Papuamine and haliclonadiamine, obtained from an Indonesian sponge Haliclona sp., inhibited cell proliferation of human cancer cell lines

Natural Product Research

Volumn 27, Issue 11, 2013, Pages 1012-1015

  Yamazaki, Hiroyuki ^a   Wewengkang, Defny S ^a,b   Kanno, Syu Ichi ^a   Ishikawa, Masaaki ^a   Rotinsulu, Henki ^a   Mangindaan, Remy E P ^b   Namikoshi, Michio ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^b SAM RATULANGI UNIVERSITY   (Indonesia)

Author keywords

apoptosis; cytotoxicity; Haliclona sp.; haliclonadiamine; marine sponge; papuamine

Indexed keywords

ANTINEOPLASTIC AGENT; HALICLONADIAMINE; NATURAL PRODUCT; PAPUAMINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOASSAY; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE G1 PHASE; CELL LINE; CELL PROLIFERATION; CELL STRAIN CACO 2; CELL STRAIN HCT 15; CELL STRAIN LNCAP; CELL STRAIN MCF 7; CHROMATIN CONDENSATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; FLOW CYTOMETRY; FRAGMENTATION REACTION; HALICLONA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IC 50; LYMPHOMA;

ALKALOIDS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; HUMANS; PORIFERA;

HALICLONA SP.;

EID: 84879618301     PISSN: 14786419     EISSN: 14786427     Source Type: Journal    
DOI: 10.1080/14786419.2012.688050     Document Type: Article

References (5)

1. Baker, B.J., Scheuer, P.J., & Shoolery, J.N. (1988). Papuamine, an antifungal pentacyclic alkaloid from a marine sponge, Haliclona sp. Journal of the American Chemical Society, 110, 965-966.
2. Blunt, J.W., Copp, B.R., Munro, M.H.G., Northcote, P.T., & Prinsep, M.R. (2011). Marine natural products. Natural Product Reports, 28, 196-268, and previous reports in this series.
3. Fahy, E., Molinski, T.F., Harper, M.K., Sullivan, B.W., Faulkner, D.J., Parkanyi, L., & Clardy, J. (1988). Haliclonadiamine, an antimicrobial alkaloid from the sponge Haliclona sp. Tetrahedron Letters, 29, 3427-3428.
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