Regular Moderate or Intense Exercise Prevents Depression-Like Behavior without Change of Hippocampal Tryptophan Content in Chronically Tryptophan-Deficient and Stressed Mice

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Lee, Hosung ^a   Ohno, Makoto ^b   Ohta, Shigeo ^a   Mikami, Toshio ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b NIPPON SPORT SCIENCE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; NORADRENALIN; SEROTONIN; TRYPTOPHAN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANTIDEPRESSANT ACTIVITY; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC STRESS; CONTROLLED STUDY; DEPRESSION; DIET; EXERCISE; FORCED SWIMMING TEST; HIPPOCAMPUS; LONG TERM MEMORY; MALE; MOUSE; NONHUMAN; SHORT TERM MEMORY; TREADMILL EXERCISE; TRYPTOPHAN BRAIN LEVEL;

ANIMALS; AVOIDANCE LEARNING; BRAIN CHEMISTRY; CELL PROLIFERATION; DEPRESSION; HIPPOCAMPUS; MALE; MEMORY, LONG-TERM; MEMORY, SHORT-TERM; MICE; MICE, INBRED C57BL; NOREPINEPHRINE; PHYSICAL CONDITIONING, ANIMAL; RATS; SEROTONIN; STRESS, PSYCHOLOGICAL; TRYPTOPHAN;

ANIMALIA; MUS;

EID: 84879819257     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066996     Document Type: Article

References (45)

1. Krishnan V, Nestler EJ, (2008) The molecular neurobiology of depression. Nature 455: 894-902.
2. Jans LA, Riedel WJ, Markus CR, Blokland A, (2007) Serotonergic vulnerability and depression: assumptions, experimental evidence and implications. Mol Psychiatry 12: 522-543.
3. Cowen PJ, Parry-Billings M, Newsholme EA, (1989) Decreased plasma tryptophan levels in major depression. J Affect Disord 16: 27-31.
4. Birkmayer W, Riederer P, (1975) Biochemical post-mortem findings in depressed patients. J Neural Transm 37: 95-109.
5. Moja EA, Cipolla P, Castoldi D, Tofanetti O, (1989) Dose-response decrease in plasma tryptophan and in brain tryptophan and serotonin after tryptophan-free amino acid mixtures in rats. Life Sci 44: 971-976.
6. Stancampiano R, Melis F, Sarais L, Cocco S, Cugusi C, et al. (1997) Acute administration of a tryptophan-free amino acid mixture decreases 5-HT release in rat hippocampus in vivo. Am J Physiol 272: R991-994.
7. Blokland A, Lieben C, Deutz NE, (2002) Anxiogenic and depressive-like effects, but no cognitive deficits, after repeated moderate tryptophan depletion in the rat. J Psychopharmacol 16: 39-49.
8. Young SN, Smith SE, Pihl RO, Ervin FR, (1985) Tryptophan depletion causes a rapid lowering of mood in normal males. Psychopharmacology (Berl) 87: 173-177.
9. van Praag HM, (2004) Can stress cause depression? Prog Neuropsychopharmacol Biol Psychiatry 28: 891-907.
10. Gould E, Tanapat P, (1999) Stress and hippocampal neurogenesis. Biol Psychiatry 46: 1472-1479.
11. Magarinos AM, Verdugo JM, McEwen BS, (1997) Chronic stress alters synaptic terminal structure in hippocampus. Proc Natl Acad Sci U S A 94: 14002-14008.
12. McEwen BS, (2004) Protection and damage from acute and chronic stress: allostasis and allostatic overload and relevance to the pathophysiology of psychiatric disorders. Ann N Y Acad Sci 1032: 1-7.
13. Marazziti D, Consoli G, Picchetti M, Carlini M, Faravelli L, (2009) Cognitive impairment in major depression. Eur J Pharmacol 626: 83-86.
14. Lavie CJ, Milani RV, O'Keefe JH, Lavie TJ, (2011) Impact of exercise training on psychological risk factors. Prog Cardiovasc Dis 53: 464-470.
15. Carek PJ, Laibstain SE, Carek SM, (2011) Exercise for the treatment of depression and anxiety. Int J Psychiatry Med 41: 15-28.
16. Kiuchi T, Lee H, Mikami T, (2012) Regular exercise cures depression-like behavior via VEGF-Flk-1 signaling in chronically stressed mice. Neuroscience 207: 208-217.
17. Nakajima S, Ohsawa I, Nagata K, Ohta S, Ohno M, et al. (2009) Oral supplementation with melon superoxide dismutase extract promotes antioxidant defences in the brain and prevents stress-induced impairment of spatial memory. Behav Brain Res 200: 15-21.
18. Banasr M, Valentine GW, Li XY, Gourley SL, Taylor JR, et al. (2007) Chronic unpredictable stress decreases cell proliferation in the cerebral cortex of the adult rat. Biol Psychiatry 62: 496-504.
19. Porsolt RD, Le Pichon M, Jalfre M, (1977) Depression: a new animal model sensitive to antidepressant treatments. Nature 266: 730-732.
20. Sakata K, Jin L, Jha S, (2010) Lack of promoter IV-driven BDNF transcription results in depression-like behavior. Genes Brain Behav 9: 712-721.
21. O'Riordan KJ, Huang IC, Pizzi M, Spano P, Boroni F, et al. (2006) Regulation of nuclear factor kappaB in the hippocampus by group I metabotropic glutamate receptors. J Neurosci 26: 4870-4879.
22. De Rosa R, Garcia AA, Braschi C, Capsoni S, Maffei L, et al. (2005) Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice. Proc Natl Acad Sci U S A 102: 3811-3816.
23. Wang H, Ferguson GD, Pineda VV, Cundiff PE, Storm DR, (2004) Overexpression of type-1 adenylyl cyclase in mouse forebrain enhances recognition memory and LTP. Nat Neurosci 7: 635-642.
24. Trejo JL, Carro E, Torres-Aleman I, (2001) Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus. J Neurosci 21: 1628-1634.
25. Zhang H, Joseph J, Crow J, Kalyanaraman B, (2004) Mass spectral evidence for carbonate-anion-radical-induced posttranslational modification of tryptophan to kynurenine in human Cu, Zn superoxide dismutase. Free Radic Biol Med 37: 2018-2026.
26. Kee N, Sivalingam S, Boonstra R, Wojtowicz JM, (2002) The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesis. J Neurosci Methods 115: 97-105.
27. Shidara Y, Yamagata K, Kanamori T, Nakano K, Kwong JQ, et al. (2005) Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis. Cancer Res 65: 1655-1663.
28. Malberg JE, Eisch AJ, Nestler EJ, Duman RS, (2000) Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 20: 9104-9110.
29. Marcussen AB, Flagstad P, Kristjansen PE, Johansen FF, Englund U, (2008) Increase in neurogenesis and behavioural benefit after chronic fluoxetine treatment in Wistar rats. Acta Neurol Scand 117: 94-100.
30. Paizanis E, Renoir T, Lelievre V, Saurini F, Melfort M, et al. (2009) Behavioural and neuroplastic effects of the new-generation antidepressant agomelatine compared to fluoxetine in glucocorticoid receptor-impaired mice. Int J Neuropsychopharmacol: 1-16.
31. Deltheil T, Guiard BP, Cerdan J, David DJ, Tanaka KF, et al. (2008) Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice. Neuropharmacology 55: 1006-1014.
32. Langfort J, Baranczuk E, Pawlak D, Chalimoniuk M, Lukacova N, et al. (2006) The effect of endurance training on regional serotonin metabolism in the brain during early stage of detraining period in the female rat. Cell Mol Neurobiol 26: 1327-1342.
33. Hasegawa H, Piacentini MF, Sarre S, Michotte Y, Ishiwata T, et al. (2008) Influence of brain catecholamines on the development of fatigue in exercising rats in the heat. J Physiol 586: 141-149.
34. Hasegawa H, Takatsu S, Ishiwata T, Tanaka H, Sarre S, et al. (2011) Continuous monitoring of hypothalamic neurotransmitters and thermoregulatory responses in exercising rats. J Neurosci Methods 202: 119-123.
35. Takatsu S, Ishiwata T, Meeusen R, Sarre S, Hasegawa H, (2010) Serotonin release in the preoptic area and anterior hypothalamus is not involved in thermoregulation during low-intensity exercise in a warm environment. Neurosci Lett 482: 7-11.
36. Counts SE, Mufson EJ, (2010) Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity. J Neurochem 113: 649-660.
37. Patel NJ, Chen MJ, Russo-Neustadt AA, (2010) Norepinephrine and nitric oxide promote cell survival signaling in hippocampal neurons. Eur J Pharmacol 633: 1-9.
38. Hunsberger JG, Newton SS, Bennett AH, Duman CH, Russell DS, et al. (2007) Antidepressant actions of the exercise-regulated gene VGF. Nat Med 13: 1476-1482.
39. Li S, Wang C, Wang W, Dong H, Hou P, et al. (2008) Chronic mild stress impairs cognition in mice: from brain homeostasis to behavior. Life Sci 82: 934-942.
40. Mineur YS, Belzung C, Crusio WE, (2007) Functional implications of decreases in neurogenesis following chronic mild stress in mice. Neuroscience 150: 251-259.
41. Fuss J, Ben Abdallah NM, Vogt MA, Touma C, Pacifici PG, et al. (2009) Voluntary exercise induces anxiety-like behavior in adult C57BL/6J mice correlating with hippocampal neurogenesis. Hippocampus.
42. Olivier JD, Jans LA, Blokland A, Broers NJ, Homberg JR, et al. (2009) Serotonin transporter deficiency in rats contributes to impaired object memory. Genes Brain Behav 8: 829-834.
43. Nakajima S, Ohsawa I, Ohta S, Ohno M, Mikami T, (2010) Regular voluntary exercise cures stress-induced impairment of cognitive function and cell proliferation accompanied by increases in cerebral IGF-1 and GST activity in mice. Behav Brain Res 211: 178-184.
44. Chen G, Zou X, Watanabe H, van Deursen JM, Shen J, (2010) CREB binding protein is required for both short-term and long-term memory formation. J Neurosci 30: 13066-13077.
45. Bredy TW, Wu H, Crego C, Zellhoefer J, Sun YE, et al. (2007) Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear. Learn Mem 14: 268-276.