Synthesis, cytotoxic, and DNA binding studies of novel fluorinated condensed pyrano pyrazoles

Medicinal Chemistry Research

Volumn 22, Issue 5, 2013, Pages 2446-2454

  Bhavanarushi, S ^a   Kanakaiah, V ^a   Yakaiah, E ^a   Saddanapu, V ^a   Addlagatta, A ^a   Rani, J Vatsala ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

DBU; Electrochemical; HeLa cells; Intercalation; Knoevenagel condensation; Pyrano 2,3 c pyrazole

Indexed keywords

6 AMINO 1 (3 CHLOROPHENYL) 4 (4 METHOXYPHENYL) 3 (TRIFLUOROMETHYL) 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CAROBONITRILE; 6 AMINO 1 (3 CHLOROPHENYL) 4 (4 NITROPHENYL) 3 (TRIFLUOROMETHYL) 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CAROBONITRILE; 6 AMINO 1 (3 CHLOROPHENYL) 4 (FURAN 2 YL) 3 (TRIFLUOROMETHYL) 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CAROBONITRILE; 6 AMINO 1 (3 CHLOROPHENYL) 4 PHENYL 3 (TRIFLUOROMETHYL) 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CAROBONITRILE; 6 AMINO 1 (4 FLUOROPHENYL) 4 (4 METHOXYPHENYL) 3 (TRIFLUOROMETHYL) 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CAROBONITRILE; 6 AMINO 1 (4 FLUOROPHENYL) 4 (4 NITROPHENYL) 3 (TRIFLUOROMETHYL) 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CAROBONITRILE; 6 AMINO 1 (4 FLUOROPHENYL) 4 (THIOPHEN 2 YL) 3 (TRIFLUOROMETHYL) 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CAROBONITRILE; 6 AMINO 1 (4 FLUOROPHENYL) 4 P TOLYL 3 (TRIFLUOROMETHYL) 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CAROBONITRILE; 6 AMINO 1 (4 FLUOROPHENYL) 4 PHENYL 3 (TRIFLUOROMETHYL) 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CAROBONITRILE; 6 AMINO 1 PHENYL 4 (THIOPHEN 2 YL) 3 (TRIFLUOROMETHYL) 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CAROBONITRILE; 6 AMINO 4 (3 METHOXYPHENYL) 1 PHENYL 3 (TRIFLUOROMETHYL) 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CAROBONITRILE; 6 AMINO 4 (4 FLUOROPHENYL) 1 PHENYL 3 (TRIFLUOROMETHYL) 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CARBONITRILE; 6 AMINO 4 (4 NITROPHENYL) 1 PHENYL 3 (TRIFLUOROMETHYL) 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CAROBONITRILE; 6 AMINO 4 (FURAN 2 YL) 1 PHENYL 3 (TRIFLUOROMETHYL) 1,4 DIHYDROPYRANO[2,3 C]PYRAZOLE 5 CAROBONITRILE; ANTINEOPLASTIC AGENT; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CYCLIC POTENTIOMETRY; DNA BINDING; DRUG SYNTHESIS; ELECTROCHEMISTRY; HUMAN; HUMAN CELL; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 84879690694     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0239-z     Document Type: Article

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