Development of stability indicating method for validation of Losartan potassium and hydrochlorothiazide drugs in solid dosage form by RP-HPLC

International Journal of Pharma and Bio Sciences

Volumn 4, Issue 1, 2013, Pages 621-638

  Anis, Shaikh ^a  

^a VIKRAM UNIVERSITY   (India)

Author keywords

Antihypertensive; Chromatograms; Quantitated; Resolution; Theoretical plates

Indexed keywords

HYDROCHLOROTHIAZIDE; LOSARTAN POTASSIUM;

ACCURACY; ARTICLE; CHEMICAL PARAMETERS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DETERMINATION; DRUG EFFICACY; DRUG POTENCY; DRUG QUALITY; DRUG SAFETY; DRUG SPECIFICITY; DRUG STABILITY; DRUG STRUCTURE; FLOW RATE; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LINEARITY; PROCESS DEVELOPMENT; RANGE; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ROBUSTNESS; VALIDATION PROCESS;

EID: 84879668705     PISSN: None     EISSN: 09756299     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. BN Suhagia, RR Shah, DM Patel, "Development of a RP-HPLC method for evaluating losartan Potassium and Hydrochlorothiazide Tablets" Indian journal of pharmaceutical sciences, vol- 67, year-2005, issue1, Page 37-42.
2. Deanne L. Hertzog, Jennifer Finnegan. McCafferty, Xueguang Fang, R. Jeffrey Tyrrell, and Robert A. Reed, "Development and validation of a stability-indicating HPLC method for the simultaneous determination of Losartan potassium, hydrochlorothiazide, and their degradation products" Journal of Pharmaceutical and Biomedical Analysis, Volume 30, Issue 3, 15 October 2002, Pages 747-760.
3. P C kamboj, Handbook of pharmaceutical analysis, Volume 1, 212-213.
4. Dr. A.V. kasture, K.R. mahadik, S.G. wadodkar, H.N. More, Pharmaceutical analysis, Volume II, Nirali prakashan, 99-101.
5. K.D. Tripathi. Introduction to pharmacology, fifth edition, 2007, 315-316.
6. ICH guidelines, Validation of analytical procedures, Q2 (R1).
7. www.wikipedia.org/losartan potassium.(accessed on 12-8-2008)
8. www.wikipedia.org/Hydrochlorothiazide. .(accessed on 12-8-2008)
9. www.rxlist.com/Losartan Potassium. .(accessed on 15-9-2008)
10. www.rxlist.com/Hydrochlorothiazide.(acc essed on 15-9-2008)