Nanoplasmonic quantitative detection of intact viruses from unprocessed whole blood

ACS Nano

Volumn 7, Issue 6, 2013, Pages 4733-4745

  Inci, Fatih ^a   Tokel, Onur ^a   Wang, Shuqi ^a   Gurkan, Umut Atakan ^a,c   Tasoglu, Savas ^a   Kuritzkes, Daniel R ^a   Demirci, Utkan ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

AIDS; HIV; nanoplasmonic; Nanotechnology; point of care; viral load

Indexed keywords

AIDS; HIV; NANOPLASMONIC; POINT OF CARE; VIRAL LOAD;

BLOOD; DISEASES; HEALTH RISKS; NANOTECHNOLOGY; POLYMERASE CHAIN REACTION; SURFACE CHEMISTRY; TECHNOLOGY;

VIRUSES;

POLYSTYRENE DERIVATIVE;

ARTICLE; BLOOD; CHEMISTRY; GENETIC PROCEDURES; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; ISOLATION AND PURIFICATION; METHODOLOGY; NANOTECHNOLOGY; PHYSIOLOGY; REPRODUCIBILITY; VIROLOGY; VIRUS LOAD;

BIOSENSING TECHNIQUES; BLOOD; HIV; HUMANS; NANOTECHNOLOGY; POLYSTYRENES; REPRODUCIBILITY OF RESULTS; VIRAL LOAD;

EID: 84879614888     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn3036232     Document Type: Article

References (68)

1. Berkley, S.; Bertram, K.; Delfraissy, J.-F.; Draghia-Akli, R.; Fauci, A.; Hallenbeck, C.; Kagame, M. J.; Kim, P.; Mafubelu, D.; Makgoba, M. W. et al. The 2010 Scientific Strategic Plan of the Global HIV Vaccine Enterprise Nat. Med. 2010, 16, 981-989
2. World Health Organization, Global Health Observatory (GHO)-HIV/AIDS. 2012, Available at: www.who.int/gho/hiv/en/index.html. Accessed May 4, 2013.
3. Wang, S.; Xu, F.; Demirci, U. Advances in Developing HIV-1 Viral Load Assays for Resource-Limited Settings Biotechnol. Adv. 2010, 28, 770-781
4. Karst, S. M. Pathogenesis of Noroviruses, Emerging RNA Viruses Viruses 2010, 2, 748-781
5. Kulinski, M. D.; Mahalanabis, M.; Gillers, S.; Zhang, J. Y.; Singh, S.; Klapperich, C. M. Sample Preparation Module for Bacterial Lysis and Isolation of DNA from Human Urine Biomed. Microdevices 2009, 11, 671-678
6. White, R. A.; Blainey, P. C.; Fan, H. C.; Quake, S. R. Digital PCR Provides Sensitive and Absolute Calibration for High Throughput Sequencing BMC Genomics 2009, 10
7. Wang, S.; Inci, F.; Chaunzwa, T. L.; Ramanujam, A.; Vasudevan, A.; Subramanian, S.; Ip, A. C. F.; Sridharan, B.; Gurkan, U. A.; Demirci, U. Portable microfluidic chip for detection of Escherichia coli in produce and blood International Journal of Nanomedicine 2012, 7, 2591-2600
8. Tasoglu, S.; Gurkan, U. A.; Wang, A.; Demirci, U. Manipulating biological agents and cells in microscale volumes for applications in medicine. Chemical Society Reviews 2013; DOI 10.1039/C3CS60042D.
9. Shafiee, H.; Jahangir, M.; Inci, F.; Wang, S.; Willenbrecht, R. B. M.; Giguel, F. F.; Tsibris, A. M. N.; Kuritzkes, D. R.; Demirci, U. Acute On-Chip HIV Detection Through Label-Free Electrical Sensing of Viral Nano-Lysate. Small 2013; DOI 10.1002/smll.201202195.
10. Kim, Y.-G.; Moon, S.; Kuritzkes, D. R.; Demirci, U. Quantum Dot-Based HIV Capture and Imaging in a Microfluidic Channel Biosens. Bioelectron. 2009, 25, 253-258
11. Gurkan, U. A.; Moon, S.; Geckil, H.; Xu, F.; Wang, S.; Lu, T. J.; Demirci, U. Miniaturized Lensless Imaging Systems for Cell and Microorganism Visualization in Point-of-Care Testing Biotechnol. J. 2011, 6, 138-149
12. Williams, E. H.; Schreifels, J. A.; Rao, M. V.; Davydov, A. V.; Oleshko, V. P.; Lin, N. J.; Steffens, K. L.; Krylyuk, S.; Bertness, K. A.; Manocchi, A. K. et al. Selective Streptavidin Bioconjugation on Silicon and Silicon Carbide Nanowires for Biosensor Applications J. Mater. Res. 2012, 1-10
13. Zhang, G.-J.; Zhang, L.; Huang, M. J.; Luo, Z. H. H.; Tay, G. K. I.; Lim, E.-J. A.; Kang, T. G.; Chen, Y. Silicon Nanowire Biosensor for Highly Sensitive and Rapid Detection of Dengue Virus Sens. Actuators, B 2010, 146, 138-144
14. Kuzmych, O.; Allen, B. L.; Star, A. Carbon Nanotube Sensors for Exhaled Breath Components Nanotechnology 2007, 18
15. Barone, P. W.; Strano, M. S. Single Walled Carbon Nanotubes as Reporters for The Optical Detection of Glucose J. Diabetes Sci. Technol. 2009, 3, 242-252
16. Patolsky, F.; Zheng, G.; Lieber, C. M. Nanowire Sensors for Medicine and the Life Sciences Nanomedicine (London, U. K.) 2006, 1, 51-65
17. Irvine, D. J. Drug Delivery One Nanoparticle, One Kill Nat. Mater. 2011, 10, 342-343
18. Larguinho, M.; Baptista, P. V. Gold and Silver Nanoparticles for Clinical Diagnostics-From Genomics to Proteomics J. Proteomics 2012, 75, 2811-2823
19. Willets, K. A.; Van Duyne, R. P. Localized Surface Plasmon Resonance Spectroscopy and Sensing Annu. Rev. Phys. Chem. 2007, 58, 267-297
20. Chau, L.-K.; Lin, Y.-F.; Cheng, S.-F.; Lin, T.-J. Fiber-optic Chemical and Biochemical Probes Based on Localized Surface Plasmon Resonance Sens. Actuators, B 2006, 113, 100-105
21. Law, W.-C.; Yong, K.-T.; Baev, A.; Prasad, P. N. Sensitivity Improved Surface Plasmon Resonance Biosensor for Cancer Biomarker Detection Based on Plasmonic Enhancement ACS Nano 2011, 5, 4858-4864
22. Endo, T.; Kerman, K.; Nagatani, N.; Takamura, Y.; Tamiya, E. Label-Free Detection of Peptide Nucleic Acid-DNA Hybridization Using Localized Surface Plasmon Resonance Based Optical Biosensor Anal. Chem. 2005, 77, 6976-6984
23. Drachev, V. P.; Perminov, S. V.; Rautian, S. G. Optics of Metal Nanoparticle Aggregates with Light Induced Motion Opt. Express 2007, 15, 8639-8648
24. Nair, T. M.; Myszka, D. G.; Davis, D. R. Surface Plasmon Resonance Kinetic Studies of the HIV TAR RNA Kissing Hairpin Complex and Its Stabilization by 2-Thiouridine Modification Nucleic Acids Res. 2000, 28, 1935-1940
25. Myszka, D. G.; Sweet, R. W.; Hensley, P.; Brigham-Burke, M.; Kwong, P. D.; Hendrickson, W. A.; Wyatt, R.; Sodroski, J.; Doyle, M. L. Energetics of The HIV Gp120-CD4 Binding Reaction Proc. Natl. Acad. Sci. U.S.A. 2000, 97, 9026-9031
26. Haynes, C. L.; Van Duyne, R. P. Nanosphere Lithography: A Versatile Nanofabrication Tool for Studies of Size-Dependent Nanoparticle Optics J. Phys. Chem. B 2001, 105, 5599-5611
27. Mayer, K. M.; Hafner, J. H. Localized Surface Plasmon Resonance Sensors Chem. Rev. 2011, 111, 3828-3857
28. Day, E. S.; Bickford, L. R.; Slater, J. H.; Riggall, N. S.; Drezek, R. A.; West, J. L. Antibody-Conjugated Gold-Gold Sulfide Nanoparticles as Multifunctional Agents for Imaging and Therapy of Breast Cancer Int. J. Nanomed. 2010, 5, 445-454
29. Wang, S.; Esfahani, M.; Gurkan, U. A.; Inci, F.; Kuritzkes, D. R.; Demirci, U. Efficient On-Chip Isolation of HIV Subtypes Lab Chip 2012, 12, 1508-1515
30. Taylor, B. N.; Kuyatt, C. E. Guidelines for Evaluating and Expressing the Uncertainty of NIST Measurement Results. NIST Technical Note 1297 1994, Available at: http://physics.nist.gov/Pubs/guidelines/TN1297/tn1297s.pdf. Accessed May 4, 2013.
31. Wang, W.; Liang, L.; Johs, A.; Gu, B. Thin Films of Uniform Hematite Nanoparticles: Control of Surface Hydrophobicity and Self-Assembly J. Mater. Chem. 2008, 18, 5770-5775
32. Weinrib, H.; Meiri, A.; Duadi, H.; Fixler, D. Uniformly Immobilizing Gold Nanorods on a Glass Substrate J. At., Mol., Opt. Phys. 2012, 2012, 6
33. Haes, A. J.; Van Duyne, R. P. A Nanoscale Optical Biosensor: Sensitivity and Selectivity of an Approach Based on the Localized Surface Plasmon Resonance Spectroscopy of Triangular Silver Nanoparticles J. Am. Chem. Soc. 2002, 124, 10596-10604
34. Van Duyne, R. P.; Haes, A. J.; McFarland, A. D. Nanoparticle Optics: Sensing with Nanoparticle Arrays and Single Nanoparticles. In Physical Chemistry of Interfaces and Nanomaterials II; Lian, T.; Dai, H. L., Eds.; 2003; 5223, 197-207.
35. Wei, Q. H.; Su, K. H.; Durant, S.; Zhang, X. Plasmon Resonance of Finite One-Dimensional Au Nanoparticle Chains Nano Lett. 2004, 4, 1067-1071
36. Sonnichsen, C.; Reinhard, B. M.; Liphardt, J.; Alivisatos, A. P. A Molecular Ruler Based on Plasmon Coupling of Single Gold and Silver Nanoparticles Nat. Biotechnol. 2005, 23, 741-745
37. Haes, A. J.; Zou, S. L.; Schatz, G. C.; Van Duyne, R. P. Nanoscale Optical Biosensor: Short Range Distance Dependence of the Localized Surface Plasmon Resonance of Noble Metal Nanoparticles J. Phys. Chem. B 2004, 108, 6961-6968
38. Anker, J. N.; Hall, W. P.; Lyandres, O.; Shah, N. C.; Zhao, J.; Van Duyne, R. P. Biosensing with Plasmonic Nanosensors Nat. Mater. 2008, 7, 442-453
39. Yu, H.; Kim, K.; Ma, K.; Lee, W.; Choi, J.-W.; Yun, C.-O.; Kim, D. Enhanced Detection of Virus Particles by Nanoisland-Based Localized Surface Plasmon Resonance Biosens. Bioelectron. 2013, 41, 249-255
40. Castelnuovo, B.; Sempa, J.; Agnes, K. N.; Kamya, M. R.; Manabe, Y. C. Evaluation of WHO Criteria for Viral Failure in Patients on Antiretroviral Treatment in Resource-Limited Settings AIDS Res. Treat. 2011, 736938
41. World Health Organization. Antiretroviral Therapy for HIV Infection in Adults and Adolescents, Recommendations for a Public Health Approach, 2010 revision. 2010, Available at http://whqlibdoc.who.int/publications/2010/ 9789241599764-eng.pdf. Accessed May 4, 2013.
42. Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults And Adolescents. 2011, Available at http://www.aidsinfo.nih.gov/ContentFiles/ AdultandAdolescentGL.pdf. Accessed May 4, 2013.
43. World Health Organization. Rapid Advice: Antiretroviral Therapy for HIV Infection in Adults and Adolescents. 2009, Available at http://www.who.int/hiv/ pub/arv/rapid-advice-art.pdf. Accessed May 4, 2013.
44. Mee, P.; Fielding, K. L.; Charalambous, S.; Churchyard, G. J.; Grant, A. D. Evaluation of the WHO Criteria for Antiretroviral Treatment Failure among Adults in South Africa AIDS 2008, 22, 1971-1977
45. van Oosterhout, J. J. G.; Brown, L.; Weigel, R.; Kumwenda, J. J.; Mzinganjira, D.; Saukila, N.; Mhango, B.; Hartung, T.; Phiri, S.; Hosseinipour, M. C. Diagnosis of Antiretroviral Therapy Failure in Malawi: Poor Performance of Clinical and Immunological WHO Criteria Trop. Med. Int. Health 2009, 14, 856-861
46. Jokerst, J. V.; Floriano, P. N.; Christodoulides, N.; Simmons, G. W.; McDevitt, J. T. Integration of Semiconductor Quantum Dots into Nano-bio-chip Systems for Enumeration of CD4+T Cell Counts at the Point-of-Need Lab Chip 2008, 8, 2079-2090
47. Moon, S.; Gurkan, U. A.; Blander, J.; Fawzi, W. W.; Aboud, S.; Mugusi, F.; Kuritzkes, D. R.; Demirci, U. Enumeration of CD4(+) T-Cells Using a Portable Microchip Count Platform in Tanzanian HIV-Infected Patients PLoS One 2011, 6
48. UNAIDS. 2008 Report on the Global AIDS Epidemic. 2008, Available at http://data.unaids.org/pub/GlobalReport/2008/JC1510-2008GlobalReport-en.zip. Accessed May 4, 2013.
49. Newell, M. L.; Coovadia, H.; Cortina-Borja, M.; Rollins, N.; Gaillard, P.; Dabis, F. Mortality of Infected and Uninfected Infants Born to HIV-Infected Mothers in Africa: A Pooled Analysis Lancet 2004, 364, 1236-1243
50. Rouet, F.; Fassinou, P.; Inwoley, A.; Anaky, M. F.; Kouakoussui, A.; Rouzioux, C.; Blanche, S.; Msellati, P. Long-Term Survival and Immuno-Virological Response of African HIV-1-Infected Children to Highly Active Antiretroviral Therapy Regimens AIDS 2006, 20, 2315-2319
51. Busch, M. P.; Satten, G. A. Time Course of Viremia and Antibody Seroconversion Following Human Immunodeficiency Virus Exposure Am. J. Med. 1997, 102, 117-124
52. Lujan-Zilbermann, J.; Rodriguez, C. A.; Emmanuel, P. J. Pediatric HIV Infection: Diagnostic Laboratory Methods Fetal Pediatr. Pathol. 2006, 25, 249-260
53. Ozcan, A.; Demirci, U. Ultra Wide-Field Lens-Free Monitoring of Cells On-Chip Lab Chip 2008, 8, 98-106
54. Alyassin, M. A.; Moon, S.; Keles, H. O.; Manzur, F.; Lin, R. L.; Haeggstrom, E.; Kuritzkes, D. R.; Demirci, U. Rapid Automated Cell Quantification on HIV Microfluidic Devices Lab Chip 2009, 9, 3364-3369
55. Wang, S.; Inci, F.; De Libero, G.; Singhal, A.; Demirci, U. Point-of-Care Assays for Tuberculosis: Role of Nanotechnology/Microfluidics Biotechnol. Adv. 2013, 31, 438-449
56. Johnston, M. I.; Fauci, A. S. An HIV Vaccine-Challenges and Prospects N. Engl. J. Med. 2008, 359, 888-890
57. World Health Organization. Technical Brief on HIV Viral Load Technologies (June 2010). 2012. Available at www.who.int/hiv/topics/treatment/tech-brief- 20100601-en.pdf. Accessed May 4, 2013.
58. Wyatt, R.; Kwong, P. D.; Desjardins, E.; Sweet, R. W.; Robinson, J.; Hendrickson, W. A.; Sodroski, J. G. The Antigenic Structure of the HIV Gp120 Envelope Glycoprotein Nature 1998, 393, 705-711
59. Li, Y.; Migueles, S. A.; Welcher, B.; Svehla, K.; Phogat, A.; Louder, M. K.; Wu, X.; Shaw, G. M.; Connors, M.; Wyatt, R. T. et al. Broad HIV-1 Neutralization Mediated by CD4-Binding Site Antibodies Nat. Med. 2007, 13, 1032-1034
60. Wu, X.; Yang, Z. Y.; Li, Y.; Hogerkorp, C. M.; Schief, W. R.; Seaman, M. S.; Zhou, T.; Schmidt, S. D.; Wu, L.; Xu, L. et al. Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1 Science 2010, 329, 856-861
61. Zhou, T.; Xu, L.; Dey, B.; Hessell, A. J.; Van Ryk, D.; Xiang, S. H.; Yang, X.; Zhang, M. Y.; Zwick, M. B.; Arthos, J. et al. Structural Definition of a Conserved Neutralization Epitope on HIV-1 gp120 Nature 2007, 445, 732-737
62. Stohr, K. A Multicentre Collaboration to Investigate the Cause of Severe Acute Respiratory Syndrome Lancet 2003, 361, 1730-1733
63. Tsang, K. W.; Ho, P. L.; Ooi, G. C.; Yee, W. K.; Wang, T.; Chan-Yeung, M.; Lam, W. K.; Seto, W. H.; Yam, L. Y.; Cheung, T. M. et al. A Cluster of Cases of Severe Acute Respiratory Syndrome in Hong Kong N. Engl. J. Med. 2003, 348, 1977-1985
64. Ginocchio, C. C.; McAdam, A. J. Current Best Practices for Respiratory Virus Testing J. Clin. Microbiol. 2011, 49, 44-48
65. Barletta, J. M.; Edelman, D. C.; Constantine, N. T. Lowering the Detection Limits of HIV-1 Viral Load Using Real-Time Immuno-PCR for HIV-1 p24 Antigen Am. J. Clin. Pathol. 2004, 122, 20-27
66. Sun, R.; Ku, J.; Jayakar, H.; Kuo, J. C.; Brambilla, D.; Herman, S.; Rosenstraus, M.; Spadoro, J. Ultrasensitive Reverse Transcription-PCR Assay for Quantitation of Human Immunodeficiency Virus Type 1 RNA in Plasma J. Clin. Microbiol. 1998, 36, 2964-2969
67. Faunt, L. M.; Johnson, M. L. Analysis of Discrete, Time-Sampled Data Using Fourier-Series Method Methods Enzymol. 1992, 210, 340-356
68. Taylor, J. R. An Introduction to Error Analysis: The Study of Uncertainties in Physical Measurements, 2 nd ed.; University Science Books: Mill Valley, CA, 1996.