclear trafficking indirectly through a complex with REST/NRSF-interacting LIM domain protein (RILP) and dynactin p150 Glued. Journal of Biological Chemistry 2008, 283:34880-34886.
    • (2008) Journal of Biological Chemistry , vol.283 , pp. 34880-34886
    • Shimojo, M.1
  • 116
    • 34548291568 scopus 로고    scopus 로고
    • The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons
    • Sone M., Hayashi T., Tarui H., Agata K., Takeichi M., Nakagawa S. The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons. Journal of Cell Science 2007, 120:2498-2506.
    • (2007) Journal of Cell Science , vol.120 , pp. 2498-2506
    • Sone, M.1    Hayashi, T.2    Tarui, H.3    Agata, K.4    Takeichi, M.5    Nakagawa, S.6
  • 117
    • 36049020719 scopus 로고    scopus 로고
    • Noncoding RNAs: couplers of analog and digital information in nervous system function?
    • St L.G.R., Wahlestedt C. Noncoding RNAs: couplers of analog and digital information in nervous system function?. Trends in Neurosciences 2007, 30:612-621.
    • (2007) Trends in Neurosciences , vol.30 , pp. 612-621
    • St, L.G.R.1    Wahlestedt, C.2
  • 121
  • 124
    • 27944464131 scopus 로고    scopus 로고
    • Mapping of conserved RNA secondary structures predicts thousands of functional noncoding RNAs in the human genome
    • Washietl S., Hofacker I.L., Lukasser M., Huttenhofer A., Stadler P.F. Mapping of conserved RNA secondary structures predicts thousands of functional noncoding RNAs in the human genome. Nature Biotechnology 2005, 23:1383-1390.
    • (2005) Nature Biotechnology , vol.23 , pp. 1383-1390
    • Washietl, S.1    Hofacker, I.L.2    Lukasser, M.3    Huttenhofer, A.4    Stadler, P.F.5
  • 125
  • 126
    • 67649671961 scopus 로고    scopus 로고
    • Long noncoding RNAs: functional surprises from the RNA world
    • Wilusz J.E., Sunwoo H., Spector D.L. Long noncoding RNAs: functional surprises from the RNA world. Genes and Development 2009, 23:1494-1504.
    • (2009) Genes and Development , vol.23 , pp. 1494-1504
    • Wilusz, J.E.1    Sunwoo, H.2    Spector, D.L.3
  • 127
    • 79955788276 scopus 로고    scopus 로고
    • Naming 'junk': human non-protein coding RNA (ncRNA) gene nomenclature
    • Wright M.W., Bruford E.A. Naming 'junk': human non-protein coding RNA (ncRNA) gene nomenclature. Human Genomics 2011, 5:90-98.
    • (2011) Human Genomics , vol.5 , pp. 90-98
    • Wright, M.W.1    Bruford, E.A.2
  • 128
    • 84856999439 scopus 로고    scopus 로고
    • Stroke-induced microRNAs: the potential therapeutic role for stroke
    • (Review)
    • Wu P., Zuo X.L., Ji A.M. Stroke-induced microRNAs: the potential therapeutic role for stroke. Experimental and Therapeutics Medicine 2012, 3:571-576. (Review).
    • (2012) Experimental and Therapeutics Medicine , vol.3 , pp. 571-576
    • Wu, P.1    Zuo, X.L.2    Ji, A.M.3
  • 129
    • 0037016553 scopus 로고    scopus 로고
    • Role for brain-derived neurotrophic factor in learning and memory
    • Yamada K., Mizuno M., Nabeshima T. Role for brain-derived neurotrophic factor in learning and memory. Life Sciences 2002, 70:735-744.
    • (2002) Life Sciences , vol.70 , pp. 735-744
    • Yamada, K.1    Mizuno, M.2    Nabeshima, T.3
  • 131
    • 77957272505 scopus 로고    scopus 로고
    • Neurotrophins enhance CaMKII activity and rescue amyloid-beta-induced deficits in hippocampal synaptic plasticity
    • Zeng Y., Zhao D., Xie C.W. Neurotrophins enhance CaMKII activity and rescue amyloid-beta-induced deficits in hippocampal synaptic plasticity. Journal of Alzheimer's Disease 2010, 21:823-831.
    • (2010) Journal of Alzheimer's Disease , vol.21 , pp. 823-831
    • Zeng, Y.1    Zhao, D.2    Xie, C.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.