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Volumn 436, Issue 2, 2013, Pages 162-168

Localization and function of KLF4 in cytoplasm of vascular smooth muscle cell

Author keywords

Actin; Cytoplasm; Cytoskeleton; KLF4; VSMC

Indexed keywords

ACTIN; EXPORTIN 1; KRUPPEL LIKE FACTOR 4; PLATELET DERIVED GROWTH FACTOR BB;

EID: 84879603999     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.05.067     Document Type: Article
Times cited : (18)

References (41)
  • 2
    • 84856144414 scopus 로고    scopus 로고
    • Tissue transglutaminase promotes PDGF/PDGFR-mediated signaling and responses in vascular smooth muscle cells
    • Zemskov E.A., Mikhailenko I., Smith E.P., Belkin A.M. Tissue transglutaminase promotes PDGF/PDGFR-mediated signaling and responses in vascular smooth muscle cells. J. Cell. Physiol. 2012, 227:2089-2096.
    • (2012) J. Cell. Physiol. , vol.227 , pp. 2089-2096
    • Zemskov, E.A.1    Mikhailenko, I.2    Smith, E.P.3    Belkin, A.M.4
  • 3
    • 0031470985 scopus 로고    scopus 로고
    • Role of tyrosine kinases in extracellular matrix-mediated modulation of arterial smooth muscle cell phenotype
    • Hedin U., Thyberg J., Roy J., Dumitrescu A., Tran P.K. Role of tyrosine kinases in extracellular matrix-mediated modulation of arterial smooth muscle cell phenotype. Arterioscler. Thromb. Vasc. Biol. 1997, 17:1977-1984.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 1977-1984
    • Hedin, U.1    Thyberg, J.2    Roy, J.3    Dumitrescu, A.4    Tran, P.K.5
  • 4
    • 61849112774 scopus 로고    scopus 로고
    • Smooth muscle 22 alpha maintains the differentiated phenotype of vascular smooth muscle cells by inducing filamentous actin bundling
    • Han M., Dong L.H., Zheng B., Shi J.H., Wen J.K., Cheng Y. Smooth muscle 22 alpha maintains the differentiated phenotype of vascular smooth muscle cells by inducing filamentous actin bundling. Life Sci. 2009, 84:394-401.
    • (2009) Life Sci. , vol.84 , pp. 394-401
    • Han, M.1    Dong, L.H.2    Zheng, B.3    Shi, J.H.4    Wen, J.K.5    Cheng, Y.6
  • 6
    • 37549065952 scopus 로고    scopus 로고
    • Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein signaling through the myocardin-related transcription factors
    • Lagna G., Ku M.M., Nguyen P.H., Neuman N.A., Davis B.N., Hata A. Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein signaling through the myocardin-related transcription factors. J. Biol. Chem. 2007, 282:37244-37255.
    • (2007) J. Biol. Chem. , vol.282 , pp. 37244-37255
    • Lagna, G.1    Ku, M.M.2    Nguyen, P.H.3    Neuman, N.A.4    Davis, B.N.5    Hata, A.6
  • 7
    • 78549269804 scopus 로고    scopus 로고
    • Nuclear import mechanism for myocardin family members and their correlation with vascular smooth muscle cell phenotype
    • Nakamura S., Hayashi K., Iwasaki K., Fujioka T., Egusa H., Yatani H., Sobue K. Nuclear import mechanism for myocardin family members and their correlation with vascular smooth muscle cell phenotype. J. Biol. Chem. 2010, 285:37314-37323.
    • (2010) J. Biol. Chem. , vol.285 , pp. 37314-37323
    • Nakamura, S.1    Hayashi, K.2    Iwasaki, K.3    Fujioka, T.4    Egusa, H.5    Yatani, H.6    Sobue, K.7
  • 8
    • 33646435815 scopus 로고    scopus 로고
    • KLF4 and KLF5 regulate proliferation, apoptosis and invasion in esophageal cancer cells
    • Yang Y., Goldstein B.G., Chao H.H., Katz J.P. KLF4 and KLF5 regulate proliferation, apoptosis and invasion in esophageal cancer cells. Cancer Biol. Ther. 2005, 4:1216-1221.
    • (2005) Cancer Biol. Ther. , vol.4 , pp. 1216-1221
    • Yang, Y.1    Goldstein, B.G.2    Chao, H.H.3    Katz, J.P.4
  • 9
    • 84871673153 scopus 로고    scopus 로고
    • Role of kruppel-like transcription factors in adipogenesis
    • Wu Z., Wang S. Role of kruppel-like transcription factors in adipogenesis. Dev. Biol. 2013, 373:235-243.
    • (2013) Dev. Biol. , vol.373 , pp. 235-243
    • Wu, Z.1    Wang, S.2
  • 10
    • 77949668668 scopus 로고    scopus 로고
    • Role of Kruppel-like factor 4 in phenotypic switching and proliferation of vascular smooth muscle cells
    • Zheng B., Han M., Wen J.K. Role of Kruppel-like factor 4 in phenotypic switching and proliferation of vascular smooth muscle cells. IUBMB Life 2010, 62:132-139.
    • (2010) IUBMB Life , vol.62 , pp. 132-139
    • Zheng, B.1    Han, M.2    Wen, J.K.3
  • 11
    • 78650897480 scopus 로고    scopus 로고
    • MiR-146a and Kruppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation
    • Sun S.G., Zheng B., Han M., Fang X.M., Li H.X., Miao S.B., Su M., Han Y., Shi H.J., Wen J.K. MiR-146a and Kruppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation. EMBO Rep. 2011, 12:56-62.
    • (2011) EMBO Rep. , vol.12 , pp. 56-62
    • Sun, S.G.1    Zheng, B.2    Han, M.3    Fang, X.M.4    Li, H.X.5    Miao, S.B.6    Su, M.7    Han, Y.8    Shi, H.J.9    Wen, J.K.10
  • 12
    • 79957507517 scopus 로고    scopus 로고
    • ATRA activates and PDGF-BB represses the SM22alpha promoter through KLF4 binding to, or dissociating from, its cis-DNA elements
    • Yu K., Zheng B., Han M., Wen J.K. ATRA activates and PDGF-BB represses the SM22alpha promoter through KLF4 binding to, or dissociating from, its cis-DNA elements. Cardiovasc. Res. 2011, 90:464-474.
    • (2011) Cardiovasc. Res. , vol.90 , pp. 464-474
    • Yu, K.1    Zheng, B.2    Han, M.3    Wen, J.K.4
  • 13
    • 66249114665 scopus 로고    scopus 로고
    • Sp1-dependent activation of KLF4 is required for PDGF-BB-induced phenotypic modulation of smooth muscle
    • Deaton R.A., Gan Q., Owens G.K. Sp1-dependent activation of KLF4 is required for PDGF-BB-induced phenotypic modulation of smooth muscle. Am. J. Physiol. Heart Circ. Physiol. 2009, 296:H1027-1037.
    • (2009) Am. J. Physiol. Heart Circ. Physiol. , vol.296
    • Deaton, R.A.1    Gan, Q.2    Owens, G.K.3
  • 14
    • 69249123287 scopus 로고    scopus 로고
    • Kruppel-like factor 4 inhibits proliferation by platelet-derived growth factor receptor beta-mediated, not by retinoic acid receptor alpha-mediated, phosphatidylinositol 3-kinase and ERK signaling in vascular smooth muscle cells
    • Zheng B., Han M., Bernier M., Zhang X.H., Meng F., Miao S.B., He M., Zhao X.M., Wen J.K. Kruppel-like factor 4 inhibits proliferation by platelet-derived growth factor receptor beta-mediated, not by retinoic acid receptor alpha-mediated, phosphatidylinositol 3-kinase and ERK signaling in vascular smooth muscle cells. J. Biol. Chem. 2009, 284:22773-22785.
    • (2009) J. Biol. Chem. , vol.284 , pp. 22773-22785
    • Zheng, B.1    Han, M.2    Bernier, M.3    Zhang, X.H.4    Meng, F.5    Miao, S.B.6    He, M.7    Zhao, X.M.8    Wen, J.K.9
  • 15
    • 84863367020 scopus 로고    scopus 로고
    • TGF-beta1 downregulates AT1 receptor expression via PKC-delta-mediated Sp1 dissociation from KLF4 and Smad-mediated PPAR-gamma association with KLF4
    • Zhang X.H., Zheng B., Gu C., Fu J.R., Wen J.K. TGF-beta1 downregulates AT1 receptor expression via PKC-delta-mediated Sp1 dissociation from KLF4 and Smad-mediated PPAR-gamma association with KLF4. Arterioscler. Thromb. Vasc. Biol. 2012, 32:1015-1023.
    • (2012) Arterioscler. Thromb. Vasc. Biol. , vol.32 , pp. 1015-1023
    • Zhang, X.H.1    Zheng, B.2    Gu, C.3    Fu, J.R.4    Wen, J.K.5
  • 16
    • 80053642561 scopus 로고    scopus 로고
    • HDAC2 phosphorylation-dependent Klf5 deacetylation and RARalpha acetylation induced by RAR agonist switch the transcription regulatory programs of p21 in VSMCs
    • Zheng B., Han M., Shu Y.N., Li Y.J., Miao S.B., Zhang X.H., Shi H.J., Zhang T., Wen J.K. HDAC2 phosphorylation-dependent Klf5 deacetylation and RARalpha acetylation induced by RAR agonist switch the transcription regulatory programs of p21 in VSMCs. Cell Res. 2011, 21:1487-1508.
    • (2011) Cell Res. , vol.21 , pp. 1487-1508
    • Zheng, B.1    Han, M.2    Shu, Y.N.3    Li, Y.J.4    Miao, S.B.5    Zhang, X.H.6    Shi, H.J.7    Zhang, T.8    Wen, J.K.9
  • 17
    • 40749088154 scopus 로고    scopus 로고
    • HhLIM is a novel F-actin binding protein involved in actin cytoskeleton remodeling
    • Zheng B., Wen J.K., Han M. HhLIM is a novel F-actin binding protein involved in actin cytoskeleton remodeling. FEBS J. 2008, 275:1568-1578.
    • (2008) FEBS J. , vol.275 , pp. 1568-1578
    • Zheng, B.1    Wen, J.K.2    Han, M.3
  • 18
    • 84859488310 scopus 로고    scopus 로고
    • Retinoic acid receptor alpha mediates all-trans-retinoic acid-induced Klf4 gene expression by regulating Klf4 promoter activity in vascular smooth muscle cells
    • Shi J.H., Zheng B., Chen S., Ma G.Y., Wen J.K. Retinoic acid receptor alpha mediates all-trans-retinoic acid-induced Klf4 gene expression by regulating Klf4 promoter activity in vascular smooth muscle cells. J. Biol. Chem. 2012, 287:10799-10811.
    • (2012) J. Biol. Chem. , vol.287 , pp. 10799-10811
    • Shi, J.H.1    Zheng, B.2    Chen, S.3    Ma, G.Y.4    Wen, J.K.5
  • 19
    • 38949151033 scopus 로고    scopus 로고
    • Human heart LIM protein activates atrial-natriuretic-factor gene expression by interacting with the cardiac-restricted transcription factor Nkx2.5
    • Zheng B., Han M., Wen J.K., Zhang R. Human heart LIM protein activates atrial-natriuretic-factor gene expression by interacting with the cardiac-restricted transcription factor Nkx2.5. Biochem. J. 2008, 409:683-690.
    • (2008) Biochem. J. , vol.409 , pp. 683-690
    • Zheng, B.1    Han, M.2    Wen, J.K.3    Zhang, R.4
  • 20
    • 84864394228 scopus 로고    scopus 로고
    • Kruppel-like factor 4 contributes to high phosphate-induced phenotypic switching of vascular smooth muscle cells into osteogenic cells
    • Yoshida T., Yamashita M., Hayashi M. Kruppel-like factor 4 contributes to high phosphate-induced phenotypic switching of vascular smooth muscle cells into osteogenic cells. J. Biol. Chem. 2012, 287:25706-25714.
    • (2012) J. Biol. Chem. , vol.287 , pp. 25706-25714
    • Yoshida, T.1    Yamashita, M.2    Hayashi, M.3
  • 21
    • 80051532504 scopus 로고    scopus 로고
    • Down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4
    • Davis-Dusenbery B.N., Chan M.C., Reno K.E., Weisman A.S., Layne M.D., Lagna G., Hata A. Down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4. J. Biol. Chem. 2011, 286:28097-28110.
    • (2011) J. Biol. Chem. , vol.286 , pp. 28097-28110
    • Davis-Dusenbery, B.N.1    Chan, M.C.2    Reno, K.E.3    Weisman, A.S.4    Layne, M.D.5    Lagna, G.6    Hata, A.7
  • 22
    • 84863556840 scopus 로고    scopus 로고
    • Trichostatin A prevents neointimal hyperplasia via activation of Kruppel like factor 4
    • Kee H.J., Kwon J.S., Shin S., Ahn Y., Jeong M.H., Kook H. Trichostatin A prevents neointimal hyperplasia via activation of Kruppel like factor 4. Vascul. Pharmacol. 2011, 55:127-134.
    • (2011) Vascul. Pharmacol. , vol.55 , pp. 127-134
    • Kee, H.J.1    Kwon, J.S.2    Shin, S.3    Ahn, Y.4    Jeong, M.H.5    Kook, H.6
  • 24
    • 77949740434 scopus 로고    scopus 로고
    • Cyclosporine up-regulates Kruppel-like factor-4 (KLF4) in vascular smooth muscle cells and drives phenotypic modulation in vivo
    • Garvey S.M., Sinden D.S., Schoppee Bortz P.D., Wamhoff B.R. Cyclosporine up-regulates Kruppel-like factor-4 (KLF4) in vascular smooth muscle cells and drives phenotypic modulation in vivo. J. Pharmacol. Exp. Ther. 2010, 333:34-42.
    • (2010) J. Pharmacol. Exp. Ther. , vol.333 , pp. 34-42
    • Garvey, S.M.1    Sinden, D.S.2    Schoppee Bortz, P.D.3    Wamhoff, B.R.4
  • 25
    • 84877601009 scopus 로고    scopus 로고
    • CRM1 blockade by selective inhibitors of nuclear export attenuates kidney cancer growth
    • Inoue H., Kauffman M., Shacham S., Landesman Y., Yang J., Evans C.P., Weiss R.H. CRM1 blockade by selective inhibitors of nuclear export attenuates kidney cancer growth. J. Urol. 2012, 189:2317-2326.
    • (2012) J. Urol. , vol.189 , pp. 2317-2326
    • Inoue, H.1    Kauffman, M.2    Shacham, S.3    Landesman, Y.4    Yang, J.5    Evans, C.P.6    Weiss, R.H.7
  • 27
    • 33846301667 scopus 로고    scopus 로고
    • Serum response factor: master regulator of the actin cytoskeleton and contractile apparatus
    • Miano J.M., Long X., Fujiwara K. Serum response factor: master regulator of the actin cytoskeleton and contractile apparatus. Am. J. Physiol. Cell Physiol. 2007, 292:C70-81.
    • (2007) Am. J. Physiol. Cell Physiol. , vol.292
    • Miano, J.M.1    Long, X.2    Fujiwara, K.3
  • 28
    • 77956260813 scopus 로고    scopus 로고
    • Role of serum response factor in the pathogenesis of disease
    • Miano J.M. Role of serum response factor in the pathogenesis of disease. Lab. Invest. 2010, 90:1274-1284.
    • (2010) Lab. Invest. , vol.90 , pp. 1274-1284
    • Miano, J.M.1
  • 30
    • 34548624377 scopus 로고    scopus 로고
    • Reorganization of the actin cytoskeleton via transcriptional regulation of cytoskeletal/focal adhesion genes by myocardin-related transcription factors (MRTFs/MAL/MKLs)
    • Morita T., Mayanagi T., Sobue K. Reorganization of the actin cytoskeleton via transcriptional regulation of cytoskeletal/focal adhesion genes by myocardin-related transcription factors (MRTFs/MAL/MKLs). Exp. Cell Res. 2007, 313:3432-3445.
    • (2007) Exp. Cell Res. , vol.313 , pp. 3432-3445
    • Morita, T.1    Mayanagi, T.2    Sobue, K.3
  • 31
    • 36849053911 scopus 로고    scopus 로고
    • Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling
    • Morita T., Mayanagi T., Sobue K. Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling. J. Cell Biol. 2007, 179:1027-1042.
    • (2007) J. Cell Biol. , vol.179 , pp. 1027-1042
    • Morita, T.1    Mayanagi, T.2    Sobue, K.3
  • 32
    • 67651036161 scopus 로고    scopus 로고
    • All-trans retinoic acid increases KLF4 acetylation by inducing HDAC2 phosphorylation and its dissociation from KLF4 in vascular smooth muscle cells
    • Meng F., Han M., Zheng B., Wang C., Zhang R., Zhang X.H., Wen J.K. All-trans retinoic acid increases KLF4 acetylation by inducing HDAC2 phosphorylation and its dissociation from KLF4 in vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 2009, 387:13-18.
    • (2009) Biochem. Biophys. Res. Commun. , vol.387 , pp. 13-18
    • Meng, F.1    Han, M.2    Zheng, B.3    Wang, C.4    Zhang, R.5    Zhang, X.H.6    Wen, J.K.7
  • 33
    • 84865864735 scopus 로고    scopus 로고
    • Cooperative binding of KLF4, pELK-1, and HDAC2 to a G/C repressor element in the SM22alpha promoter mediates transcriptional silencing during SMC phenotypic switching in vivo
    • Salmon M., Gomez D., Greene E., Shankman L., Owens G.K. Cooperative binding of KLF4, pELK-1, and HDAC2 to a G/C repressor element in the SM22alpha promoter mediates transcriptional silencing during SMC phenotypic switching in vivo. Circ. Res. 2012, 111:685-696.
    • (2012) Circ. Res. , vol.111 , pp. 685-696
    • Salmon, M.1    Gomez, D.2    Greene, E.3    Shankman, L.4    Owens, G.K.5
  • 34
    • 36248983372 scopus 로고    scopus 로고
    • Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation
    • Evans P.M., Zhang W., Chen X., Yang J., Bhakat K.K., Liu C. Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation. J. Biol. Chem. 2007, 282:33994-34002.
    • (2007) J. Biol. Chem. , vol.282 , pp. 33994-34002
    • Evans, P.M.1    Zhang, W.2    Chen, X.3    Yang, J.4    Bhakat, K.K.5    Liu, C.6
  • 35
    • 84877114086 scopus 로고    scopus 로고
    • Sumoylation of Kruppel-like factor 4 inhibits pluripotency induction but promotes adipocyte differentiation
    • Tahmasebi S., Ghorbani M., Savage P., Yan K., Gocevski G., Xiao L., You L., Yang X.J. Sumoylation of Kruppel-like factor 4 inhibits pluripotency induction but promotes adipocyte differentiation. J. Biol. Chem. 2013, 288:12791-12804.
    • (2013) J. Biol. Chem. , vol.288 , pp. 12791-12804
    • Tahmasebi, S.1    Ghorbani, M.2    Savage, P.3    Yan, K.4    Gocevski, G.5    Xiao, L.6    You, L.7    Yang, X.J.8
  • 37
    • 15744367559 scopus 로고    scopus 로고
    • Kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression
    • Liu Y., Sinha S., McDonald O.G., Shang Y., Hoofnagle M.H., Owens G.K. Kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression. J. Biol. Chem. 2005, 280:9719-9727.
    • (2005) J. Biol. Chem. , vol.280 , pp. 9719-9727
    • Liu, Y.1    Sinha, S.2    McDonald, O.G.3    Shang, Y.4    Hoofnagle, M.H.5    Owens, G.K.6
  • 38
    • 77952880766 scopus 로고    scopus 로고
    • Astaxanthin improves the proliferative capacity as well as the osteogenic and adipogenic differentiation potential in neural stem cells
    • Kim J.H., Nam S.W., Kim B.W., Kim W.J., Choi Y.H. Astaxanthin improves the proliferative capacity as well as the osteogenic and adipogenic differentiation potential in neural stem cells. Food Chem. Toxicol. 2010, 48:1741-1745.
    • (2010) Food Chem. Toxicol. , vol.48 , pp. 1741-1745
    • Kim, J.H.1    Nam, S.W.2    Kim, B.W.3    Kim, W.J.4    Choi, Y.H.5
  • 39
    • 0037837819 scopus 로고    scopus 로고
    • Kruppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor beta 1 in the regulation of vascular smooth muscle cell phenotype
    • King K.E., Iyemere V.P., Weissberg P.L., Shanahan C.M. Kruppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor beta 1 in the regulation of vascular smooth muscle cell phenotype. J. Biol. Chem. 2003, 278:11661-11669.
    • (2003) J. Biol. Chem. , vol.278 , pp. 11661-11669
    • King, K.E.1    Iyemere, V.P.2    Weissberg, P.L.3    Shanahan, C.M.4


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