Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation

EMBO Reports

Volumn 14, Issue 7, 2013, Pages 629-637

  Grabole, Nils ^a   Tischler, Julia ^a   Hackett, Jamie A ^a   Kim, Shinseog ^a   Tang, Fuchou ^a,b   Leitch, Harry G ^a   Magnúsdóttir, Erna ^a   Surani, M Azim ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b PEKING UNIVERSITY   (China)

Author keywords

DNA methylation; FGF signalling; pluripotency; Prdm14; primordial germ cells

Indexed keywords

FIBROBLAST GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN PRDM14; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL FATE; DNA METHYLATION; EMBRYO; EMBRYONIC STEM CELL; GENE EXPRESSION; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIMORDIAL GERM CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; DNA METHYLATION; EMBRYONIC STEM CELLS; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM CELLS; GERM LAYERS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASES; PLURIPOTENT STEM CELLS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

MUS;

EID: 84879690355     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2013.67     Document Type: Article

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