Cell culture using centrifugal microfluidic platform with demonstration on Pichia pastoris

Biomedical Microdevices

Volumn 15, Issue 2, 2013, Pages 321-337

  Ren, Yong ^a   Chow, Larry Ming Cheung ^a   Leung, Wallace Woon Fong ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

Cell culture; Centrifugal microfluidics; Lab on a chip; Mixing; Vortical flow

Indexed keywords

ACCELERATION/DECELERATION; CELL CONCENTRATIONS; CENTRIFUGAL MICROFLUIDIC PLATFORM; CENTRIFUGAL MICROFLUIDICS; CORIOLIS ACCELERATION; NUMERICAL DIFFUSION; ROTATION DIRECTIONS; VORTICAL FLOWS;

ACCELERATION CONTROL; CELL GROWTH; CENTRIFUGATION; COLOR; GROWTH KINETICS; LAB-ON-A-CHIP; MICROFLUIDICS; MIXING; VORTEX FLOW; YEAST;

CELL CULTURE;

ARTICLE; CELL CULTURE; CELL CULTURE EQUIPMENT; CELL GROWTH; CENTRIFUGAL MICROFLUIDICS; CENTRIFUGATION; CONTROLLED STUDY; CULTURE MEDIUM; CULTURE TECHNIQUE; FUNGAL CELL; INTERMETHOD COMPARISON; MICROFLUIDICS; NONHUMAN; OPTICAL DENSITY; PICHIA PASTORIS; PRIORITY JOURNAL;

BATCH CELL CULTURE TECHNIQUES; BIOREACTORS; CELL PROLIFERATION; CELL SURVIVAL; CENTRIFUGATION; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; MICROFLUIDIC ANALYTICAL TECHNIQUES; PICHIA;

PICHIA PASTORIS;

EID: 84879686836     PISSN: 13872176     EISSN: 15728781     Source Type: Journal    
DOI: 10.1007/s10544-012-9735-7     Document Type: Article

References (42)

1. A. Bhagat, H. Bow, H. Hou, S. Tan, J. Han, C. Lim, Microfluidics for cell separation. Med. Biol. Eng. Comput. 48(10), 999-1014 (2010)
2. M.R. Bringer, C.J. Gerdts, H. Song, J.D. Tice, R.F. Ismagilov, Microfluidic systems for chemical kinetics that rely on chaotic mixing in droplets. Philos. Trans. R. Soc. London, Ser. A 362, 1087-1104 (2004)
3. D. Chakraborty, M. Madou, S. Chakraborty, Anomalous mixing behavior in rotationally actuated microfluidic devices. Lab Chip 11, 2823-2826 (2011)
4. W.J. Chang, D. Akin, M. Sedlak, M.R. Ladisch, R. Bashir, Poly(dimethylsiloxane) (PDMS) and silicon hybrid biochip for bacterial culture. Biomed. Microdev. 5, 281-290 (2003)
5. J.M. Cregg, I. Tolstorukov, A. Kusari, J. Sunga, K. Madden, T. Chappell, Expression in the yeast Pichia pastoris. Meth. Enzymol. 463, 169-189 (2009)
6. J. Ducrée, S. Haeberle, S. Lutz, S. Pausch, F. Stetten, R. Zengerle, The centrifugal microfluidic bio-disk platform. J. Micromech. Microeng. 17, 103-115 (2007)
7. K.N. Faber, W. Harder, M. Veenhuis, Review: methylotropic yeasts as factories for the production of foreign proteins. Yeast 11, 1331-1344 (1995)
8. D. Gao, H. Liu, Y. Jiang, J. Lin, Recent developments in microfluidic devices for in vitro cell culture for cell-biology research. Trac- Trend. Anal. Chem. 35, 150-164 (2012)
9. R. Gómez, R. Bashir, A.K. Bhunia, Microscale electronic detection of bacterial metabolism. Sensors Actuators B 86, 198-208 (2002)
10. R. Gorkin, J. Park, J. Siegrist, M. Amasia, B.S. Lee, J.M. Park, J. Kim, H. Kim, M. Madou, Y.K. Cho, Centrifugal microfluidics for biomedical applications. Lab Chip 10(14), 1758-1773 (2010)
11. M. Grumann, A. Geipel, L. Riegger, R. Zengerle, J. Ducrée, Batch-mode mixing on centrifugal microfluidic platforms. Lab Chip 5, 560-565 (2005)
12. C.W. Huang, G.B. Lee, A microfluidic system for automatic cell culture. J. Micromech. Microeng. 17, 1266-1274 (2007)
13. M. Huang, S. Fan, W. Xing, C. Liu, Microfluidic cell culture system studies and computational fluid dynamics. Math. Comput. Model. 52(11-12), 2036-2042 (2010)
14. P.J. Hung, P.J. Lee, P. Sabounchi, R. Lin, L.P. Lee, Continuous perfusion microfluidic cell culture array for high-throughput cell-based assays. Biotechnol. Bioeng. 89(1), 1-8 (2005)
15. N.K. Inamdar, J.T. Borenstein, Microfluidic cell culture models for tissue engineering. Curr. Opin. Biotechnol. 22(5), 681-689 (2011)
16. N. Kim, C.M. Dempsey, J.V. Zoval, J. Sze, M.J. Madou, Automated microfluidic compact disc (CD) cultivation system of Caenorhabditis elegans. Sensors Actuators B 122, 511-518 (2007)
17. T.J. Kim, S.J. Kim, H.I. Jung, Physical stimulation of mammalian cells using micro-bead impact within a microfluidic environment to enhance growth rate. Microfluid Nanofluid 6, 131-138 (2009)
18. K. Kojima, H. Moriguchi, A. Hattori, T. Kaneko, K. Yasuda, Two-dimensional network formation of cardiac myocytes in agar microculture chip with 1480 nm infrared laser photo-thermal etching. Lab Chip 3, 292-296 (2003)
19. C.Y. Lee, G.B. Lee, J.L. Lin, F.C. Huang, L.C. Sheng, Integrated microfluidic systems for cell lysis, mixing/pumping and DNA amplification. J. Micromech. Microeng. 15(6), 1215 (2005)
20. K.F. Lei, M.H. Wu, P.Y. Liao, Y.M. Chen, T.M. Pan, Development of a micro-scale perfusion 3-D cell culture biochip with an incorporated electrical impedance measurement scheme for the quantification of cell number in a 3-D cell culture construct. Microfluid Nanofluid 12, 117-125 (2012)
21. M. Madou, J. Zoval, G. Jia, H. Kido, J. Kim, N. Kim, Lab on a CD. Annu. Rev. Biomed. Eng. 8(1), 601-628 (2006)
22. D. Mark, S. Haeberle, G. Roth, F. von Stetten, R. Zengerle, Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications. Chem. Soc. Rev. 39(3), 1153 (2010)
23. N.T. Nguyen, S.T. Wereley, Fundamentals and applications of microfluidics, 2nd edn. (Artech House, Boston, 2006)
24. J. Nielsen, J. Villadsen, Bioreaction engineering principles (Plenum Press, New York, 1994)
25. M.J. Powers, K. Domansky, M.R. Kaazempur-Mofrad, A. Kalezi, A. Capitano, A. Upadhyaya, P. Kurzawski, K.E. Wack, D.B. Stolz, R. Kamm, L.G. Griffith, A microfabricated array bioreactor for perfused 3-D liver culture. Biotechnol. Bioeng. 78, 257-269 (2002)
26. Y. Ren, W.W.F. Leung, Numerical and experimental investigation on flow and mixing in batch-mode centrifugal microfluidics. Int. J. Heat Mass Transfer (in press) (2012)
27. G. Roman, Y. Chen, P. Viberg, A. Culbertson, C. Culbertson, Single-cell manipulation and analysis using microfluidic devices. Anal. Bioanal. Chem. 387(1), 9-12 (2007)
28. A. Sin, K.C. Chin, M.F. Jamil, Y. Kostov, G. Rao, M.L. Shuler, The design and fabrication of three-chamber microscale cell culture analog devices with integrated dissolved oxygen sensors. Biotechnol. 20, 338-345 (2004)
29. M. Stangegaard, S. Petronis, A.M. Jørgensen, C.B.V. Christensenc, M. Dufva, A biocompatible micro cell culture chamber (μCCC) for the culturing and on-line monitoring of eukaryote cells. Lab Chip 6, 1045-1051 (2006)
30. 2 incubation for pocket-sized microfluidic cell culture. Microfluid Nanofluid 12, 907-915 (2012)
31. T. Thorsen, S. Maerkl, S. Quake, Microfluidic large scale integration. Science 298, 580-584 (2002)
32. Y.C. Toh, J. Voldman, Fluid shear stress primes mouse embryonic stem cells for differentiation in a self-renewing environment via heparan sulfate proteoglycans transduction. FASEB J. 25(4), 1208-1217 (2011)
33. E. Verpoorte, N.F. De Rooij, Microfluidics meets MEMS. Proc. IEEE 91(6), 930-953 (2003)
34. H.Y. Wang, N. Bao, C. Lu, A microfluidic cell array with individually addressable culture chambers. Biosens. Bioelectron. 24, 613-617 (2008)
35. D.B. Weibel, P.G. Garstecki, G.M. Whitesides, Combining microscience and neurobiology. Curr. Opin. Neurobiol. 15, 560-567 (2005)
36. G.M. Whitesides, The origins and the future of microfluidics. Nature 442(7101), 368-373 (2006)
37. M.H. Wu, J.L. Lin, J. Wang, Z. Cui, Z. Cui, Development of high throughput optical sensor array for on-line pH monitoring in micro-scale cell culture environment. Biomed. Microdevices 11, 265-273 (2009)
38. M.H. Wu, S.B. Huang, G.B. Lee, Microfluidic cell culture systems for drug research. Lab Chip 10, 939-956 (2010)
39. C.H. Yeh, P.W. Lin, Y.C. Lin, Chitosan microfiber fabrication using a microfluidic chip and its application to cell cultures. Microfluid Nanofluid 8, 115-121 (2010)
40. J.H. Yeon, J.K. Park, Microfluidic cell culture systems for cellular analysis. Biochip J. 1(1), 17-27 (2007)
41. C. Yi, C.W. Li, S. Ji, M. Yang, Microfluidics technology for manipulation and analysis of biological cells. Anal. Chim. Acta 560, 1-23 (2006)
42. S.K. Yoo, J.H. Lee, S.S. Yun, M.B. Gu, J.H. Lee, Fabrication of a bio-MEMS based cell-chip for toxicity monitoring. Biosens. Bioelectron. 22, 1586-1592 (2007)