-
1
-
-
34047207229
-
Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: A pooled subgroup analysis of data from two randomised trials
-
17416261 10.1016/S0140-6736(07)60497-8 1:CAS:528:DC%2BD2sXjvFejtro%3D
-
Clotet B, Bellos N, Molina JM, et al. Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: a pooled subgroup analysis of data from two randomised trials. Lancet. 2007;369(9568):1169-78.
-
(2007)
Lancet
, vol.369
, Issue.9568
, pp. 1169-1178
-
-
Clotet, B.1
Bellos, N.2
Molina, J.M.3
-
2
-
-
69449092725
-
Once-daily darunavir/ritonavir vs. lopinavir/ritonavir in treatment-naive, HIV-1-infected patients: 96-week analysis
-
19487905 10.1097/QAD.0b013e32832d7350 1:CAS:528:DC%2BD1MXpvV2gtbg%3D
-
Mills AM, Nelson M, Jayaweera D, et al. Once-daily darunavir/ritonavir vs. lopinavir/ritonavir in treatment-naive, HIV-1-infected patients: 96-week analysis. AIDS. 2009;23(13):1679-88.
-
(2009)
AIDS
, vol.23
, Issue.13
, pp. 1679-1688
-
-
Mills, A.M.1
Nelson, M.2
Jayaweera, D.3
-
3
-
-
34548300159
-
Clinical pharmacokinetics of darunavir
-
17713972 10.2165/00003088-200746090-00002 1:CAS:528:DC%2BD2sXhtFyqt77E
-
Rittweger M, Arastéh K. Clinical pharmacokinetics of darunavir. Clin Pharmacokinet. 2007;46(9):739-56.
-
(2007)
Clin Pharmacokinet
, vol.46
, Issue.9
, pp. 739-756
-
-
Rittweger, M.1
Arastéh, K.2
-
4
-
-
2042472820
-
Pharmacokinetic enhancement of protease inhibitor therapy
-
15080763 10.2165/00003088-200443050-00003 1:CAS:528:DC%2BD2cXktFOqtbs%3D
-
King JR, Wynn H, Brundage R, et al. Pharmacokinetic enhancement of protease inhibitor therapy. Clin Pharmacokinet. 2004;43(5):291-310.
-
(2004)
Clin Pharmacokinet
, vol.43
, Issue.5
, pp. 291-310
-
-
King, J.R.1
Wynn, H.2
Brundage, R.3
-
5
-
-
27744594298
-
Interindividual variability of once-daily ritonavir boosted saquinavir pharmacokinetics in Thai and UK patients
-
16204340 10.1093/jac/dki354 1:CAS:528:DC%2BD2MXhtFCjtLfI
-
Autar RS, Boffito M, Hassink E, et al. Interindividual variability of once-daily ritonavir boosted saquinavir pharmacokinetics in Thai and UK patients. J Antimicrob Chemother. 2005;56(5):908-13.
-
(2005)
J Antimicrob Chemother
, vol.56
, Issue.5
, pp. 908-913
-
-
Autar, R.S.1
Boffito, M.2
Hassink, E.3
-
6
-
-
62649107112
-
A low dose of ritonavir-boosted atazanavir provides adequate pharmacokinetic parameters in HIV-1-infected Thai adults
-
19118378 10.1038/clpt.2008.244 1:CAS:528:DC%2BD1MXjtlSmu7o%3D
-
Avihingsanon A, van der Lugt J, Kerr SJ, et al. A low dose of ritonavir-boosted atazanavir provides adequate pharmacokinetic parameters in HIV-1-infected Thai adults. Clin Pharmacol Ther. 2009;85(4):402-8.
-
(2009)
Clin Pharmacol Ther
, vol.85
, Issue.4
, pp. 402-408
-
-
Avihingsanon, A.1
Van Der Lugt, J.2
Kerr, S.J.3
-
7
-
-
84865709630
-
Estimation of the effect of SLCO1B1 polymorphisms on lopinavir plasma concentration in HIV-infected adults
-
22477766 10.3851/IMP2095 1:CAS:528:DC%2BC38XhtlGgtbnP
-
Schipani A, Egan D, Dickinson L, et al. Estimation of the effect of SLCO1B1 polymorphisms on lopinavir plasma concentration in HIV-infected adults. Antivir Ther. 2012;17(5):861-8.
-
(2012)
Antivir Ther
, vol.17
, Issue.5
, pp. 861-868
-
-
Schipani, A.1
Egan, D.2
Dickinson, L.3
-
8
-
-
77950787858
-
ADME pharmacogenetics: Investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir
-
20139798 1:CAS:528:DC%2BC3cXjs1ajt7c%3D
-
Lubomirov R, di Iulio J, Fayet A, et al. ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir. Pharmacogenet Genomics. 2010;20(4):217-30.
-
(2010)
Pharmacogenet Genomics
, vol.20
, Issue.4
, pp. 217-230
-
-
Lubomirov, R.1
Di Iulio, J.2
Fayet, A.3
-
9
-
-
78649673343
-
Population pharmacokinetic modeling of the association between 63396C→T pregnane X receptor polymorphism and unboosted atazanavir clearance
-
20921307 10.1128/AAC.00781-10 1:CAS:528:DC%2BC3cXhsF2msr7M
-
Schipani A, Siccardi M, D'Avolio A, et al. Population pharmacokinetic modeling of the association between 63396C→T pregnane X receptor polymorphism and unboosted atazanavir clearance. Antimicrob Agents Chemother. 2010;54(12):5242-50.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, Issue.12
, pp. 5242-5250
-
-
Schipani, A.1
Siccardi, M.2
D'Avolio, A.3
-
10
-
-
35448967118
-
Inhibition of P-glycoprotein and multidrug resistance-associated proteins modulates the intracellular concentration of lopinavir in cultured CD4 T cells and primary human lymphocytes
-
17890284 10.1093/jac/dkm353 1:CAS:528:DC%2BD2sXht1ShtrbM
-
Janneh O, Jones E, Chandler B, et al. Inhibition of P-glycoprotein and multidrug resistance-associated proteins modulates the intracellular concentration of lopinavir in cultured CD4 T cells and primary human lymphocytes. J Antimicrob Chemother. 2007;60(5):987-93.
-
(2007)
J Antimicrob Chemother
, vol.60
, Issue.5
, pp. 987-993
-
-
Janneh, O.1
Jones, E.2
Chandler, B.3
-
11
-
-
27944460405
-
Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP
-
16284458 10.1097/01.aids.0000194793.36175.40 1:CAS:528:DC%2BD2MXht1Sgt7fP
-
Janneh O, Owen A, Chandler B, et al. Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP. AIDS. 2005;19(18):2097-102.
-
(2005)
AIDS
, vol.19
, Issue.18
, pp. 2097-2102
-
-
Janneh, O.1
Owen, A.2
Chandler, B.3
-
12
-
-
2442638219
-
Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of Saquinavir in Hep G2 cells
-
15832500 10.1021/mp0340136 1:CAS:528:DC%2BD3sXps1Wnsr4%3D
-
Su Y, Zhang X, Sinko PJ. Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of Saquinavir in Hep G2 cells. Mol Pharm. 2004;1(1):49-56.
-
(2004)
Mol Pharm
, vol.1
, Issue.1
, pp. 49-56
-
-
Su, Y.1
Zhang, X.2
Sinko, P.J.3
-
13
-
-
75649091119
-
HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms
-
20051929 10.1097/FPC.0b013e328335b02d 1:CAS:528:DC%2BC3cXnvFyrsQ%3D%3D
-
Hartkoorn RC, Kwan WS, Shallcross V, et al. HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms. Pharmacogenet Genomics. 2010;20(2):112-20.
-
(2010)
Pharmacogenet Genomics
, vol.20
, Issue.2
, pp. 112-120
-
-
Hartkoorn, R.C.1
Kwan, W.S.2
Shallcross, V.3
-
14
-
-
0037339318
-
Evaluation of antiretroviral drug measurements by an interlaboratory quality control program
-
12626888 10.1097/00126334-200303010-00007
-
Droste JA, Aarnoutse RE, Koopmans PP, et al. Evaluation of antiretroviral drug measurements by an interlaboratory quality control program. J Acquir Immune Defic Syndr. 2003;32(3):287-91.
-
(2003)
J Acquir Immune Defic Syndr
, vol.32
, Issue.3
, pp. 287-291
-
-
Droste, J.A.1
Aarnoutse, R.E.2
Koopmans, P.P.3
-
16
-
-
0031763639
-
Assumption testing in population pharmacokinetic models: Illustrated with an analysis of moxonidine data from congestive heart failure patients
-
9795882 10.1023/A:1020561807903 1:CAS:528:DyaK1cXntVKqurY%3D
-
Karlsson MO, Jonsson EN, Wiltse CG, et al. Assumption testing in population pharmacokinetic models: illustrated with an analysis of moxonidine data from congestive heart failure patients. J Pharmacokinet Biopharm. 1998;26(2):207-46.
-
(1998)
J Pharmacokinet Biopharm
, vol.26
, Issue.2
, pp. 207-246
-
-
Karlsson, M.O.1
Jonsson, E.N.2
Wiltse, C.G.3
-
17
-
-
0002322365
-
Xpose: An S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM
-
10195646 10.1016/S0169-2607(98)00067-4 1:STN:280:DyaK1M3htVShsw%3D%3D
-
Jonsson EN, Karlsson MO. Xpose: an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM. Comput Methods Programs Biomed. 1999;58:51-64.
-
(1999)
Comput Methods Programs Biomed
, vol.58
, pp. 51-64
-
-
Jonsson, E.N.1
Karlsson, M.O.2
-
18
-
-
51649107032
-
Simultaneous population pharmacokinetic model for lopinavir and ritonavir in HIV-infected adults
-
18783298 10.2165/00003088-200847100-00005
-
Moltó J, Barbanoj MJ, Miranda C, et al. Simultaneous population pharmacokinetic model for lopinavir and ritonavir in HIV-infected adults. Clin Pharmacokinet. 2008;47(10):681-92.
-
(2008)
Clin Pharmacokinet
, vol.47
, Issue.10
, pp. 681-692
-
-
Moltó, J.1
Barbanoj, M.J.2
Miranda, C.3
-
19
-
-
0036173443
-
Pharmacokinetic modeling and simulations of interaction of amprenavir and ritonavir
-
11850257 10.1128/AAC.46.3.746-754.2002 1:CAS:528:DC%2BD38XhsVKhtb0%3D
-
Sale M, Sadler BM, Stein DS. Pharmacokinetic modeling and simulations of interaction of amprenavir and ritonavir. Antimicrob Agents Chemother. 2002;46(3):746-54.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, Issue.3
, pp. 746-754
-
-
Sale, M.1
Sadler, B.M.2
Stein, D.S.3
-
20
-
-
1842833729
-
Model-based analysis of the pharmacokinetic interactions between ritonavir, nelfinavir, and saquinavir after simultaneous and staggered oral administration
-
12433819 10.1124/dmd.30.12.1455 1:CAS:528:DC%2BD38XptVyisb4%3D
-
Lu JF, Blaschke TF, Flexner C, et al. Model-based analysis of the pharmacokinetic interactions between ritonavir, nelfinavir, and saquinavir after simultaneous and staggered oral administration. Drug Metab Dispos. 2002;30(12):1455-61.
-
(2002)
Drug Metab Dispos
, vol.30
, Issue.12
, pp. 1455-1461
-
-
Lu, J.F.1
Blaschke, T.F.2
Flexner, C.3
-
21
-
-
13444270590
-
Development and validation of a population pharmacokinetic model for ritonavir used as a booster or as an antiviral agent in HIV-1-infected patients
-
15676039 10.1111/j.1365-2125.2004.02241.x 1:CAS:528:DC%2BD2MXitFOgsLs%3D
-
Kappelhoff BS, Huitema AD, Crommentuyn KM, et al. Development and validation of a population pharmacokinetic model for ritonavir used as a booster or as an antiviral agent in HIV-1-infected patients. Br J Clin Pharmacol. 2005;59(2):174-82.
-
(2005)
Br J Clin Pharmacol
, vol.59
, Issue.2
, pp. 174-182
-
-
Kappelhoff, B.S.1
Huitema, A.D.2
Crommentuyn, K.M.3
-
22
-
-
84937835983
-
Development and application of a population pharmacokinetic model of TMC114 in healthy volunteers and HIV-1 infected subjects alter administration of TMC114 in combination with low dose ritonavir [abstract no. 964]
-
2006 June 14-16; Bruges, Belgium
-
Vis P, Sekar V, van Schaick E, et al. Development and application of a population pharmacokinetic model of TMC114 in healthy volunteers and HIV-1 infected subjects alter administration of TMC114 in combination with low dose ritonavir [abstract no. 964] 15th meeting of the Population Approach Group in Europe. 2006 June 14-16; Bruges, Belgium.
-
15th Meeting of the Population Approach Group in Europe
-
-
Vis, P.1
Sekar, V.2
Van Schaick, E.3
-
23
-
-
33847069574
-
Characterization of two splice variants of human organic anion transporting polypeptide 3A1 isolated from human brain
-
10.1152/ajpcell.00597.2005 1:CAS:528:DC%2BD2sXjt1Gmurs%3D
-
Huber RD, Gao B, Sidler Pfändler MA, et al. Characterization of two splice variants of human organic anion transporting polypeptide 3A1 isolated from human brain. Am J Physiol. 2007;292(2):C795-806.
-
(2007)
Am J Physiol
, vol.292
, Issue.2
-
-
Huber, R.D.1
Gao, B.2
Sidler Pfändler, M.A.3
-
24
-
-
73949149076
-
Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes
-
19748977 10.1093/jac/dkp335 1:CAS:528:DC%2BD1MXht1OqtLfP
-
Janneh O, Chandler B, Hartkoorn R, et al. Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes. J Antimicrob Chemother. 2009;64(5):1002-7.
-
(2009)
J Antimicrob Chemother
, vol.64
, Issue.5
, pp. 1002-1007
-
-
Janneh, O.1
Chandler, B.2
Hartkoorn, R.3
-
25
-
-
84894019074
-
SLCO3A1 expression is a major determinant of atazanavir PBMC penetration in HIV infected patients
-
Siccardi M, D'Avolio A, Baietto L, et al. SLCO3A1 expression is a major determinant of atazanavir PBMC penetration in HIV infected patients. J Int AIDS Soc. 2010;13(Suppl 4):P178.
-
(2010)
J Int AIDS Soc
, vol.13
, Issue.SUPPL. 4
, pp. 178
-
-
Siccardi, M.1
D'Avolio, A.2
Baietto, L.3
|