Kcentra: A 4-factor prothrombin complex concentrate for reversal of warfarin anticoagulation

Medical Letter on Drugs and Therapeutics

Volumn 55, Issue 1420, 2013, Pages 53-54

[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

APIXABAN; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 9; CALCIUM ION; DABIGATRAN; DABIGATRAN ETEXILATE; FRESH FROZEN PLASMA; KCENTRA; PROTHROMBIN; PROTHROMBIN COMPLEX; RIVAROXABAN; UNCLASSIFIED DRUG; VITAMIN K GROUP; WARFARIN;

ANTICOAGULATION; BLEEDING; DRUG COST; DRUG SAFETY; HUMAN; LETTER; THROMBOEMBOLISM; TREATMENT OUTCOME;

BLOOD COAGULATION DISORDERS; BLOOD COAGULATION FACTORS; DRUG APPROVAL; HUMANS; THROMBOEMBOLISM; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION; WARFARIN;

EID: 84879754339     PISSN: 0025732X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (7)

1. JS Kalus et al. Pharmacologic interventions for reversing the effects of oral anticoagulants. Am J Health Syst Pharm 2013; 70 [10 Suppl 1]: S12.
2. Prothrombin complex concentrates to reverse warfarin-related bleeding. Med Lett Drugs Ther 2011; 53:78.
3. SA Voils and B Baird. Systematic review: 3-factor versus 4-factor prothrombin complex concentrate for warfarin reversal: does it matter? Thromb Res 2012; 130:833.
4. A Holbrook et al. Evidence-based management of anticoagulant therapy: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 2012; 141(2 Suppl):e152S.
5. I Pabinger et al. Prothrombin complex concentrate (Beriplex P/N) for emergency anticoagulation reversal: a prospective multinational clinical trial. J Thromb Haemost 2008; 6:622.
6. AE Patanwala et al. Prothrombin complex concentrate for critical bleeding. Ann Pharmacother 2011; 45:990.
7. M Zareh et al. Reversal of warfarin-induced hemorrhage in the emergency department. West J Emerg Med 2011; 12:386.